Charles Matouk, MD
Research & Publications
Biography
News
Research Summary
My translational research interests can be divided along two thematic lines: (1) clinical trials implementation and design in neurological disease, and (2) advanced imaging in cerebrovascular disease.
Specialized Terms: Translational application of advanced imaging protocols in neurovascular disease; clinical trials
Extensive Research Description
1. CLINICAL TRIALS
I am currently involved in the following national and international, multi-center clinical trials that are enrolling (or about to enroll) at Yale-New Haven Hospital.
Brain Aneurysms / Subarachnoid Hemorrhage
ASTROH Trial. A multi-center, phase II randomized clinical trial of continuous low-dose IV heparin therapy in coiled low-grade aneurysmal SAH patients with significant hemorrhage burden. [My role: site-PI.]
NEWTON Trial. A multi-center, phase 3 randomized, double-blinded, placebo-controlled efficacy and safety study comparing EG-1962 to standard of care oral nimodipine in adults with aneurysmal subarachnoid hemorrhage. [My role: site-PI.]
Carotid Revascularization
CONFIDENCE Trial. A prospective, multi-center, single-arm, open-label clinical study to evaluate the safety and efficacy of Roadsaver carotid stent device used in conjunction with the Nanoparasol embolic protection system for the treatment of carotid artery stenosis in patients with elevated risk for adverse events following carotid endarterectomy. [My role: site-PI.]
CREST-2. Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in patients with asymptomatic high-grade carotid stenosis. [My role: sub-investigator, interventionist.]
Intracranial Hemorrhage
MISTIE-III. The purpose of this trial is to determine the safety of using a combination of minimally invasive surgery and clot lysis with rt-PA to remove intracerebral hemorrhage (ICH). [My role: site-co-PI, lead surgeon.]
2. ADVANCED IMAGING RESEARCH
My translational research is focused on advanced imaging of the critically ill neurovascular patient. Our overall aim is to improve the safety and quality of care rendered to patient's with cerebrovascular disease.
Coauthors
Research Interests
Cerebrovascular Disorders; Diagnostic Techniques, Neurological; Endothelium, Vascular; Neurosurgery; Radiology; Clinical Trial
Selected Publications
- Automated detection of early signs of irreversible ischemic change on CTA source images in patients with large vessel occlusionMak A, Matouk C, Avery E, Behland J, Haider S, Frey D, Madai V, Vajkoczy P, Griessenauer C, Zand R, Hendrix P, Abedi V, Sanelli P, Falcone G, Petersen N, Sansing L, Sheth K, Payabvash S, Malhotra A. Automated detection of early signs of irreversible ischemic change on CTA source images in patients with large vessel occlusion. PLOS ONE 2024, 19: e0304962. PMID: 38870240, PMCID: PMC11175522, DOI: 10.1371/journal.pone.0304962.
- Outcomes and differences by occluded vessel after endovascular thrombectomy for isolated medium vessel occlusionsMatsukawa H, Uchida K, Cunningham C, Sowlat M, Elawady S, Maier I, Jabbour P, Kim J, Wolfe S, Rai A, Starke R, Psychogios M, Shaban A, Arthur A, Cuellar H, Howard B, Alawieh A, Romano D, Tanweer O, Mascitelli J, Fragata I, Polifka A, Osbun J, Crosa R, Matouk C, Park M, Brinjikji W, Moss M, Williamson R, Navia P, Kan P, De Leacy R, Chowdhry S, Ezzeldin M, Spiotta A, Levitt M, Yoshimura S, Collaborators F. Outcomes and differences by occluded vessel after endovascular thrombectomy for isolated medium vessel occlusions. Journal Of The Neurological Sciences 2024, 462: 123054. PMID: 38889600, DOI: 10.1016/j.jns.2024.123054.
- Use of a dedicated open transcarotid access system for neurovascular diseaseSujijantarat N, Renedo D, Antonios J, Koo A, Amllay A, Nowicki K, Cord B, Hebert R, de Havenon A, Sheth K, Petersen N, Matouk C. Use of a dedicated open transcarotid access system for neurovascular disease. Journal Of NeuroInterventional Surgery 2024, jnis-2024-021599. PMID: 38719442, DOI: 10.1136/jnis-2024-021599.
- Angiographic evidence of an inadvertent cannulation of the marginal sinus following central line migration: illustrative caseAmllay A, Owolo E, Nowicki K, Sujijantarat N, Koo A, Antonios J, Renedo D, Matouk C, Hebert R. Angiographic evidence of an inadvertent cannulation of the marginal sinus following central line migration: illustrative case. Journal Of Neurosurgery Case Lessons 2024, 7: case23607. PMID: 38684119, PMCID: PMC11058405, DOI: 10.3171/case23607.
- The Impact of Preprocedural Platelet Function Testing on Periprocedural Complication Rates Associated With Pipeline Flow Diversion: An International Multicenter StudyVranic J, Dmytriw A, Berglar I, Alotaibi N, Cancelliere N, Stapleton C, Rabinov J, Harker P, Gupta R, Bernstock J, Koch M, Raymond S, Mascitelli J, Patterson T, Seinfeld J, White A, Case D, Roark C, Gandhi C, Al-Mufti F, Cooper J, Matouk C, Sujijantarat N, Devia D, Ocampo-Navia M, Villamizar-Torres D, Puentes J, Salem M, Baig A, Namaani K, Kühn A, Pukenas B, Jankowitz B, Burkhardt J, Siddiqui A, Jabbour P, Singh J, Puri A, Regenhardt R, Pereira V, Patel A. The Impact of Preprocedural Platelet Function Testing on Periprocedural Complication Rates Associated With Pipeline Flow Diversion: An International Multicenter Study. Neurosurgery 2024, 95: 179-185. PMID: 38634693, DOI: 10.1227/neu.0000000000002956.
- The eShunt® System: A Novel Minimally Invasive CSF Shunting System for the Treatment of Idiopathic Normal Pressure Hydrocephalus (P10-4.014)Lylyk P, Matouk C, Siddiqui A, Riina H, Lylyk I, Bleise C, Scrivano E, Lylyk P, Antonios J, Beneduce B, Levy E, Heilman C, Malek A. The eShunt® System: A Novel Minimally Invasive CSF Shunting System for the Treatment of Idiopathic Normal Pressure Hydrocephalus (P10-4.014). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206181.
- Assessing Effects of Intrathecal Nicardipine on Cerebral Autoregulation and Cortical Activity in Aneurysmal Subarachnoid Hemorrhage (P10-5.019)Jayasundara S, Kim J, Choi R, Rapuano A, Barnes E, Parasram M, Moura M, Uppal P, Chen Y, Top I, Olexa M, Maarek R, Yan J, Beekman R, Magid-Bernstein J, Hebert R, Bahrassa F, Matouk C, Sheth K, Gilmore E, Petersen N. Assessing Effects of Intrathecal Nicardipine on Cerebral Autoregulation and Cortical Activity in Aneurysmal Subarachnoid Hemorrhage (P10-5.019). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206285.
- Different Response to Blood Pressure Reduction in Lobar and Deep Intracerebral Hemorrhage (P10-2.004)Hawkes M, Clocchiatti-Tuozzo S, Rivier C, Qureshi A, Matouk C, Petersen N, De Havenon A, Sheth K, Falcone G. Different Response to Blood Pressure Reduction in Lobar and Deep Intracerebral Hemorrhage (P10-2.004). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206366.
- Exploring the Relationship Between Cerebrospinal Fluid Interleukin-6 and Cerebral Autoregulation After Subarachnoid Hemorrhage (S23.004)Olexa M, Begunova Y, Gilmore E, Kim J, Herman A, Beekman R, Magid-Bernstein J, Matouk C, Sheth K, Miller E, Gutierrez S, De Havenon A, Sansing L, Petersen N. Exploring the Relationship Between Cerebrospinal Fluid Interleukin-6 and Cerebral Autoregulation After Subarachnoid Hemorrhage (S23.004). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205692.
- Quantitative Assessment of Reperfusion Impact on Cerebral Edema and Functional Outcomes in Large-vessel Occlusion Stroke Patients (S23.003)Olexa M, Begunova Y, Dhar R, Matouk C, Sheth K, Gutierrez S, De Havenon A, Petersen N. Quantitative Assessment of Reperfusion Impact on Cerebral Edema and Functional Outcomes in Large-vessel Occlusion Stroke Patients (S23.003). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205719.
- 157 Minimally Invasive Treatment of Idiopathic Normal Pressure Hydrocephalus Using the Endovascular eShunt ImplantLylyk P, Matouk C, Siddiqui A, Lylyk I, Bleise C, Scrivano E, Lylyk N, Antonios J, Beneduce B, Levy E, Heilman C, Malek A. 157 Minimally Invasive Treatment of Idiopathic Normal Pressure Hydrocephalus Using the Endovascular eShunt Implant. Neurosurgery 2024, 70: 36-37. DOI: 10.1227/neu.0000000000002809_157.
- 308 Improvement in Cranial Nerve Neuropathies Following Treatment of Intracranial Aneurysms With Flow Diverters: Institutional Outcomes and Meta-analysis of LiteratureSujijantarat N, Antonios J, Koo A, Haynes J, Renedo D, Hebert R, Sheth K, King J, Matouk C. 308 Improvement in Cranial Nerve Neuropathies Following Treatment of Intracranial Aneurysms With Flow Diverters: Institutional Outcomes and Meta-analysis of Literature. Neurosurgery 2024, 70: 89-89. DOI: 10.1227/neu.0000000000002809_308.
- 306 Endothelial Infiltrating Regulatory B Cells and NK T Cells Precipitate Inflammatory Cascade That Leads to Aneurysmal RuptureAntonios J, Barak T, Gultekin B, Yalcin K, Adenu-Mensah N, Sujijantarat N, Koo A, Haynes J, Hebert R, Matouk C, Gunel M. 306 Endothelial Infiltrating Regulatory B Cells and NK T Cells Precipitate Inflammatory Cascade That Leads to Aneurysmal Rupture. Neurosurgery 2024, 70: 88-89. DOI: 10.1227/neu.0000000000002809_306.
- Impact of Procedure Time on First Pass Effect in Mechanical Thrombectomy for Anterior Circulation Acute Ischemic StrokeKoo A, Reeves B, Renedo D, Maier I, Al Kasab S, Jabbour P, Kim J, Wolfe S, Rai A, Starke R, Psychogios M, Shaban A, Arthur A, Yoshimura S, Cuellar H, Grossberg J, Alawieh A, Romano D, Tanweer O, Mascitelli J, Fragata I, Polifka A, Osbun J, Crosa R, Park M, Levitt M, Brinjikji W, Moss M, Dumont T, Williamson R, Navia P, Kan P, Spiotta A, Sheth K, de Havenon A, Matouk C. Impact of Procedure Time on First Pass Effect in Mechanical Thrombectomy for Anterior Circulation Acute Ischemic Stroke. Neurosurgery 2024, 95: 128-136. PMID: 38483158, DOI: 10.1227/neu.0000000000002900.
- Endovascular Treatment of Acute Ischemic Stroke After Cardiac Interventions in the United Statesde Havenon A, Zhou L, Koo A, Matouk C, Falcone G, Sharma R, Ney J, Shu L, Yaghi S, Kamel H, Sheth K. Endovascular Treatment of Acute Ischemic Stroke After Cardiac Interventions in the United States. JAMA Neurology 2024, 81: 264-272. PMID: 38285452, PMCID: PMC10825786, DOI: 10.1001/jamaneurol.2023.5416.
- Radiomics-Based Prediction of Collateral Status from CT Angiography of Patients Following a Large Vessel Occlusion StrokeAvery E, Abou-Karam A, Abi-Fadel S, Behland J, Mak A, Haider S, Zeevi T, Sanelli P, Filippi C, Malhotra A, Matouk C, Falcone G, Petersen N, Sansing L, Sheth K, Payabvash S. Radiomics-Based Prediction of Collateral Status from CT Angiography of Patients Following a Large Vessel Occlusion Stroke. Diagnostics 2024, 14: 485. PMID: 38472957, PMCID: PMC10930945, DOI: 10.3390/diagnostics14050485.
- Diagnostic accuracy of intraoperative neuromonitoring in transcarotid artery revascularizationDiogo C, Na D, Sujijantarat N, Matouk C, Callahan B. Diagnostic accuracy of intraoperative neuromonitoring in transcarotid artery revascularization. Journal Of NeuroInterventional Surgery 2024, jnis-2023-021282. PMID: 38378240, DOI: 10.1136/jnis-2023-021282.
- APOE ε4 and Intracerebral Hemorrhage in Patients With Brain Arteriovenous MalformationRenedo D, Rivier C, Koo A, Sujijantarat N, Clocchiatti-Tuozzo S, Wu K, Torres-Lopez V, Huo S, Gunel M, de Havenon A, Sheth K, Matouk C, Falcone G. APOE ε4 and Intracerebral Hemorrhage in Patients With Brain Arteriovenous Malformation. JAMA Network Open 2024, 7: e2355368. PMID: 38363572, PMCID: PMC10873768, DOI: 10.1001/jamanetworkopen.2023.55368.
- Abstract 89: Portable, Low-Field Magnetic Resonance Imaging: Determining Mismatch Following Acute Ischemic StrokeSorby-Adams A, Guo J, Schleicher R, Mazurek M, Baldassano S, Payavbash S, Sze G, Schindler J, de Havenon A, Goldstein J, Schaefer P, Zabinska J, Lalwani D, Wira C, Matouk C, Lee V, Muir K, Nimjee S, Pinter N, Siddiqui A, Kirsch J, Iglesias J, Rosen M, Sheth K, Kimberly W. Abstract 89: Portable, Low-Field Magnetic Resonance Imaging: Determining Mismatch Following Acute Ischemic Stroke. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.89.
- Abstract 54: Investigating the Relationship Between Reperfusion and Cerebral Edema Using Novel Cerebrospinal Fluid and Net Water Uptake BiomarkersOlexa M, Begunova Y, Dhar R, Matouk C, Sheth K, Ortega-Gutierrez S, de Havenon A, Petersen N. Abstract 54: Investigating the Relationship Between Reperfusion and Cerebral Edema Using Novel Cerebrospinal Fluid and Net Water Uptake Biomarkers. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.54.
- Abstract WP152: Association Between Cerebrospinal Fluid Interleukin-6 Levels and Cerebral Autoregulation After Aneurysmal Subarachnoid HemorrhageOlexa M, Begunova Y, Yan J, Herman A, Gilmore E, Kim J, Beekman R, Magid-Bernstein J, Matouk C, Sheth K, Miller E, Ortega-Gutierrez S, de Havenon A, Sansing L, Petersen N. Abstract WP152: Association Between Cerebrospinal Fluid Interleukin-6 Levels and Cerebral Autoregulation After Aneurysmal Subarachnoid Hemorrhage. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.wp152.
- Abstract WP159: Chronic Kidney Disease and Risk of Intracerebral Hemorrhage: The Role of Hypertension as a MediatorVanent K, Rivier C, Matouk C, Levitt M, Leslie-Mazwi T, Gill T, Sheth K, Falcone G. Abstract WP159: Chronic Kidney Disease and Risk of Intracerebral Hemorrhage: The Role of Hypertension as a Mediator. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.wp159.
- Abstract HUP7: Impact of Social Determinants of Health and Academic Hospital Care on Outcomes After Non-Traumatic Subarachnoid HemorrhageRenedo D, Rivier C, Clocchiatti-Tuozzo S, Huo S, Hebert R, Gunel M, Matouk C, Falcone G, Sheth K. Abstract HUP7: Impact of Social Determinants of Health and Academic Hospital Care on Outcomes After Non-Traumatic Subarachnoid Hemorrhage. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.hup7.
- Abstract 51: Impact of Cerebral Autoregulation on the Relationship Between Blood Pressure Variability and Functional Outcome Following Endovascular ThrombectomyPetersen N, Olexa M, Jayasundara S, Falcone G, Gilmore E, Kim J, Matouk C, Alian A, Sheth K, Miller E, Ortega-Gutierrez S, de Havenon A. Abstract 51: Impact of Cerebral Autoregulation on the Relationship Between Blood Pressure Variability and Functional Outcome Following Endovascular Thrombectomy. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.51.
- Abstract 149: Different Response to Blood Pressure Reduction in Lobar and Deep Intracerebral HemorrhageHawkes M, Clocchiatti-Tuozzo S, Rivier C, Qureshi A, Matouk C, Petersen N, de Havenon A, Sheth K, Falcone G. Abstract 149: Different Response to Blood Pressure Reduction in Lobar and Deep Intracerebral Hemorrhage. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.149.
- Transcarotid Arterial Revascularization of Symptomatic Internal Carotid Artery Disease: A Systematic Review and Study-Level Meta-AnalysisGhannam M, AlMajali M, Khasiyev F, Dibas M, Al Qudah A, AlMajali F, Ghazaleh D, Shah A, Fayad F, Joudi K, Zaidat B, Childs C, Levy B, Abouainain Y, Brunschot D, Shu L, Goldstein E, Baig A, Roeder H, Henninger N, de Havenon A, Levy E, Matouk C, Derdeyn C, Leira E, Chaturvedi S, Yaghi S. Transcarotid Arterial Revascularization of Symptomatic Internal Carotid Artery Disease: A Systematic Review and Study-Level Meta-Analysis. Stroke 2024, 55: 921-930. PMID: 38299350, DOI: 10.1161/strokeaha.123.044246.
- COVID‐19 Infection Is Associated With Poor Outcomes in Patients With Intracerebral HemorrhageRenedo D, Leasure A, Young R, Rivier C, Alhanti B, Mac Grory B, Messe S, Reeves M, Hassan A, Schwamm L, de Havenon A, Matouk C, Sheth K, Falcone G. COVID‐19 Infection Is Associated With Poor Outcomes in Patients With Intracerebral Hemorrhage. Journal Of The American Heart Association 2024, 13: e030999. PMID: 38293940, PMCID: PMC11056169, DOI: 10.1161/jaha.123.030999.
- Impact of Therapeutic Interventions on Cerebral Autoregulatory Function Following Severe Traumatic Brain Injury: A Secondary Analysis of the BOOST-II StudyPrasad A, Gilmore E, Kim J, Begunova L, Olexa M, Beekman R, Falcone G, Matouk C, Ortega-Gutierrez S, Temkin N, Barber J, Diaz-Arrastia R, de Havenon A, Petersen N. Impact of Therapeutic Interventions on Cerebral Autoregulatory Function Following Severe Traumatic Brain Injury: A Secondary Analysis of the BOOST-II Study. Neurocritical Care 2023, 1-9. PMID: 38158481, DOI: 10.1007/s12028-023-01896-x.
- Comparative Outcomes of Mechanical Thrombectomy in Acute Ischemic Stroke Patients with ASPECTS 2-3 vs. 4-5Orscelik A, Matsukawa H, Elawady S, Sowlat M, Cunningham C, Zandpazandi S, Kasem R, Maier I, Jabbour P, Kim J, Wolfe S, Rai A, Starke R, Psychogios M, Shaban A, Goyal N, Yoshimura S, Cuellar H, Howard B, Alawieh A, Romano D, Tanweer O, Mascitelli J, Fragata I, Polifka A, Osbun J, Crosa R, Matouk C, Park M, Levitt M, Brinjikji W, Moss M, Dumont T, Williamson R, Navia P, Kan P, De Leacy R, Chowdhry S, Ezzeldin M, Spiotta A, Al Kasab S, Collaborators S. Comparative Outcomes of Mechanical Thrombectomy in Acute Ischemic Stroke Patients with ASPECTS 2-3 vs. 4-5. Journal Of Stroke And Cerebrovascular Diseases 2023, 33: 107528. PMID: 38134550, DOI: 10.1016/j.jstrokecerebrovasdis.2023.107528.
- Successful mechanical thrombectomy for terminal ICA bullet embolism: A case report.Clouse J, Thaci B, Clark A, Baggett M, Raslan O, Matouk C, Waldau B, Cord B. Successful mechanical thrombectomy for terminal ICA bullet embolism: A case report. Interventional Neuroradiology 2023, 15910199231219021. PMID: 38073079, DOI: 10.1177/15910199231219021.
- Comprehensive analysis of the impact of procedure time and the ‘golden hour’ in subpopulations of stroke thrombectomy patientsAsh M, Dimisko L, Chalhoub R, Howard B, Cawley C, Matouk C, Pabaney A, Spiotta A, Jabbour P, Maier I, Wolfe S, T A, Kim J, Psychogios M, Mascitelli J, Starke R, Shaban A, Yoshimura S, De Leacy R, Kan P, Fragata I, Polifka A, Arthur A, Park M, Crosa R, Williamson R, Dumont T, Levitt M, Al Kasab S, Tjoumakaris S, Liman J, Saad H, Samaniego E, Fargen K, Grossberg J, Alawieh A. Comprehensive analysis of the impact of procedure time and the ‘golden hour’ in subpopulations of stroke thrombectomy patients. Journal Of NeuroInterventional Surgery 2023, jnis-2023-020792. PMID: 37875342, DOI: 10.1136/jnis-2023-020792.
- Detection of Intracerebral Hemorrhage Using Low-Field, Portable Magnetic Resonance Imaging in Patients With StrokeMazurek M, Parasuram N, Peng T, Beekman R, Yadlapalli V, Sorby-Adams A, Lalwani D, Zabinska J, Gilmore E, Petersen N, Falcone G, Sujijantarat N, Matouk C, Payabvash S, Sze G, Schiff S, Iglesias J, Rosen M, de Havenon A, Kimberly W, Sheth K. Detection of Intracerebral Hemorrhage Using Low-Field, Portable Magnetic Resonance Imaging in Patients With Stroke. Stroke 2023, 54: 2832-2841. PMID: 37795593, PMCID: PMC11103256, DOI: 10.1161/strokeaha.123.043146.
- P117/179 Treatment of normal pressure hydrocephalus using the eShunt endovascular transvenous implantPedro L, Matouk C, Siddiqui A, Lylyk I, Bleise C, Scrivano E, Lylyk P, Joseph A, Brandon B, Elad L, Heilman C, Malek A. P117/179 Treatment of normal pressure hydrocephalus using the eShunt endovascular transvenous implant. 2023, a59.3-a60. DOI: 10.1136/jnis-2023-esmint.146.
- The Impact of Dual Antiplatelet Therapy Duration on Unruptured Aneurysm Occlusion After Flow Diversion: A Multicenter StudyVranic J, Harker P, Stapleton C, Regenhardt R, Dmytriw A, Doron O, Alotaibi N, Leslie-Mazwi T, Gupta R, Berglar I, Tan C, Koch M, Raymond S, Mascitelli J, Patterson T, Seinfeld J, White A, Case D, Roark C, Gandhi C, Al-Mufti F, Cooper J, Matouk C, Sujijantarat N, Devia D, Ocampo-Navia M, Villamizar-Torres D, Puentes J, Patel A. The Impact of Dual Antiplatelet Therapy Duration on Unruptured Aneurysm Occlusion After Flow Diversion: A Multicenter Study. Journal Of Computer Assisted Tomography 2023, 47: 753-758. PMID: 37707405, DOI: 10.1097/rct.0000000000001457.
- O-039 Preliminary results of the cerevasc eShunt implant in the treatment of normal pressure hydrocephalusLylyk P, Matouk C, Siddiqui A, Lylyk I, Bleise C, Scrivano E, Lylyk N, Antonios J, Beneduce B, Levy E, Heilman C, Malek A. O-039 Preliminary results of the cerevasc eShunt implant in the treatment of normal pressure hydrocephalus. 2023, a31-a32. DOI: 10.1136/jnis-2023-snis.39.
