2024
Percutaneous Coronary Revascularization Strategies After Myocardial Infarction A Systematic Review and Network Meta-Analysis
Reddy R, Howard J, Jamil Y, Madhavan M, Nanna M, Lansky A, Leon M, Ahmad Y. Percutaneous Coronary Revascularization Strategies After Myocardial Infarction A Systematic Review and Network Meta-Analysis. Journal Of The American College Of Cardiology 2024, 84: 276-294. PMID: 38986670, DOI: 10.1016/j.jacc.2024.04.051.Peer-Reviewed Original ResearchConceptsRelative riskCardiovascular mortalityMyocardial infarctionMultivessel coronary artery diseaseAll-cause mortalityAdverse cardiac eventsST-segment elevation myocardial infarctionComplete revascularizationCoronary artery diseaseBayesian network meta-analysesMortality reductionA systematic reviewNetwork meta-analysesElevation myocardial infarctionSystematic reviewMeta-analysesCardiac eventsArtery diseasePrimary outcomeNetwork meta-analysisRevascularization strategyMeta-analysisHead-to-head trialsCoronary revascularization strategyAcute kidney injuryIntravascular imaging-guided coronary drug-eluting stent implantation: an updated network meta-analysis
Stone G, Christiansen E, Ali Z, Andreasen L, Maehara A, Ahmad Y, Landmesser U, Holm N. Intravascular imaging-guided coronary drug-eluting stent implantation: an updated network meta-analysis. The Lancet 2024, 403: 824-837. PMID: 38401549, DOI: 10.1016/s0140-6736(23)02454-6.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionIntravascular imaging guidanceTarget vessel myocardial infarctionIntravascular imaging-guided percutaneous coronary interventionAngiography-guided percutaneous coronary interventionImaging-guided percutaneous coronary interventionOptical coherence tomographyAngiography guidanceTarget lesion revascularisationImage guidanceMeta-analysisTarget lesion failureInternational Prospective Register of Systematic ReviewsSystematic reviewProspective Register of Systematic ReviewsMyocardial infarctionDrug-eluting stentsCardiac deathInternational Prospective RegisterLesion failureStent thrombosisRisk of cardiac deathRisk of target lesion failureStudy-level dataIntravascular ultrasound-guided percutaneous coronary intervention
2023
Complex Percutaneous Coronary Intervention Outcomes in Older Adults
Hanna J, Wang S, Kochar A, Park D, Damluji A, Henry G, Ahmad Y, Curtis J, Nanna M. Complex Percutaneous Coronary Intervention Outcomes in Older Adults. Journal Of The American Heart Association 2023, 12: e029057. PMID: 37776222, PMCID: PMC10727245, DOI: 10.1161/jaha.122.029057.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCoronary Artery DiseaseHemorrhageHumansMyocardial InfarctionMyocardial IschemiaPercutaneous Coronary InterventionTreatment OutcomeConceptsNoncomplex percutaneous coronary interventionsComplex percutaneous coronary interventionStable ischemic heart diseasePercutaneous coronary interventionIschemic heart diseaseTarget lesion revascularizationEvent-free survivalHeart diseaseOlder adultsCause deathLesion revascularizationClinical characteristicsElective percutaneous coronary interventionPercutaneous coronary intervention outcomesWorse event-free survivalMedical therapy useCox regression modelLarge health systemNoncardiac comorbiditiesRevascularization riskCoronary interventionTherapy useClinical outcomesDisease featuresLower riskDeferred Versus Performed Revascularization for Left Main Coronary Disease With Hemodynamic Significance
Warisawa T, Cook C, Ahmad Y, Howard J, Seligman H, Rajkumar C, Toya T, Doi S, Nakajima A, Nakayama M, Vera-Urquiza R, Yuasa S, Sato T, Kikuta Y, Kawase Y, Nishina H, Al-Lamee R, Sen S, Lerman A, Matsuo H, Akashi Y, Escaned J, Davies J. Deferred Versus Performed Revascularization for Left Main Coronary Disease With Hemodynamic Significance. Circulation Cardiovascular Interventions 2023, 16: e012700. PMID: 37339234, DOI: 10.1161/circinterventions.122.012700.Peer-Reviewed Original ResearchMeSH KeywordsCoronary Artery BypassCoronary Artery DiseaseDeathHumansMyocardial InfarctionMyocardial RevascularizationPercutaneous Coronary InterventionTreatment OutcomeConceptsIschemia-driven target lesion revascularizationTarget lesion revascularizationLeft main stemCoronary artery diseaseStable coronary artery diseaseLong-term clinical outcomesPrimary end pointSecondary end pointsInstantaneous wave-free ratioLesion revascularizationArtery diseaseClinical outcomesMyocardial infarctionEnd pointRevascularization deferralCardiac deathLeft main coronary diseaseMain coronary artery diseaseBaseline clinical characteristicsComposite of deathContemporary clinical outcomesInternational multicenter registryMain coronary diseaseNonfatal myocardial infarctionMedian followPhysiology-guided PCI versus CABG for left main coronary artery disease: insights from the DEFINE-LM registry
