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Emily J. Gilmore

MD, FNCS, FACNS
Associate Professor; Director, Neurosciences Intensive Care Unit, Neurology; Co-director, Neuorotrauma, Neurology & Neurosurgery

Contact Information

Emily J. Gilmore, MD, FNCS, FACNS
Yale Medicine

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Research Summary

Our group and collaborations to date have focused on the use of continuous EEG (cEEG) monitoring in patients with severe brain injury, either secondary to a primary brain process or as a manifestions of systemic disease. We have several ongoing projects in the following areas: 1) the role of cEEG and cerebral oximetry (NIRS) monitoring in understanding cerebral perfusion and autoregulation in severe sepsis; 2) the impact of potentially harmful EEG patterns on management and outcome in critical illness; 3) novel approaches to invasive multimodality brain monitoring; and 4) the prognostic role of various EEG signatures in post-anoxic brain injury. In addition to being the site-PI for several trials, I have also authored chapters on neuromonitoring and have experience with multimodalty monitoring, which involves using information from probes placed in the acutely injured brain of comatose patients to guide medical management.


Coauthors

Research Interests

Brain Injuries; Cerebral Hemorrhage; Cerebrovascular Disorders; Critical Care; Delirium; Education; Electroencephalography; Neurosciences; Status Epilepticus; Subarachnoid Hemorrhage; Treatment Outcome; Stroke

Selected Publications

  • Emergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfaAmmar A, Elsamadicy A, Ammar M, Reeves B, Koo A, Falcone G, Hwang D, Petersen N, Kim J, Beekman R, Prust M, Magid-Bernstein J, Acosta J, Herbert R, Sheth K, Matouk C, Gilmore E. Emergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfa Clinical Neurology And Neurosurgery 2023, 226: 107621. PMID: 36791588, DOI: 10.1016/j.clineuro.2023.107621.
  • Abstract 9: Autoregulation-based Blood Pressure Targets After Endovascular ThrombectomyPetersen N, Begunova Y, Olexa M, Bartolome D, Kumar A, Chen Y, Dhar R, Peng T, Ortega-Gutierrez S, Falcone G, gilmore E, Kim J, Schindler J, Sansing L, Matouk C, Sheth K. Abstract 9: Autoregulation-based Blood Pressure Targets After Endovascular Thrombectomy Stroke 2023, 54: a9-a9. DOI: 10.1161/str.54.suppl_1.9.
  • Future of Neurology & Technology: Neuroimaging Made Accessible Using Low-Field, Portable MRIParasuram N, Crawford A, Mazurek M, Chavva I, Beekman R, Gilmore E, Petersen N, Payabvash S, Sze G, Iglesias J, Omay S, Matouk C, Longbrake E, de Havenon A, Schiff S, Rosen M, Kimberly W, Sheth K. Future of Neurology & Technology: Neuroimaging Made Accessible Using Low-Field, Portable MRI Neurology 2023, 10.1212/wnl.0000000000207074. PMID: 36720639, DOI: 10.1212/wnl.0000000000207074.
  • Abstract 159: Time-course Of Left Ventricular Systolic Dysfunction Recovery After Cardiac ArrestBeekman R, Kim N, Faridi K, Aneni E, Chang T, Arakaki A, Kitlen E, Miller E, Khosla A, Wira C, Greer D, gilmore E. Abstract 159: Time-course Of Left Ventricular Systolic Dysfunction Recovery After Cardiac Arrest Circulation 2022, 146: a159-a159. DOI: 10.1161/circ.146.suppl_1.159.
  • Abstract 156: Clinical Significance Of Left Ventricular Systolic Dysfunction After Cardiac ArrestBeekman R, Kim N, Faridi K, Aneni E, Chang T, Arakaki A, Kitlen E, Miller E, Khosla A, Wira C, Greer D, gilmore E. Abstract 156: Clinical Significance Of Left Ventricular Systolic Dysfunction After Cardiac Arrest Circulation 2022, 146: a156-a156. DOI: 10.1161/circ.146.suppl_1.156.
