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Jason Jonathon Sico

Associate Professor of Neurology; Associate Professor Internal Medicine (Section of General Medicine), Internal Medicine; Director, Stroke Care VA Connecticut Healthcare System; Director of Research and Clinical Care, Headache Center of Excellence, Neurology

Research Summary

As a health services research and implementation scientist, my research falls under two domains: improving post-ischemic stroke vascular risk factor management and investigating how medical comorbidities among ischemic stroke patients may be both novel stroke risk factors and adversely affect outcomes (e.g., mortality and readmission rates). Several areas that I am actively examining include: the use implementation science strategies and Lean Six Sigma approaches to improve the delivery of guideline-concordant post-stroke vascular risk factor management, understanding the culture of communication and collaboration between neurologists and primary care providers in post-stroke care, identifying barriers and facilitators to the delivery of high-quality stroke care, the role of HIV and stroke risk in the era of combined anti-retroviral therapy, hematologic abnormalities associated with higher mortality rates among stroke patients, and addressing cardiac screening in this high risk vascular population.

Specialized Terms: Ischemic stroke; Implementation Science; Lean Six Sigma/Systems Redesign; Health services research; Outcomes based research; Vascular Risk Factor Management; Obstructive sleep apnea; HIV/AIDS; Neuropathy

Extensive Research Description

  • Health Services Research
  • Implementation Science
  • Improving Post-Stroke Vascular Risk Factor Control
  • Hypertension Control and Management
  • Screening for and Testing Obstructive Sleep Apnea among Stroke Survivors
  • Medical comorbidities and their influence on stroke outcome
  • Use of Systems Redesign/Health Systems Engineering in Stroke Care
  • Pragmatic Trials
  • Organizational and Provider-level Interventions
  • HIV and Ischemic Stroke in the era of combined antiretroviral therapy
  • HIV Neuropathy
  • Neurological Disease among Veterans and Active Military Personnel
  • Headache Care
  • Pain
  • Demonstrating the Value of Neurologists among Patients with Neurological Conditions
  • Care Collaboration between Specialists and Generalists
  • Burnout among Neurologists


Research Interests

Acquired Immunodeficiency Syndrome; Burnout, Professional; Headache; Health Services Research; Hematologic Diseases; HIV; Mortality; Neurology; Organizational Innovation; Patient Readmission; Veterans; Global Health; Sleep Apnea, Obstructive; Stroke; Qualitative Research

Selected Publications