Featured Publications
The Combined Effects of Frailty and Cognitive Impairment on Post-ICU Disability among Older ICU Survivors
Ferrante LE, Murphy TE, Leo-Summers LS, Gahbauer EA, Pisani MA, Gill TM. The Combined Effects of Frailty and Cognitive Impairment on Post-ICU Disability among Older ICU Survivors. American Journal Of Respiratory And Critical Care Medicine 2019, 200: 107-110. PMID: 30883191, PMCID: PMC6603056, DOI: 10.1164/rccm.201806-1144le.Peer-Reviewed Original ResearchThe Association of Frailty With Post-ICU Disability, Nursing Home Admission, and Mortality A Longitudinal Study
Ferrante LE, Pisani MA, Murphy TE, Gahbauer EA, Leo-Summers LS, Gill TM. The Association of Frailty With Post-ICU Disability, Nursing Home Admission, and Mortality A Longitudinal Study. CHEST Journal 2018, 153: 1378-1386. PMID: 29559308, PMCID: PMC6026287, DOI: 10.1016/j.chest.2018.03.007.Peer-Reviewed Original ResearchConceptsNursing home admissionPost-ICU disabilityHome admissionCritical illnessFrailty statusGreater disabilityNew nursing home admissionsAssociation of frailtyLikelihood of deathOne-point increaseICU admissionICU survivorsICU outcomesMean agePrognostic informationPrefrailtyFried indexAdmissionFrailtyOlder personsParent cohortAnalytic sampleFunctional activityNonfrailtyDisabilityFrailty is crucial in FORECASTing outcomes in critical care
Ferrante L, Szczeklik W. Frailty is crucial in FORECASTing outcomes in critical care. Intensive Care Medicine 2024, 50: 1119-1122. PMID: 38953928, PMCID: PMC11556853, DOI: 10.1007/s00134-024-07518-0.Commentaries, Editorials and Letters
2023
What is Frailty?
Brighton L, Lareau S, Maddocks M, Osadnik C, Lahousse L, Lee A, Allison J, Singer J, Rozenberg D, Man W, Ferrante L, Spruit M, Burtin C, Harrison S, Iyer A. What is Frailty? American Journal Of Respiratory And Critical Care Medicine 2023, 207: p5-p6. PMID: 37260228, PMCID: PMC10263127, DOI: 10.1164/rccm.207i11p5.Peer-Reviewed Educational MaterialsRehabilitation for People with Respiratory Disease and Frailty: An Official American Thoracic Society Workshop Report
Maddocks M, Brighton L, Alison J, Beek L, Bhatt S, Brummel N, Burtin C, Cesari M, Evans R, Ferrante L, Flores-Flores O, Franssen F, Garvey C, Harrison S, Iyer A, Lahouse L, Lareau S, Lee A, Man W, Marengoni A, McAuley H, Rozenberg D, Singer J, Spruit M, Osadnik C. Rehabilitation for People with Respiratory Disease and Frailty: An Official American Thoracic Society Workshop Report. Annals Of The American Thoracic Society 2023, 20: 767-780. PMID: 37261787, PMCID: PMC10257033, DOI: 10.1513/annalsats.202302-129st.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsRespiratory diseasePulmonary rehabilitationOfficial American Thoracic Society Workshop ReportHome-based pulmonary rehabilitationAmerican Thoracic Society workshopPalliative care expertiseIdentification of frailtyChronic respiratory diseasesRole of rehabilitationWorse health outcomesOnward referralSymptom burdenExercise prescriptionSpecialist inputCare expertiseHealth outcomesFrailtyDiseaseAvailable evidenceRehabilitationOutcomesBasis of sensitivityWorkshop reportComprehensive assessmentComorbiditiesBetter but Not Well: Disability, Frailty, and Cognitive Impairment One Year after COVID-19 Critical Illness
Auriemma C, Ferrante L. Better but Not Well: Disability, Frailty, and Cognitive Impairment One Year after COVID-19 Critical Illness. Annals Of The American Thoracic Society 2023, 20: 202-203. PMID: 36723478, PMCID: PMC9989858, DOI: 10.1513/annalsats.202211-929ed.Commentaries, Editorials and Letters