  • Abstract 176: Development Of A Novel Score To Predict Brain Death After Out Of Hospital Cardiac ArrestKitlen E, Kim N, Rubenstein A, Keenan C, Greer D, gilmore E, Beekman R. Abstract 176: Development Of A Novel Score To Predict Brain Death After Out Of Hospital Cardiac Arrest Circulation 2022, 146: a176-a176. DOI: 10.1161/circ.146.suppl_1.176.
  • Abstract 89: Nimodipine-induced Blood Pressure Reductions Below Personalized Limits Of Autoregulation Are Associated With Worse Outcomes After Subarachnoid HemorrhageBartolome D, Begunova Y, Prasad A, Soto A, Kobsa J, Top I, Quispe-Orozco D, Farooqui M, Zevallos C, Kim J, Gilmore E, Beekman R, de Havenon A, Matouk C, Sheth K, Ortega-Gutierrez S, Petersen N. Abstract 89: Nimodipine-induced Blood Pressure Reductions Below Personalized Limits Of Autoregulation Are Associated With Worse Outcomes After Subarachnoid Hemorrhage Stroke 2022, 53: a89-a89. DOI: 10.1161/str.53.suppl_1.89.
  • The Significance of LRDA With Bilateral Involvement Compared With GRDA on EEG in Critically Ill PatientsFong M, Jadav R, Alzawahmah M, Hussein O, Gilmore E, Hirsch L. The Significance of LRDA With Bilateral Involvement Compared With GRDA on EEG in Critically Ill Patients Journal Of Clinical Neurophysiology 2021, Publish Ahead of Print DOI: 10.1097/wnp.0000000000000897.
  • Abstract P41: Integrating Demographics, TCD and EEG Diagnostic Modalities Improves Delayed Cerebral Ischemia Prediction After Subarachnoid HemorrhageChen H, Elmer J, Ghanta M, Valdery-Moura J, Zahar S, Rosenthal E, Gilmore E, Hirsch L, Zaveri H, Sheth K, Petersen N, Westover M, Kim J. Abstract P41: Integrating Demographics, TCD and EEG Diagnostic Modalities Improves Delayed Cerebral Ischemia Prediction After Subarachnoid Hemorrhage Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p41.
  • Abstract P27: Safety and Efficacy of Alteplase in Ischemic Stroke Patients > 80 Years of Age in the Extended Time WindowStretz C, Mac Grory B, Fakhri N, Boyanpally A, Asad S, Modak J, Effendi M, Kucher O, Owusu K, Yaghi S, Nouh A, Reznik M, Burton T, Cutting S, Sacchetti D, El JAMAL S, Madsen T, Falcone G, Petersen N, Furie K, gilmore E. Abstract P27: Safety and Efficacy of Alteplase in Ischemic Stroke Patients > 80 Years of Age in the Extended Time Window Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p27.
  • Abstract 117: Fixed Compared to Autoregulation-oriented Blood Pressure Thresholds After Mechanical Thrombectomy for Ischemic StrokePetersen N, Silverman A, Strander S, Kodali S, Wang A, Sansing L, Schindler J, Falcone G, Gilmore E, Jasne A, Cord B, Hebert R, Johnson M, Matouk C, Sheth K. Abstract 117: Fixed Compared to Autoregulation-oriented Blood Pressure Thresholds After Mechanical Thrombectomy for Ischemic Stroke Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.117.
  • Abstract 57: Deployment of Portable, Bedside, Low-Field Magnetic Resonance Imaging for Evaluation of Stroke PatientsCahn B, Shah J, Dyvorne H, O'Halloran R, Poole M, Yuen M, Mazurek M, Ward A, Payabvash S, Beekman R, Brown S, Falcone G, Gobeske K, Petersen N, Jasne A, Sharma R, Schindler J, Sansing L, Gilmore E, Wira C, Matouk C, Sze G, Rosen M, Kimberly W, Sheth K. Abstract 57: Deployment of Portable, Bedside, Low-Field Magnetic Resonance Imaging for Evaluation of Stroke Patients Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.57.
