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Arya Mani

Robert W Berliner Professor of Internal Medicine (Cardiology) and Professor of Genetics; Director, Cardiovascular Genetics Program; Director, Cardiovascular Module

Contact Information

Arya Mani, MD, FACC, FAHA

Patient Care Locations

Lab Location

  • 300 George Street, Ste 759
    New Haven, CT 06511

Mailing Address

  • Cardiovascular Medicine

    PO Box 208056, 333 Cedar Street

    New Haven, CT 06520-8056

    United States



Dr. Mani received his M.D. from Johannes Gutenberg University in 1991 in Germany where he had begun his scientific studies in cancer research. Later that year, he arrived at Yale and worked with Dr. Fred Gorelick on pancreatic exocrine diseases in the Department of Cell Biology and Gastroenterology prior to starting his Internal Medicine residency training at Yale New Haven Hospital, which he completed in 1996 after which he was chosen as chief resident. He then pursued a cardiovascular clinical fellowship at Yale along with post-doctoral studies in the Department of Genetics under Dr. Richard Lifton, where he began his focused work on human cardiovascular genetics. He joined the faculty in the Department of Internal Medicine, Section of Cardiovascular Medicine, initially as an instructor. He was appointed to assistant professor in 2002 and promoted to professor of medicine and genetics in 2016.

Dr. Mani has published his research findings in leading journals such as Science, NEJM, Cell Metab, PNAS, Nature Genetics, and others. Due to these and other scientific accomplishments, he has been invited to speak globally and has been recognized with multiple fellowships and awards, including the highly coveted NIH Outstanding Investigator Award in 2017.

Education & Training

  • Fellow
    Yale University School of Medicine (2001)
  • Chief Resident
    Yale University (1997)
  • Resident
    Yale-New Haven Hospital (1996)
  • Fellow
    University of Erlangen-Nuernberg (1992)
  • MD
    Johannes-Gutenberg-University of Mainz (1991)


  • The genetic etiology of coronary artery disease
    Mumbai, MH, India 2001
    Identification of genetic causes of premature coronary artery disease in South Asians
  • Genetics of Cardiovascular Diseases
    Isfahan, Iran; Shiraz, Fars, Iran; Tehran, Tehran, Iran 1998
    Study of genetic causes of coronary artery disease and congenital heart defect

Honors & Recognition

AwardAwarding OrganizationDate
NIH Outstanding Investigator Award 2017NIH2022
Doris Duke Clinical Scientist Development Awards 2008Doris Duke2022
The Interurban Clinical Club Sir William Osler Young Investigator Award2007
Howard Hughes Fellowship AwardHoward Hughes Medical Institute2001

Departments & Organizations