2023
Single vs. multiple operators for chronic total occlusion percutaneous coronary interventions: From the PROGRESS‐CTO Registry
Karacsonyi J, Alaswad K, Krestyaninov O, Karmpaliotis D, Kirtane A, Ali Z, McEntegart M, Masoumi A, Poomipanit P, Jaffer F, Khatri J, Choi J, Patel M, Koutouzis M, Tsiafoutis I, Gorgulu S, Sheikh A, Elbarouni B, Jaber W, ElGuindy A, Yeh R, Kostantinis S, Simsek B, Rangan B, Mastrodemos O, Vemmou E, Nikolakopoulos I, Ungi I, Rafeh N, Goktekin O, Burke M, Brilakis E, Sandoval Y. Single vs. multiple operators for chronic total occlusion percutaneous coronary interventions: From the PROGRESS‐CTO Registry. Catheterization And Cardiovascular Interventions 2023, 101: 543-552. PMID: 36695421, DOI: 10.1002/ccd.30564.Peer-Reviewed Original ResearchConceptsCTO-PCIChronic total occlusion (CTO) percutaneous coronary interventionAir kerma radiation dosePercutaneous coronary intervention outcomesChronic total occlusion interventionLow MACE ratePROGRESS-CTO RegistryProspective global registryProcedural success ratePercutaneous coronary interventionHigh technical successRisk of complicationsMO casesCTO PCI casesMACE rateCoronary interventionMulticenter registryPatient ageMultivariable analysisProcedural successContrast volumeGlobal RegistryTechnical successProcedural outcomesPCI cases
2022
External validation of the PROGRESS-CTO complication risk scores: Individual patient data pooled analysis of 3 registries
Simsek B, Tajti P, Carlino M, Ojeda S, Pan M, Rinfret S, Vemmou E, Kostantinis S, Nikolakopoulos I, Karacsonyi J, Dens J, Agostoni P, Alaswad K, Megaly M, Avran A, Choi J, Jaffer F, Doshi D, Karmpaliotis D, Khatri J, Knaapen P, La Manna A, Spratt J, Tanabe M, Walsh S, Mastrodemos O, Allana S, Rempakos A, Rangan B, Goktekin O, Gorgulu S, Poommipanit P, Kearney K, Lombardi W, Grantham J, Mashayekhi K, Brilakis E, Azzalini L. External validation of the PROGRESS-CTO complication risk scores: Individual patient data pooled analysis of 3 registries. International Journal Of Cardiology 2022, 375: 14-20. PMID: 36565956, DOI: 10.1016/j.ijcard.2022.12.036.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsPercutaneous coronary interventionCTO percutaneous coronary interventionComplication risk scoreIndividual patient dataComplication scoreRisk scorePrior coronary artery bypass graft surgeryCoronary artery bypass graft surgeryChronic total occlusion (CTO) percutaneous coronary interventionArtery bypass graft surgeryObserved complication rateAdverse cardiovascular eventsBypass graft surgeryPatient dataJ-CTO scoreRisk of complicationsGood discriminative performanceBlunt stumpMACE rateMACE scoresCardiovascular eventsGraft surgeryCoronary interventionComplication rateValidation of the OPEN-CLEAN Chronic Total Occlusion Percutaneous Coronary Intervention Perforation Score in a Multicenter Registry
Simsek B, Carlino M, Ojeda S, Pan M, Rinfret S, Vemmou E, Kostantinis S, Nikolakopoulos I, Karacsonyi J, Quadros A, Dens J, Abi Rafeh N, Agostoni P, Alaswad K, Avran A, Belli K, Choi J, Elguindy A, Jaffer F, Doshi D, Karmpaliotis D, Khatri J, Khelimskii D, Knaapen P, La Manna A, Krestyaninov O, Lamelas P, Padilla L, de Oliveira P, Spratt J, Tanabe M, Walsh S, Goktekin O, Gorgulu S, Mastrodemos O, Allana S, Rangan B, Kearney K, Lombardi W, Grantham J, Hirai T, Brilakis E, Azzalini L. Validation of the OPEN-CLEAN Chronic Total Occlusion Percutaneous Coronary Intervention Perforation Score in a Multicenter Registry. The American Journal Of Cardiology 2022, 188: 30-35. PMID: 36462272, DOI: 10.1016/j.amjcard.2022.11.023.