  • Abstract TMP89: Impaired Cerebral Autoregulation Increases Risk of Worse Outcome After Endovascular Thrombectomy in Stroke Patients With High Blood Pressure VariabilityNguyen C, Silverman A, Wang A, Kodali S, Strander S, Kimmel A, Peshwe K, De Havenon A, Gilmore E, Matouk C, Sansing L, Schindler J, Sheth K, Petersen N. Abstract TMP89: Impaired Cerebral Autoregulation Increases Risk of Worse Outcome After Endovascular Thrombectomy in Stroke Patients With High Blood Pressure Variability Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tmp89.
  • Abstract WP413: Portable, Bedside, Point of Care Magnetic Resonance Imaging in an Intensive Care Setting for Intracranial HemorrhageCahn B, Shah J, By S, Welch E, Sacolick L, Yuen M, Mazurek M, Wira C, Leasure A, Matouk C, Ward A, Payabvash S, Beekman R, Brown S, Falcone G, Gobeske K, Petersen N, Jasne A, Sharma R, Schindler J, Sansing L, Gilmore E, Sze G, Rosen M, Kimberly W, Sheth K. Abstract WP413: Portable, Bedside, Point of Care Magnetic Resonance Imaging in an Intensive Care Setting for Intracranial Hemorrhage Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wp413.
  • Deviation From Personalized Blood Pressure Targets Is Associated With Worse Outcome After Subarachnoid HemorrhageSilverman A, Kodali S, Strander S, Gilmore EJ, Kimmel A, Wang A, Cord B, Falcone G, Hebert R, Matouk C, Sheth KN, Petersen NH. Deviation From Personalized Blood Pressure Targets Is Associated With Worse Outcome After Subarachnoid Hemorrhage Stroke 2019, 50: 2729-2737. PMID: 31495332, PMCID: PMC6756936, DOI: 10.1161/strokeaha.119.026282.
  • Deviation from Dynamic and Personalized Optimal Blood Pressure Targets is Associated With Worse Functional Outcomes After Aneurysmal Subarachnoid HemorrhageSilverman A, Kodali S, Strander S, Gilmore E, Kimmel A, Wang A, Cord B, Falcone G, Hebert R, Matouk C, Sheth K, Petersen N. Deviation from Dynamic and Personalized Optimal Blood Pressure Targets is Associated With Worse Functional Outcomes After Aneurysmal Subarachnoid Hemorrhage Neurosurgery 2019, 66: 310-186. DOI: 10.1093/neuros/nyz310_186.
  • Early Prognostication of 1-Year Outcome After Subarachnoid Hemorrhage: The FRESH Score ValidationWitsch J, Kuohn L, Hebert R, Cord B, Sansing L, Gilmore EJ, Hwang DY, Petersen N, Falcone GJ, Matouk C, Sheth KN. Early Prognostication of 1-Year Outcome After Subarachnoid Hemorrhage: The FRESH Score Validation Journal Of Stroke And Cerebrovascular Diseases 2019, 28: 104280. PMID: 31326270, DOI: 10.1016/j.jstrokecerebrovasdis.2019.06.038.
  • Comparison of machine learning models for seizure prediction in hospitalized patientsStruck AF, Rodriguez‐Ruiz A, Osman G, Gilmore EJ, Haider HA, Dhakar MB, Schrettner M, Lee JW, Gaspard N, Hirsch LJ, Westover MB, Consortium C. Comparison of machine learning models for seizure prediction in hospitalized patients Annals Of Clinical And Translational Neurology 2019, 6: 1239-1247. PMID: 31353866, PMCID: PMC6649418, DOI: 10.1002/acn3.50817.