- O-068 Regulatory B cell and adjunctive immune population drives intracranial aneurysm rupture in patient populationAntonios J, Barak T, Gultekin B, Yalcin K, Chamberlain A, Hebert R, Matouk C, Gunel M. O-068 Regulatory B cell and adjunctive immune population drives intracranial aneurysm rupture in patient population. 2023, a53.1-a53. DOI: 10.1136/jnis-2023-snis.68.
- Predictors of Angiographic Outcome After Failed Thrombectomy for Large Vessel Occlusion: Insights from the Stroke Thrombectomy and Aneurysm RegistryWebb M, Essibayi M, Al Kasab S, Maier I, Psychogios M, Grossberg J, Alawieh A, Wolfe S, Arthur A, Dumont T, Kan P, Kim J, De Leacy R, Osbun J, Rai A, Jabbour P, Park M, Crosa R, Levitt M, Polifka A, Yoshimura S, Matouk C, Williamson R, Fragata I, Chowdhry S, Starke R, Samaniego E, Cuellar H, Spiotta A, Mascitelli J. Predictors of Angiographic Outcome After Failed Thrombectomy for Large Vessel Occlusion: Insights from the Stroke Thrombectomy and Aneurysm Registry. Neurosurgery 2023, 93: 1168-1179. PMID: 37377425, DOI: 10.1227/neu.0000000000002560.
- Higher Hospital Frailty Risk Score Is Associated With Increased Risk of Stroke: Observational and Genetic AnalysesRenedo D, Acosta J, Koo A, Rivier C, Sujijantarat N, de Havenon A, Sharma R, Gill T, Sheth K, Falcone G, Matouk C. Higher Hospital Frailty Risk Score Is Associated With Increased Risk of Stroke: Observational and Genetic Analyses. Stroke 2023, 54: 1538-1547. PMID: 37216451, PMCID: PMC10212531, DOI: 10.1161/strokeaha.122.041891.
- Investigating the Relationship Between Oximetry Trends During Endovascular Therapy and Neurological Worsening for Patients with Acute Ischemic Stroke (S24.006)Olexa M, Begunova Y, Bartolome D, Peng T, Matouk C, Sheth K, Petersen N. Investigating the Relationship Between Oximetry Trends During Endovascular Therapy and Neurological Worsening for Patients with Acute Ischemic Stroke (S24.006). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000202997.
- Teaching NeuroImages: Susceptibility-weighted MRIKalra V, Malhotra A, Matouk C. Teaching NeuroImages: Susceptibility-weighted MRI. Neurology 2023, 100: s250-s250. DOI: 10.1212/wnl.0000000000207035.
- 482 Triple Therapy Versus Dual Antiplatelet Therapy for Dolichoectatic Vertebrobasilar Fusiform Aneurysms Treated With Flow Diverters: The Last Frontier?Siddiqui A, Monteiro A, Hanel R, Kan P, Mohanty A, Cortez G, Rabinovich M, Matouk C, Sujijantarat N, Romero C, Stone J, Ebersole K, Fry L, Natarajan S, Thomson B, Ortega-Gutierrez S, Vivanco-Suarez J, Wakhloo A, Levy E. 482 Triple Therapy Versus Dual Antiplatelet Therapy for Dolichoectatic Vertebrobasilar Fusiform Aneurysms Treated With Flow Diverters: The Last Frontier? Neurosurgery 2023, 69: 103-104. DOI: 10.1227/neu.0000000000002375_482.
- 472 Low-Field Portable Magnetic Resonance Imaging for Bedside Evaluation of Ischemic Stroke in Post-Thrombectomy PatientsSujijantarat N, Koo A, Jambour I, Malhotra A, Crawford A, Mazurek M, Parasuram N, Chavva I, Sze G, Renado D, Antonios J, Elsamadicy A, Hebert R, Petersen N, Sheth K, Matouk C. 472 Low-Field Portable Magnetic Resonance Imaging for Bedside Evaluation of Ischemic Stroke in Post-Thrombectomy Patients. Neurosurgery 2023, 69: 100-100. DOI: 10.1227/neu.0000000000002375_472.
- 550 Hospital Frailty Risk Score is an Independent Risk Factor for VP Shunt Placement for Ruptured Intracranial AneurysmsKoo A, Elsamadicy A, Sarkozy M, Reeves B, Craft S, Sherman J, Sayeed S, Antonios J, Renedo D, Sujijantarat N, Hebert R, Malhotra A, Matouk C. 550 Hospital Frailty Risk Score is an Independent Risk Factor for VP Shunt Placement for Ruptured Intracranial Aneurysms. Neurosurgery 2023, 69: 120-120. DOI: 10.1227/neu.0000000000002375_550.
- Malpractice Litigation Related to Diagnosis and Treatment of Intracranial AneurysmsKhan A, Khunte M, Wu X, Bajaj S, Payabvash S, Wintermark M, Matouk C, Seidenwurm D, Gandhi D, Parizel P, Mezrich J, Malhotra A. Malpractice Litigation Related to Diagnosis and Treatment of Intracranial Aneurysms. American Journal Of Neuroradiology 2023, 44: 460-466. PMID: 36997286, PMCID: PMC10084911, DOI: 10.3174/ajnr.a7828.
- Vascular steal and associated intratumoral aneurysms in highly vascular brain tumors: illustrative caseHong C, Marianayagam N, Morales-Valero S, Barak T, Tabor J, O’Brien J, Huttner A, Baehring J, Gunel M, Erson-Omay E, Fulbright R, Matouk C, Moliterno J. Vascular steal and associated intratumoral aneurysms in highly vascular brain tumors: illustrative case. Journal Of Neurosurgery Case Lessons 2023, 5: case22512. PMID: 36880509, PMCID: PMC10550659, DOI: 10.3171/case22512.
- Emergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfaAmmar A, Elsamadicy A, Ammar M, Reeves B, Koo A, Falcone G, Hwang D, Petersen N, Kim J, Beekman R, Prust M, Magid-Bernstein J, Acosta J, Herbert R, Sheth K, Matouk C, Gilmore E. Emergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfa. Clinical Neurology And Neurosurgery 2023, 226: 107621. PMID: 36791588, DOI: 10.1016/j.clineuro.2023.107621.
- Abstract 11: Identifiable Patterns Of Noninvasive Cerebral Oximetry During Endovascular Therapy For Acute Ischemic Stroke Are Associated With Neurological DeteriorationOlexa M, Begunova Y, Bartolome D, Peng T, Sheth K, Matouk C, Petersen N. Abstract 11: Identifiable Patterns Of Noninvasive Cerebral Oximetry During Endovascular Therapy For Acute Ischemic Stroke Are Associated With Neurological Deterioration. Stroke 2023, 54: a11-a11. DOI: 10.1161/str.54.suppl_1.11.
- Abstract 9: Autoregulation-based Blood Pressure Targets After Endovascular ThrombectomyPetersen N, Begunova Y, Olexa M, Bartolome D, Kumar A, Chen Y, Dhar R, Peng T, Ortega-Gutierrez S, Falcone G, gilmore E, Kim J, Schindler J, Sansing L, Matouk C, Sheth K. Abstract 9: Autoregulation-based Blood Pressure Targets After Endovascular Thrombectomy. Stroke 2023, 54: a9-a9. DOI: 10.1161/str.54.suppl_1.9.
- Abstract WP130: Intracerebral Hemorrhage Outcomes And Trends During The Covid-19 Pandemic. An Observational Study Of 61,417 Cases.Renedo D, Leasure A, Acosta J, Young R, Alhanti B, Mac Grory B, Spudich S, Messe S, Reeves M, Hassan A, Schwamm L, Matouk C, Sheth K, Falcone G. Abstract WP130: Intracerebral Hemorrhage Outcomes And Trends During The Covid-19 Pandemic. An Observational Study Of 61,417 Cases. Stroke 2023, 54: awp130-awp130. DOI: 10.1161/str.54.suppl_1.wp130.
- Abstract WMP75: Community Deprivation And Healthcare Access/Utilization In Patients With Carotid Stenosis: Results From The All Of UsResearch ProgramClocchiatti-Tuozzo S, Renedo D, Rivier C, Lopez V, Matouk C, Sheth K, Gill T, Falcone G. Abstract WMP75: Community Deprivation And Healthcare Access/Utilization In Patients With Carotid Stenosis: Results From The All Of UsResearch Program. Stroke 2023, 54: awmp75-awmp75. DOI: 10.1161/str.54.suppl_1.wmp75.
- Abstract HUP6: Community Deprivation And Healthcare Access/Utilization In Patients With Carotid Stenosis: Results From The All Of Us Research ProgramClocchiatti-Tuozzo S, Renedo D, Rivier C, Lopez V, Matouk C, Sheth K, Gill T, Falcone G. Abstract HUP6: Community Deprivation And Healthcare Access/Utilization In Patients With Carotid Stenosis: Results From The All Of Us Research Program. Stroke 2023, 54: ahup6-ahup6. DOI: 10.1161/str.54.suppl_1.hup6.
- Abstract 51: Apoe Epsilon 4 And Risk Of Bleeding Patients With Brain Arteriovenous Malformations. A Combined Genetic Study In The Uk Biobank And All Of UsRenedo D, Rivier C, Acosta J, Clocchiatti S, Wu K, Torres-Lopez V, Sheth K, Gunel M, Matouk C, Falcone G. Abstract 51: Apoe Epsilon 4 And Risk Of Bleeding Patients With Brain Arteriovenous Malformations. A Combined Genetic Study In The Uk Biobank And All Of Us. Stroke 2023, 54: a51-a51. DOI: 10.1161/str.54.suppl_1.51.
- Abstract 15: Single-cell Immune Landscape Of Human Clot Retrieved At Mechanical Thrombectomy. Association With Stroke Origin.Renedo D, Sujijantarat N, Antonios J, Koo A, Acosta J, Falcone G, Hebert R, Sansing L, Navaratnam D, Matouk C. Abstract 15: Single-cell Immune Landscape Of Human Clot Retrieved At Mechanical Thrombectomy. Association With Stroke Origin. Stroke 2023, 54: a15-a15. DOI: 10.1161/str.54.suppl_1.15.
- Abstract WP154: Low-field Portable Mri For Routine Post-thrombectomy Assessment Of Ongoing Brain InjurySujijantarat N, Koo A, Jambor I, Malhotra A, Crawford A, Mazurek M, Parasuram N, Yadlapalli V, Chavva I, Antonios J, Elsamadicy A, Renedo D, Hebert R, Schindler J, Sansing L, De Havenon A, Olexa M, Iglesias J, Rosen M, Kimberly W, Petersen N, Sheth K, Matouk C. Abstract WP154: Low-field Portable Mri For Routine Post-thrombectomy Assessment Of Ongoing Brain Injury. Stroke 2023, 54: awp154-awp154. DOI: 10.1161/str.54.suppl_1.wp154.
- Future of Neurology & Technology: Neuroimaging Made Accessible Using Low-Field, Portable MRIParasuram N, Crawford A, Mazurek M, Chavva I, Beekman R, Gilmore E, Petersen N, Payabvash S, Sze G, Eugenio Iglesias J, Omay S, Matouk C, Longbrake E, de Havenon A, Schiff S, Rosen M, Kimberly W, Sheth K. Future of Neurology & Technology: Neuroimaging Made Accessible Using Low-Field, Portable MRI. Neurology 2023, 100: 1067-1071. PMID: 36720639, PMCID: PMC10259275, DOI: 10.1212/wnl.0000000000207074.
- In Reply to the Letter to Editor Regarding "Hospital Frailty Risk Score Predicts Adverse Events and Readmission Following Ventriculoperitoneal Shunt Surgery for Normal Pressure Hydrocephalus"Koo A, Elsamadicy A, Matouk C. In Reply to the Letter to Editor Regarding "Hospital Frailty Risk Score Predicts Adverse Events and Readmission Following Ventriculoperitoneal Shunt Surgery for Normal Pressure Hydrocephalus". World Neurosurgery 2023, 169: 124. PMID: 36585096, DOI: 10.1016/j.wneu.2022.11.023.
