Stephen Baldassarri, MD, MHS
Research & Publications
Biography
News
Research Summary
My main goal is to improve human health through original research, clinical care, and education using a team-oriented multidisciplinary approach. My research focuses on understanding mechanisms of addiction and sleep through novel neuroimaging techniques, clinical trials, and observational studies. I collaborate closely with a variety of experts in different fields: General Medicine, various medical specialties (Addiction, Pulmonary, Critical Care, Sleep, Emergency, and Laboratory Medicine), Psychiatry, Psychology, Biomedical Imaging, Engineering, Chemistry, Law, and Public Health. I seek to build bridges between disciplines to increase the impact of new discoveries.
Coauthors
Research Interests
Critical Care; Internal Medicine; Opioid-Related Disorders; Neurosciences; Nicotine; Psychopharmacology; Sleep; Tobacco Use Disorder; Pulmonary Medicine; Acute Lung Injury; Neuroimaging; Electronic Nicotine Delivery Systems; Addiction Medicine; Marijuana Use
Research Image
Measurement of brain beta-2 nicotinic acetylcholine receptor occupancy in humans
Selected Publications
- Varenicline for E-Cigarette Cessation in Adults: A Preliminary Placebo-Controlled Randomized TrialFucito L, Baldassarri S, Baker N, Palmer A, O'Malley S, Carpenter M, Krishnan-Sarin S, Gray K, Toll B. Varenicline for E-Cigarette Cessation in Adults: A Preliminary Placebo-Controlled Randomized Trial. American Journal Of Preventive Medicine 2024 PMID: 38752949, DOI: 10.1016/j.amepre.2024.04.007.
- 0495 Association of Cannabis Use and Symptoms Among Patients with Obstructive Sleep ApneaInaya A, Baldassarri S, Sands S, Yaggi H, Wellman A, Redeker N, Zinchuk A. 0495 Association of Cannabis Use and Symptoms Among Patients with Obstructive Sleep Apnea. Sleep 2024, 47: a213-a213. DOI: 10.1093/sleep/zsae067.0495.
- Sleep Deficiency and Pain in Persons With Substance Use DisordersBuonora M, Sharma M, Falker C, Baldassarri S. Sleep Deficiency and Pain in Persons With Substance Use Disorders. Current Addiction Reports 2024, 11: 447-458. DOI: 10.1007/s40429-024-00562-2.
- A new perspective on mitigating lung cancer risks through smoking cessation and reductionFucito L, Palmer A, Baldassarri S. A new perspective on mitigating lung cancer risks through smoking cessation and reduction. Journal Of The National Cancer Institute 2024, 116: 782-785. PMID: 38497951, PMCID: PMC11160493, DOI: 10.1093/jnci/djae044.
- A randomized controlled trial of potential tobacco policies prohibiting menthol flavor in cigarettes and e-cigarettes: a study protocolBold K, Sharma A, Haeny A, Gueorguieva R, Buta E, Baldassarri S, Lempert L, Krishnan-Sarin S, O’Malley S. A randomized controlled trial of potential tobacco policies prohibiting menthol flavor in cigarettes and e-cigarettes: a study protocol. BMC Psychiatry 2024, 24: 201. PMID: 38475757, PMCID: PMC10935798, DOI: 10.1186/s12888-024-05619-0.
- Marijuana Vaping in U.S. Adults: Evidence From the Behavioral Risk Factor Surveillance SystemBaldassarri SR, Camenga DR, Fiellin DA, Friedman AS. Marijuana Vaping in U.S. Adults: Evidence From the Behavioral Risk Factor Surveillance System. American Journal Of Preventive Medicine 2020, 59: 449-454. PMID: 32684361, PMCID: PMC7484388, DOI: 10.1016/j.amepre.2020.03.014.
- Correlates of sleep quality and excessive daytime sleepiness in people with opioid use disorder receiving methadone treatmentBaldassarri SR, Beitel M, Zinchuk A, Redeker NS, Oberleitner DE, Oberleitner LMS, Carrasco D, Madden LM, Lipkind N, Fiellin DA, Bastian LA, Chen K, Yaggi HK, Barry DT. Correlates of sleep quality and excessive daytime sleepiness in people with opioid use disorder receiving methadone treatment. Sleep And Breathing 2020, 24: 1729-1737. PMID: 32556918, PMCID: PMC7680294, DOI: 10.1007/s11325-020-02123-z.