  • Decreases in Blood Pressure During Thrombectomy Are Associated With Larger Infarct Volumes and Worse Functional OutcomePetersen NH, Ortega-Gutierrez S, Wang A, Lopez GV, Strander S, Kodali S, Silverman A, Zheng-Lin B, Dandapat S, Sansing LH, Schindler JL, Falcone GJ, Gilmore EJ, Amin H, Cord B, Hebert RM, Matouk C, Sheth KN. Decreases in Blood Pressure During Thrombectomy Are Associated With Larger Infarct Volumes and Worse Functional Outcome Stroke 2019, 50: 1797-1804. PMID: 31159701, PMCID: PMC6787912, DOI: 10.1161/strokeaha.118.024286.
  • Abstract WP223: Ischemic and Hemorrhagic Stroke in Native AmericansKing Z, Beekman R, Chu S, Leasure A, Orgrass H, Gilmore E, Sansing L, Matouk C, Sheth K, Falcone G. Abstract WP223: Ischemic and Hemorrhagic Stroke in Native Americans Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.wp223.
  • Abstract 147: Individualized Blood Pressure Management After Subarachnoid Hemorrhage Using Real-time Autoregulation Monitoring: A Pilot Study Using NIRS and ICP-derived Limits of AutoregulationSilverman A, Wang A, Kodali S, Strander S, Cord B, Hebert R, Matouk C, Gilmore E, Sheth K, Petersen N. Abstract 147: Individualized Blood Pressure Management After Subarachnoid Hemorrhage Using Real-time Autoregulation Monitoring: A Pilot Study Using NIRS and ICP-derived Limits of Autoregulation Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.147.
  • Abstract 95: Exceeding Personalized Blood Pressure Targets After Endovascular Stroke Therapy is Associated With Hemorrhagic Transformation and Worse Functional OutcomePetersen N, Wang A, Strander S, Kodali S, Silverman A, Gilmore E, Sansing L, Schindler J, Hebert R, Cord B, Matouk C, Sheth K. Abstract 95: Exceeding Personalized Blood Pressure Targets After Endovascular Stroke Therapy is Associated With Hemorrhagic Transformation and Worse Functional Outcome Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.95.
  • 777Heck C, Owusu K, Ammar A, Alimi O, Gilmore E. 777 Critical Care Medicine 2019, 47: 367. DOI: 10.1097/01.ccm.0000551526.29723.6c.
  • History of Intracranial Hemorrhage Is Associated with In-Hospital Mortality in Ischemic Stroke Patients Treated with Intravenous ThrombolyticsSommaruga S, Chu S, Hwang D, Dearborn J, Sansing L, Cord B, Santarosa C, Samarth G, Petersen N, Gilmore E, Schindler J, Bijlenga P, Schaller K, Matouk C, Sheth K, Falcone G. History of Intracranial Hemorrhage Is Associated with In-Hospital Mortality in Ischemic Stroke Patients Treated with Intravenous Thrombolytics Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660745.
  • F80. Seizures and hyperexcitable EEG patterns in spontaneous deep intraparenchymal hemorrhageSheikh Z, Stretz C, Maciel C, Dhakar M, Hirsch L, Gilmore E. F80. Seizures and hyperexcitable EEG patterns in spontaneous deep intraparenchymal hemorrhage Clinical Neurophysiology 2018, 129: e96-e97. DOI: 10.1016/j.clinph.2018.04.243.
  • S18. Hypotension after ketamine administration for refractory status epilepticus in patients at risk of shockSheikh Z, Owusu K, Ammar A, Landreneau M, Heck C, Gilmore E. S18. Hypotension after ketamine administration for refractory status epilepticus in patients at risk of shock Clinical Neurophysiology 2018, 129: e149. DOI: 10.1016/j.clinph.2018.04.378.
  • T62. Bilateral independent periodic discharges are associated with electrographic seizures and poor outcome: A case-control studyOsman G, Rahangdale R, Britton J, Gilmore E, Haider H, Hantus S, Herlopian A, Hocker S, Lee J, Legros B, Punia V, Rampal N, Szaflarski J, Wallace A, Westover M, Hirsch L, Gaspard N. T62. Bilateral independent periodic discharges are associated with electrographic seizures and poor outcome: A case-control study Clinical Neurophysiology 2018, 129: e25-e26. DOI: 10.1016/j.clinph.2018.04.063.
