Emma Kruglov
Research Associate Internal Medicine Digestive DiseaseCards
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About
Titles
Research Associate Internal Medicine Digestive Disease
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Emma Kruglov's published research.
Publications Timeline
A big-picture view of Emma Kruglov's research output by year.
Barbara Ehrlich, PhD
David A. Hafler, MD, FANA
Joao Pereira, PhD
Mateus Guerra, PhD
Michael Mak
Michael H Nathanson, MD, PhD
2Publications
Publications
Neutrophils insert elastase into hepatocytes to regulate calcium signaling in alcohol-associated hepatitis
Ogino N, Leite M, Guerra M, Kruglov E, Asashima H, Hafler D, Ito T, Pereira J, Peiffer B, Sun Z, Ehrlich B, Nathanson M. Neutrophils insert elastase into hepatocytes to regulate calcium signaling in alcohol-associated hepatitis. Journal Of Clinical Investigation 2024 PMID: 38916955, DOI: 10.1172/jci171691.Peer-Reviewed Original ResearchAltmetricConceptsAlcohol-associated hepatitisReduced cell proliferationCalcium channel expressionCalcium signaling mechanismsIntracellular calcium channelsCell proliferationRegulate calcium signalingNeutrophil extracellular trapsChannel expressionNeutrophil granule proteinsCalcium channelsNeutrophil infiltrationPatient specimensGranule proteasesMouse modelHealthy subjectsLiver diseaseExtracellular trapsCalcium signalingSerpin E2NeutrophilsElastase activityHepatitisTissue remodelingSignaling mechanismsAdaptation to mechanical stresses drives an apoptosis-resistant and invasive phenotype in liver cells
Gong X, Ogino N, de Fátima Leite M, Chen Z, Nguyen R, Liu R, Kruglov E, Flores K, Cabral A, de M. Mendes G, Ehrlich B, Mak M. Adaptation to mechanical stresses drives an apoptosis-resistant and invasive phenotype in liver cells. Biophysical Journal 2024, 123: 177a. DOI: 10.1016/j.bpj.2023.11.1163.Peer-Reviewed Original Research