- Response to letter to the Editor on ‘Utility of the Hospital Frailty Risk Score in patients undergoing endovascular treatment for ruptured aneurysms’Koo A, Elsamadicy A, Renedo D, Matouk C. Response to letter to the Editor on ‘Utility of the Hospital Frailty Risk Score in patients undergoing endovascular treatment for ruptured aneurysms’. Journal Of NeuroInterventional Surgery 2022, 15: 307-308. PMID: 36319084, DOI: 10.1136/jnis-2022-019708.
- Unrepaired Maternal Vein of Galen Malformation in Pregnancy: A Case ReportAckerman-Banks C, Fardelmann K, Lam D, Simmons M, Elder R, Matouk C, Campbell K. Unrepaired Maternal Vein of Galen Malformation in Pregnancy: A Case Report. A&A Practice 2022, 16: e01634. PMID: 36599040, DOI: 10.1213/xaa.0000000000001634.
- P-017 Triple therapy versus dual antiplatelet therapy for dolichoectatic vertebrobasilar fusiform aneurysms treated with flow-diverters: the last frontier?Siddiqui A, Monteiro A, Hanel R, Kan P, Mohanty A, Cortez G, Rabinovich M, Matouk C, Sujijantarat N, Ebersole K, Fry L, Natarajan S, Owusu-Adjei B, Ortega-Gutierrez S, Vivanco-Suarez J, Wakhloo A, Levy E. P-017 Triple therapy versus dual antiplatelet therapy for dolichoectatic vertebrobasilar fusiform aneurysms treated with flow-diverters: the last frontier? 2022, a59.1-a59. DOI: 10.1136/neurintsurg-2022-snis.89.
- Impaired Cerebral Autoregulation Related Blood Pressure Reductions After Nimodipine Are Associated with Ischemic Changes on EEG After Subarachnoid Hemorrhage (P13-10.002)Top I, Chen Y, Bartolome D, Rapuano A, Gilmore E, Sheth K, Matouk C, Petersen N, Kim J. Impaired Cerebral Autoregulation Related Blood Pressure Reductions After Nimodipine Are Associated with Ischemic Changes on EEG After Subarachnoid Hemorrhage (P13-10.002). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.3539.
- Cerebral Autoregulatory Function Before, During, and After Therapeutic Interventions Following Severe Traumatic Brain Injury: A Secondary Analysis of the BOOST-II Study (S21.001)Prasad A, Kobsa J, Soto A, Bartolome D, Begunova L, Kim J, Gilmore E, Sheth K, Matouk C, De Havenon A, Diaz-Arrastia R, Petersen N. Cerebral Autoregulatory Function Before, During, and After Therapeutic Interventions Following Severe Traumatic Brain Injury: A Secondary Analysis of the BOOST-II Study (S21.001). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.557.
- Poor Collaterals and Rapid Early Infarct Progression Are Associated With Increased Vulnerability to Blood Pressure Reductions (S21.002)Begunova Y, Bartolome D, Kobsa J, Soto A, Prasad A, Galecio M, Vivanco-Suarez J, Quispe-Orozco D, Farooqui M, Sansing L, Schindler J, De Havenon A, Matouk C, Sheth K, Ortega-Gutierrez S, Petersen N. Poor Collaterals and Rapid Early Infarct Progression Are Associated With Increased Vulnerability to Blood Pressure Reductions (S21.002). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.3104.
- Cerebral hypoperfusion after nimodipine administration is associated with worse functional outcomes in subarachnoid hemorrhage patients (P6-7.001)Bartolome D, Begunova Y, Prasad A, Soto A, Kobsa J, Top I, Quispe-Orozco D, Farooqui M, Zevallos C, Kim J, Gilmore E, Beekman R, De Havenon A, Matouk C, Sheth K, Ortega-Gutiérrez S, Petersen N. Cerebral hypoperfusion after nimodipine administration is associated with worse functional outcomes in subarachnoid hemorrhage patients (P6-7.001). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.3609.
- 307 The Hospital Frailty Risk Score Independently Predicts Increased Complication Rates and Healthcare Resource Utilization After Endovascular Treatment of Ruptured AneurysmsKoo A, Elsamadicy A, Sarkozy M, Sherman J, Reeves B, Freedman I, Antonios J, Sujijantarat N, Renado D, Hebert R, Malhotra A, Matouk C. 307 The Hospital Frailty Risk Score Independently Predicts Increased Complication Rates and Healthcare Resource Utilization After Endovascular Treatment of Ruptured Aneurysms. Neurosurgery 2022, 68: 67-68. DOI: 10.1227/neu.0000000000001880_307.
- Abstract WP111: Deployment Of Portable, Bedside, Low-field Magnetic Resonance Imaging In The Emergency Department To Evaluate Patients With Acute StrokeChavva I, Mazurek M, Yuen M, Prabhat A, Crawford A, Cahn B, Schindler J, Sansing L, Matouk C, Hebert R, de Havenon A, Sharma R, Payabvash S, Sze G, Aydin A, Parwani V, Ulrich A, Brown K, Sheth K, Wira C. Abstract WP111: Deployment Of Portable, Bedside, Low-field Magnetic Resonance Imaging In The Emergency Department To Evaluate Patients With Acute Stroke. Stroke 2022, 53: awp111-awp111. DOI: 10.1161/str.53.suppl_1.wp111.
- Abstract 105: Polygenic Burden Of Hypertension-related Alleles Leads To Non-traumatic Subarachnoid Hemorrhage At Younger AgesVanent K, Acosta J, Both C, Leasure A, Noche R, Levitt M, Matouk C, Gunel M, Sheth K, Falcone G. Abstract 105: Polygenic Burden Of Hypertension-related Alleles Leads To Non-traumatic Subarachnoid Hemorrhage At Younger Ages. Stroke 2022, 53: a105-a105. DOI: 10.1161/str.53.suppl_1.105.
- Abstract TP134: Association Of Neutrophil-lymphocyte Ratio With Functional Outcome In Spontaneous Intracerebral HemorrhageAtillasoy J, Leasure A, Schwartz A, Reznik M, Moody S, Bevers M, Matouk C, Falcone G, Sansing L, Kimberly W, Sheth K. Abstract TP134: Association Of Neutrophil-lymphocyte Ratio With Functional Outcome In Spontaneous Intracerebral Hemorrhage. Stroke 2022, 53: atp134-atp134. DOI: 10.1161/str.53.suppl_1.tp134.
- Abstract 123: Carotid Artery Stenosis In Underrepresented Populations Defined By Factors Other Than Race/ethnicity: Results From All Of UsRenedo D, Acosta J, Sheth K, Matouk C, Falcone G. Abstract 123: Carotid Artery Stenosis In Underrepresented Populations Defined By Factors Other Than Race/ethnicity: Results From All Of Us. Stroke 2022, 53: a123-a123. DOI: 10.1161/str.53.suppl_1.123.
- Abstract 99: Single Cell RNA-Sequencing Reveals Array Of Immune Activation States In Intracerebral HemorrhageJohnson C, Askenase M, Beatty H, DeLong J, Zhang L, Sheth K, Cord B, Hebert R, Matouk C, Sansing L. Abstract 99: Single Cell RNA-Sequencing Reveals Array Of Immune Activation States In Intracerebral Hemorrhage. Stroke 2022, 53: a99-a99. DOI: 10.1161/str.53.suppl_1.99.
- Abstract 91: Large Vessel Occlusion Stroke Patients With Rapid Early Infarct Progression And Poor Collaterals Are Vulnerable To Blood Pressure ReductionsBegunova Y, Bartolome D, Kobsa J, Prasad A, Soto A, Quispe-Orozco D, Farooqui M, Zevallos C, Sansing L, Schindler J, De Havenon A, Matouk C, Sheth K, Ortega-Gutierrez S, Petersen N. Abstract 91: Large Vessel Occlusion Stroke Patients With Rapid Early Infarct Progression And Poor Collaterals Are Vulnerable To Blood Pressure Reductions. Stroke 2022, 53: a91-a91. DOI: 10.1161/str.53.suppl_1.91.
- Abstract TMP55: Post-stroke Blood Pressure Variability In The Acute Phase Is Associated With Pre-stroke Blood Pressure Variability In Patients Undergoing Mechanical ThrombectomySoto A, Prasad A, Kobsa J, Bartolome D, Begunova Y, Kodali S, Quispe-Orozco D, Farooqui M, Zevallos C, Sansing L, Schindler J, Matouk C, Sheth K, de Havenon A, Ortega-Gutierrez S, Petersen N. Abstract TMP55: Post-stroke Blood Pressure Variability In The Acute Phase Is Associated With Pre-stroke Blood Pressure Variability In Patients Undergoing Mechanical Thrombectomy. Stroke 2022, 53: atmp55-atmp55. DOI: 10.1161/str.53.suppl_1.tmp55.
- Abstract 89: Nimodipine-induced Blood Pressure Reductions Below Personalized Limits Of Autoregulation Are Associated With Worse Outcomes After Subarachnoid HemorrhageBartolome D, Begunova Y, Prasad A, Soto A, Kobsa J, Top I, Quispe-Orozco D, Farooqui M, Zevallos C, Kim J, Gilmore E, Beekman R, de Havenon A, Matouk C, Sheth K, Ortega-Gutierrez S, Petersen N. Abstract 89: Nimodipine-induced Blood Pressure Reductions Below Personalized Limits Of Autoregulation Are Associated With Worse Outcomes After Subarachnoid Hemorrhage. Stroke 2022, 53: a89-a89. DOI: 10.1161/str.53.suppl_1.89.
- Abstract 1122‐000141: Initial Experience of Using a Large‐Bore (0.096” Inner Diameter) Access Catheter in Neurovascular InterventionsSchirmer C, Matouk C, Hassan A, Siddiqui A, Tomalty R, Frei D. Abstract 1122‐000141: Initial Experience of Using a Large‐Bore (0.096” Inner Diameter) Access Catheter in Neurovascular Interventions. Stroke Vascular And Interventional Neurology 2021, 1 DOI: 10.1161/svin.01.suppl_1.000141.
- Hybernia post-mechanical thrombectomy – Endovascular cerebral hypothermia trial in acute ischemic stroke (post-mtech trial)Choi J, Saver J, Nogueira R, Poli S, Nguyen T, Chen M, Matouk C, Pile-Spellman J. Hybernia post-mechanical thrombectomy – Endovascular cerebral hypothermia trial in acute ischemic stroke (post-mtech trial). Journal Of The Neurological Sciences 2021, 429: 119718. DOI: 10.1016/j.jns.2021.119718.
- Drip-and-ship versus mothership for endovascular treatment of acute stroke: A comparative effectiveness analysisWu X, Wira C, Matouk C, Forman H, Gandhi D, Sanelli P, Schindler J, Malhotra A. Drip-and-ship versus mothership for endovascular treatment of acute stroke: A comparative effectiveness analysis. International Journal Of Stroke 2021, 17: 315-322. PMID: 33759645, DOI: 10.1177/17474930211008701.
- Klotho-VS Heterozygosity is Associated with Lower Risk of Non-traumatic Subarachnoid Hemorrhage (2737)Acosta J, Szejko N, Lopez V, Both C, Sansing L, Sheth K, Matouk C, Falcone G. Klotho-VS Heterozygosity is Associated with Lower Risk of Non-traumatic Subarachnoid Hemorrhage (2737). Neurology 2021, 96 DOI: 10.1212/wnl.96.15_supplement.2737.
- Prehospital Blood Pressure Reductions Are Associated with Neurologic Worsening in Patients With Large-vessel Occlusion Stroke (2844)Kobsa J, Prasad A, Soto A, Kodali S, Nguyen C, Peshwe K, Orozco D, Farooqui M, Zevallos C, Sansing L, Schindler J, Matouk C, Sheth K, Ortega-Gutierrez S, Petersen N. Prehospital Blood Pressure Reductions Are Associated with Neurologic Worsening in Patients With Large-vessel Occlusion Stroke (2844). Neurology 2021, 96 DOI: 10.1212/wnl.96.15_supplement.2844.
