Secondary Faculty

Michael Cappello MD is Professor and Chair of the Department of Epidemiology of Microbial Diseases at the Yale School of Public Health, and Professor of Pediatrics and Microbial Pathogenesis at Yale Medical School. He graduated from Brown University with a degree in Biomedical Ethics and received his MD from Georgetown University in Washington, DC. After training in adult and Pediatric infectious diseases at Yale, Dr. Cappello joined the faculty in 1995, where he oversees a laboratory and field based research program focused on global health, tropical medicine and molecular parasitology. He is a 2007 recipient of the Bailey K. Ashford medal, awarded by the American Society of Tropical Medicine and Hygiene “for distinguished work in tropical medicine.” In addition to research, Dr. Cappello provides clinical care as an Infectious Diseases specialist at Yale New Haven Children’s Hospital. He is co-founder of the Yale Partnerships for Global Health, an initiative that advances scientific knowledge, promotes international understanding, and builds human capacity through collaborative research and training. From 2007-15, Dr. Cappello directed the Yale World Fellows Program, a multi-disciplinary, campus-wide initiative whose mission is to cultivate and inspire a global network of leaders committed to positive change. From 2016-21, he chaired the Council on African Studies at the Whitney and Betty MacMillan Center for International and Area Studies and was faculty director of the Yale Africa Initiative. Dr. Cappello is a member of the Council on Foreign Relations and serves on the Academic Advisory Council of Schwarzman Scholars Program at Tsinghua University in Beijing.

My laboratory investigates vector-borne diseases. Studies are directed toward understanding Lyme disease, flaviviral infections including dengue and West Nile viruses, and malaria. Efforts on Lyme disease include exploring immunity to Borrelia burgdorferi, selective B. burgdorferi gene expression in vivo, and the immunobiology of Lyme arthritis. Flaviviruses and Plasmodium are used as models  to understand the molecular interactions between pathogens, their arthropod vectors and their mammalian hosts. Finally, we are developing new  approaches to prevent ticks and mosquitoes from feeding on a vertebrate host, thereby interfering with pathogen transmission.

I received my M.D. and Ph.D. from the University of Chicago in the Medical Scientist Training Program (MSTP). My Ph.D. was from the Department of Molecular Genetics and Cell Biology on the pathogenesis of Herpes simplex virus; followed by medical residency and Infectious Diseases training was at Washington University in St. Louis where I was a Howard Hughes Research Fellow. I joined the Indiana University faculty in 2001 to work on Chlamydia pathogenesis, which remains my research focus to the present day.

Dr. Kazmierczak received her PhD from Rockefeller University (1993) and her MD from Cornell University Medical College (1994), both in New York City. She completed an Internal Medicine residency and Infectious Diseases fellowship training at the University of California, San Francisco, and joined the Yale faculty in 2001. She is currently a Professor of Medicine and Microbial Pathogenesis, and Director of the MD-PhD program at Yale. Dr. Kazmierczak's research program is broadly focused on bacterial and host factors that allow opportunistic infections to occur. Using Pseudomonas aeruginosa as a clinically relevant model, her lab addresses fundamental questions of how cell-envelope spanning bacterial machines - the Type 3 secretion system, Type 4 pili and polar flagellum - are assembled, regulated, and used during infection. She has also identified host responses directed at components of these virulence associated structures, in particular those mediated by the NLRC4 inflammasome. Inflammatory responses to bacteria are also a focus of her work on microbiome-host interactions in infants with Cystic Fibrosis, where her lab has used longitudinal data acquired over five years from cohorts of patients and controls to understand gut microbiome composition and the inflammatory and metabolic responses at this site. Dr. Kazmierczak has been recognized as a Burroughs-Wellcome Fund Investigator in the Pathogenesis of Infectious Diseases (2007), a Donaghue Investigator (2002), and a Hellman Family Fellow (2002). She is a Fellow of the Infectious Diseases Society of America and an elected member of the American Society for Clinical Investigation and the American Academy for Microbiology.

Dr. Priti Kumar received her PhD in Immunology from Indian Institute of Science in the year 2002. After completing her postdoctoral studies from Harvard Medical School, she joined as an Assistant Professor at Yale University in the year 2008. Currently, she is Associate Professor of Infectious Diseases at Yale University School of Medicine. Her laboratory conducts translational research with a focus on treatment of diseases caused by RNA viruses. For the last 12 years as faculty at Yale, she made key contributions towards the development and testing of gene therapy and cure based approaches that overcome in vivo biological barriers to enable the use of next-generation biologicals like nucleic acids such as siRNA, nucleases such as recombinases and CRISPRs and antibodies with effector function for their therapeutic potential against viruses like HIV-1, West Nile virus, Japanese encephalitis virus, dengue and now, SARS-COV2. Her laboratory is well-recognized for studies on HIV-1 in state-of-the-art humanized mouse models that allow characterization of virus pathogenesis in the context of a human immune system. Her laboratory also conducts pioneering research on live-imaging pathogenesis of infectious viruses in small animal models.

Dr. Maudry Laurent-Rolle received her B.S. from Long Island University, Brooklyn Campus in Biology in 2001. She then obtained her MD and PhD from Icahn School of Medicine at Mount Sinai. Her dissertation research was funded by an NIH pre-doctoral fellowship, which allowed her to examine the molecular mechanisms by which flaviviruses inhibit host innate immune responses.  She completed residency training in Internal Medicine at Albert Einstein/Montefiore Medical Center in 2016 then joined the Infectious Diseases Fellowship program here at Yale University. Her research focus is on vaccine design and development of antivirals. She is originally from the beautiful Caribbean island of Dominica, known for its many rivers, tropical rainforests, and natural hot springs.

David R. Martinez, Ph.D. studies immunity to viral pathogens of global health importance. David grew up in El Salvador until age 13. As a young child, David became interested in emerging viruses because of innate curiosity in viruses and vaccines as well as his exposure to public health campaigns to fight arthropod-borne viruses (e.g., Dengue virus) and other infectious diseases. David received his Ph.D. from Duke University and trained with leading vaccine immunologist, Dr. Sallie R. Permar, at the Duke Human Vaccine Institute. Following the completion of his doctoral studies, David trained as a postdoctoral scholar with one of the world’s leading coronavirologists, Dr. Ralph Baric, at UNC Chapel Hill before and during the COVID-19 pandemic studying immunity to flaviviruses and coronaviruses. Dr. Martinez was part of the teams that contributed to the development of the FDA-approved and widely used Moderna COVID-19 vaccine and the Johnson & Johnson COVID-19 vaccine which was used under Emergency Use Authorization. Dr. Martinez also contributed to the pre-clinical development of COVID-19 human monoclonal antibody therapies from Eli Lilly and AstraZeneca which also received FDA Emergency Use Authorization. Dr. Martinez is a Hanna H. Gray Faculty Fellow of the Howard Hughes Medical Institute.

Wei Mi obtained his PhD degree in structural biology at Peking University, Beijing, China. Fascinated by structures of membrane proteins, he came to the US and received postdoctoral training at Purdue University, the University of Washington and Harvard Medical School (HMS). At HMS, he joined the laboratory of Dr. Maofu Liao and used single particle cryo-electron microscopy (Cryo-EM) to determine structures of ATP-binding cassette transporters in lipid bilayer environment. In 2019, Dr Mi joined the Department of Pharmacology at Yale University School of Medicine. The focus of his research is to dissect mechanisms of membrane proteins involved in lipopolysaccharide (LPS) synthesis and regulation with genetic, biochemical, and structural approaches.

After finishing his undergraduate studies at Brown University, Dr. Sutton enrolled in the MSTP at Stanford, where he obtained his PhD degree with Dr. John Boothroyd, working on trans-splicing in African trypanosomes. He then completed a categorical residency in internal medicine at the Hospital of the University of Pennsylvania and a fellowship in infectious diseases at UCSF. After post-doctoral stints with Drs. Harold Varmus, Dan Littman, and Pat Brown in which he worked on HTLV cell binding and entry and the development of HIV-based gene therapy vectors, he joined the faculty at Baylor College of Medicine. In 2008 he was recruited to Yale to continue his work on HIV replication and lentiviral vectors. Dr. Sutton spends approximately 50% of his time at the research bench and 25% in the clinical setting, both out-patient and in-patient, mainly at the West Haven VA (VACT). He now the Research Chief of Infectious Diseases at VACT, which takes up 25% of his time. Dr. Sutton was the Chief of Infectious Diseases at VACT from 2013-2024. Dr. Sutton took an administrative leave of absence in mid-April 2022, but he resumed all of his clinical, educational, and research activities before the beginning of 2023. He is permanently physically disabled.