2024
Percutaneous Coronary Revascularization Strategies After Myocardial Infarction A Systematic Review and Network Meta-Analysis
Reddy R, Howard J, Jamil Y, Madhavan M, Nanna M, Lansky A, Leon M, Ahmad Y. Percutaneous Coronary Revascularization Strategies After Myocardial Infarction A Systematic Review and Network Meta-Analysis. Journal Of The American College Of Cardiology 2024, 84: 276-294. PMID: 38986670, DOI: 10.1016/j.jacc.2024.04.051.Peer-Reviewed Original ResearchConceptsRelative riskCardiovascular mortalityMyocardial infarctionMultivessel coronary artery diseaseAll-cause mortalityAdverse cardiac eventsST-segment elevation myocardial infarctionComplete revascularizationCoronary artery diseaseBayesian network meta-analysesMortality reductionA systematic reviewNetwork meta-analysesElevation myocardial infarctionSystematic reviewMeta-analysesCardiac eventsArtery diseasePrimary outcomeNetwork meta-analysisRevascularization strategyMeta-analysisHead-to-head trialsCoronary revascularization strategyAcute kidney injuryIntravascular imaging-guided coronary drug-eluting stent implantation: an updated network meta-analysis
Stone G, Christiansen E, Ali Z, Andreasen L, Maehara A, Ahmad Y, Landmesser U, Holm N. Intravascular imaging-guided coronary drug-eluting stent implantation: an updated network meta-analysis. The Lancet 2024, 403: 824-837. PMID: 38401549, DOI: 10.1016/s0140-6736(23)02454-6.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionIntravascular imaging guidanceTarget vessel myocardial infarctionIntravascular imaging-guided percutaneous coronary interventionAngiography-guided percutaneous coronary interventionImaging-guided percutaneous coronary interventionOptical coherence tomographyAngiography guidanceTarget lesion revascularisationImage guidanceMeta-analysisTarget lesion failureInternational Prospective Register of Systematic ReviewsSystematic reviewProspective Register of Systematic ReviewsMyocardial infarctionDrug-eluting stentsCardiac deathInternational Prospective RegisterLesion failureStent thrombosisRisk of cardiac deathRisk of target lesion failureStudy-level dataIntravascular ultrasound-guided percutaneous coronary interventionIntravascular Imaging–Guided Versus Angiography‐Guided Percutaneous Coronary Intervention: A Systematic Review and Meta‐Analysis of Randomized Trials
Sreenivasan J, Reddy R, Jamil Y, Malik A, Chamie D, Howard J, Nanna M, Mintz G, Maehara A, Ali Z, Moses J, Chen S, Chieffo A, Colombo A, Leon M, Lansky A, Ahmad Y. Intravascular Imaging–Guided Versus Angiography‐Guided Percutaneous Coronary Intervention: A Systematic Review and Meta‐Analysis of Randomized Trials. Journal Of The American Heart Association 2024, 13: e031111. PMID: 38214263, PMCID: PMC10926835, DOI: 10.1161/jaha.123.031111.Peer-Reviewed Original ResearchConceptsAdverse cardiac eventsPercutaneous coronary interventionAngiography-guided percutaneous coronary interventionTarget vessel revascularizationTarget-lesion revascularizationCardiac eventsCardiac deathImaging-guided percutaneous coronary interventionWeighted mean follow-up durationMeta-analysisPrimary outcomeMean follow-up durationStent thrombosisMeta-analysis of randomized trialsStudy-level meta-analysisComplex lesion subsetsIntravascular imagingAll-cause deathRandom-effects meta-analysisStandard of careIntention-to-treat principleUpdates of clinical guidelinesMixed-effects meta-regressionComplex percutaneous coronary interventionIntravascular imaging-guided percutaneous coronary intervention
2021
Renal Denervation for Hypertension A Systematic Review and Meta-Analysis of Randomized, Blinded, Placebo-Controlled Trials
Ahmad Y, Francis D, Bhatt D, Howard J. Renal Denervation for Hypertension A Systematic Review and Meta-Analysis of Randomized, Blinded, Placebo-Controlled Trials. JACC Cardiovascular Interventions 2021, 14: 2614-2624. PMID: 34743900, DOI: 10.1016/j.jcin.2021.09.020.Peer-Reviewed Original ResearchConceptsPlacebo-controlled trialRenal denervationAntihypertensive medicationsBlood pressureMeta-analysisCatheter-based renal sympathetic denervationEffect of renal denervationRandomized placebo-controlled trialDrug-resistant hypertensionConcomitant antihypertensive medicationOffice blood pressureRenal sympathetic denervationAmbulatory systolic blood pressureRandom-effects meta-analysisSystolic blood pressureEffects of denervationAntihypertensive medication useMagnitude of benefitOffice systolicPlacebo-controlledEfficacy outcomesSympathetic denervationAntihypertensive agentsAmbulatory systolicEligible trialsTCT-452 Renal Denervation for the Treatment of Hypertension: A Systematic Review and Meta-Analysis of Randomized, Blinded, Placebo-Controlled Trials
Ahmad Y, Francis D, Bhatt D, Howard J. TCT-452 Renal Denervation for the Treatment of Hypertension: A Systematic Review and Meta-Analysis of Randomized, Blinded, Placebo-Controlled Trials. Journal Of The American College Of Cardiology 2021, 78: b186. DOI: 10.1016/j.jacc.2021.09.1305.Peer-Reviewed Original Research