Daniel G. Jovin
MD-PhD Student, MD-PhD ProgramAbout
Research
Publications
2025
Sustained tenascin-C expression drives neointimal hyperplasia and promotes aortocaval fistula failure
Gonzalez L, Zhang W, Bai H, Taniguchi R, Ramachandra A, Jovin D, Ohashi Y, Nguyen M, Thaxton C, Yatsula B, Vazquez-Padron R, Humphrey J, Martin K, Kyriakides T, Dardik A. Sustained tenascin-C expression drives neointimal hyperplasia and promotes aortocaval fistula failure. AJP Heart And Circulatory Physiology 2025, 328: h1147-h1167. PMID: 40247455, PMCID: PMC12150301, DOI: 10.1152/ajpheart.00661.2024.Peer-Reviewed Original ResearchAnimalsArteriovenous Shunt, SurgicalDisease Models, AnimalGraft Occlusion, VascularHuman Umbilical Vein Endothelial CellsHumansHyperplasiaMacrophagesMaleMiceMice, Inbred C57BLMice, KnockoutMyocytes, Smooth MuscleNeointimaNF-kappa BTenascinThrombomodulinVascular PatencyVascular RemodelingVena Cava, InferiorHypercholesterolemia-induced LXR signaling in smooth muscle cells contributes to vascular lesion remodeling and visceral function
Zhang H, de Urturi D, Fernández-Tussy P, Huang Y, Jovin D, Zhang X, Huang S, Lek M, da Silva Catarino J, Sternak M, Citrin K, Swirski F, Gustafsson J, Greif D, Esplugues E, Biwer L, Suárez Y, Fernández-Hernando C. Hypercholesterolemia-induced LXR signaling in smooth muscle cells contributes to vascular lesion remodeling and visceral function. Proceedings Of The National Academy Of Sciences Of The United States Of America 2025, 122: e2417512122. PMID: 40035761, PMCID: PMC11912459, DOI: 10.1073/pnas.2417512122.Peer-Reviewed Original Research
2024
Manifestations of human atherosclerosis across vascular beds
Jovin D, Sumpio B, Greif D. Manifestations of human atherosclerosis across vascular beds. JVS-Vascular Insights 2024, 2: 100089. PMID: 39822712, PMCID: PMC11737335, DOI: 10.1016/j.jvsvi.2024.100089.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2023
Introduction: Fluids
Jovin D, Mortlock R. Introduction: Fluids. The Yale Journal Of Biology And Medicine 2023, 96: 1-2. PMCID: PMC10052594.Commentaries, Editorials and Letters
2022
Vascular pathobiology of pulmonary hypertension
Gallardo-Vara E, Ntokou A, Dave J, Jovin D, Saddouk F, Greif D. Vascular pathobiology of pulmonary hypertension. The Journal Of Heart And Lung Transplantation 2022, 42: 544-552. PMID: 36604291, PMCID: PMC10121751, DOI: 10.1016/j.healun.2022.12.012.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsFlow-induced endothelial mitochondrial remodeling mitigates mitochondrial reactive oxygen species production and promotes mitochondrial DNA integrity in a p53-dependent manner
Shin J, Hong S, Choi S, Rath M, Saredy J, Jovin D, Sayoc J, Park H, Eguchi S, Rizzo V, Scalia R, Wang H, Houser S, Park J. Flow-induced endothelial mitochondrial remodeling mitigates mitochondrial reactive oxygen species production and promotes mitochondrial DNA integrity in a p53-dependent manner. Redox Biology 2022, 50: 102252. PMID: 35121402, PMCID: PMC8818582, DOI: 10.1016/j.redox.2022.102252.Peer-Reviewed Original Research
2021
Eccentric hypertrophy in an animal model of mid- and long-term premature ventricular contraction–induced cardiomyopathy
Torrado J, Kowlgi G, Ramirez R, Balderas-Villalobos J, Jovin D, Parker C, Om E, Airapetov S, Kaszala K, Tan A, Ellenbogen K, Huizar J. Eccentric hypertrophy in an animal model of mid- and long-term premature ventricular contraction–induced cardiomyopathy. Heart Rhythm O2 2021, 2: 80-88. PMID: 34113908, PMCID: PMC8183810, DOI: 10.1016/j.hroo.2020.12.021.Peer-Reviewed Original Research
2020
Coronary artery bypass graft markers: history, usage, and effects
Jovin D, Katlaps G, Sumption K. Coronary artery bypass graft markers: history, usage, and effects. General Thoracic And Cardiovascular Surgery 2020, 68: 453-458. PMID: 32146580, DOI: 10.1007/s11748-020-01325-2.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2019
Consequences of chronic frequent premature atrial contractions: Association with cardiac arrhythmias and cardiac structural changes
Gunda S, Akyeampong D, Gomez‐Arroyo J, Jovin D, Kowlgi N, Kaszala K, Tan A, Koneru J, Kron J, Ellenbogen K, Huizar J. Consequences of chronic frequent premature atrial contractions: Association with cardiac arrhythmias and cardiac structural changes. Journal Of Cardiovascular Electrophysiology 2019, 30: 1952-1959. PMID: 31310360, PMCID: PMC6786912, DOI: 10.1111/jce.14067.Peer-Reviewed Original ResearchAction PotentialsAnimalsAtrial FibrillationAtrial Premature ComplexesCardiomyopathiesChronic DiseaseCross-Sectional StudiesDisease Models, AnimalDogsEchocardiographyElectrocardiography, AmbulatoryFemaleHeart RateHumansMaleRetrospective StudiesRisk AssessmentStroke VolumeTachycardia, SupraventricularTime FactorsVentricular Function, LeftVentricular Premature ComplexesNeuroprotection against stroke and encephalopathy after cardiac surgery
Jovin D, Katlaps K, Ellis B, Dharmaraj B. Neuroprotection against stroke and encephalopathy after cardiac surgery. Bildgebung 2019, 11: 27-37. PMID: 32148901, PMCID: PMC7044570, DOI: 10.1556/1646.11.2019.01.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements