Skip to Main Content


The Yale Liver Center

The Yale Liver Center is one of 17 Digestive Diseases Research Core Centers (DDRCCs) supported by NIH/NIDDK. The Yale Liver Center has been funded continuously since 1984 and is one of only four that focus on the liver. The Yale Liver Center supports investigation of liver structure, function and disease. Research support is provided through the Center’s Four Core Facilities, as well as through Pilot Feasibility Projects that are offered annually.

The research base is focused on three broad areas of liver biology and pathobiology:

  • Immunobiology and Inflammation
  • Hepatic Metabolism
  • Epithelial Biology and Pathobiology
Currently, 34 independent principal investigators are Members of the Center as well as 52 Associate Members, which involves 17 departments at Yale including:

The Liver Center also supports weekly research seminars (on Tuesday afternoons) and clinical lectures (on Friday afternoons), in conjunction with the Section of Digestive Diseases, Department of Internal Medicine.

Jun 202211-12Multiple Days
All Day
Michael Mak - Matthew McConnell, MD - Silvia Vilarinho, MD, PhD - Michael Nathanson, MD, PhD - Mario Strazzabosco, MD, PhD - Guadalupe Garcia-Tsao, MD, FRCP - Yasuko Iwakiri, PhD - Wajahat Mehal, PhD, MD, BA - Raiza Rossi - Saad Saffo, MD - Catherine Mezzacappa, MD, MPH - Praveena Narayanan - Rachel Perry, PhD - Romina Fiorotto, PhD - Gregory Tietjen, PhD - Michael Schilsky, MD - Lloyd G. Cantley, MD - Chen Liu, MD, PhD - Wade Schulz, MD, PhD - James Knight, PhD - Anton Bennett, PhD

The Research Base

The Research Base can be organized to reflect the fact that it is focused on three broad translational themes.

These include:

  1. Immunobiology and inflammation
  2. Hepatic metabolism
  3. Epithelial biology and pathobiology.

The major areas of liver disease examined within these translational themes include autoimmune diseases, cholestasis, fibrosis/cirrhosis, genetic diseases, infections, liver cancer, and NASH/ASH. Many of our investigators have research interests that span multiple themes.

Publication Acknowledgment

To cite the Liver Center in your publications please use the following statement:

”This project was supported in part by the Yale Liver Center award NIH P30 DK034989 ________ core.”
(insert name of core(s) that you used-Morphology, Cellular Molecular, Clinical-Translational)