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionCTO percutaneous coronary interventionCoronary artery perforationArtery perforationPerforation riskPrevious coronary artery bypass graftChronic total occlusion (CTO) percutaneous coronary interventionCoronary artery bypass graftModerate-severe calcificationUnfavorable angiographic characteristicsArtery bypass graftProximal cap ambiguityBlunt stumpAngiographic characteristicsMulticenter registryCoronary interventionFeared complicationBypass graftTechnical successPatientsPerforationGood calibrationCharacteristic curveScoresRiskOutcomes and challenges of the provisional stenting technique: Insights from the PROGRESS‐BIFURCATION registry
Simsek B, Kostantinis S, Karacsonyi J, Allana S, Vemmou E, Nikolakopoulos I, Burke M, Garcia S, Wang Y, Chavez I, Gössl M, Sorajja P, Mooney M, Poulose A, Sandoval Y, Traverse J, Rangan B, Brilakis E. Outcomes and challenges of the provisional stenting technique: Insights from the PROGRESS‐BIFURCATION registry. Catheterization And Cardiovascular Interventions 2022, 100: 749-755. PMID: 36121014, DOI: 10.1002/ccd.30401.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionTwo-stent strategyProvisional stentingProcedural successTechnical successHospital major adverse cardiovascular eventsMajor adverse cardiovascular eventsAdverse cardiovascular eventsLower technical successProspective global registrySimilar procedural successProvisional stenting techniqueAngiographic characteristicsCardiovascular eventsCoronary interventionDiameter stenosisGlobal RegistryDistal lesionsProcedural outcomesSB involvementSB lesion lengthBifurcation lesionsSide branch diameterStenting techniquesStentingPrimary vs Secondary Retrograde Approach in Chronic Total Occlusion Percutaneous Coronary Interventions.
Kostantinis S, Alaswad K, Karmpaliotis D, Jaffer F, Jaber W, Nicholson W, Rinfret S, Khatri J, Poommipanit P, Karacsonyi J, Simsek B, Vemmou E, Nikolakopoulos I, Koutouzis M, Tsiafoutis I, Riley R, Sheikh A, Patel M, Gorgulu S, ElGuindy A, Goktekin O, Abi Rafeh N, Rangan B, Garcia S, Burke M, Brilakis E. Primary vs Secondary Retrograde Approach in Chronic Total Occlusion Percutaneous Coronary Interventions. Journal Of Invasive Cardiology 2022, 34: e672-e677. PMID: 35969839.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionCoronary chronic total occlusionsRetrograde approachRetrograde CTO-PCICoronary interventionCTO-PCIHospital major adverse cardiac eventsCoronary artery bypass graft surgeryChronic total occlusion (CTO) percutaneous coronary interventionMajor adverse cardiac eventsMajor adverse event rateArtery bypass graft surgeryCTO percutaneous coronary interventionAdverse cardiac eventsBypass graft surgeryAdverse event ratesProcedural success rateVentricular ejection fractionChronic total occlusionPROGRESS CTO scoresAngiographic characteristicsGraft surgeryCardiac eventsEjection fractionProcedural successPercutaneous coronary intervention of chronic total occlusions involving a bifurcation: Insights from the PROGRESS-CTO registry
Nikolakopoulos I, Vemmou E, Karacsonyi J, Alaswad K, Karmpaliotis D, Abi Rafeh N, Schimmel D, Benzuly K, Flaherty J, Poommipanit P, ElGuindy A, Burke M, Brilakis E. Percutaneous coronary intervention of chronic total occlusions involving a bifurcation: Insights from the PROGRESS-CTO registry. Hellenic Journal Of Cardiology 2022, 66: 80-83. PMID: 35247542, DOI: 10.1016/j.hjc.2022.02.005.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionDistal capProximal capCoronary interventionCoronary artery bypass graft surgery ratesChronic total occlusion (CTO) percutaneous coronary interventionCTO percutaneous coronary interventionLower technical success rateLower technical successPROGRESS-CTO RegistryTechnical success rateChronic total occlusionPCI registrySurgery ratesProcedural dataTotal occlusionTechnical successJ-CTOHigh riskSuccess rateRegistryTwo-thirdsInterventionLimited studiesBifurcation locationChallenges and outcomes of the double kissing crush stenting technique: Insights from the PROGRESS‐BIFURCATION registry
Simsek B, Kostantinis S, Karacsonyi J, Vemmou E, Nikolakopoulos I, Assali M, Burke M, Garcia S, Wang Y, Chavez I, Goessl M, Sorajja P, Mooney M, Poulose A, Traverse J, Rangan B, Brilakis E. Challenges and outcomes of the double kissing crush stenting technique: Insights from the PROGRESS‐BIFURCATION registry. Catheterization And Cardiovascular Interventions 2022, 99: 1038-1044. PMID: 35195331, DOI: 10.1002/ccd.30135.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionDK crushBifurcation lesionsCoronary interventionDouble kissingHospital major adverse cardiovascular eventsMajor adverse cardiovascular eventsBifurcation percutaneous coronary interventionProspective global registryAdverse cardiovascular eventsDouble kissing crushSide branchesAngiographic characteristicsCardiovascular eventsNew guidewireArtery lesionsComplication rateProcedural successExcellent outcomesGlobal RegistryTechnical successProcedural outcomesCrush techniqueLesionsBifurcation stenting
2021
Procedural and In-Hospital Outcomes of Chronic Total Occlusion Percutaneous Coronary Interventions in Patients With Acute Myocardial Infarction: Insights From a Prospective Multicenter International Registry.
Arman P, Basir M, Gupta A, Choi J, Khatri J, Jaffer F, Poomipanit P, Forouzandeh F, Koutouzis M, Tsiafoutis I, Patel M, Mahmud E, Vemmou E, Nikolakopoulos I, Karacsonyi J, ElGuindy A, Goktekin O, Abi Rafeh N, Brilakis E, Alaswad K. Procedural and In-Hospital Outcomes of Chronic Total Occlusion Percutaneous Coronary Interventions in Patients With Acute Myocardial Infarction: Insights From a Prospective Multicenter International Registry. Journal Of Invasive Cardiology 2021, 33: e670-e676. PMID: 34473071.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionPercutaneous coronary interventionNon-AMI patientsChronic total occlusion (CTO) percutaneous coronary interventionCTO-PCIAMI patientsCoronary interventionProcedural successTechnical successMyocardial infarctionHospital major adverse cardiovascular event (MACE) rateMajor adverse cardiovascular event ratesAdverse cardiovascular event ratesMulticenter international registrySimilar technical successIn-Hospital OutcomesCardiovascular event ratesProcedural success rateVentricular ejection fractionHemodynamic support devicesNon-CTO lesionsAntegrade wire escalationHospital MACEAngiographic characteristicsHospital outcomesDistal Radial Access in Chronic Total Occlusion Percutaneous Coronary Intervention: Insights From the PROGRESS-CTO Registry.