- Inverse changes in raphe and cortical 5‐HT1B receptor availability after acute tryptophan depletion in healthy human subjectsBaldassarri SR, Park E, Finnema SJ, Planeta B, Nabulsi N, Najafzadeh S, Ropchan J, Huang Y, Hannestad J, Maloney K, Bhagwagar Z, Carson RE. Inverse changes in raphe and cortical 5‐HT1B receptor availability after acute tryptophan depletion in healthy human subjects. Synapse 2020, 74: e22159. PMID: 32324935, PMCID: PMC7426238, DOI: 10.1002/syn.22159.
- Vaping—Seeking Clarity in a Time of UncertaintyBaldassarri SR, Fiellin DA, Friedman AS. Vaping—Seeking Clarity in a Time of Uncertainty. JAMA 2019, 322: 1951-1952. PMID: 31697311, PMCID: PMC8284981, DOI: 10.1001/jama.2019.16493.
- Electronic cigarette and tobacco use in individuals entering methadone or buprenorphine treatmentBaldassarri SR, Fiellin DA, Savage ME, Madden LM, Beitel M, Dhingra LK, Fucito L, Camenga D, Bollampally P, Barry DT. Electronic cigarette and tobacco use in individuals entering methadone or buprenorphine treatment. Drug And Alcohol Dependence 2019, 197: 37-41. PMID: 30769264, PMCID: PMC6637405, DOI: 10.1016/j.drugalcdep.2018.12.012.
- Electronic cigarettes for adults with tobacco dependence enrolled in a tobacco treatment program: A pilot studyBaldassarri SR, Bernstein SL, Chupp GL, Slade MD, Fucito LM, Toll BA. Electronic cigarettes for adults with tobacco dependence enrolled in a tobacco treatment program: A pilot study. Addictive Behaviors 2017, 80: 1-5. PMID: 29304395, PMCID: PMC6463885, DOI: 10.1016/j.addbeh.2017.11.033.
- Use of Electronic Cigarettes Leads to Significant Beta2-Nicotinic Acetylcholine Receptor Occupancy: Evidence From a PET Imaging StudyBaldassarri SR, Hillmer AT, Anderson JM, Jatlow P, Nabulsi N, Labaree D, Cosgrove KP, O’Malley S, Eissenberg T, Krishnan-Sarin S, Esterlis I. Use of Electronic Cigarettes Leads to Significant Beta2-Nicotinic Acetylcholine Receptor Occupancy: Evidence From a PET Imaging Study. Nicotine & Tobacco Research 2017, 20: 425-433. PMID: 28460123, PMCID: PMC5896427, DOI: 10.1093/ntr/ntx091.
- Practise Patterns and Perceptions of Chest Health Care Providers on Electronic Cigarette Use: An In-Depth Discussion and Report of Survey ResultsBaldassarri SR, Chupp GL, Leone FT, Warren GW, Toll BA. Practise Patterns and Perceptions of Chest Health Care Providers on Electronic Cigarette Use: An In-Depth Discussion and Report of Survey Results. The Journal Of Smoking Cessation 2017, 13: 72-77. PMID: 29881469, PMCID: PMC5985665, DOI: 10.1017/jsc.2017.6.
- A Comprehensive Approach to Tobacco Dependence InterventionsBaldassarri SR, Toll BA, Leone FT. A Comprehensive Approach to Tobacco Dependence Interventions. The Journal Of Allergy And Clinical Immunology In Practice 2015, 3: 481-488. PMID: 25982231, DOI: 10.1016/j.jaip.2015.04.007.
Clinical Trials
Conditions | Study Title |
---|---|
Addictive Behaviors; Tobacco Addiction | Varenicline for treatment of e-cigarette dependence |
Diseases of the Nervous System; Mental Health & Behavioral Research | Examination of Glutamate and mGluR5 in Psychiatric Disorders |
Mental Health & Behavioral Research | Imaging mGluR5 and synaptic density in psychiatric disorders |