- Blood Pressure Reductions in the Hyperacute Phase of Large Vessel Occlusion Ischemic Stroke Are Associated With Infarct Progression And Poor Functional Outcome (5141)Peshwe K, Nguyen C, Kodali S, Kobsa J, Prasad A, Soto A, Wira C, Matouk C, Sheth K, Petersen N. Blood Pressure Reductions in the Hyperacute Phase of Large Vessel Occlusion Ischemic Stroke Are Associated With Infarct Progression And Poor Functional Outcome (5141). Neurology 2021, 96 DOI: 10.1212/wnl.96.15_supplement.5141.
- Ischemic Stroke, Inflammation, and Endotheliopathy in COVID-19 Patients (2402)McAlpine L, Zubair A, Maran I, Chojecka P, Lleva P, Jasne A, Navaratnam D, Matouk C, Schindler J, Chun H, Lee A, Spudich S, Sharma R, Sansing L. Ischemic Stroke, Inflammation, and Endotheliopathy in COVID-19 Patients (2402). Neurology 2021, 96 DOI: 10.1212/wnl.96.15_supplement.2402.
- Abstract P510: Ct Angiographic Radiomics Signature Predicts Functional Outcome Following Endovascular Thrombectomy in Large Vessel Occlusion StrokeAvery E, Behland J, Haider S, Zeevi T, Nguyen C, Peshwe K, Petersen N, Falcone G, Sansing L, Malhotra A, Matouk C, Sheth K, Payabvash S. Abstract P510: Ct Angiographic Radiomics Signature Predicts Functional Outcome Following Endovascular Thrombectomy in Large Vessel Occlusion Stroke. Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p510.
- Abstract P412: Klotho -vS Heterozygosity is Associated With Lower Risk of Non-Traumatic Subarachnoid HemorrhageAcosta J, Szejko N, Torres Lopez V, Both C, Sansing L, Sheth K, Matouk C, Gunel M, Falcone G. Abstract P412: Klotho -vS Heterozygosity is Associated With Lower Risk of Non-Traumatic Subarachnoid Hemorrhage. Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p412.
- Abstract P410: Association of Serum GFAP With Hematoma Expansion and Poor Outcome After Intracerebral Hemorrhage: The Factor VII for ICH TrialLeasure A, Vanent K, Bevers M, Kimberly W, Mayer S, Steiner T, Matouk C, Sansing L, Falcone G, Sheth K. Abstract P410: Association of Serum GFAP With Hematoma Expansion and Poor Outcome After Intracerebral Hemorrhage: The Factor VII for ICH Trial. Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p410.
- Abstract MP36: Blood Pressure Reductions in the Hyperacute Phase of Large Vessel Occlusion Ischemic Stroke Are Associated With Infarct Progression and Poor Functional OutcomePeshwe K, Nguyen C, Kodali S, Kobsa J, Prasad A, Soto A, Wira C, Matouk C, Sheth K, Petersen N. Abstract MP36: Blood Pressure Reductions in the Hyperacute Phase of Large Vessel Occlusion Ischemic Stroke Are Associated With Infarct Progression and Poor Functional Outcome. Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.mp36.
- Abstract MP35: Blood Pressure Reductions Before Arrival at a Thrombectomy-Capable Hospital Are Associated With Neurologic Worsening in Patients With Large-Vessel OcclusionKobsa J, Prasad A, Soto A, Kodali S, Nguyen C, Peshwe K, Quispe-Orozco D, Farooqui M, Zeballos C, Sansing L, Schindler J, Matouk C, Sheth K, Ortega-Gutierrez S, Petersen N. Abstract MP35: Blood Pressure Reductions Before Arrival at a Thrombectomy-Capable Hospital Are Associated With Neurologic Worsening in Patients With Large-Vessel Occlusion. Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.mp35.
- Impact of Clot Location on Outcomes after Mechanical Thrombectomy for Anterior Circulation Acute Ischemic StrokeSujijantarat N, Koo A, Elsamadicy A, Hebert R, Cord B, Navaratnam D, Sansing L, Malhotra A, Matouk C. Impact of Clot Location on Outcomes after Mechanical Thrombectomy for Anterior Circulation Acute Ischemic Stroke. Neurosurgery 2020, 67 DOI: 10.1093/neuros/nyaa447_387.
- Predictors of Extended Length of Stay following Treatment of Unruptured Adult Cerebral AneurysmsKoo A, Elsamadicy A, Lin I, David W, Freedman I, Sujijantarat N, Cord B, Hebert R, Bahrassa F, Malhotra A, Matouk C. Predictors of Extended Length of Stay following Treatment of Unruptured Adult Cerebral Aneurysms. Neurosurgery 2020, 67 DOI: 10.1093/neuros/nyaa447_147.
- 30-Day Outcomes of Trans-Carotid Artery Revascularization with Proximal Protection Through ICA Flow Reversal in Neurosurgical PracticeCord B, Santarosa C, Sujijantarat N, Koo A, Elsamadicy A, Sheth K, Falcone G, Sansing L, Schindler J, Petersen N, Matouk C. 30-Day Outcomes of Trans-Carotid Artery Revascularization with Proximal Protection Through ICA Flow Reversal in Neurosurgical Practice. Neurosurgery 2020, 67 DOI: 10.1093/neuros/nyaa447_334.
- Patient Risk Factors Associated with 30- and 90- Day Readmission after Ventriculoperitoneal Shunt Placement for Idiopathic Normal Pressure Hydrocephalus in Elderly PatientsKoo A, Elsamadicy A, Lin I, David W, Reeves B, Santarosa C, Cord B, Malhotra A, Kahle K, Matouk C. Patient Risk Factors Associated with 30- and 90- Day Readmission after Ventriculoperitoneal Shunt Placement for Idiopathic Normal Pressure Hydrocephalus in Elderly Patients. Neurosurgery 2020, 67 DOI: 10.1093/neuros/nyaa447_202.
- Stem Cell Therapy for StrokeRobert S, Matouk C. Stem Cell Therapy for Stroke. 2020, 331-345. DOI: 10.1007/978-3-030-56954-9_15.
- Stereotactic Radiosurgery for Pediatric Arteriovenous Malformations: A Case Series Reflecting One Institution’s Experience With TreatmentChoi R, An Y, Aneja S, Bindra R, Bond J, Chiang V, Hansen J, Hebert R, Matouk C, Yu J. Stereotactic Radiosurgery for Pediatric Arteriovenous Malformations: A Case Series Reflecting One Institution’s Experience With Treatment. International Journal Of Radiation Oncology • Biology • Physics 2020, 108: e244. DOI: 10.1016/j.ijrobp.2020.07.589.
- Vascular Malformations of the Brain and SpineMatouk C, Cord B. Vascular Malformations of the Brain and Spine. 2020, 177-191. DOI: 10.1007/978-3-030-52552-1_14.
- Cerebral Autoregulation-guided Parameters for Predicting Midline Shift After Large-vessel Occlusion Ischemic Stroke (4253)Silverman A, Wang A, Kodali S, Strander S, Kimmel A, Nguyen C, Peshwe K, Matouk C, Sheth K, Marshall R, Tan C, Petersen N. Cerebral Autoregulation-guided Parameters for Predicting Midline Shift After Large-vessel Occlusion Ischemic Stroke (4253). Neurology 2020, 94 DOI: 10.1212/wnl.94.15_supplement.4253.
- Characterization of Blood Pressure Trajectories in the Hyperacute Phase of Large Vessel Occlusion Ischemic Stroke (4507)Peshwe K, Nguyen C, Kodali S, Strander S, Kimmel A, Wang A, Matouk C, Sansing L, Sheth K, Wira C, Silverman A, Petersen N. Characterization of Blood Pressure Trajectories in the Hyperacute Phase of Large Vessel Occlusion Ischemic Stroke (4507). Neurology 2020, 94 DOI: 10.1212/wnl.94.15_supplement.4507.
- Improving the Safety of Neurocritical Care Transitions through Failure Mode and Effects Analysis (FMEA) (5300)Chilakamarri P, Finn E, Sather J, Sheth K, Matouk C, Parwani V, Ulrich A, Davis M, Pham L, Chaudhry S, Venkatesh A. Improving the Safety of Neurocritical Care Transitions through Failure Mode and Effects Analysis (FMEA) (5300). Neurology 2020, 94 DOI: 10.1212/wnl.94.15_supplement.5300.
- Blood Pressure Decreases Occur Throughout Endovascular Thrombectomy and Are Associated with Poor Functional Outcome (4872)Kimmel A, Silverman A, Kodali S, Strander S, Nguyen C, Peshwe K, Wang A, Cardenas G, Holcombe A, Zevallos C, Dandapat S, Sansing L, Schindler J, Falcone G, Matouk C, Sheth K, Ortega-Gutierrez S, Petersen N. Blood Pressure Decreases Occur Throughout Endovascular Thrombectomy and Are Associated with Poor Functional Outcome (4872). Neurology 2020, 94 DOI: 10.1212/wnl.94.15_supplement.4872.
- Causes of Death in a Longitudinal Analysis of Spontaneous Intracerebral Hemorrhage Survivors (4228)Kuohn L, Leasure A, Acosta J, Vanent K, Murthy S, Kamel H, Matouk C, Sansing L, Falcone G, Sheth K. Causes of Death in a Longitudinal Analysis of Spontaneous Intracerebral Hemorrhage Survivors (4228). Neurology 2020, 94 DOI: 10.1212/wnl.94.15_supplement.4228.
- Deployment of Portable, Bedside, Low-field Magnetic Resonance Imaging for Evaluation of Stroke Patients (272)Cahn B, Shah J, Dyvorne H, O’Halloran R, Poole M, Yuen M, Mazurek M, Ward A, Payabvash S, Beekman R, Brown S, Falcone G, Gobeske K, Petersen N, Jasne A, Sharma R, Schindler J, Sansing L, Gilmore E, Wira C, Matouk C, Sze G, Rosen M, Kimberly W, Sheth K. Deployment of Portable, Bedside, Low-field Magnetic Resonance Imaging for Evaluation of Stroke Patients (272). Neurology 2020, 94 DOI: 10.1212/wnl.94.15_supplement.272.
- Risk of Worse Outcome in Stroke Patients with High Blood Pressure Variability After Endovascular Thrombectomy May Be Amplified by Impaired Cerebral Autoregulation (4457)Nguyen C, Silverman A, Wang A, Kodali S, Strander S, Kimmel A, Peshwe K, de Havenon A, Gilmore E, Sansing L, Schindler J, Matouk C, Sheth K, Petersen N. Risk of Worse Outcome in Stroke Patients with High Blood Pressure Variability After Endovascular Thrombectomy May Be Amplified by Impaired Cerebral Autoregulation (4457). Neurology 2020, 94 DOI: 10.1212/wnl.94.15_supplement.4457.
- Abstract WP410: Hemoglobin Levels and Poor Outcome in Intracerebral Hemorrhage: An Exploratory Analysis of Individual Patient Data Across Multiple StudiesAcosta J, Leasure A, Kuohn L, Petersen N, Sansing L, Matouk C, Testai F, Langefeld C, Woo D, Qureshi A, Mayer S, Sheth K, Falcone G. Abstract WP410: Hemoglobin Levels and Poor Outcome in Intracerebral Hemorrhage: An Exploratory Analysis of Individual Patient Data Across Multiple Studies. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wp410.
- Abstract WP11: Timing of Blood Pressure Decreases During Mechanical Thrombectomy for Ischemic StrokeKimmel A, Silverman A, Kodali S, Strander S, Nguyen C, Peshwe K, Wang A, Lopez G, Holcombe A, Zevallos C, Dandapat S, Sansing L, Schindler J, Falcone G, Matouk C, Sheth K, Ortega-Gutiérrez S, Petersen N. Abstract WP11: Timing of Blood Pressure Decreases During Mechanical Thrombectomy for Ischemic Stroke. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wp11.