2022
Long-term recovery after critical illness in older adults
Kaushik R, Ferrante LE. Long-term recovery after critical illness in older adults. Current Opinion In Critical Care 2022, 28: 572-580. PMID: 35950731, PMCID: PMC9458622, DOI: 10.1097/mcc.0000000000000981.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOlder ICU patientsPost-ICU recoveryCritical illnessGeriatric syndromesLong-term recoveryOlder adultsICU patientsRisk factorsIncidence of frailtyOlder ICU survivorsTransitional care programLong-term outcomesContinuum of careSocial isolationRecent epidemiologic workSocial risk factorsICU survivorsRecent literature pertainingUnique needsRecent longitudinal studiesNew disabilityWorse outcomesFunctional declineCare programSyndromeTrends in Geriatric Conditions Among Older Adults Admitted to US ICUs Between 1998 and 2015
Cobert J, Jeon SY, Boscardin J, Chapman AC, Ferrante LE, Lee S, Smith AK. Trends in Geriatric Conditions Among Older Adults Admitted to US ICUs Between 1998 and 2015. CHEST Journal 2022, 161: 1555-1565. PMID: 35026299, PMCID: PMC9248079, DOI: 10.1016/j.chest.2021.12.658.Peer-Reviewed Original ResearchConceptsICU admissionPre-existing disabilityGeriatric conditionsOlder adultsSelf-reported chronic diseasesPatients 65 yearsRate of dementiaICU patientsAdverse outcomesICU settingChronic diseasesAdjusted proportionDaily livingMultimorbidityICUAdmissionGeriatric principlesFrailtyDementiaUS ICUsFunctional measuresStudy designDisabilityAdultsTime trends
2020
Frailty in Critical Care Medicine: A Review.
De Biasio JC, Mittel AM, Mueller AL, Ferrante LE, Kim DH, Shaefi S. Frailty in Critical Care Medicine: A Review. Anesthesia & Analgesia 2020, 130: 1462-1473. PMID: 32384336, PMCID: PMC7426653, DOI: 10.1213/ane.0000000000004665.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsFrailty syndromeCare settingsDetermination of frailtyIntensive care patientsIntensive care unitHealth care utilizationAcute care settingCritical care settingClinical risk assessmentFrailty measurement toolsCritical care medicineAge-related accumulationCare patientsFrailty measurementRisk stratificationCare unitCare utilizationClinical entityPoor outcomePoor responsePrognostic trendObservational studyFunctional declineCare medicineMultisystem dysregulation
2019
Frailty assessment in the ICU: translation to ‘real‐world' clinical practice
Falvey JR, Ferrante LE. Frailty assessment in the ICU: translation to ‘real‐world' clinical practice. Anaesthesia 2019, 74: 700-703. PMID: 30859547, PMCID: PMC6521947, DOI: 10.1111/anae.14617.Commentaries, Editorials and Letters
2018
The Competing Risk of Death in Longitudinal Geriatric Outcomes
Murphy TE, Gill TM, Leo‐Summers L, Gahbauer EA, Pisani MA, Ferrante LE. The Competing Risk of Death in Longitudinal Geriatric Outcomes. Journal Of The American Geriatrics Society 2018, 67: 357-362. PMID: 30537050, PMCID: PMC6367003, DOI: 10.1111/jgs.15697.Peer-Reviewed Original ResearchConceptsFall-related hospitalizationsRisk of deathProspective cohort studyPersons 70 yearsLong-term followPrecipitating Events ProjectCommunity-based dataLongitudinal studyGeriatric outcomesCohort studyFried phenotypeFunctional recoveryTotal disabilityOutcome eventsDaily livingClinical scenariosSecondary analysisOlder personsVision impairmentDeathBasic activitiesOutcomesDisabilityDecedentsRisk