  • S96. EEG reactivity testing practices for cardiac arrest coma prognostication in North AmericaAmorim E, Gaspard N, Gilmore E, Hahn C, Abend N, Herman S, Hirsch L, Lee J, Cash S, Westover M. S96. EEG reactivity testing practices for cardiac arrest coma prognostication in North America Clinical Neurophysiology 2018, 129: e178. DOI: 10.1016/j.clinph.2018.04.456.
  • EEG Monitoring in the Medical ICUDhakar M, Hantus S, Gilmore E. EEG Monitoring in the Medical ICU 2018 DOI: 10.1891/9780826168627.0014.
  • Abstract TMP14: Thrombolysis in Ischemic Stroke Patients with Prior History of Intracranial HemorrhageChu S, Sommaruga S, Hwang D, Dearborn J, Sansing L, Matouk C, Samarth G, Petersen N, Gilmore E, Schindler J, Sheth K, Falcone G. Abstract TMP14: Thrombolysis in Ischemic Stroke Patients with Prior History of Intracranial Hemorrhage Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.tmp14.
  • Abstract TP277: The Neurointensivists’ Role in Management of Cerebral Venous Sinus ThrombosisStretz C, Ghoshal S, Marcolini E, Hwang D, Petersen N, Schindler J, Sheth K, Falcone G, Gilmore E. Abstract TP277: The Neurointensivists’ Role in Management of Cerebral Venous Sinus Thrombosis Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.tp277.
  • Abstract TP331: Plasma IL-6 Levels are Independently Associated With Functional Outcome and Markers of Secondary Injury in Spontaneous Intracerebral HemorrhageLeasure A, Steinschneider A, Falcone G, Gilmore E, Sansing L, Sheth K. Abstract TP331: Plasma IL-6 Levels are Independently Associated With Functional Outcome and Markers of Secondary Injury in Spontaneous Intracerebral Hemorrhage Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.tp331.
  • Abstract 35: Hyperexcitability and Seizures in Primary Intraventricular HemorrhageStretz C, Sheikh Z, Maciel C, Sheth K, Hirsch L, Gilmore E. Abstract 35: Hyperexcitability and Seizures in Primary Intraventricular Hemorrhage Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.35.
  • 775Effendi M, Kucher O, Stretz C, Owusu K, Petersen N, Gilmore E. 775 Critical Care Medicine 2018, 46: 374. DOI: 10.1097/01.ccm.0000528789.23433.2c.
  • 49 Management of Postoperative SeizuresGrory B, Hirsch L, Gilmore E, Sheth K. 49 Management of Postoperative Seizures 2018, 497-507. DOI: 10.1016/b978-0-323-32106-8.00049-2.
  • Ictal-Interictal Continuum: When to Worry About the Continuous Electroencephalography PatternCormier J, Maciel CB, Gilmore EJ. Ictal-Interictal Continuum: When to Worry About the Continuous Electroencephalography Pattern Seminars In Respiratory And Critical Care Medicine 2017, 38: 793-806. PMID: 29262437, DOI: 10.1055/s-0037-1607987.
  • Disruption of Brain–Heart Coupling in SepsisAdmiraal MM, Gilmore EJ, Van Putten MJAM, Zaveri HP, Hirsch LJ, Gaspard N. Disruption of Brain–Heart Coupling in Sepsis Journal Of Clinical Neurophysiology 2017, 34: 413-420. PMID: 28520632, DOI: 10.1097/wnp.0000000000000381.
  • Seizures and Status EpilepticusHarris C, Gilmore E. Seizures and Status Epilepticus 2017, 201-221. DOI: 10.1007/978-3-319-48669-7_12.