- Abstract WMP101: Prediction of Clinical Outcome in Supratentorial Intracerebral Hemorrhage: Application of Baseline Ct Scan Radiomics Feature Extraction and Machine Learning ClassifiersPayabvash S, Acosta J, Haider S, Noche R, Kirsch E, Matouk C, Sansing L, Sheth K, Falcone G. Abstract WMP101: Prediction of Clinical Outcome in Supratentorial Intracerebral Hemorrhage: Application of Baseline Ct Scan Radiomics Feature Extraction and Machine Learning Classifiers. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wmp101.
- Abstract 71: Sex and Genetic Predisposition Synergistically Influence Risk of Stroke and Myocardial Infarction in Middle-Aged Persons Without Risk FactorsFalcone G, Acosta J, Leasure A, Vanent K, Noche R, Kirsch E, Petersen N, Schindler J, Sansing L, Gill T, Matouk C, Gunel M, Sheth K. Abstract 71: Sex and Genetic Predisposition Synergistically Influence Risk of Stroke and Myocardial Infarction in Middle-Aged Persons Without Risk Factors. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.71.
- Abstract 66: Causal Associations Between Genetically-determined Smoking and Risk of Subarachnoid HemorrhageAcosta J, Both C, Brown S, Leasure A, Vanent K, Noche R, Kirsch E, Petersen N, Matouk C, Gunel M, Gill T, Sheth K, Falcone G. Abstract 66: Causal Associations Between Genetically-determined Smoking and Risk of Subarachnoid Hemorrhage. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.66.
- Abstract 57: Deployment of Portable, Bedside, Low-Field Magnetic Resonance Imaging for Evaluation of Stroke PatientsCahn B, Shah J, Dyvorne H, O'Halloran R, Poole M, Yuen M, Mazurek M, Ward A, Payabvash S, Beekman R, Brown S, Falcone G, Gobeske K, Petersen N, Jasne A, Sharma R, Schindler J, Sansing L, Gilmore E, Wira C, Matouk C, Sze G, Rosen M, Kimberly W, Sheth K. Abstract 57: Deployment of Portable, Bedside, Low-Field Magnetic Resonance Imaging for Evaluation of Stroke Patients. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.57.
- Abstract 117: Fixed Compared to Autoregulation-oriented Blood Pressure Thresholds After Mechanical Thrombectomy for Ischemic StrokePetersen N, Silverman A, Strander S, Kodali S, Wang A, Sansing L, Schindler J, Falcone G, Gilmore E, Jasne A, Cord B, Hebert R, Johnson M, Matouk C, Sheth K. Abstract 117: Fixed Compared to Autoregulation-oriented Blood Pressure Thresholds After Mechanical Thrombectomy for Ischemic Stroke. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.117.
- Abstract WP374: High Frequency Blood Pressure Monitoring in the Acute Phase of Large Vessel Occlusion Ischemic StrokePeshwe K, Nguyen C, Kimmel A, Kodali S, Silverman A, Strander S, Wang A, Wira C, Sansing L, Matouk C, Sheth K, Petersen N. Abstract WP374: High Frequency Blood Pressure Monitoring in the Acute Phase of Large Vessel Occlusion Ischemic Stroke. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wp374.
- Abstract TP40: Time From Stroke Onset to Reperfusion is Associated With Worse Functional Outcomes in Patients With Rapidly Progressing InfarctsWang A, Strander S, Kodali S, Silverman A, Kimmel A, Nguyen C, Peshwe K, Sansing L, Schindler J, Matouk C, Sheth K, Petersen N. Abstract TP40: Time From Stroke Onset to Reperfusion is Associated With Worse Functional Outcomes in Patients With Rapidly Progressing Infarcts. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tp40.
- Abstract TP417: An Autoregulation-Derived Prediction Model for Midline Shift After Ischemic StrokeSilverman A, Wang A, Kodali S, Strander S, Kimmel A, Nguyen C, Peshwe K, Matouk C, Kimberly W, Sheth K, Tan C, Petersen N. Abstract TP417: An Autoregulation-Derived Prediction Model for Midline Shift After Ischemic Stroke. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tp417.
- Abstract TP11: CTA Collateral Status and Final Infarct Distribution Following Thrombectomy in Stroke Patients With Large Vessel OcclusionAl-Dasuqi K, Payabvash S, Abou Karam A, Strander S, Kodali S, Silverman A, Sansing L, Schindler J, Matouk C, Sheth K, Malhotra A, Petersen N. Abstract TP11: CTA Collateral Status and Final Infarct Distribution Following Thrombectomy in Stroke Patients With Large Vessel Occlusion. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tp11.
- Abstract TMP89: Impaired Cerebral Autoregulation Increases Risk of Worse Outcome After Endovascular Thrombectomy in Stroke Patients With High Blood Pressure VariabilityNguyen C, Silverman A, Wang A, Kodali S, Strander S, Kimmel A, Peshwe K, De Havenon A, Gilmore E, Matouk C, Sansing L, Schindler J, Sheth K, Petersen N. Abstract TMP89: Impaired Cerebral Autoregulation Increases Risk of Worse Outcome After Endovascular Thrombectomy in Stroke Patients With High Blood Pressure Variability. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tmp89.
- Preliminary Experience With Proximal Flow Reversal During Intracranial Balloon Angioplasty and Stenting for Symptomatic, Severe Intracranial StenosisCord B, Santarosa C, Sujijantarat N, Kundishora A, Falcone G, Sheth K, Sansing L, Schindler J, Petersen N, Matouk C. Preliminary Experience With Proximal Flow Reversal During Intracranial Balloon Angioplasty and Stenting for Symptomatic, Severe Intracranial Stenosis. Neurosurgery 2019, 66: 310-675. DOI: 10.1093/neuros/nyz310_675.
- Deviation from Dynamic and Personalized Optimal Blood Pressure Targets is Associated With Worse Functional Outcomes After Aneurysmal Subarachnoid HemorrhageSilverman A, Kodali S, Strander S, Gilmore E, Kimmel A, Wang A, Cord B, Falcone G, Hebert R, Matouk C, Sheth K, Petersen N. Deviation from Dynamic and Personalized Optimal Blood Pressure Targets is Associated With Worse Functional Outcomes After Aneurysmal Subarachnoid Hemorrhage. Neurosurgery 2019, 66: 310-186. DOI: 10.1093/neuros/nyz310_186.
- Percutaneous Trans-Carotid Puncture for Mechanical Thrombectomy in Acute Ischemic Stroke Patients is Safe and Effective: A Large, Single-Center Case SeriesCord B, Wang A, Chouairi F, Koo A, Porto C, Silverman A, Kodali S, Strander S, Falcone G, Sheth K, Hebert R, Sansing L, Schindler J, Petersen N, Matouk C. Percutaneous Trans-Carotid Puncture for Mechanical Thrombectomy in Acute Ischemic Stroke Patients is Safe and Effective: A Large, Single-Center Case Series. Neurosurgery 2019, 66: 310-167. DOI: 10.1093/neuros/nyz310_167.
- Implications of Achieving TICI 2b Versus TICI 3 Reperfusion in Patients With Ischemic Stroke: A Cost-Effectiveness AnalysisWu X, Gandhi D, Matouk C, Schindler J, Hughes D, Forman H, Sanelli P, Malhotra A. Implications of Achieving TICI 2b Versus TICI 3 Reperfusion in Patients With Ischemic Stroke: A Cost-Effectiveness Analysis. Neurosurgery 2019, 66: 310-670. DOI: 10.1093/neuros/nyz310_670.
- Poor Collaterals and Malignant CT Perfusion Profiles Are Associated with Increased Vulnerability to Blood Pressure Reductions during Endovascular Therapy (S57.002)Strander S, Payabvash S, Wang A, Kodali S, Silverman A, Agarwal T, Stretz C, Zheng-Lin B, Cardenas G, Sansing L, Schindler J, Matouk C, Hebert R, Sheth K, Gutierrez S, Petersen N. Poor Collaterals and Malignant CT Perfusion Profiles Are Associated with Increased Vulnerability to Blood Pressure Reductions during Endovascular Therapy (S57.002). Neurology 2019, 92 DOI: 10.1212/wnl.92.15_supplement.s57.002.
- Dynamic Cerebral Autoregulation and Personalized Blood Pressure Monitoring in Patients with Aneurysmal Subarachnoid Hemorrhage (aSAH) (P5.3-025)Silverman A, Wang A, Kodali S, Strander S, Cord B, Hebert R, Matouk C, Sheth K, Gilmore E, Petersen N. Dynamic Cerebral Autoregulation and Personalized Blood Pressure Monitoring in Patients with Aneurysmal Subarachnoid Hemorrhage (aSAH) (P5.3-025). Neurology 2019, 92 DOI: 10.1212/wnl.92.15_supplement.p5.3-025.
- Ischemic and Hemorrhagic Stroke in Native Americans (P3.9-011)King Z, Beekman R, Brown S, Leasure A, Orgas H, Gilmore E, Sansing L, Matouk C, Sheth K, Falcone G. Ischemic and Hemorrhagic Stroke in Native Americans (P3.9-011). Neurology 2019, 92 DOI: 10.1212/wnl.92.15_supplement.p3.9-011.
- Genetic Risk Loci for Cholesterol Levels are Associated with Risk of Spontaneous Intracerebral Hemorrhage (S2.002)Kirsch E, Leasure A, Noche R, Matouk C, Sansing L, Crawford K, Kourkoulis C, Woo D, Rosand J, Anderson C, Sheth K, Falcone G. Genetic Risk Loci for Cholesterol Levels are Associated with Risk of Spontaneous Intracerebral Hemorrhage (S2.002). Neurology 2019, 92 DOI: 10.1212/wnl.92.15_supplement.s2.002.
- Racial/Ethnic Disparities in the Risk of Intracerebral Hemorrhage Recurrence (S15.005)Leasure A, King Z, Torres-Lopez V, Murthy S, Kamel H, Shoamanesh A, Salman R, Rosand J, Ziai W, Hanley D, Woo D, Matouk C, Sansing L, Falcone G, Sheth K. Racial/Ethnic Disparities in the Risk of Intracerebral Hemorrhage Recurrence (S15.005). Neurology 2019, 92 DOI: 10.1212/wnl.92.15_supplement.s15.005.
- Validation of the original FRESH score in patients with subarachnoid hemorrhage (P5.9-039)Witsch J, Kuohn L, Matouk C, Hebert R, Cord B, Sansing L, Falcone G, Sheth K. Validation of the original FRESH score in patients with subarachnoid hemorrhage (P5.9-039). Neurology 2019, 92 DOI: 10.1212/wnl.92.15_supplement.p5.9-039.
- Abstract WP223: Ischemic and Hemorrhagic Stroke in Native AmericansKing Z, Beekman R, Chu S, Leasure A, Orgrass H, Gilmore E, Sansing L, Matouk C, Sheth K, Falcone G. Abstract WP223: Ischemic and Hemorrhagic Stroke in Native Americans. Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.wp223.
- Abstract WMP97: Racial/Ethnic Disparities in the Risk of Intracerebral Hemorrhage RecurrenceKing Z, Leasure A, Torres-Lopez V, Woo D, Hanley D, Ziai W, Murthy S, Matouk C, Sansing L, Falcone G, Sheth K. Abstract WMP97: Racial/Ethnic Disparities in the Risk of Intracerebral Hemorrhage Recurrence. Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.wmp97.
- Abstract TP15: Percutaneous Transcarotid Puncture is a Viable Alternative for Thrombectomy in Acute Ischemic Stroke Patients With Difficult Vascular AccessWang A, Cord B, Chouairi F, Koo A, Porto C, Silverman A, Kodali S, Strander S, Hebert R, Falcone G, Sheth K, Sansing L, Schindler J, Matouk C, Petersen N. Abstract TP15: Percutaneous Transcarotid Puncture is a Viable Alternative for Thrombectomy in Acute Ischemic Stroke Patients With Difficult Vascular Access. Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.tp15.
