2020
Analysis of Lung Gene Expression Reveals a Role for Cl- channels in Diisocyanate Induced Airway Eosinophilia in a Mouse Model of Asthma Pathology
Wisnewski AV, Liu J, Redlich CA. Analysis of Lung Gene Expression Reveals a Role for Cl- channels in Diisocyanate Induced Airway Eosinophilia in a Mouse Model of Asthma Pathology. American Journal Of Respiratory Cell And Molecular Biology 2020, 0: 25-35. PMID: 32101465, PMCID: PMC7328250, DOI: 10.1165/rcmb.2019-0400oc.Peer-Reviewed Original ResearchConceptsRespiratory tract exposureAirway eosinophiliaMonocytes/macrophagesMouse modelGene expressionGene transcriptsBiological pathwaysAsthma pathologyUpregulated gene transcriptsIgE-independent mechanismsLung gene expressionLung tissue gene expressionCause of asthmaBALB/cTransgenic B cellsTissue gene expressionExpression changesDiisocyanate asthmaSensitized workersAsthma pathogenesisAirway fluidDeficient miceMRNA microarrayEosinophiliaB cells
1999
A Human Anti-HIV Autoantibody Enhances EBV Transformation and HIV Infection
Cavacini L, Wisnewski A, Peterson J, Montefiori D, Emes C, Duval M, Kingsbury G, Wang A, Scadden D, Posner M. A Human Anti-HIV Autoantibody Enhances EBV Transformation and HIV Infection. Clinical Immunology 1999, 93: 263-273. PMID: 10600338, DOI: 10.1006/clim.1999.4790.Peer-Reviewed Original ResearchConceptsUninfected lymphoid cellsLymphoid cellsEBV transformationB cellsHIV-1-infected cellsHIV-1 infectionComplement-dependent mannerCross-reactive natureB cell proliferationNormal B cellsHIV infectionHIV pathogenesisNK cellsAntibody responseFree gp120Immunoglobulin productionT cellsHIV-1Human mAbsViral infectionVH3 family genesIgG mAbsHuman IgG mAbsUninfected cellsInfection