  • Intracerebral Hemorrhage with Intraventricular Extension—Getting the Prognosis Right EarlyStretz C, Gao C, Greer DM, Loomis C, Gilmore EJ, Kundishora AJ, Matouk CC, Hwang DY. Intracerebral Hemorrhage with Intraventricular Extension—Getting the Prognosis Right Early Frontiers In Neurology 2017, 8: 418. PMID: 28861039, PMCID: PMC5562676, DOI: 10.3389/fneur.2017.00418.
  • Functional Improvement Among Intracerebral Hemorrhage (ICH) Survivors up to 12 Months Post-injurySreekrishnan A, Leasure AC, Shi FD, Hwang DY, Schindler JL, Petersen NH, Gilmore EJ, Kamel H, Sansing LH, Greer DM, Sheth KN. Functional Improvement Among Intracerebral Hemorrhage (ICH) Survivors up to 12 Months Post-injury Neurocritical Care 2017, 27: 326-333. PMID: 28685394, PMCID: PMC5700855, DOI: 10.1007/s12028-017-0425-4.
  • Abstract TP338: Differences Between the Modified Rankin Scale and Barthel Index in Measuring Intracerebral Hemorrhage Recovery at 12 MonthsSreekrishnan A, Leasure A, Zhou S, Amin H, Petersen N, Hwang D, Schindler J, Gilmore E, Sansing L, Greer D, Sheth K. Abstract TP338: Differences Between the Modified Rankin Scale and Barthel Index in Measuring Intracerebral Hemorrhage Recovery at 12 Months Stroke 2017, 48 DOI: 10.1161/str.48.suppl_1.tp338.
  • Status EpilepticusGilmore E, Nourollahzadeh E. Status Epilepticus 2016, 23-33. DOI: 10.1007/978-3-319-33341-0_3.
  • Review of the Utility of Prophylactic Anticonvulsant Use in Critically Ill Patients With Intracerebral HemorrhageGilmore EJ, Maciel CB, Hirsch LJ, Sheth KN. Review of the Utility of Prophylactic Anticonvulsant Use in Critically Ill Patients With Intracerebral Hemorrhage Stroke 2016, 47: 2666-2672. PMID: 27608820, DOI: 10.1161/strokeaha.116.012410.
  • Aneurysmal subarachnoid hemorrhage and severe, catheter-induced vasospasm associated with excessive consumption of a caffeinated energy drinkGrant RA, Cord BJ, Kuzomunhu L, Sheth K, Gilmore E, Matouk CC. Aneurysmal subarachnoid hemorrhage and severe, catheter-induced vasospasm associated with excessive consumption of a caffeinated energy drink Interventional Neuroradiology 2016, 22: 674-678. PMID: 27481912, PMCID: PMC5564359, DOI: 10.1177/1591019916660868.
  • Interrater Agreement for Consensus Definitions of Delayed Ischemic Events After Aneurysmal Subarachnoid HemorrhageZafar SF, Westover MB, Gaspard N, Gilmore EJ, Foreman BP, O'Connor KL, Rosenthal ES. Interrater Agreement for Consensus Definitions of Delayed Ischemic Events After Aneurysmal Subarachnoid Hemorrhage Journal Of Clinical Neurophysiology 2016, 33: 235-240. PMID: 27258447, PMCID: PMC4894325, DOI: 10.1097/wnp.0000000000000276.
  • Seizures and Epileptiform Patterns in SAH and Their Relation to OutcomesMaciel CB, Gilmore EJ. Seizures and Epileptiform Patterns in SAH and Their Relation to Outcomes Journal Of Clinical Neurophysiology 2016, 33: 183-195. PMID: 27258441, DOI: 10.1097/wnp.0000000000000268.
  • Critical Care Management of Intracerebral HemorrhageMorawo AO, Gilmore EJ. Critical Care Management of Intracerebral Hemorrhage Seminars In Neurology 2016, 36: 225-232. PMID: 27214697, DOI: 10.1055/s-0036-1581991.