- Abstract 77: Perihematomal Edema Expansion Rate is Associated With Poor Functional Outcomes in Basal Ganglia Intracerebral HemorrhageLeasure A, Qureshi A, Goldstein J, Murthy S, Kamel H, Woo D, Matouk C, Sansing L, Falcone G, Sheth K. Abstract 77: Perihematomal Edema Expansion Rate is Associated With Poor Functional Outcomes in Basal Ganglia Intracerebral Hemorrhage. Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.77.
- Abstract 76: Intensive Blood Pressure Reduction is Associated With Reduced Hematoma Expansion in Deep Intracerebral Hemorrhage: A Secondary Analysis of ATACH-2Leasure A, Qureshi A, Goldstein J, Murthy S, Kamel H, Woo D, Matouk C, Sansing L, Sheth K, Falcone G. Abstract 76: Intensive Blood Pressure Reduction is Associated With Reduced Hematoma Expansion in Deep Intracerebral Hemorrhage: A Secondary Analysis of ATACH-2. Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.76.
- Abstract 18: Genetically-Determined Cholesterol Levels are Associated with Risk of Spontaneous Intracerebral HemorrhageKirsch E, Leasure A, Matouk C, Sansing L, Crawford K, Kourkoulis C, Woo D, Rosand J, Anderson C, Sheth K, Falcone G. Abstract 18: Genetically-Determined Cholesterol Levels are Associated with Risk of Spontaneous Intracerebral Hemorrhage. Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.18.
- Abstract WP3: Decreases in Blood Pressure During Endovascular Stroke Therapy are Associated With Larger Infarct Volumes and Poor Functional OutcomePetersen N, Wang A, Zhen-Li B, Strander S, Kodali S, Silverman A, Sansing L, Lopez G, Schindler J, Matouk C, Hebert R, Sheth K, Ortega Gutierrez S. Abstract WP3: Decreases in Blood Pressure During Endovascular Stroke Therapy are Associated With Larger Infarct Volumes and Poor Functional Outcome. Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.wp3.
- Abstract TP34: Malignant CT Perfusion Profile is Associated With Increased Sensitivity to Blood Pressure Reductions During Endovascular Stroke TherapyStrander S, Wang A, Kodali S, Silverman A, Agarwal T, Stretz C, Zheng-Lin B, Lopez Cardenas G, Sansing L, Schindler J, Matouk C, Hebert R, Sheth K, Ortega Gutierrez S, Petersen N. Abstract TP34: Malignant CT Perfusion Profile is Associated With Increased Sensitivity to Blood Pressure Reductions During Endovascular Stroke Therapy. Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.tp34.
- Abstract 95: Exceeding Personalized Blood Pressure Targets After Endovascular Stroke Therapy is Associated With Hemorrhagic Transformation and Worse Functional OutcomePetersen N, Wang A, Strander S, Kodali S, Silverman A, Gilmore E, Sansing L, Schindler J, Hebert R, Cord B, Matouk C, Sheth K. Abstract 95: Exceeding Personalized Blood Pressure Targets After Endovascular Stroke Therapy is Associated With Hemorrhagic Transformation and Worse Functional Outcome. Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.95.
- Abstract 147: Individualized Blood Pressure Management After Subarachnoid Hemorrhage Using Real-time Autoregulation Monitoring: A Pilot Study Using NIRS and ICP-derived Limits of AutoregulationSilverman A, Wang A, Kodali S, Strander S, Cord B, Hebert R, Matouk C, Gilmore E, Sheth K, Petersen N. Abstract 147: Individualized Blood Pressure Management After Subarachnoid Hemorrhage Using Real-time Autoregulation Monitoring: A Pilot Study Using NIRS and ICP-derived Limits of Autoregulation. Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.147.
- 57 Improving the Safety and Quality of Inter-Hospital Transfer for Nontraumatic Intracerebral and Subarachnoid HemorrhageLittauer R, Sather J, Rothenberg C, Finn E, Yip M, Matouk C, Pham L, Sheth K, Ulrich A, Parwani Y, Venkatesh A. 57 Improving the Safety and Quality of Inter-Hospital Transfer for Nontraumatic Intracerebral and Subarachnoid Hemorrhage. Annals Of Emergency Medicine 2018, 72: s25-s26. DOI: 10.1016/j.annemergmed.2018.08.062.
- Intracranial vessel wall MRI: Principles and expert consensus Recommendations of the American Society of NeuroradiologyMandell D, Mossa-Basha M, Qiao Y, Hess C, Hui F, Matouk C, Johnson M, Daemen M, Vossough A, Edjlali M, Saloner D, Ansari S, Wasserman B, Mikulis D. Intracranial vessel wall MRI: Principles and expert consensus Recommendations of the American Society of Neuroradiology. International Journal Of Cerebrovascular Diseases 2018, 26: 641-653. DOI: 10.3760/cma.j.issn.1673-4165.2018.09.001.
- 316 Screening for Intracranial Aneurysms in Patients With Autosomal Dominant Polycystic Kidney DiseaseWu X, Matouk C, Malhotra A. 316 Screening for Intracranial Aneurysms in Patients With Autosomal Dominant Polycystic Kidney Disease. Neurosurgery 2018, 65: 128. DOI: 10.1093/neuros/nyy303.316.
- 315 Comparative Effectiveness Analysis of Pipeline Embolization Device versus Coiling in Unruptured Aneurysms Less Than 10 mm in SizeWu X, Cord B, Sommaruga S, Matouk C, Malhotra A. 315 Comparative Effectiveness Analysis of Pipeline Embolization Device versus Coiling in Unruptured Aneurysms Less Than 10 mm in Size. Neurosurgery 2018, 65: 127-128. DOI: 10.1093/neuros/nyy303.315.
- 148 Management of Unruptured Intracranial Aneurysms in the ElderlyWu X, Cord B, Sommaruga S, Matouk C, Malhotra A. 148 Management of Unruptured Intracranial Aneurysms in the Elderly. Neurosurgery 2018, 65: 97. DOI: 10.1093/neuros/nyy303.148.
- 105 Decreases in Blood Pressure During Endovascular Stroke Therapy Are Common and Associated With Poor Functional OutcomeMampre D, Wang A, Sheth K, Tan C, Hebert R, Matouk C, Petersen N. 105 Decreases in Blood Pressure During Endovascular Stroke Therapy Are Common and Associated With Poor Functional Outcome. Neurosurgery 2018, 65: 82. DOI: 10.1093/neuros/nyy303.105.
- Risk of Branch Occlusion and Ischemic Complications with the Pipeline Embolization Device in the Treatment of Posterior Circulation AneurysmsAdeeb N, Griessenauer C, Dmytriw A, Shallwani H, Gupta R, Foreman P, Shakir H, Moore J, Limbucci N, Mangiafico S, Kumar A, Michelozzi C, Zhang Y, Pereira V, Matouk C, Harrigan M, Siddiqui A, Levy E, Renieri L, Marotta T, Cognard C, Ogilvy C, Thomas A. Risk of Branch Occlusion and Ischemic Complications with the Pipeline Embolization Device in the Treatment of Posterior Circulation Aneurysms. American Journal Of Neuroradiology 2018, 39: 1303-1309. PMID: 29880475, PMCID: PMC7655425, DOI: 10.3174/ajnr.a5696.
- Predictors of Vessel Wall Enhancement in Unruptured Intracranial AneurysmsSommaruga S, Cord B, Santarosa C, Malhotra A, Jonhson M, Sheth K, Gunel M, Herbert R, Bijlenga P, Schaller K, Falcone G, Matouk C. Predictors of Vessel Wall Enhancement in Unruptured Intracranial Aneurysms. Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660769.
- Spontaneous Intracerebral Hemorrhage in the Elderly PopulationSommaruga S, Beekman R, Chu S, King Z, Matouk C, Hwang D, Sheth K, Falcone G. Spontaneous Intracerebral Hemorrhage in the Elderly Population. Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660768.
- History of Intracranial Hemorrhage Is Associated with In-Hospital Mortality in Ischemic Stroke Patients Treated with Intravenous ThrombolyticsSommaruga S, Chu S, Hwang D, Dearborn J, Sansing L, Cord B, Santarosa C, Samarth G, Petersen N, Gilmore E, Schindler J, Bijlenga P, Schaller K, Matouk C, Sheth K, Falcone G. History of Intracranial Hemorrhage Is Associated with In-Hospital Mortality in Ischemic Stroke Patients Treated with Intravenous Thrombolytics. Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660745.
- High-Resolution MRI with Black Blood Sequence Increases Physician Confidence in Identification of Rupture Site in Cerebral AVMs: Application to Treatment StrategiesSommaruga S, Cord B, Minja F, Malhotra A, Johnson M, Bijlenga P, Schaller K, Matouk C. High-Resolution MRI with Black Blood Sequence Increases Physician Confidence in Identification of Rupture Site in Cerebral AVMs: Application to Treatment Strategies. Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660760.
- High-Resolution Vessel Wall MRI in Ruptured Cranial Dural Arteriovenous FistulasSommaruga S, Cord B, Santarosa C, Yeung J, Johnson M, Hebert R, Bijlenga P, Schaller K, Matouk C. High-Resolution Vessel Wall MRI in Ruptured Cranial Dural Arteriovenous Fistulas. Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660759.
- Autoregulation-based Blood Pressure Optimization After Large-vessel Ischemic Stroke using Non-invasive Near-infrared Spectroscopy Monitoring (S21.008)Wang A, Sheth K, Marshall R, Mampre D, Hebert R, Matouk C, Petersen N. Autoregulation-based Blood Pressure Optimization After Large-vessel Ischemic Stroke using Non-invasive Near-infrared Spectroscopy Monitoring (S21.008). Neurology 2018, 90 DOI: 10.1212/wnl.90.15_supplement.s21.008.
- Decreases in Blood Pressure During Endovascular Stroke Therapy are Common and Associated with Poor Functional Outcome (S21.004)Wang A, Mampre D, Sheth K, Tan C, Hebert R, Matouk C, Petersen N. Decreases in Blood Pressure During Endovascular Stroke Therapy are Common and Associated with Poor Functional Outcome (S21.004). Neurology 2018, 90 DOI: 10.1212/wnl.90.15_supplement.s21.004.
- Spontaneous Intracerebral Hemorrhage in the Elderly Population (S10.006)Beekman R, Chu S, Sommaruga S, King Z, Kamel H, Matouk C, Hwang D, Sheth K, Falcone G. Spontaneous Intracerebral Hemorrhage in the Elderly Population (S10.006). Neurology 2018, 90 DOI: 10.1212/wnl.90.15_supplement.s10.006.
- Safety Outcomes of Thrombolysis for Acute Ischemic Stroke in Patients with History of Intracranial Hemorrhage (P4.033)Chu S, Sommaruga S, Hwang D, Dearborn J, Sansing L, Cord B, Samarth G, Petersen N, Gilmore E, Schindler J, Matouk C, Sheth K, Falcone G. Safety Outcomes of Thrombolysis for Acute Ischemic Stroke in Patients with History of Intracranial Hemorrhage (P4.033). Neurology 2018, 90 DOI: 10.1212/wnl.90.15_supplement.p4.033.
- Abstract WMP31: Vessel Wall Enhancement is Associated With Clinical and Imaging Markers of Aneurysm InstabilitySommaruga S, Cord B, Molhotra A, Johnson M, Minja F, Gunel M, Sheth K, Herbert R, Melnikov F, Schaller K, Mandell D, Bijlenga P, Falcone G, Matouk C. Abstract WMP31: Vessel Wall Enhancement is Associated With Clinical and Imaging Markers of Aneurysm Instability. Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.wmp31.
- Abstract TMP14: Thrombolysis in Ischemic Stroke Patients with Prior History of Intracranial HemorrhageChu S, Sommaruga S, Hwang D, Dearborn J, Sansing L, Matouk C, Samarth G, Petersen N, Gilmore E, Schindler J, Sheth K, Falcone G. Abstract TMP14: Thrombolysis in Ischemic Stroke Patients with Prior History of Intracranial Hemorrhage. Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.tmp14.
