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Petr Protiva, MD, MPH

Associate Professor of Medicine (Digestive Diseases); Adjunct Faculty at Breslow Lab, Rockefeller University, New York, NY

Contact Information

Petr Protiva, MD, MPH

Patient Care Locations

Mailing Address

  • Yale School of Medicine

    Department of Medicine (Digestive Diseases), PO Box 208019

    New Haven, CT 06520-8019

    United States



Dr Protiva is a clinician scientist with focus on colon cancer biology, screening and prevention. Main goal of his research is to identify the biological pathways and interventions that modulate the risk of cancer with special focus on colon cancer and nutrition. His laboratory focuses on cancer prevention and investigates the molecular events underlying preventive interventions using translational approach in a highly controlled settings. His group elucidated molecular events underlying the effects of estrogen, folic acid, vitamin D, calcium and Western style diet in human colorectal tissue.

Dr Protiva’s additional cancer research project involve clinical research. He serves as a local site investigator for the largest interventional VA study – CSP#577 – investigating the effect of colonoscopy vs FIT on mortality from colon cancer (50,000 subjects randomized).

In addition, Dr Protiva conducts epidemiology research using healthcare databases, exploring large patient datasets and generating hypotheses for future cancer research.

Other focus of his laboratory is the analysis and systems approach to basic and translational research questions using genome wide gene expression analysis. He collaborates with other researchers that show overlap with his interest in colon cancer biology or interpretation of large-scale gene expression data.

He serves as an Associate Editor for the BMJ Open Gastroenterology where he manages manuscripts related to luminal GI research.

Education & Training

  • MPH
    Yale University, Applied Biostatistics and Epidemiology (2017)
  • Research Associate
    Rockefeller University, New York, NY (2006)
  • MD
    Charles University (1993)
  • BA
    Masaryk University (1987)


  • Board Certification
    AB of Internal Medicine, Gastroenterology (2003, recertified: 2023)

Professional Service

AGAObesity and microbiome research Meetings organizer, proposed topics and moderate session2019 - 2021

Departments & Organizations