  • Intracerebral Hemorrhage Location and Functional Outcomes of Patients: A Systematic Literature Review and Meta-AnalysisSreekrishnan A, Dearborn JL, Greer DM, Shi FD, Hwang DY, Leasure AC, Zhou SE, Gilmore EJ, Matouk CC, Petersen NH, Sansing LH, Sheth KN. Intracerebral Hemorrhage Location and Functional Outcomes of Patients: A Systematic Literature Review and Meta-Analysis Neurocritical Care 2016, 25: 384-391. PMID: 27160888, DOI: 10.1007/s12028-016-0276-4.
  • Understanding and Managing the Ictal-Interictal Continuum in Neurocritical CareSivaraju A, Gilmore EJ. Understanding and Managing the Ictal-Interictal Continuum in Neurocritical Care Current Treatment Options In Neurology 2016, 18: 8. PMID: 26874841, DOI: 10.1007/s11940-015-0391-0.
  • Clinical Correlates and Prognostic Significance of Lateralized Periodic Discharges in Patients Without Acute or Progressive Brain InjurySainju RK, Manganas LN, Gilmore EJ, Petroff OA, Rampal N, Hirsch LJ, Gaspard N. Clinical Correlates and Prognostic Significance of Lateralized Periodic Discharges in Patients Without Acute or Progressive Brain Injury Journal Of Clinical Neurophysiology 2015, 32: 495-500. PMID: 26200591, DOI: 10.1097/wnp.0000000000000206.
  • Status epilepticus epidemiology—tracking a moving targetGilmore EJ, Hirsch LJ. Status epilepticus epidemiology—tracking a moving target Nature Reviews Neurology 2015, 11: 377-378. PMID: 26100743, DOI: 10.1038/nrneurol.2015.104.
  • Prognostication of post-cardiac arrest coma: early clinical and electroencephalographic predictors of outcomeSivaraju A, Gilmore EJ, Wira CR, Stevens A, Rampal N, Moeller JJ, Greer DM, Hirsch LJ, Gaspard N. Prognostication of post-cardiac arrest coma: early clinical and electroencephalographic predictors of outcome Intensive Care Medicine 2015, 41: 1264-1272. PMID: 25940963, DOI: 10.1007/s00134-015-3834-x.
  • Acute brain failure in severe sepsis: a prospective study in the medical intensive care unit utilizing continuous EEG monitoringGilmore EJ, Gaspard N, Choi HA, Cohen E, Burkart KM, Chong DH, Claassen J, Hirsch LJ. Acute brain failure in severe sepsis: a prospective study in the medical intensive care unit utilizing continuous EEG monitoring Intensive Care Medicine 2015, 41: 686-694. PMID: 25763756, DOI: 10.1007/s00134-015-3709-1.
  • Time Course and Predictors of Neurological Deterioration After Intracerebral HemorrhageLord AS, Gilmore E, Choi HA, Mayer SA. Time Course and Predictors of Neurological Deterioration After Intracerebral Hemorrhage Stroke 2015, 46: 647-652. PMID: 25657190, PMCID: PMC4739782, DOI: 10.1161/strokeaha.114.007704.
  • Electroencephalogram Monitoring of VasospasmGilmore E, Gaspard N, Hirsch L. Electroencephalogram Monitoring of Vasospasm 2015, 62-62. DOI: 10.5005/jp/books/12423_10.
  • Medical Management of VasospasmMarcolini E, Gilmore E. Medical Management of Vasospasm 2015, 55-55. DOI: 10.5005/jp/books/12423_9.
  • O23: Uncoupling between heart rate and EEG in sepsisAdmiraal M, Gilmore E, Hirsch L, Zaveri H, Gaspard N. O23: Uncoupling between heart rate and EEG in sepsis Clinical Neurophysiology 2014, 125: s35. DOI: 10.1016/s1388-2457(14)50128-9.
  • Improving ascertainment and communication of prognosis in intracerebral hemorrhageGilmore EJ, Sheth KN. Improving ascertainment and communication of prognosis in intracerebral hemorrhage Critical Care 2013, 17: 1021. PMID: 24321182, PMCID: PMC4059379, DOI: 10.1186/cc13144.
