Ling Han
Research & Publications
Biography
News
Research Summary
Dr. Han's research career started with psychiatric epidemiology and clinical psychometry three decades ago, when he was a practicing psychiatrist and lecturer in a university affiliated teaching hospital in Nanjing, China. He published a series of reports on prevalence and risk factors of neurotic disorders and won 2 WHO awards for Chinese Young Professionals and The SHANGHAI-RHONE-POULENC Award for Outstanding Research Paper. In 1994, he came to the University of Washington Department of Psychiatry and Behavioral Medicine as an International Medical Scholar Program fellow under ECFMG’s sponsorship. Afterwards he worked as a NIH Visiting Associate with NIMH and published the first epidemiological survey on mood seasonality in Chinese population. Subsequently he completed a research fellowship in geriatric psychiatry with McGill University, where he developed a clinician consensus-based anticholinergic score to assess cognitive burden of anticholinergic medications. After joining Yale Program on Aging (POA) in 2001, his research interests had since expanded to longitudinal modeling of cognitive and functional decline and quasi-experimental methodologies to address selection and confounding bias in observational studies. In collaboration with POA and VA colleagues, he updated the clinician-rated anticholinergic score to assess a broader array of common medications used in elderly and raised awareness of medical and general communities to potential chronic effects of anticholinergic polypharmacy on cognitive and executive functions of community-dwelling older persons. His other areas of active research include application of latent class growth model to “phenotype” cognitive and functional aging, and use of propensity score and other quasi-experimental methodologies to address potential selection and indication bias in observational studies of medical interventions, including opioid medications and complementary and integrative approaches for chronic pain. Recently his research interests have extended to the use of multi-level mixed effect model to delineate potential “contextual” effects of healthcare facilities and socioeconomic environments on diseases and health outcomes and their interactions with individual risk factors of patients.
Coauthors
Research Interests
Activities of Daily Living; Alzheimer Disease; Chronic Disease; Cognition Disorders; Delirium; Depressive Disorder; Pain
Public Health Interests
Aging; Epidemiology Methods; Health Care Quality, Efficiency; Mental Health; Modeling
Selected Publications
- Dissemination and implementation of age‐friendly care and geriatric emergency department accreditation at Veterans Affairs hospitalsHwang U, Runels T, Han L, Gruber E, McQuown C, Ragsdale L, Jetter E, Rossomano N, Javier D. Dissemination and implementation of age‐friendly care and geriatric emergency department accreditation at Veterans Affairs hospitals Academic Emergency Medicine 2023 PMID: 36653961, DOI: 10.1111/acem.14665.
- USE OF COMPLEMENTARY HEALTH APPROACHES AND PRESCRIPTION OPIOIDS AMONG VETERANS WITH MUSCULOSKELETAL DISORDERSHan L, Goulet J, Skanderson M, Redd D, Brandt C, Zeng Q. USE OF COMPLEMENTARY HEALTH APPROACHES AND PRESCRIPTION OPIOIDS AMONG VETERANS WITH MUSCULOSKELETAL DISORDERS Innovation In Aging 2022, 6: 708-708. DOI: 10.1093/geroni/igac059.2589.
- Post-9/11 deployment history and the incidence of breast cancer among women VeteransGaffey A, Han L, Ramsey C, Skanderson M, Dziura J, Driscoll M, Burg M, Brandt C, Bastian L, Haskell S. Post-9/11 deployment history and the incidence of breast cancer among women Veterans Annals Of Epidemiology 2022, 77: 98-102. PMID: 36470323, DOI: 10.1016/j.annepidem.2022.11.010.
- Characteristics Associated with Spirometry Guideline Adherence in VA Patients Hospitalized with Chronic Obstructive Pulmonary DiseaseRodwin BA, DeRycke EC, Han L, Bade BC, Brandt CA, Bastian LA, Akgün KM. Characteristics Associated with Spirometry Guideline Adherence in VA Patients Hospitalized with Chronic Obstructive Pulmonary Disease Journal Of General Internal Medicine 2022, 38: 619-626. PMID: 36241942, PMCID: PMC9971396, DOI: 10.1007/s11606-022-07826-5.
- Mental Health Diagnoses are Not Associated With Indicators of Lower Quality Pain Care in Electronic Health Records of a National Sample of Veterans Treated in Veterans Health Administration Primary Care SettingsDobscha SK, Luther SL, Kerns RD, Finch DK, Goulet JL, Brandt CA, Skanderson M, Bathulapalli H, Fodeh SJ, Hahm B, Bouayad L, Lee A, Han L. Mental Health Diagnoses are Not Associated With Indicators of Lower Quality Pain Care in Electronic Health Records of a National Sample of Veterans Treated in Veterans Health Administration Primary Care Settings Journal Of Pain 2022, 24: 273-281. PMID: 36167230, PMCID: PMC9898089, DOI: 10.1016/j.jpain.2022.08.009.
- National Cohort Study of Homebound Persons Living With Dementia: Antibiotic Prescribing Trends and Opportunities for Antibiotic StewardshipDatta R, Fried T, O’Leary J, Zullo AR, Allore H, Han L, Juthani-Mehta M, Cohen A. National Cohort Study of Homebound Persons Living With Dementia: Antibiotic Prescribing Trends and Opportunities for Antibiotic Stewardship Open Forum Infectious Diseases 2022, 9: ofac453. PMID: 36147594, PMCID: PMC9487603, DOI: 10.1093/ofid/ofac453.
- Military sexual trauma and incident hypertension: a 16-year cohort study of young and middle-aged men and womenGaffey AE, Rosman L, Sico JJ, Haskell SG, Brandt CA, Bathulapalli H, Han L, Dziura J, Skanderson M, Burg MM. Military sexual trauma and incident hypertension: a 16-year cohort study of young and middle-aged men and women Journal Of Hypertension 2022, 40: 2307-2315. PMID: 35983872, DOI: 10.1097/hjh.0000000000003267.