Nikolakopoulos I, Patel T, Jefferson B, Sheikh A, Jaber W, Samady H, Khatri J, Yeh R, Tamez H, Koutouzis M, Tsiafoutis I, Jaffer F, Doing A, Dattilo P, Uretsky B, Toma C, Elbarouni B, Alaswad K, Choi J, Lembo N, Parikh M, Kirtane A, Ali Z, Omer M, Vemmou E, Xenogiannis I, Karacsonyi J, Rangan B, Abdullah S, Banerjee S, Garcia S, Burke M, Brilakis E, Karmpaliotis D. Distal Radial Access in Chronic Total Occlusion Percutaneous Coronary Intervention: Insights From the PROGRESS-CTO Registry. Journal Of Invasive Cardiology 2021, 33: e717-e722. PMID: 34433693.Peer-Reviewed Original ResearchMeSH KeywordsCoronary OcclusionHumansPercutaneous Coronary InterventionRegistriesRisk FactorsTreatment OutcomeConceptsDistal radial accessChronic total occlusion (CTO) percutaneous coronary interventionPercutaneous coronary interventionRadial accessCoronary interventionPRA groupProcedural successCTO-PCIAir kerma radiation doseAdverse cardiac eventsPROGRESS-CTO RegistryJ-CTO scoreRisk of complicationsSimilar procedural successPROGRESS CTO scoresDRA accessMulticenter registryCardiac eventsFemoral accessTechnical successConcomitant useProcedural characteristicsDRA groupRadiation doseComplicationsOutcomes of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) according to race: Insights from the PROGRESS-CTO registry
Vemmou E, Nikolakopoulos I, Karacsonyi J, Kostantinis S, Rangan B, Baechler C, Garcia S, Burke M, Alaswad K, Brilakis E. Outcomes of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) according to race: Insights from the PROGRESS-CTO registry. Hellenic Journal Of Cardiology 2021, 64: 90-92. PMID: 34311103, DOI: 10.1016/j.hjc.2021.07.007.Peer-Reviewed Original ResearchComparison of Outcomes of Patients with vs without Previous Coronary Artery Bypass Graft Surgery Presenting with ST-Segment Elevation Acute Myocardial Infarction
Karacsonyi J, Schmidt CW, Okeson BK, Garcia S, Henry TD, Nikolakopoulos I, Vemmou E, Xenogiannis I, Sharkey S, Aguirre FV, Tannenbaum M, Burke M, Goessl M, Sorajja P, Traverse J, Wang YL, Brilakis ES. Comparison of Outcomes of Patients with vs without Previous Coronary Artery Bypass Graft Surgery Presenting with ST-Segment Elevation Acute Myocardial Infarction. The American Journal Of Cardiology 2021, 154: 33-40. PMID: 34243937, DOI: 10.1016/j.amjcard.2021.05.041.Peer-Reviewed Original ResearchConceptsPrevious coronary bypass graft surgeryST-segment elevation acute myocardial infarctionCoronary bypass graft surgeryElevation acute myocardial infarctionPrevious CABG patientsAcute myocardial infarctionCABG patientsBaseline characteristicsMyocardial infarctionMajor cardiac adverse eventsBypass graft surgeryCardiac adverse eventsOutcomes of patientsSaphenous vein graftsKaplan-Meier methodLong-term outcomesLog-rank testComparison of outcomesSTEMI registryGraft surgerySTEMI patientsAdverse eventsMost patientsPrimary outcomeTerm outcomesChronic total occlusion percutaneous coronary intervention during the COVID-19 pandemic: Insights from the PROGRESS-CTO registry
Vemmou E, Alaswad K, Khatri JJ, Khelimskii D, Krestyaninov O, Poommipanit P, Karacsonyi J, Nikolakopoulos I, Garcia S, Brilakis ES. Chronic total occlusion percutaneous coronary intervention during the COVID-19 pandemic: Insights from the PROGRESS-CTO registry. Hellenic Journal Of Cardiology 2021, 62: 372-373. PMID: 34098128, PMCID: PMC8178534, DOI: 10.1016/j.hjc.2021.05.005.Peer-Reviewed Original ResearchIn-Stent CTO Percutaneous Coronary Intervention Individual Patient Data Pooled Analysis of 4 Multicenter Registries
Vemmou E, Quadros AS, Dens JA, Rafeh NA, Agostoni P, Alaswad K, Avran A, Belli KC, Carlino M, Choi JW, El-Guindy A, Jaffer FA, Karmpaliotis D, Khatri JJ, Khelimskii D, Knaapen P, La Manna A, Krestyaninov O, Lamelas P, Ojeda S, Padilla L, Pan M, Piccaro de Oliveira P, Rinfret S, Spratt JC, Tanabe M, Walsh S, Nikolakopoulos I, Karacsonyi J, Rangan BV, Brilakis ES, Azzalini L. In-Stent CTO Percutaneous Coronary Intervention Individual Patient Data Pooled Analysis of 4 Multicenter Registries. JACC Cardiovascular Interventions 2021, 14: 1308-1319. PMID: 34052151, DOI: 10.1016/j.jcin.2021.04.003.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsDe novo chronic total occlusionsChronic total occlusionPercutaneous coronary interventionHospital major adverse cardiovascular eventsCTO percutaneous coronary interventionMyocardial infarctionLong-term major adverse cardiovascular eventsStent restenosis chronic total occlusionsCoronary artery bypass graft surgeryOutcomes of PCIMean J-CTO scoreArtery bypass graft surgeryAdverse cardiovascular eventsBypass graft surgeryDe novo groupJ-CTO scorePatient-level dataCause deathPercutaneous CoronaryAngiographic characteristicsCardiovascular eventsGraft surgeryMulticenter registryVessel revascularizationLaser for balloon uncrossable and undilatable chronic total occlusion interventions
Karacsonyi J, Alaswad K, Choi JW, Vemmou E, Nikolakopoulos I, Poommipanit P, Rafeh NA, ElGuindy A, Ungi I, Egred M, Brilakis ES. Laser for balloon uncrossable and undilatable chronic total occlusion interventions. International Journal Of Cardiology 2021, 336: 33-37. PMID: 34022321, DOI: 10.1016/j.ijcard.2021.05.015.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionCTO percutaneous coronary interventionChronic total occlusion (CTO) PCIMajor adverse cardiac eventsSimilar major complication ratesComplex percutaneous coronary interventionChronic total occlusion interventionOutcomes of balloonAdverse cardiac eventsMajor complication rateStent restenotic lesionsLaser useAngiographic characteristicsCardiac eventsComplication rateCoronary interventionPatient ageProcedural successCTO lesionsRestenotic lesionsSimilar incidenceProcedural outcomesUndilatable lesionsLesionsSuccess rateTHE IMPACT OF ANNUAL OPERATOR VOLUME ON THE OUTCOMES OF CHRONIC TOTAL OCCLUSION PERCUTANEOUS CORONARY INTERVENTION
Karacsonyi J, Tsiafoutis I, Alaswad K, Khatri J, Choi J, Karmpaliotis D, ElGuindy A, Sheikh A, Jaber W, Elbarouni B, Jaffer F, Poomipanit P, Chandwaney R, Krestianinov O, Uretsky B, Patel M, Toma C, Yeh R, Vemmou E, Nikolakopoulos I, Xenogiannis I, Rangan B, Ungi I, Brilakis E, Koutouzis M. THE IMPACT OF ANNUAL OPERATOR VOLUME ON THE OUTCOMES OF CHRONIC TOTAL OCCLUSION PERCUTANEOUS CORONARY INTERVENTION. Journal Of Invasive Cardiology 2021, 77: 958. PMID: 35969838, DOI: 10.1016/s0735-1097(21)02317-2.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionChronic total occlusion (CTO) percutaneous coronary interventionOperator volumeCoronary interventionHigher J-CTO scoreMajor cardiac adverse eventsHigh technical success rateAnnual operator volumeCardiac adverse eventsHigher lesion complexityMajor complication rateJ-CTO scoreTechnical success rateHigh technical successHigh-volume operatorsCTO PCI casesLow-volume operatorsProximal cap ambiguityProximal vessel tortuosityMulticenter registryAdverse eventsComplication ratePatient ageProcedural successMultivariable analysisPredicting Technical Success of Chronic Total Occlusion Percutaneous Coronary Intervention
Karacsonyi J, Stanberry L, Alaswad K, Krestyaninov O, Choi JW, Rangan BV, Nikolakopoulos I, Vemmou E, Ungi I, Brilakis ES. Predicting Technical Success of Chronic Total Occlusion Percutaneous Coronary Intervention. Circulation Cardiovascular Interventions 2021, 14: e009860. PMID: 33423537, DOI: 10.1161/circinterventions.120.009860.Peer-Reviewed Original Research
2020
Impact of adherence to the hybrid algorithm for initial crossing strategy selection in chronic total occlusion percutaneous coronary intervention
Xenogiannis I, Alaswad K, Krestyaninov O, Khelimskii D, Khatri JJ, Choi JW, Jaffer FA, Patel M, Mahmud E, Doing AH, Dattilo P, Koutouzis M, Tsiafoutis I, Uretsky B, Jefferson BK, Patel T, Jaber W, Samady H, Sheikh AM, Yeh RW, Tamez H, Elbarouni B, Love MP, Abi Rafeh N, Maalouf A, Fadi AJ, Toma C, Shah AR, Chandwaney RH, Omer M, Megaly MS, Vemmou E, Nikolakopoulos I, Rangan BV, Garcia S, Abdullah S, Banerjee S, Burke MN, Karmpaliotis D, Brilakis ES. Impact of adherence to the hybrid algorithm for initial crossing strategy selection in chronic total occlusion percutaneous coronary intervention. Revista Española De Cardiología (English Edition) 2020, 74: 1023-1031. PMID: 33189636, DOI: 10.1016/j.rec.2020.09.009.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionChronic total occlusion (CTO) percutaneous coronary interventionCTO percutaneous coronary interventionJ-CTO scoreImpact of adherenceTechnical successCoronary interventionHospital major adverse cardiac eventsHospital major adverse eventsMean J-CTO scorePrior percutaneous coronary interventionMajor adverse cardiac eventsConcordant groupLarge multicenter registryLower technical successAdverse cardiac eventsCoronary artery bypassMajor adverse eventsOverall technical successPrior myocardial infarctionHigh technical successCTO-PCI successArtery bypassMulticenter registryAdverse eventsPatient Radiation Dose During Chronic Total Occlusion Percutaneous Coronary Intervention
Vemmou E, Alaswad K, Khatri JJ, Nikolakopoulos I, Karacsonyi J, Xenogiannis I, Karmpaliotis D, Garcia S, Burke MN, Brilakis ES. Patient Radiation Dose During Chronic Total Occlusion Percutaneous Coronary Intervention. Circulation Cardiovascular Interventions 2020, 13: e009412. PMID: 32972204, DOI: 10.1161/circinterventions.120.009412.Peer-Reviewed Original ResearchOutcomes of Percutaneous Coronary Intervention for In-Stent Chronic Total Occlusions Insights From the PROGRESS-CTO Registry
Vemmou E, Alaswad K, Karmpaliotis D, Krestyaninov O, Khelimskii D, Xenogiannis I, Nikolakopoulos I, Rangan BV, Brilakis ES. Outcomes of Percutaneous Coronary Intervention for In-Stent Chronic Total Occlusions Insights From the PROGRESS-CTO Registry. JACC Cardiovascular Interventions 2020, 13: 1969-1971. PMID: 32819493, DOI: 10.1016/j.jcin.2020.05.003.Peer-Reviewed Original ResearchEquipment utilization in chronic total occlusion percutaneous coronary interventions: Insights from the PROGRESS‐CTO registry
Nikolakopoulos I, Choi JW, Alaswad K, Khatri JJ, Krestyaninov O, Khelimskii D, Yeh RW, Jaffer FA, Toma C, Patel M, Mahmud E, Lembo NJ, Parikh M, Kirtane AJ, Ali ZA, Gkargkoulas F, Uretsky B, Sheikh AM, Vemmou E, Xenogiannis I, Rangan BV, Garcia S, Abdullah S, Banerjee S, Burke MN, Brilakis ES, Karmpaliotis D. Equipment utilization in chronic total occlusion percutaneous coronary interventions: Insights from the PROGRESS‐CTO registry. Catheterization And Cardiovascular Interventions 2020, 97: 658-667. PMID: 32597031, DOI: 10.1002/ccd.29106.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionChronic total occlusion (CTO) percutaneous coronary interventionCTO percutaneous coronary interventionCoronary interventionHigh-complexity lesionsPolymer-jacketed guidewiresPROGRESS-CTO RegistryAntegrade guidewireMedian numberMicrocatheterGuidewireFielder XTInterventionRetrograde casesPatientsAntegradeRegistryLesions