Warisawa T, Cook C, Kawase Y, Howard J, Ahmad Y, Seligman H, Rajkumar C, Toya T, Doi S, Nakajima A, Tanigaki T, Omori H, Nakayama M, Vera-Urquiza R, Yuasa S, Sato T, Kikuta Y, Nishina H, Al-Lamee R, Sen S, Lerman A, Akashi Y, Escaned J, Matsuo H, Davies J. Physiology-guided PCI versus CABG for left main coronary artery disease: insights from the DEFINE-LM registry. Cardiovascular Intervention And Therapeutics 2023, 38: 287-298. PMID: 37017899, PMCID: PMC10247826, DOI: 10.1007/s12928-023-00932-z.Peer-Reviewed Original ResearchConceptsUnprotected left main coronary diseasePercutaneous coronary interventionInstantaneous wave-free ratioMain coronary artery diseaseNon-fatal myocardial infarctionCoronary artery bypassCoronary artery diseasePrimary endpointCause deathLesion revascularizationArtery bypassSYNTAX scoreCoronary interventionArtery diseaseClinical outcomesMyocardial infarctionIschemia-driven target lesion revascularizationLeft main coronary artery diseaseArt percutaneous coronary interventionLeft main coronary diseaseLower cardiovascular event ratesMajor adverse cardiovascular eventsLong-term clinical outcomesPropensity scorePhysiology-guided percutaneous coronary intervention
2020
Response by Ahmad et al to Letter Regarding Article “Effects of Percutaneous Coronary Intervention on Death and Myocardial Infarction Stratified by Stable and Unstable Coronary Artery Disease: A Meta-Analysis of Randomized Controlled Trials”
Ahmad Y, Howard JP, Francis DP. Response by Ahmad et al to Letter Regarding Article “Effects of Percutaneous Coronary Intervention on Death and Myocardial Infarction Stratified by Stable and Unstable Coronary Artery Disease: A Meta-Analysis of Randomized Controlled Trials”. Circulation Cardiovascular Quality And Outcomes 2020, 13: e006862. PMID: 32482084, DOI: 10.1161/circoutcomes.120.006862.Peer-Reviewed Original ResearchMeSH KeywordsCoronary Artery DiseaseHumansMyocardial InfarctionPercutaneous Coronary InterventionRandomized Controlled Trials as TopicResponse by Ahmad et al to Letter Regarding Article, “Effects of Percutaneous Coronary Intervention on Death and Myocardial Infarction Stratified by Stable and Unstable Coronary Artery Disease: A Meta-Analysis of Randomized Controlled Trials”
Ahmad Y, Howard JP, Francis DP. Response by Ahmad et al to Letter Regarding Article, “Effects of Percutaneous Coronary Intervention on Death and Myocardial Infarction Stratified by Stable and Unstable Coronary Artery Disease: A Meta-Analysis of Randomized Controlled Trials”. Circulation Cardiovascular Quality And Outcomes 2020, 13: e006642. PMID: 32283970, DOI: 10.1161/circoutcomes.120.006642.Peer-Reviewed Original ResearchMeSH KeywordsCoronary Artery DiseaseHumansMyocardial InfarctionPercutaneous Coronary InterventionRandomized Controlled Trials as Topic
2015
Intra-aortic Balloon Pump Therapy for Acute Myocardial Infarction: A Meta-analysis
Ahmad Y, Sen S, Shun-Shin MJ, Ouyang J, Finegold JA, Al-Lamee RK, Davies JER, Cole GD, Francis DP. Intra-aortic Balloon Pump Therapy for Acute Myocardial Infarction: A Meta-analysis. JAMA Internal Medicine 2015, 175: 931-939. PMID: 25822657, DOI: 10.1001/jamainternmed.2015.0569.Peer-Reviewed Original ResearchMeSH KeywordsHumansIntra-Aortic Balloon PumpingMyocardial InfarctionObservational Studies as TopicRandomized Controlled Trials as TopicConceptsAcute myocardial infarctionIntra-aortic balloon pump therapyUse of IABPMyocardial infarctionObservational studyCardiogenic shockPump therapyIntra-aortic balloon pumpNon-IABP groupThirty-day mortalityAcute coronary syndromeEligible observational studiesRisk of biasIABP efficacyIABP useEligible RCTsCochrane riskCoronary syndromeIABP therapyBalloon pumpBias toolCochrane LibraryClinical trialsRisk factorsSTUDY SELECTIONA new method of applying randomised control study data to the individual patient: A novel quantitative patient-centred approach to interpreting composite end points
Ahmad Y, Nijjer S, Cook CM, El-Harasis M, Graby J, Petraco R, Kotecha T, Baker CS, Malik IS, Bellamy MF, Sethi A, Mikhail GW, Al-Bustami M, Khan M, Kaprielian R, Foale RA, Mayet J, Davies JE, Francis DP, Sen S. A new method of applying randomised control study data to the individual patient: A novel quantitative patient-centred approach to interpreting composite end points. International Journal Of Cardiology 2015, 195: 216-224. PMID: 26048380, DOI: 10.1016/j.ijcard.2015.05.109.Peer-Reviewed Original ResearchConceptsIndividual patientsComposite end pointCoronary artery bypassDrug-eluting stentsPatient-centered approachSignificant differencesPatient preference dataPatient-centered metricsArtery bypassCardiac catheterisationComposite endpointPatient preferencesPatientsTrial dataEnd pointTrial resultsEndpointMACECABGSurgeryTrialsStructured toolDeathStudy dataRevascularisation