- Catastrophic health expenditure among Chinese adults living alone with cognitive impairment: findings from the CHARLSLi C, Jin S, Cao X, Han L, Sun N, Allore H, Hoogendijk EO, Xu X, Feng Q, Liu X, Liu Z. Catastrophic health expenditure among Chinese adults living alone with cognitive impairment: findings from the CHARLS BMC Geriatrics 2022, 22: 640. PMID: 35922775, PMCID: PMC9351200, DOI: 10.1186/s12877-022-03341-8.
- Trends in the prevalence of vision impairment among the oldest-old Chinese population from 1998 to 2018.Luo Y, Zhang Q, Han L, Shen Z, Chen Y, Wang K, Huang Z, De Fries CM, Cao G, Su H, Xu H, Chen Z, Ren Z, Hu Y, Xu B. Trends in the prevalence of vision impairment among the oldest-old Chinese population from 1998 to 2018. Journal Of Global Health 2022, 12: 11006. PMID: 35862489, DOI: 10.7189/jogh.12.11006.
- Factors Associated With Days Away From Home in the Year After Major Surgery Among Community-living Older Persons.Gill TM, Becher RD, Murphy TE, Gahbauer EA, Leo-Summers L, Han L. Factors Associated With Days Away From Home in the Year After Major Surgery Among Community-living Older Persons. Annals Of Surgery 2022, Publish Ahead of Print PMID: 35837967, PMCID: PMC9840715, DOI: 10.1097/sla.0000000000005528.
- Geographic Trends in Opioid Overdoses in the US From 1999 to 2020Post LA, Lundberg A, Moss CB, Brandt CA, Quan I, Han L, Mason M. Geographic Trends in Opioid Overdoses in the US From 1999 to 2020 JAMA Network Open 2022, 5: e2223631. PMID: 35900768, PMCID: PMC9335141, DOI: 10.1001/jamanetworkopen.2022.23631.
- Multimorbidity measures differentially predicted mortality among older Chinese adults.Yao SS, Xu HW, Han L, Wang K, Cao GY, Li N, Luo Y, Chen YM, Su HX, Chen ZS, Huang ZT, Hu YH, Xu B. Multimorbidity measures differentially predicted mortality among older Chinese adults. Journal Of Clinical Epidemiology 2022, 146: 97-105. PMID: 35259446, DOI: 10.1016/j.jclinepi.2022.03.002.
- Functional Trajectories and Resilience Among Adults With Advanced Lung CancerPresley CJ, Arrato NA, Shields PG, Carbone DP, Wong ML, Benedict J, Reisinger SA, Han L, Gill TM, Allore H, Andersen BL, Janse S. Functional Trajectories and Resilience Among Adults With Advanced Lung Cancer JTO Clinical And Research Reports 2022, 3: 100334. PMID: 35719868, PMCID: PMC9198463, DOI: 10.1016/j.jtocrr.2022.100334.
- Racial and Rural Disparities in COVID-19 Vaccination Uptake in a National Sample of VeteransBernstein E, DeRycke E, Han L, Bastian L, Bean-Mayberry B, Bade B, Brandt C, Farmer M, Crothers K, Skanderson M, Ruser C, Spelman J, Bazan I, Justice A, Rentsch C, Akgun K. Racial and Rural Disparities in COVID-19 Vaccination Uptake in a National Sample of Veterans 2022, a3695-a3695. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a3695.
- Aggressive End-of-Life Care in the Veterans Health Administration versus Fee-for-Service Medicare among Patients with Advanced Lung CancerPresley CJ, Kaur K, Han L, Soulos PR, Zhu W, Corneau E, O'Leary JR, Chao H, Shamas T, Rose MG, Lorenz KA, Levy CR, Mor V, Gross CP. Aggressive End-of-Life Care in the Veterans Health Administration versus Fee-for-Service Medicare among Patients with Advanced Lung Cancer Journal Of Palliative Medicine 2022, 25: 932-939. PMID: 35363053, PMCID: PMC9360181, DOI: 10.1089/jpm.2021.0436.
- Patterns of cardiometabolic multimorbidity and the risk of depressive symptoms in a longitudinal cohort of middle-aged and older Chinese.Huang ZT, Luo Y, Han L, Wang K, Yao SS, Su HX, Chen S, Cao GY, De Fries CM, Chen ZS, Xu HW, Hu YH, Xu B. Patterns of cardiometabolic multimorbidity and the risk of depressive symptoms in a longitudinal cohort of middle-aged and older Chinese. Journal Of Affective Disorders 2022, 301: 1-7. PMID: 34999125, DOI: 10.1016/j.jad.2022.01.030.
- Self-reported and actigraphic short sleep duration in older adults.Miner B, Stone KL, Zeitzer JM, Han L, Doyle M, Blackwell T, Gill TM, Redeker NS, Hajduk A, Yaggi H. Self-reported and actigraphic short sleep duration in older adults. Journal Of Clinical Sleep Medicine 2022, 18: 403-413. PMID: 34338629, PMCID: PMC8804982, DOI: 10.5664/jcsm.9584.
- Risk Factors Associated with Healthcare Utilization for Spine PainHiggins DM, Han L, Kerns RD, Driscoll MA, Heapy AA, Skanderson M, Lisi AJ, Mattocks KM, Brandt C, Haskell SG. Risk Factors Associated with Healthcare Utilization for Spine Pain Pain Medicine 2022, 23: pnab351. PMID: 34999899, DOI: 10.1093/pm/pnab351.