- Abstract TP38: Drip and Ship versus Direct Transfer to Comprehensive Stroke Center: A Modelling Based AnalysisMalhotra A, Wu X, Matouk C, Schindler J. Abstract TP38: Drip and Ship versus Direct Transfer to Comprehensive Stroke Center: A Modelling Based Analysis. Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.tp38.
- Abstract WP320: Blood Pressure Reduction During Endovascular Stroke Therapy is Associated With Poor Functional OutcomeWang A, Mampre D, Sheth K, Tan C, Matouk C, Hebert R, Petersen N. Abstract WP320: Blood Pressure Reduction During Endovascular Stroke Therapy is Associated With Poor Functional Outcome. Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.wp320.
- Carotid Artery Wall Imaging: Perspective and Guidelines from the ASNR Vessel Wall Imaging Study Group and Expert Consensus Recommendations of the American Society of NeuroradiologySaba L, Yuan C, Hatsukami T, Balu N, Qiao Y, DeMarco J, Saam T, Moody A, Li D, Matouk C, Johnson M, Jäger H, Mossa-Basha M, Kooi M, Fan Z, Saloner D, Wintermark M, Mikulis D, Wasserman B. Carotid Artery Wall Imaging: Perspective and Guidelines from the ASNR Vessel Wall Imaging Study Group and Expert Consensus Recommendations of the American Society of Neuroradiology. American Journal Of Neuroradiology 2018, 39: e9-e31. PMID: 29326139, PMCID: PMC7410574, DOI: 10.3174/ajnr.a5488.
- 295 Interhospital Transfer is Not a Predictor of In-Hospital Mortality for Patients With Nontraumatic Intracranial HemorrhageYip M, Sather J, Sheth K, Matouk C, Littauer R, Finn E, Rothenberg C, Costello D, Parwani V, Venkatesh A. 295 Interhospital Transfer is Not a Predictor of In-Hospital Mortality for Patients With Nontraumatic Intracranial Hemorrhage. Annals Of Emergency Medicine 2017, 70: s116-s117. DOI: 10.1016/j.annemergmed.2017.07.273.
- 168 Wall Enhancement in Unruptured Aneurysms is Associated with Symptomatic Presentation and SizeCord B, Sommaruga S, Hebert R, Malhotra A, Johnson M, Minja F, Gunel M, Sheth K, Falcone G, Matouk C. 168 Wall Enhancement in Unruptured Aneurysms is Associated with Symptomatic Presentation and Size. Neurosurgery 2017, 64: 243. DOI: 10.1093/neuros/nyx417.168.
- Aneurysmal Subarachnoid HemorrhageWhite J, Matouk C. Aneurysmal Subarachnoid Hemorrhage. 2017, 55-74. DOI: 10.1007/978-3-319-48669-7_4.
- O-021 Pipeline embolization of posterior circulation aneurysms: a multicenter study of 131 aneurysmsGriessenauer C, Ogilvy C, Adeeb N, Dmytriw A, Foreman P, Shallwani H, Limbucci N, Mangiafico S, Kumar A, Michelozzi C, Krings T, Pereira V, Matouk C, Harrigan M, Shakir H, Siddiqui A, Levy E, Renieri L, Marotta T, Cognard C, Thomas A. O-021 Pipeline embolization of posterior circulation aneurysms: a multicenter study of 131 aneurysms. Journal Of NeuroInterventional Surgery 2017, 9: a13. DOI: 10.1136/neurintsurg-2017-snis.21.
- O-018 Flow diversion for the treatment of basilar apex aneurysmsDmytriw, Adeeb N, Kumar A, Griessenauer C, Ogilvy C, Foreman P, Shallwani H, Limbucci N, Mangiafico S, Michelozzi C, Krings T, Pereira V, Matouk C, Zhang Y, Harrigan M, Phan K, Shakir H, Siqqiqui A, Levy E, Renieri L, Cognard C, Thomas A, Marotta T. O-018 Flow diversion for the treatment of basilar apex aneurysms. Journal Of NeuroInterventional Surgery 2017, 9: a11. DOI: 10.1136/neurintsurg-2017-snis.18.
- E-050 First-Line Treatment by Embolization with Intention-to-Cure in the Management of Cranial Dural Arteriovenous FistulasCord B, Sommaruga S, Yeung J, Johnson M, Matouk C. E-050 First-Line Treatment by Embolization with Intention-to-Cure in the Management of Cranial Dural Arteriovenous Fistulas. Journal Of NeuroInterventional Surgery 2016, 8: a70. DOI: 10.1136/neurintsurg-2016-012589.122.
- Regarding “Clinical and Imaging Follow-Up of Patients with Coiled Basilar Tip Aneurysms Up to 20 Years”Malhotra A, Wu X, Kalra V, Matouk C, Forman H. Regarding “Clinical and Imaging Follow-Up of Patients with Coiled Basilar Tip Aneurysms Up to 20 Years”. American Journal Of Neuroradiology 2016, 37: e39-e39. PMID: 26822726, PMCID: PMC7960187, DOI: 10.3174/ajnr.a4708.
- High-Resolution Vessel Wall Magnetic Resonance Imaging in Angiogram-Negative Non-Perimesencephalic Subarachnoid HemorrhageCoutinho J, Sacho R, Schaafsma J, Agid R, Krings T, Radovanovic I, Matouk C, Mikulis D, Mandell D. High-Resolution Vessel Wall Magnetic Resonance Imaging in Angiogram-Negative Non-Perimesencephalic Subarachnoid Hemorrhage. Clinical Neuroradiology 2015, 27: 175-183. PMID: 26608742, DOI: 10.1007/s00062-015-0484-x.
- Practical Microsurgical and Endovascular Treatment of VasospasmBulsara K, Grant R, Matouk C. Practical Microsurgical and Endovascular Treatment of Vasospasm. 2015, 75-75. DOI: 10.5005/jp/books/12423_12.
- Vessel Wall Magnetic Resonance Imaging Identifies the Site of Rupture in Patients With Multiple Intracranial AneurysmsProof of PrincipleMatouk CC, Mandell DM, Günel M, Bulsara KR, Malhotra A, Hebert R, Johnson MH, Mikulis DJ, Minja FJ. Vessel Wall Magnetic Resonance Imaging Identifies the Site of Rupture in Patients With Multiple Intracranial AneurysmsProof of Principle. Neurosurgery 2013, 72: 492-496. PMID: 23151622, DOI: 10.1227/neu.0b013e31827d1012.
- Epigenetics and stroke risk – beyond the static DNA codeMarsden P, Matouk C, Turgeon P. Epigenetics and stroke risk – beyond the static DNA code. Advances In Genomics And Genetics 2012, Volume 2: 67-84. DOI: 10.2147/agg.s18697.
- Long-Term Clinical and Imaging Follow-Up of Complex Intracranial Aneurysms Treated by Endovascular Parent Vessel OcclusionMatouk CC, Kaderali Z, terBrugge KG, Willinsky RA. Long-Term Clinical and Imaging Follow-Up of Complex Intracranial Aneurysms Treated by Endovascular Parent Vessel Occlusion. American Journal Of Neuroradiology 2012, 33: 1991-1997. PMID: 22555575, PMCID: PMC7964607, DOI: 10.3174/ajnr.a3079.
- Carotid Artery Angioplasty and Stenting for Patients Less than 70 Years-of-AgeAlkins R, Matouk CC, Cruz JP, Marotta T, Montanera W, Spears J. Carotid Artery Angioplasty and Stenting for Patients Less than 70 Years-of-Age. Canadian Journal Of Neurological Sciences / Journal Canadien Des Sciences Neurologiques 2012, 39: 338-342. PMID: 22547514, DOI: 10.1017/s0317167100013470.
- The Pipeline Flow-Diverting Stent for Exclusion of Ruptured Intracranial Aneurysms With Difficult MorphologiesMartin AR, Cruz JP, Matouk CC, Spears J, Marotta TR. The Pipeline Flow-Diverting Stent for Exclusion of Ruptured Intracranial Aneurysms With Difficult Morphologies. Neurosurgery 2012, 70: ons21-ons28. PMID: 21841519, DOI: 10.1227/neu.0b013e3182315ee3.
- Vessel Wall MRI to Differentiate Between Reversible Cerebral Vasoconstriction Syndrome and Central Nervous System VasculitisMandell DM, Matouk CC, Farb RI, Krings T, Agid R, terBrugge K, Willinsky RA, Swartz RH, Silver FL, Mikulis DJ. Vessel Wall MRI to Differentiate Between Reversible Cerebral Vasoconstriction Syndrome and Central Nervous System Vasculitis. Stroke 2011, 43: 860-862. PMID: 22156692, DOI: 10.1161/strokeaha.111.626184.
- Osteogenesis Imperfecta, Multiple Intra-Abdominal Arterial Dissections and a Ruptured Dissecting-Type Intracranial AneurysmMatouk C, Hanbidge A, Mandell D, Terbrugge K, Agid R. Osteogenesis Imperfecta, Multiple Intra-Abdominal Arterial Dissections and a Ruptured Dissecting-Type Intracranial Aneurysm. Interventional Neuroradiology 2011, 17: 371-375. PMID: 22005702, PMCID: PMC3396044, DOI: 10.1177/159101991101700315.
- Hydrocephalus Secondary to Hydrodynamic Disequilibrium in an Adult Patient with a Choroidal-Type Arteriovenous MalformationEbinu J, Matouk C, Wallace M, Terbrugge K, Krings T. Hydrocephalus Secondary to Hydrodynamic Disequilibrium in an Adult Patient with a Choroidal-Type Arteriovenous Malformation. Interventional Neuroradiology 2011, 17: 212-216. PMID: 21696661, PMCID: PMC3287273, DOI: 10.1177/159101991101700212.
- Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones.Fish J, Yan M, Matouk C, St. Bernard R, Ho J, Gavryushova A, Srivastava D, Marsden P. Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones. Journal Of Biological Chemistry 2010, 285: 11754. PMCID: PMC2857053, DOI: 10.1074/jbc.a109.067868.
- Epigenetic Regulation of Vascular Endothelial Gene ExpressionMatouk CC, Marsden PA. Epigenetic Regulation of Vascular Endothelial Gene Expression. Circulation Research 2008, 102: 873-887. PMID: 18436802, DOI: 10.1161/circresaha.107.171025.
- Activation of ETB receptors regulates the abundance of ET‐1 mRNA in vascular endothelial cellsFarhat N, Matouk C, Mamarbachi A, Marsden P, Allen B, Thorin E. Activation of ETB receptors regulates the abundance of ET‐1 mRNA in vascular endothelial cells. British Journal Of Pharmacology 2008, 153: 1420-1431. PMID: 18278064, PMCID: PMC2437912, DOI: 10.1038/bjp.2008.25.
- Chapter 26 Molecular Insights into the Thrombotic MicroangiopathiesMatouk C, Marsden P. Chapter 26 Molecular Insights into the Thrombotic Microangiopathies. 2008, 453-cp4. DOI: 10.1016/b978-1-4160-0252-9.50030-6.
- Chapter 78 Midbrain GliomasMatouk C, McDonald P, Drake J. Chapter 78 Midbrain Gliomas. 2005, 599-603. DOI: 10.1016/b978-0-7216-8148-1.50081-4.
Clinical Trials
Conditions | Study Title |
---|---|
Diseases of the Cardiovascular System | INSPIRE Pipeline™ Shield Post Approval Study |
Diseases of the Cardiovascular System | THUNDER: Acute Ischemic Stroke Study With the Penumbra System® Including Thunderbolt™ Aspiration Tubing |
Diseases of the Cardiovascular System | EvaLuate EndoVascular Treatment of Acutely Ruptured Shallow Intradural Aneurysms With the Pipeline™ Flex Embolization Device With Shield TEchnology™ (ELEVATE) |
Diseases of the Nervous System | US Pilot Study of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus |