2017
Tumor Emboli: A Rare Cause of Acute Pulmonary Hypertension
Mainardi A, Trow T. Tumor Emboli: A Rare Cause of Acute Pulmonary Hypertension. The American Journal Of Medicine 2017, 130: e137-e139. PMID: 28159185, DOI: 10.1016/j.amjmed.2016.11.023.Peer-Reviewed Original Research
2014
Pharmacologic Therapy for Pulmonary Arterial Hypertension in Adults CHEST Guideline and Expert Panel Report
Taichman DB, Ornelas J, Chung L, Klinger JR, Lewis S, Mandel J, Palevsky HI, Rich S, Sood N, Rosenzweig EB, Trow TK, Yung R, Elliott CG, Badesch DB. Pharmacologic Therapy for Pulmonary Arterial Hypertension in Adults CHEST Guideline and Expert Panel Report. CHEST Journal 2014, 146: 449-475. PMID: 24937180, PMCID: PMC4137591, DOI: 10.1378/chest.14-0793.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntihypertensive AgentsConsensusDelphi TechniqueFamilial Primary Pulmonary HypertensionHumansHypertension, PulmonaryPractice Guidelines as TopicConceptsPulmonary arterial hypertensionHigh-level evidenceConsensus statementPharmacologic therapyAvailable evidenceArterial hypertensionGrades of RecommendationCochrane Library databasesExpert Panel ReportClinician adviceOptimal pharmacotherapyAdult patientsCHEST GuidelineGuideline recommendationsHigh-level recommendationsClinical questionsLibrary databasesSystematic reviewClinical decisionPharmacotherapyTherapyHypertensionEnglish-language evidenceLevel evidenceFurther studies
2013
Preface
Trow TK. Preface. Clinics In Chest Medicine 2013, 34: xiii-xiv. PMID: 24267311, DOI: 10.1016/j.ccm.2013.10.009.Peer-Reviewed Original ResearchDiagnosis of Pulmonary Arterial Hypertension
Forfia PR, Trow TK. Diagnosis of Pulmonary Arterial Hypertension. Clinics In Chest Medicine 2013, 34: 665-681. PMID: 24267297, DOI: 10.1016/j.ccm.2013.09.001.Peer-Reviewed Original ResearchMeSH KeywordsCardiac CatheterizationEchocardiographyElectrocardiographyFamilial Primary Pulmonary HypertensionHumansHypertension, PulmonaryPhysical ExaminationRadiography, ThoracicConceptsPulmonary arterial hypertensionArterial hypertensionPulmonary venous hypertensionPopulation of patientsEchocardiographic cluesNonpharmacologic managementPulmonary hypertensionRight shuntingVenous hypertensionCardiac catheterizationClinical suspicionRight heartNoninvasive testsPhysical examLeft heartHigh indexHypertensionAccurate diagnosisDiagnosisCareful assessmentCatheterizationHeartPatientsShuntingSuspicionStandard Nonspecific Therapies in the Management of Pulmonary Arterial Hypertension
Sauler M, Fares WH, Trow TK. Standard Nonspecific Therapies in the Management of Pulmonary Arterial Hypertension. Clinics In Chest Medicine 2013, 34: 799-810. PMID: 24267305, DOI: 10.1016/j.ccm.2013.08.013.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsCalcium Channel BlockersDigoxinDiureticsFamilial Primary Pulmonary HypertensionHumansHypertension, PulmonaryOxygen Inhalation TherapyConceptsHigh-dose calcium channel blockersCommon cardiopulmonary diseasesPAH-specific therapyPulmonary arterial hypertensionTreatment of patientsCalcium channel blockersPAH therapyArterial hypertensionAdjunct therapyOxygen therapyMedical therapyNonspecific therapyCardiopulmonary diseasePathologic understandingChannel blockersSmall studyTherapyHypertension researchExpert opinionAnticoagulationHypertensionDiureticsPatientsBlockersDigoxin
2012
IL-13 receptor α2-arginase 2 pathway mediates IL-13-induced pulmonary hypertension
Cho WK, Lee CM, Kang MJ, Huang Y, Giordano FJ, Lee PJ, Trow TK, Homer RJ, Sessa WC, Elias JA, Lee CG. IL-13 receptor α2-arginase 2 pathway mediates IL-13-induced pulmonary hypertension. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2012, 304: l112-l124. PMID: 23125252, PMCID: PMC3543640, DOI: 10.1152/ajplung.00101.2012.Peer-Reviewed Original ResearchConceptsPulmonary hypertensionIL-13Human pulmonary artery smooth muscle cellsDevelopment of PHPulmonary artery smooth muscle cellsRight ventricle systolic pressurePathogenesis of PHArtery smooth muscle cellsExpression of ARG2Pulmonary arterial hypertensionPulmonary vascular remodelingVentricle systolic pressurePotential therapeutic targetIL-13 treatmentSmooth muscle cellsNull mutant miceArterial hypertensionEffector cytokinesMedial thickeningSystolic pressureHemodynamic changesPulmonary arterySmall-interfering RNAVascular remodelingArginase-2Targeted approaches to the treatment of pulmonary hypertension
Fares WH, Trow TK. Targeted approaches to the treatment of pulmonary hypertension. Therapeutic Advances In Respiratory Disease 2012, 6: 147-159. PMID: 22438264, DOI: 10.1177/1753465812441849.Peer-Reviewed Original ResearchConceptsPulmonary arterial hypertensionArterial hypertensionHigh-dose calcium channel blockersChest Physicians criteriaMultiple therapeutic optionsDurability of responseCalcium channel blockersTransplant evaluationPulmonary hypertensionOral therapyClose followPhysician's criteriaTherapeutic optionsChannel blockersEarly initiationAmerican CollegeHigh riskPatientsIncurable diseaseHypertensionEarly useStatus benefitsTreatmentDiseaseProgression
2011
Pregnancy and Pulmonary Hypertension
Lane CR, Trow TK. Pregnancy and Pulmonary Hypertension. Clinics In Chest Medicine 2011, 32: 165-174. PMID: 21277457, DOI: 10.1016/j.ccm.2010.10.006.Peer-Reviewed Original ResearchMeSH KeywordsDelivery, ObstetricDirective CounselingFemaleHumansHypertension, PulmonaryMaternal MortalityPregnancyPregnancy ComplicationsPregnancy Outcome
2010
A 71-Year-Old Woman With Myelofibrosis, Hypoxemia, and Pulmonary Hypertension
Trow TK, Argento AC, Rubinowitz AN, Decker R. A 71-Year-Old Woman With Myelofibrosis, Hypoxemia, and Pulmonary Hypertension. CHEST Journal 2010, 138: 1506-1510. PMID: 21138888, DOI: 10.1378/chest.10-0973.Peer-Reviewed Original ResearchAgedAntimonyBiopsy, NeedleBlood Chemical AnalysisCardiac CatheterizationDiagnosis, DifferentialDyspneaFemaleHematopoiesis, ExtramedullaryHumansHypertension, PulmonaryHypoxiaImmunohistochemistryLung DiseasesPhysical ExaminationPrimary MyelofibrosisRadionuclide ImagingRare DiseasesRespiratory Function TestsTechnetium CompoundsTomography, X-Ray ComputedChronic Thromboembolic Pulmonary Hypertension
Auger WR, Kim NH, Trow TK. Chronic Thromboembolic Pulmonary Hypertension. Clinics In Chest Medicine 2010, 31: 741-758. PMID: 21047580, DOI: 10.1016/j.ccm.2010.07.006.Peer-Reviewed Original ResearchMeSH KeywordsChronic DiseaseEndarterectomyHumansHypertension, PulmonaryIncidencePulmonary EmbolismRisk FactorsVenous ThromboembolismConceptsChronic thromboembolic pulmonary hypertensionThromboembolic pulmonary hypertensionPulmonary hypertensionSpecific medical therapySmall vessel arteriopathyMedical therapyPreoperative evaluationMechanical obstructionPulmonary vasculatureAcute embolusRisk factorsHypertensionPatientsNatural historyPutative mechanismsLimited dataSole causeArteriopathyEndartectomyEmboliObstructionTherapyNoncandidatesEpidemiologyDiagnosis
2009
Endothelin receptor blockade in the management of pulmonary arterial hypertension: Selective and dual antagonism
Trow TK, Taichman DB. Endothelin receptor blockade in the management of pulmonary arterial hypertension: Selective and dual antagonism. Respiratory Medicine 2009, 103: 951-962. PMID: 19304472, DOI: 10.1016/j.rmed.2009.02.016.Peer-Reviewed Original ResearchConceptsPulmonary arterial hypertensionEndothelin receptor antagonistsArterial hypertensionET-1Development of PAHManagement of PAHPathogenesis of PAHEndothelin receptor blockadeLiver function abnormalitiesPlacebo-controlled trialNitric oxide-mediated pathwayClinical study resultsGood clinical resultsClinical treatment studiesUnited States FoodPeripheral edemaFunction abnormalitiesReceptor blockadeDual antagonismDual blockadeSafety profileET receptorsEndothelin-1Head studiesReceptor antagonist
2008
Pulmonary Hypertension After Surgical Laminectomy: An Easily Missed Cause of a High-Output State
Curran DR, Trow TK, Muhs B, Sergi M. Pulmonary Hypertension After Surgical Laminectomy: An Easily Missed Cause of a High-Output State. The American Journal Of Medicine 2008, 121: e3-e4. PMID: 18691468, DOI: 10.1016/j.amjmed.2008.03.044.Peer-Reviewed Original Research
2005
Clinical Year in Review I
Trow TK. Clinical Year in Review I. Annals Of The American Thoracic Society 2005, 2: 102-104. PMID: 16113476, DOI: 10.1513/pats.200506-057tt.Peer-Reviewed Original Research