- Complementary and Integrative Health Approaches and Opioid Prescriptions Among Older Veterans With Chronic PainHan L, Goulet J, Skanderson M, Redd D, Brandt C, Zeng Q. Complementary and Integrative Health Approaches and Opioid Prescriptions Among Older Veterans With Chronic Pain Innovation In Aging 2021, 5: 940-941. PMCID: PMC8682234, DOI: 10.1093/geroni/igab046.3370.
- Development of an ADL-practice guideline: The next step towards guidance in essential nursing care activitiesHan L, Goulet J, Skanderson M, Redd D, Brandt C, Zeng Q. Development of an ADL-practice guideline: The next step towards guidance in essential nursing care activities Innovation In Aging 2021, 5: 942-942. PMCID: PMC8682200, DOI: 10.1093/geroni/igab046.3375.
- Vision impairment, vision correction, and cognitive decline among middle-aged and older Chinese: results from the China health and retirement longitudinal study.Cao GY, Yao SS, Wang K, Han L, Chen ZS, Huang ZT, Zhang Q, Wang C, Hu YH, Xu B. Vision impairment, vision correction, and cognitive decline among middle-aged and older Chinese: results from the China health and retirement longitudinal study. Aging & Mental Health 2021, 25: 2028-2035. PMID: 33063527, DOI: 10.1080/13607863.2020.1828271.
- Visual trajectories and risk of physical and cognitive impairment among older Chinese adults.Cao G, Wang K, Han L, Zhang Q, Yao S, Chen Z, Huang Z, Luo Y, Hu Y, Xu B. Visual trajectories and risk of physical and cognitive impairment among older Chinese adults. Journal Of The American Geriatrics Society 2021, 69: 2877-2887. PMID: 34111310, DOI: 10.1111/jgs.17311.
- Association Between Neighborhood Disadvantage and Functional Well-being in Community-Living Older PersonsGill TM, Zang EX, Murphy TE, Leo-Summers L, Gahbauer EA, Festa N, Falvey JR, Han L. Association Between Neighborhood Disadvantage and Functional Well-being in Community-Living Older Persons JAMA Internal Medicine 2021, 181: 1297-1304. PMID: 34424276, PMCID: PMC8383163, DOI: 10.1001/jamainternmed.2021.4260.
- Measuring pain care quality in the Veterans Health Administration primary care settingLuther SL, Finch DK, Bouayad L, McCart J, Han L, Dobscha SK, Skanderson M, Fodeh SJ, Hahm B, Lee A, Goulet JL, Brandt CA, Kerns RD. Measuring pain care quality in the Veterans Health Administration primary care setting Pain 2021, 163: e715-e724. PMID: 34724683, PMCID: PMC8920945, DOI: 10.1097/j.pain.0000000000002477.
- Sex Differences in Use of a Clinical Complexity Measure to Predict Primary Care UtilizationHaskell SG, Han L, Abel EA, Bastian L, Driscoll M, Dziura J, Burg MM, Skanderson M, Brandt CA. Sex Differences in Use of a Clinical Complexity Measure to Predict Primary Care Utilization Journal Of Women's Health 2021, 31: 71-78. PMID: 34388023, DOI: 10.1089/jwh.2021.0103.
- Association Between Potentially Inappropriate Medications and 30-Day Post–Hospital Discharge Outcomes in US VeteransAllore HG, Gnjidic D, Skanderson M, Han L. Association Between Potentially Inappropriate Medications and 30-Day Post–Hospital Discharge Outcomes in US Veterans Annals Of Pharmacotherapy 2021, 56: 256-263. PMID: 34282638, PMCID: PMC8770754, DOI: 10.1177/10600280211032072.
- Functional Disability Among Older Versus Younger Adults With Advanced Non-Small-Cell Lung Cancer.Presley CJ, Arrato NA, Janse S, Shields PG, Carbone DP, Wong ML, Han L, Gill TM, Allore HG, Andersen BL. Functional Disability Among Older Versus Younger Adults With Advanced Non-Small-Cell Lung Cancer. JCO Oncology Practice 2021, 17: e848-e858. PMID: 33939536, PMCID: PMC8258136, DOI: 10.1200/op.20.01004.
- Functional Effects of Intervening Illnesses and Injuries After Critical Illness in Older Persons.Gill TM, Han L, Gahbauer EA, Leo-Summers L, Murphy TE, Ferrante LE. Functional Effects of Intervening Illnesses and Injuries After Critical Illness in Older Persons. Critical Care Medicine 2021, 49: 956-966. PMID: 33497167, PMCID: PMC8140984, DOI: 10.1097/ccm.0000000000004829.
- Pain, Complex Chronic Conditions and Potential Inappropriate Medication in People with Dementia. Lessons Learnt for Pain Treatment Plans Utilizing Data from the Veteran Health AdministrationHusebo BS, Kerns RD, Han L, Skanderson M, Gnjidic D, Allore HG. Pain, Complex Chronic Conditions and Potential Inappropriate Medication in People with Dementia. Lessons Learnt for Pain Treatment Plans Utilizing Data from the Veteran Health Administration Brain Sciences 2021, 11: 86. PMID: 33440668, PMCID: PMC7827274, DOI: 10.3390/brainsci11010086.
- Complementary and Integrative Health Approaches Are Underused Among Older Veterans With Musculoskeletal PainHan L, Kerns R, Skanderson M, Luther S, Fodeh S, Goulet J, Brandt C. Complementary and Integrative Health Approaches Are Underused Among Older Veterans With Musculoskeletal Pain Innovation In Aging 2020, 4: 203-203. PMCID: PMC7740151, DOI: 10.1093/geroni/igaa057.657.
- Cognitive frailty in relation to adverse health outcomes independent of multimorbidity in Chinese older adultsLiu Z, Chen C, Park J, Wu C, Xue Q, Agogo G, Han L, Wu Z. Cognitive frailty in relation to adverse health outcomes independent of multimorbidity in Chinese older adults Innovation In Aging 2020, 4: 908-909. PMCID: PMC7741254, DOI: 10.1093/geroni/igaa057.3342.
- Guardianship and End‐of‐Life Care for Veterans with Dementia in Nursing HomesCohen AB, Han L, OʼLeary JR, Fried TR. Guardianship and End‐of‐Life Care for Veterans with Dementia in Nursing Homes Journal Of The American Geriatrics Society 2020, 69: 342-348. PMID: 33170957, PMCID: PMC7902349, DOI: 10.1111/jgs.16900.
- Functional Effects of Intervening Illnesses and Injuries After Hospitalization for Major Surgery in Community-living Older PersonsGill TM, Han L, Gahbauer EA, Leo-Summers L, Murphy TE, Becher RD. Functional Effects of Intervening Illnesses and Injuries After Hospitalization for Major Surgery in Community-living Older Persons Annals Of Surgery 2020, 273: 834-841. PMID: 33074902, PMCID: PMC8370041, DOI: 10.1097/sla.0000000000004438.
- Risk Factors for Disability After Emergency Department Discharge in Older AdultsNagurney JM, Han L, Leo‐Summers L, Allore HG, Gill TM. Risk Factors for Disability After Emergency Department Discharge in Older Adults Academic Emergency Medicine 2020, 27: 1270-1278. PMID: 32673434, PMCID: PMC7749835, DOI: 10.1111/acem.14088.
- Risk Factors and Precipitants of Severe Disability Among Community-Living Older PersonsGill TM, Han L, Gahbauer EA, Leo-Summers L, Murphy TE. Risk Factors and Precipitants of Severe Disability Among Community-Living Older Persons JAMA Network Open 2020, 3: e206021. PMID: 32484551, PMCID: PMC7267844, DOI: 10.1001/jamanetworkopen.2020.6021.
- 0852 Geriatric Health Conditions And The Combined Outcome Of Poor Sleep Quality With Objective Short Sleep DurationMiner B, Vaz Fragoso C, Han L, Yaggi H, Redeker N, Stone K. 0852 Geriatric Health Conditions And The Combined Outcome Of Poor Sleep Quality With Objective Short Sleep Duration Sleep 2020, 43: a324-a325. DOI: 10.1093/sleep/zsaa056.848.
- 0855 Primary Sleep Disorders And The Combined Outcome Of Poor Sleep Quality With Objective Short Sleep Duration In Older PersonsMiner B, Vaz Fragoso C, Han L, Stone K, Redeker N, Yaggi H. 0855 Primary Sleep Disorders And The Combined Outcome Of Poor Sleep Quality With Objective Short Sleep Duration In Older Persons Sleep 2020, 43: a325-a326. DOI: 10.1093/sleep/zsaa056.851.
- Aggressive care at end-of-life in the Veteran’s Health Administration versus fee-for-service Medicare among patients with advanced lung cancer.Presley C, Kaur K, Han L, Soulos P, Zhu W, Corneau E, O'Leary J, Chao H, Shamas T, Rose M, Lorenz K, Levy C, Mor V, Gross C. Aggressive care at end-of-life in the Veteran’s Health Administration versus fee-for-service Medicare among patients with advanced lung cancer. Journal Of Clinical Oncology 2020, 38: 12025-12025. DOI: 10.1200/jco.2020.38.15_suppl.12025.
- Cohort Profile: The Precipitating Events Project (PEP Study)Gill T, Han L, Gahbauer EA, Leo-Summers L, Murphy TE. Cohort Profile: The Precipitating Events Project (PEP Study) The Journal Of Nutrition, Health & Aging 2020, 24: 438-444. PMID: 32242212, PMCID: PMC7322244, DOI: 10.1007/s12603-020-1341-4.
- USE OF EXPOSURE CROSSOVER DESIGN TO CONTROL FOR UNMEASURED BASELINE CONFOUNDING IN OBSERVATIONAL STUDIESHan L, Kerns R, Skanderson M, Goulet J, Luther S, Brandt C. USE OF EXPOSURE CROSSOVER DESIGN TO CONTROL FOR UNMEASURED BASELINE CONFOUNDING IN OBSERVATIONAL STUDIES Innovation In Aging 2019, 3: s479-s480. PMCID: PMC6840900, DOI: 10.1093/geroni/igz038.1785.
- BURDEN OF POTENTIALLY INAPPROPRIATE MEDICATIONS AMONG OLDER VETERANS WITH PAIN AND DEMENTIAAllore H, Gnjidic D, Han L. BURDEN OF POTENTIALLY INAPPROPRIATE MEDICATIONS AMONG OLDER VETERANS WITH PAIN AND DEMENTIA Innovation In Aging 2019, 3: s717-s718. PMCID: PMC6845988, DOI: 10.1093/geroni/igz038.2632.
- JOINT TRAJECTORIES OF COGNITION AND FRAILTY, AND ASSOCIATED BURDEN OF PATIENT-REPORTED OUTCOMESLiu Z, Han L, Gahbauer E, Allore H, Gill T. JOINT TRAJECTORIES OF COGNITION AND FRAILTY, AND ASSOCIATED BURDEN OF PATIENT-REPORTED OUTCOMES Innovation In Aging 2018, 2: 23-24. PMCID: PMC6226846, DOI: 10.1093/geroni/igy023.085.
- Diabetes, Heart Disease, and Dementia: National Estimates of Functional Disability TrajectoriesVroomen J, Han L, Monin JK, Lipska KJ, Allore HG. Diabetes, Heart Disease, and Dementia: National Estimates of Functional Disability Trajectories Journal Of The American Geriatrics Society 2018, 66: 766-772. PMID: 29521414, PMCID: PMC5906138, DOI: 10.1111/jgs.15284.
- Disability Prior to Death Among the Oldest-Old in ChinaLiu Z, Han L, Wang X, Feng Q, Gill TM. Disability Prior to Death Among the Oldest-Old in China The Journals Of Gerontology Series A 2018, 73: 1701-1707. PMID: 29408957, PMCID: PMC6230206, DOI: 10.1093/gerona/gly010.
- Joint Trajectories of Cognition and Frailty and Associated Burden of Patient-Reported OutcomesLiu Z, Han L, Gahbauer EA, Allore HG, Gill TM. Joint Trajectories of Cognition and Frailty and Associated Burden of Patient-Reported Outcomes Journal Of The American Medical Directors Association 2017, 19: 304-309.e2. PMID: 29146224, PMCID: PMC6054444, DOI: 10.1016/j.jamda.2017.10.010.
- Opioid dosing trends over eight years among US Veterans with musculoskeletal disorders after returning from service in support of recent conflictsHan L, Allore H, Goulet J, Bathulapali H, Skanderson M, Brandt C, Haskell S, Krebs E. Opioid dosing trends over eight years among US Veterans with musculoskeletal disorders after returning from service in support of recent conflicts Annals Of Epidemiology 2017, 27: 563-569.e3. PMID: 28890282, PMCID: PMC5647654, DOI: 10.1016/j.annepidem.2017.08.015.
- Concurrent Care and Aggressive End-of-Life Lung Cancer CarePresley C, Han L, O'leary J, Chao H, Shamas T, Kerin A, Rose M, Gross C. Concurrent Care and Aggressive End-of-Life Lung Cancer Care Journal Of Thoracic Oncology 2017, 12: s1545. DOI: 10.1016/j.jtho.2017.06.058.
- HEART DISEASE, DIABETES AND DEMENTIA’S ASSOCIATION WITH FUNCTIONAL TRAJECTORIES OVER 5 YEARSVroomen J, Han L, Monin J, Allore H. HEART DISEASE, DIABETES AND DEMENTIA’S ASSOCIATION WITH FUNCTIONAL TRAJECTORIES OVER 5 YEARS Innovation In Aging 2017, 1: 598-599. PMCID: PMC6246203, DOI: 10.1093/geroni/igx004.2096.
- ESTIMATING TREATMENT EFFECT OF HALOPERIDOL ON DELIRIUM SYMPTOMS USING OBSERVATIONAL DATAHan L, Pisani M, Araujo K, Allore H. ESTIMATING TREATMENT EFFECT OF HALOPERIDOL ON DELIRIUM SYMPTOMS USING OBSERVATIONAL DATA Innovation In Aging 2017, 1: 965-965. PMCID: PMC6185498, DOI: 10.1093/geroni/igx004.3482.
- Functional trajectories before and after a new cancer diagnosis among community-living older adults.Presley C, Hurria A, Han L, Leo-Summers L, Gross C, Allore H, Davidoff A, Gill T. Functional trajectories before and after a new cancer diagnosis among community-living older adults. Journal Of Clinical Oncology 2017, 35: e21547-e21547. DOI: 10.1200/jco.2017.35.15_suppl.e21547.
- 0755 LONGITUDINAL ASSOCIATIONS OF RISK FACTORS WITH INSOMNIA SEVERITY IN OLDER PERSONSMiner B, Redeker N, Yaggi H, Van Ness P, Han L, Gill T, Fragoso C. 0755 LONGITUDINAL ASSOCIATIONS OF RISK FACTORS WITH INSOMNIA SEVERITY IN OLDER PERSONS Sleep 2017, 40: a280-a280. DOI: 10.1093/sleepj/zsx050.754.
- (346) Use of propensity score to facilitate causal inference when evaluating complementary health therapies among US veterans with chronic musculoskeletal painHan L, Goulet J, Skanderson M, Bathulpali H, Luther S, Kerns R, Brandt C. (346) Use of propensity score to facilitate causal inference when evaluating complementary health therapies among US veterans with chronic musculoskeletal pain Journal Of Pain 2017, 18: s61. DOI: 10.1016/j.jpain.2017.02.239.
- Effect of Aging and HIV Infection on the Function of Mincle, an Innate Immune Receptor for Cord Factor from M. tuberculosisZapata H, Siconolfi B, Mohanty S, Wilson J, Van Ness P, Han L, Barakat L, Shaw A. Effect of Aging and HIV Infection on the Function of Mincle, an Innate Immune Receptor for Cord Factor from M. tuberculosis Open Forum Infectious Diseases 2016, 3: 2192. DOI: 10.1093/ofid/ofw172.1740.
- P2‐413: Anticholinergic Drug Burden Predicts Delirium Severity Among Older Medical Patients Under Intensive CareHan L, Allore H, Araujo K, Pisani M. P2‐413: Anticholinergic Drug Burden Predicts Delirium Severity Among Older Medical Patients Under Intensive Care Alzheimer's & Dementia 2016, 12: p803-p803. DOI: 10.1016/j.jalz.2016.06.1625.
- Use of Self-Matching to Control for Stable Patient Characteristics While Addressing Time-Varying Confounding on Treatment Effect: A Case Study of Older Intensive Care PatientsHan L, Pisani MA, Araujo KL, Allore HG. Use of Self-Matching to Control for Stable Patient Characteristics While Addressing Time-Varying Confounding on Treatment Effect: A Case Study of Older Intensive Care Patients International Journal Of Statistics In Medical Research 2016, 5: 8-16. PMID: 27123153, PMCID: PMC4844076, DOI: 10.6000/1929-6029.2016.05.01.2.
- Trajectories of Disability Among Older Persons Before and After a Hospitalization Leading to a Skilled Nursing Facility AdmissionBuurman BM, Han L, Murphy TE, Gahbauer EA, Leo-Summers L, Allore HG, Gill TM. Trajectories of Disability Among Older Persons Before and After a Hospitalization Leading to a Skilled Nursing Facility Admission Journal Of The American Medical Directors Association 2015, 17: 225-231. PMID: 26620073, PMCID: PMC4769913, DOI: 10.1016/j.jamda.2015.10.010.
- Cognitive Aging Trajectories and Burdens of Disability, Hospitalization and Nursing Home Admission Among Community-living Older PersonsHan L, Gill TM, Jones BL, Allore HG. Cognitive Aging Trajectories and Burdens of Disability, Hospitalization and Nursing Home Admission Among Community-living Older Persons The Journals Of Gerontology Series A 2015, 71: 766-771. PMID: 26511011, PMCID: PMC4888384, DOI: 10.1093/gerona/glv159.
- The role of intervening hospital admissions on trajectories of disability in the last year of life: prospective cohort study of older peopleGill TM, Gahbauer EA, Han L, Allore HG. The role of intervening hospital admissions on trajectories of disability in the last year of life: prospective cohort study of older people The BMJ 2015, 350: h2361. PMID: 25995357, PMCID: PMC4443433, DOI: 10.1136/bmj.h2361.
- A Longitudinal, Observational Study with Many Repeated Measures Demonstrated Improved Precision of Individual Survival Curves Using Bayesian Joint Modeling of Disability and SurvivalMurphy TE, G. Allore HG, Han L, Peduzzi PN, Gill TM, Xu X, Lin HQ. A Longitudinal, Observational Study with Many Repeated Measures Demonstrated Improved Precision of Individual Survival Curves Using Bayesian Joint Modeling of Disability and Survival, Experimental Aging Research, 2015;41:3, 221-239, DOI: 10.1080/0361073X.2015.1021640
- Establishing a Hierarchy for the Two Components of Restricted ActivityGill TM, Allore HG, Gahbauer EA, Han L. Establishing a Hierarchy for the Two Components of Restricted Activity The Journals Of Gerontology Series A 2014, 70: 892-898. PMID: 25391532, PMCID: PMC4481688, DOI: 10.1093/gerona/glu203.
- Antihypertensive Medications and Serious Fall Injuries in a Nationally Representative Sample of Older AdultsTinetti ME, Han L, Lee DS, McAvay GJ, Peduzzi P, Gross CP, Zhou B, Lin H. Antihypertensive Medications and Serious Fall Injuries in a Nationally Representative Sample of Older Adults JAMA Internal Medicine 2014, 174: 588-595. PMID: 24567036, PMCID: PMC4136657, DOI: 10.1001/jamainternmed.2013.14764.
- Anti-Hypertensive Medications and Cardiovascular Events in Older Adults with Multiple Chronic ConditionsTinetti ME, Han L, McAvay GJ, Lee DS, Peduzzi P, Dodson JA, Gross CP, Zhou B, Lin H. Anti-Hypertensive Medications and Cardiovascular Events in Older Adults with Multiple Chronic Conditions PLOS ONE 2014, 9: e90733. PMID: 24614535, PMCID: PMC3948696, DOI: 10.1371/journal.pone.0090733.
- A dynamic trajectory class model for intensive longitudinal categorical outcomeLin H, Han L, Peduzzi PN, Murphy TE, Gill TM, Allore HG. A dynamic trajectory class model for intensive longitudinal categorical outcome Statistics In Medicine 2014, 33: 2645-2664. PMID: 24519416, PMCID: PMC4145078, DOI: 10.1002/sim.6109.
- Epidemiology of Restricting Fatigue in Older Adults: The Precipitating Events ProjectRekeneire N, Leo‐Summers L, Han L, Gill TM. Epidemiology of Restricting Fatigue in Older Adults: The Precipitating Events Project Journal Of The American Geriatrics Society 2014, 62: 476-481. PMID: 24512073, PMCID: PMC4103720, DOI: 10.1111/jgs.12685.
- Risk Factors for Restricting Back Pain in Older PersonsMakris UE, Fraenkel L, Han L, Leo-Summers L, Gill TM. Risk Factors for Restricting Back Pain in Older Persons Journal Of The American Medical Directors Association 2013, 15: 62-67. PMID: 24239445, PMCID: PMC3872215, DOI: 10.1016/j.jamda.2013.09.013.
- The impact of medication use on symptom burden in older patients with multiple medical morbiditiesHan M, Tinetti M, Agostini J, Han L, Lee H, Walke L. The impact of medication use on symptom burden in older patients with multiple medical morbidities Journal Of Clinical Gerontology And Geriatrics 2013, 4: 84-88. DOI: 10.1016/j.jcgg.2013.03.002.
- Dynamics of functional aging based on latent-class trajectories of activities of daily livingHan L, Allore H, Murphy T, Gill T, Peduzzi P, Lin H. Dynamics of functional aging based on latent-class trajectories of activities of daily living Annals Of Epidemiology 2013, 23: 87-92. PMID: 23305692, PMCID: PMC3558979, DOI: 10.1016/j.annepidem.2012.11.010.
- Comparisons Between Older Men and Women in the Trajectory and Burden of Disability Over the Course of Nearly 14 YearsGill TM, Gahbauer EA, Lin H, Han L, Allore HG. Comparisons Between Older Men and Women in the Trajectory and Burden of Disability Over the Course of Nearly 14 Years Journal Of The American Medical Directors Association 2013, 14: 280-286. PMID: 23294968, PMCID: PMC3615123, DOI: 10.1016/j.jamda.2012.11.011.
- Risk factors and precipitants of long-term disability in community mobility: a cohort study of older persons.Gill TM, Gahbauer EA, Murphy TE, Han L, Allore HG. Risk factors and precipitants of long-term disability in community mobility: a cohort study of older persons. Annals Of Internal Medicine 2012, 156: 131-40. PMID: 22250144, PMCID: PMC3278794, DOI: 10.7326/0003-4819-156-2-201201170-00009.
- Antidepressant Use and Cognitive Deficits in Older Men: Addressing Confounding by Indications with Different MethodsHan L, Kim N, Brandt C, Allore HG. Antidepressant Use and Cognitive Deficits in Older Men: Addressing Confounding by Indications with Different Methods Annals Of Epidemiology 2011, 22: 9-16. PMID: 22037381, PMCID: PMC4054866, DOI: 10.1016/j.annepidem.2011.10.004.
- The Relationship Between Intervening Hospitalizations and Transitions Between Frailty StatesGill TM, Gahbauer EA, Han L, Allore HG. The Relationship Between Intervening Hospitalizations and Transitions Between Frailty States The Journals Of Gerontology Series A 2011, 66A: 1238-1243. PMID: 21852286, PMCID: PMC3193526, DOI: 10.1093/gerona/glr142.
- Antidepressant Use and Cognitive Functioning in Older Medical Patients With Major or Minor DepressionHan L, McCusker J, Cole M, apek R, Abrahamowicz M. Antidepressant Use and Cognitive Functioning in Older Medical Patients With Major or Minor Depression Journal Of Clinical Psychopharmacology 2011, 31: 429-435. PMID: 21694621, PMCID: PMC3558972, DOI: 10.1097/jcp.0b013e318221b2f8.
- Gerontologic research algorithms and statistical programs (GRASP): A web-based biostatistical repository for gerontological researchersHan L, Allore H, Group O. Gerontologic research algorithms and statistical programs (GRASP): A web-based biostatistical repository for gerontological researchers Alzheimer's & Dementia 2010, 6: s318-s319. DOI: 10.1016/j.jalz.2010.05.1040.
- P3‐066: Antidepressant use and cognitive function in older primary care patients with major or minor depression: A prospective cohort study with database linkageHan L, McCusker J, Cole M, Capek R, Abrahamowicz M. P3‐066: Antidepressant use and cognitive function in older primary care patients with major or minor depression: A prospective cohort study with database linkage Alzheimer's & Dementia 2010, 6: s468-s468. DOI: 10.1016/j.jalz.2010.05.1560.
- Trajectories of Disability in the Last Year of LifeGill TM, Gahbauer EA, Han L, Allore HG. Trajectories of Disability in the Last Year of Life New England Journal Of Medicine 2010, 362: 1173-1180. PMID: 20357280, PMCID: PMC2877372, DOI: 10.1056/nejmoa0909087.
- Top cited papers in International Psychogeriatrics: 6c. Tracking cognitive decline in Alzheimer's disease using the Mini-mental State Examination: a meta-analysis ("mini" is not necessarily trivial!).Han L. Top cited papers in International Psychogeriatrics: 6c. Tracking cognitive decline in Alzheimer's disease using the Mini-mental State Examination: a meta-analysis ("mini" is not necessarily trivial!). International Psychogeriatrics / IPA 2009, 21: 1037-40. PMID: 19747422, DOI: 10.1017/S1041610209990883.
- Factors Associated With Recovery of Prehospital Function Among Older Persons Admitted to a Nursing Home With Disability After an Acute HospitalizationGill TM, Gahbauer EA, Han L, Allore HG. Factors Associated With Recovery of Prehospital Function Among Older Persons Admitted to a Nursing Home With Disability After an Acute Hospitalization The Journals Of Gerontology Series A 2009, 64A: 1296-1303. PMID: 19661289, PMCID: PMC2773809, DOI: 10.1093/gerona/glp115.
- Cumulative Anticholinergic Exposure Is Associated with Poor Memory and Executive Function in Older MenHan L, Agostini JV, Allore HG. Cumulative Anticholinergic Exposure Is Associated with Poor Memory and Executive Function in Older Men Journal Of The American Geriatrics Society 2008, 56: 2203-2210. PMID: 19093918, PMCID: PMC3952110, DOI: 10.1111/j.1532-5415.2008.02009.x.
- The Temporal Relationship Between Depression Symptoms and Cognitive Functioning in Older Medical Patients—Prospective or Concurrent?Han L, McCusker J, Abrahamowicz M, Cole M, Capek R. The Temporal Relationship Between Depression Symptoms and Cognitive Functioning in Older Medical Patients—Prospective or Concurrent? The Journals Of Gerontology Series A 2006, 61: 1319-1323. PMID: 17234828, DOI: 10.1093/gerona/61.12.1319.
- Short- and Long-term Functional Outcome of Hospitalized Older Adults With Community-acquired PneumoniaSharma G, Han L, Quagliarello V. Short- and Long-term Functional Outcome of Hospitalized Older Adults With Community-acquired Pneumonia Infectious Diseases In Clinical Practice 2006, 14: 365-368. DOI: 10.1097/01.idc.0000227715.26754.e7.
- The Temporal Relationship between Depression Symptoms and Cognitive Functioning in Older Medical Patients — Prospective or Concurrent?Han L, McCusker J, Abrahamowicz M, Cole M, Capek R. The Temporal Relationship between Depression Symptoms and Cognitive Functioning in Older Medical Patients — Prospective or Concurrent? American Journal Of Epidemiology 2006, 163: s175-s175. DOI: 10.1093/aje/163.suppl_11.s175-c.
- Transitions Between Frailty States Among Community-Living Older PersonsGill TM, Gahbauer EA, Allore HG, Han L. Transitions Between Frailty States Among Community-Living Older Persons JAMA Internal Medicine 2006, 166: 418-423. PMID: 16505261, DOI: 10.1001/archinte.166.4.418.
- 189-S: The Temporal Relationship Between Depression and Cognitive Functioning in Older Medical Patients — Prospective or Cross-Sectional?Han L, McCusker J, Abrahamowicz M, Cole M, Capek R. 189-S: The Temporal Relationship Between Depression and Cognitive Functioning in Older Medical Patients — Prospective or Cross-Sectional? American Journal Of Epidemiology 2005, 161: s48-s48. DOI: 10.1093/aje/161.supplement_1.s48.
- The Course of Delirium in Older Medical InpatientsMcCusker J, Cole M, Dendukuri N, Han L, Belzile É. The Course of Delirium in Older Medical Inpatients Journal Of General Internal Medicine 2003, 18: 696-704. PMID: 12950477, PMCID: PMC1494920, DOI: 10.1046/j.1525-1497.2003.20602.x.
- An Empirical Study of Different Diagnostic Criteria for Delirium Among Elderly Medical InpatientsCole MG, Dendukuri N, McCusker J, Han L. An Empirical Study of Different Diagnostic Criteria for Delirium Among Elderly Medical Inpatients Journal Of Neuropsychiatry 2003, 15: 200-207. PMID: 12724462, DOI: 10.1176/jnp.15.2.200.
- Symptoms of Delirium Among Elderly Medical Inpatients With or Without DementiaCole MG, McCusker J, Dendukuri N, Han L. Symptoms of Delirium Among Elderly Medical Inpatients With or Without Dementia Journal Of Neuropsychiatry 2002, 14: 167-175. PMID: 11983791, DOI: 10.1176/jnp.14.2.167.
- Environmental Risk Factors for Delirium in Hospitalized Older PeopleMcCusker J, Cole M, Abrahamowicz M, Han L, Podoba J, Ramman‐Haddad L. Environmental Risk Factors for Delirium in Hospitalized Older People Journal Of The American Geriatrics Society 2001, 49: 1327-1334. PMID: 11890491, DOI: 10.1046/j.1532-5415.2001.49260.x.
- Use of Medications With Anticholinergic Effect Predicts Clinical Severity of Delirium Symptoms in Older Medical InpatientsHan L, McCusker J, Cole M, Abrahamowicz M, Primeau F, Elie M. Use of Medications With Anticholinergic Effect Predicts Clinical Severity of Delirium Symptoms in Older Medical Inpatients JAMA Internal Medicine 2001, 161: 1099-1105. PMID: 11322844, DOI: 10.1001/archinte.161.8.1099.
- Ultradian oscillations in cranial thermoregulation and electroencephalographic slow-wave activity during sleep are abnormal in humans with annual winter depression.Schwartz PJ, Rosenthal NE, Kajimura N, Han L, Turner EH, Bender C, Wehr TA. Ultradian oscillations in cranial thermoregulation and electroencephalographic slow-wave activity during sleep are abnormal in humans with annual winter depression. Brain Research 2000, 866: 152-67. PMID: 10825491, DOI: 10.1016/s0006-8993(00)02271-x.
- Tracking Cognitive Decline in Alzheimer's Disease Using the Mini-Mental State Examination: A Meta-AnalysisHan L, Cole M, Bellavance F, McCusker J, Primeau F. Tracking Cognitive Decline in Alzheimer's Disease Using the Mini-Mental State Examination: A Meta-Analysis International Psychogeriatrics 2000, 12: 231-247. PMID: 10937543, DOI: 10.1017/s1041610200006359.
- Seasonal variations in mood and behavior among Chinese medical students.Han L, Wang K, Du Z, Cheng Y, Simons JS, Rosenthal NE. Seasonal variations in mood and behavior among Chinese medical students. The American Journal Of Psychiatry 2000, 157: 133-5. PMID: 10618029, DOI: 10.1176/ajp.157.1.133.
- Summer and winter patterns of seasonality in Chinese college students: a replication.Han L, Wang K, Cheng Y, Du Z, Rosenthal NE, Primeau F. Summer and winter patterns of seasonality in Chinese college students: a replication. Comprehensive Psychiatry 2000, 41: 57-62. PMID: 10646620, DOI: 10.1016/s0010-440x(00)90132-9.
- Monorhinal odor identification and depression scores in patients with seasonal affective disorder.Postolache TT, Doty RL, Wehr TA, Jimma LA, Han L, Turner EH, Matthews JR, Neumeister A, No C, Kroger H, Bruder GE, Rosenthal NE. Monorhinal odor identification and depression scores in patients with seasonal affective disorder. Journal Of Affective Disorders 1999, 56: 27-35. PMID: 10626777, DOI: 10.1016/s0165-0327(99)00027-0.
- No coding variant of the tryptophan hydroxylase gene detected in seasonal affective disorder, obsessive-compulsive disorder, anorexia nervosa, and alcoholism.Han L, Nielsen DA, Rosenthal NE, Jefferson K, Kaye W, Murphy D, Altemus M, Humphries J, Cassano G, Rotondo A, Virkkunen M, Linnoila M, Goldman D. No coding variant of the tryptophan hydroxylase gene detected in seasonal affective disorder, obsessive-compulsive disorder, anorexia nervosa, and alcoholism. Biological Psychiatry 1999, 45: 615-9. PMID: 10088048, DOI: 10.1016/s0006-3223(98)00122-x.
- Descriptive validity and stability of diagnostic criteria for dysthymic disorder.Han L, Schmaling KB, Dunner DL. Descriptive validity and stability of diagnostic criteria for dysthymic disorder. Comprehensive Psychiatry 1995, 36: 338-43. PMID: 7497707, DOI: 10.1016/s0010-440x(95)90114-0.