  • Assessment of Brain Death in the Neurocritical Care UnitHwang DY, Gilmore EJ, Greer DM. Assessment of Brain Death in the Neurocritical Care Unit Neurosurgery Clinics Of North America 2013, 24: 469-482. PMID: 23809039, DOI: 10.1016/j.nec.2013.02.003.
  • Impact of Prolonged Periodic Epileptiform Discharges on Coma PrognosisOng C, Gilmore E, Claassen J, Foreman B, Mayer SA. Impact of Prolonged Periodic Epileptiform Discharges on Coma Prognosis Neurocritical Care 2012, 17: 39-44. PMID: 22700361, DOI: 10.1007/s12028-012-9728-7.
  • Pearls & Oy-stersKo S, Choi HA, Gilmore E, Schmidt JM, Claassen J, Lee K, Mayer SA, Badjatia N. Pearls & Oy-sters Neurology 2012, 78: e36-e38. PMID: 22311932, PMCID: PMC3280057, DOI: 10.1212/wnl.0b013e318245d270.
  • Acute Effects of Nimodipine on Cerebral Vasculature and Brain Metabolism in High Grade Subarachnoid Hemorrhage PatientsChoi HA, Ko SB, Chen H, Gilmore E, Carpenter AM, Lee D, Claassen J, Mayer SA, Schmidt JM, Lee K, Connelly ES, Paik M, Badjatia N. Acute Effects of Nimodipine on Cerebral Vasculature and Brain Metabolism in High Grade Subarachnoid Hemorrhage Patients Neurocritical Care 2012, 16: 363-367. PMID: 22262041, DOI: 10.1007/s12028-012-9670-8.
  • Prevention of Shivering During Therapeutic Temperature Modulation: The Columbia Anti-Shivering ProtocolChoi HA, Ko SB, Presciutti M, Fernandez L, Carpenter AM, Lesch C, Gilmore E, Malhotra R, Mayer SA, Lee K, Claassen J, Schmidt JM, Badjatia N. Prevention of Shivering During Therapeutic Temperature Modulation: The Columbia Anti-Shivering Protocol Neurocritical Care 2011, 14: 389-394. PMID: 21210305, DOI: 10.1007/s12028-010-9474-7.
  • Seizures and CNS HemorrhageGilmore E, Choi HA, Hirsch LJ, Claassen J. Seizures and CNS Hemorrhage The Neurologist 2010, 16: 165-175. PMID: 20445426, DOI: 10.1097/nrl.0b013e3181c7cd0b.
  • Traumatic brain injury.Gilmore E, Karceski S. Traumatic brain injury. Neurology 2010, 74: e28-31. PMID: 20177116, DOI: 10.1212/WNL.0b013e3181d55f8a.
  • Fatal Case of Deer Tick Virus EncephalitisTavakoli NP, Wang H, Dupuis M, Hull R, Ebel GD, Gilmore EJ, Faust PL. Fatal Case of Deer Tick Virus Encephalitis New England Journal Of Medicine 2009, 360: 2099-2107. PMID: 19439744, PMCID: PMC2847876, DOI: 10.1056/nejmoa0806326.

Clinical Trials

ConditionsStudy Title
Diseases of the Cardiovascular SystemBiomarker and Edema Attenuation in IntraCerebral Hemorrhage (BEACH)
Diseases of the Nervous SystemBrain Oxygen Optimization in Severe TBI, Phase 3 (BOOST3)
Diseases of the Cardiovascular System; Diseases of the Nervous SystemAnticoagulation for Stroke Prevention and Recovery After ICH (ASPIRE)
Diseases of the Nervous SystemMulti-arm Optimization of Stroke Thrombolysis (MOST)
Diseases of the Nervous SystemPhase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large Hemispheric Infarction (CHARM)
Diseases of the Nervous SystemTransforming Acute Stroke Detection through Real Time Neurological Monitoring
Diseases of the Cardiovascular SystemMultimodal Outcome CHAracterization (MOCHA) in comatose cardiac arrest patients
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