Pro/Con debate: is occupational asthma induced by isocyanates an immunoglobulin E‐mediated disease?
Wisnewski AV, Jones M. Pro/Con debate: is occupational asthma induced by isocyanates an immunoglobulin E‐mediated disease? Clinical & Experimental Allergy 2010, 40: 1155-1162. PMID: 20545707, PMCID: PMC3121887, DOI: 10.1111/j.1365-2222.2010.03550.x.Peer-Reviewed Original ResearchConceptsAllergen-specific IgEOccupational asthmaIsocyanate asthmaPro/Con DebateScreening/surveillanceCause of asthmaIgE-mediated diseasesHypersensitive individualsLow molecular weight chemicalsEnvironmental AsthmaAllergic asthmaBronchial hyperreactivityHypersensitivity disordersCommon causeAsthmaPathogenic mechanismsIgEChronic exposureCon debateImportant mediatorDiagnostic testsWeight chemicalsDiseaseHypersensitivityPrevention