2015
Personalized Critical Care Medicine: How Far Away Are We?
Ahasic AM, Christiani DC. Personalized Critical Care Medicine: How Far Away Are We? Seminars In Respiratory And Critical Care Medicine 2015, 36: 809-822. PMID: 26595041, DOI: 10.1055/s-0035-1564852.Peer-Reviewed Original ResearchConceptsCritical illnessClinical trialsAcute respiratory distress syndromeRespiratory distress syndromeIntensive care unitCritical care arenaDirect patient careUnique risk factorsMulti-biomarker panelAccurate diagnostic classificationMajor clinical applicationsPrecise medical careDistress syndromeCare unitPoor outcomeRisk factorsTreatment decisionsIndividual patientsClinical careClinical utilitySuch biomarkersMedical carePatient careClinical useIllness
2011
IGF1 and IGFBP3 in acute respiratory distress syndrome
Ahasic AM, Zhai R, Su L, Zhao Y, Aronis KN, Thompson BT, Mantzoros CS, Christiani DC. IGF1 and IGFBP3 in acute respiratory distress syndrome. European Journal Of Endocrinology 2011, 166: 121-129. PMID: 22004906, PMCID: PMC3757506, DOI: 10.1530/eje-11-0778.Peer-Reviewed Original ResearchConceptsAcute respiratory distress syndromeLevels of IGF1Development of ARDSRespiratory distress syndromeIGFBP3 levelsARDS casesDistress syndromePersistent acute respiratory distress syndromeFibrotic lung diseaseSeverity of illnessIntensive care unitCase-cohort studyRelevant clinical covariatesCause mortalityConsecutive patientsCare unitLung diseaseRisk factorsClinical covariatesPlasma IGF1Parent studyCase statusPatientsIGF pathwayDay 60