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Identification of Subclinical Acute Interstitial Nephritis


Acute interstitial nephritis (AIN) is a common condition characterized by minimal clinical features and slowly worsening kidney function. As a result, by the time AIN is diagnosed, permanent kidney damage has already occurred. Early recognition of AIN could prevent the occurrence of permanent kidney damage. To identify patients with AIN in a timely manner, we will set up screening algorithms in the electronic health record. We will then evaluate patients identified through this algorithm with novel biomarkers.

Contact Information

For more information, or if you are interested in collaborating on this study, please contact Dr. Dennis Moledina

Project Funding

Funding for this project comes, in part, from the following grant:

P30 DK079310 (NIH/NIDDK)
“George M. O'Brien Kidney Center at Yale”



Chirag R. Parikh, MD, PhD
Adjunct Professor of Medicine, Nephrology, Yale University

Mark A. Perazella, MD
Professor of Medicine, Nephrology, Yale University

F. Perry Wilson, MD, MSCE
Assistant Professor of Medicine, Nephrology, Yale University