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Pilot Feasibility Grants

2019-2020 Applications


The NIH P30 Liver Center grant provides for the annual submission of pilot projects (up to $25,000 direct costs each) from both Yale and non-Yale Liver Center investigators as approved by the Executive Committee.

The purposes of the pilots are to fund new initiatives, not ongoing research, and to support new investigators to pursue liver related research that should lead to future R01-type funding or other support. Projects utilizing Core Facilities and supporting young investigators or applying new methodologies or approaches to the study of liver pathophysiology are given priority if the science is equally meritorious. Projects that will not make use of the Liver Center Core Facilities will not be considered. Clinical trials are not allowed.

Investigators should meet one of the following criteria, in order of priority:

  1. Senior fellows or junior faculty at Yale, currently not funded by NIH grants and in need of funds to help prepare for R01-type applications.
  2. Established University investigators not currently funded for work related to the Center’s focus but who wish to apply their areas of expertise to subjects of Center interest.
  3. Funded Center investigators who wish to pursue a project that is different from their current focus of interest, and who need to develop preliminary data to apply for new R01-type funding.
  4. **We are also accepting submissions for special pilots specifically associated with some aspect related to the biology, pathogenesis, and/or therapy of primary sclerosing cholangititis including basic studies related to cholestasis**

An internal review by the Center’s Executive Committee must precede submission of pilot project requests to our External Advisory Board. This Board will convene at Yale in May to determine a priority score for each request and can approve or disapprove the project or modify the budget.

According to our guidelines, no pilot projects can be submitted for more than two consecutive years. All current pilot project recipients must follow the same guidelines to request a second year of funding.

Important Dates

Please note the following dates on your calendar:

Friday, February 15, 2019
Deadline for submission of Letter of Intent (one electronic copy) emailed to Christine Abu-Hanna by 5:00pm.

The letter of intent must include the following:

  1. Title of pilot project and
  2. A sentence as to the applicability of the pilot project to the Liver Center.

Upon Letter of Intent review by the Executive Committee, applicants will be notified whether or not they can submit a full grant application;

Friday, March 15, 2019
Deadline for submission of full applications (one electronic copy) emailed to Christine Abu-Hanna by 5:00pm. This should include all documents listed below. Due to pilot projects being internally funded, a TranSum and Office of Sponsored Projects approval/signature is not required.

Monday, April 29, 2019
Internal reviews of all applications are returned to investigators for revisions.

Monday, May 27, 2019
Receipt of revised application deadline (one electronic copy) emailed to Christine Abu-Hanna by 5:00pm.

Monday, June 24, 2019
External Advisory Board meets at Yale to make final decisions on awards. Applicants will be expected to present their pilot project to the Board on this date (approximately 15 minutes).

September 1, 2019
Approved projects will begin funding period.

Format of applications

The general format of the NIH research project applications on fillable individual PHS 398 forms Rev. 1/18 approved through 03/31/2020 must be used to request pilot funding. Please only use forms listed in the instructions and submit in the order listed. To download forms, please click here. If using the PDF forms, Adobe Acrobat Professional software is required to save/edit your application on the forms required when submitting your application. Instructions for grant applications can be found on the left hand side of this page or by clicking here. Please only include the forms listed.


If you have any questions, please contact Christine Abu-Hanna by email or 203-785-5610.