2023
Diagnosis, Classification, and Management Strategies for Mitral Annular Calcification A Heart Valve Collaboratory Position Statement
Guerrero M, Grayburn P, Smith R, Sorajja P, Wang D, Ahmad Y, Blusztein D, Cavalcante J, Tang G, Ailawadi G, Lim D, Blanke P, Eleid M, Kaneko T, Thourani V, Bapat V, Mack M, Leon M, George I. Diagnosis, Classification, and Management Strategies for Mitral Annular Calcification A Heart Valve Collaboratory Position Statement. JACC Cardiovascular Interventions 2023, 16: 2195-2210. PMID: 37758378, DOI: 10.1016/j.jcin.2023.06.044.Peer-Reviewed Original ResearchConceptsMitral annular calciumTranscatheter mitral valve interventionsMitral valve interventionAnnular calciumConcomitant comorbiditiesValve replacementValve interventionClinical featuresValvular dysfunctionStaging systemTreatment optionsAdvanced ageInterventional cardiologistsCardiac surgeonsPosition statementImaging cardiologistsCardiologistsTechnical considerationsAnatomical featuresTranscatheterComorbiditiesMitralPatientsDysfunctionDiagnosis
2021
Usefulness of Computed Tomography to Predict Mitral Stenosis After Transcatheter Mitral Valve Edge-to-Edge Repair
Kaewkes D, Patel V, Ochiai T, Flint N, Ahmad Y, Kim I, Koseki K, Sharma R, Joseph J, Yoon SH, Chakravarty T, Nakamura M, Makar M, Makkar R. Usefulness of Computed Tomography to Predict Mitral Stenosis After Transcatheter Mitral Valve Edge-to-Edge Repair. The American Journal Of Cardiology 2021, 153: 109-118. PMID: 34210503, DOI: 10.1016/j.amjcard.2021.05.025.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCardiac CatheterizationEchocardiographyEchocardiography, TransesophagealFemaleHumansMaleMiddle AgedMitral ValveMitral Valve AnnuloplastyMitral Valve InsufficiencyMitral Valve StenosisMultidetector Computed TomographyPostoperative ComplicationsPreoperative PeriodRisk AssessmentConceptsMitral valve orifice areaMitraClip implantationMitral stenosisMDCT parametersPredictive valuePre-discharge transthoracic echocardiographyTranscatheter mitral valve edgeTranscatheter mitral valve interventionsMitral valve interventionMitral valve edgeMitral annulus areaOptimal cutoff valueValve orifice areaCharacteristic curve analysisMitral annulus diameterNegative predictive valuePositive predictive valueTransthoracic echocardiographyConsecutive patientsValve interventionMitraClip procedureMitral regurgitationAP diameterAnnulus diameterEdge repair
2020
Difference in functional assessment of individual stenosis severity in serial coronary lesions between resting and hyperemic pressure-wire pullback: Insights from the GIFT registry
Warisawa T, Howard JP, Kawase Y, Tanigaki T, Omori H, Cook CM, Ahmad Y, Francis DP, Akashi YJ, Matsuo H, Davies JE. Difference in functional assessment of individual stenosis severity in serial coronary lesions between resting and hyperemic pressure-wire pullback: Insights from the GIFT registry. International Journal Of Cardiology 2020, 312: 10-15. PMID: 32376416, DOI: 10.1016/j.ijcard.2020.05.001.Peer-Reviewed Original ResearchConceptsFractional flow reserveInstantaneous wave-free ratioCoronary lesionsPressure-wire pullbackCoronary artery lesionsPhysiological assessmentArtery lesionsConsecutive patientsCoronary stenosisHemodynamic significanceWave-free periodFlow reserveHemodynamic interactionSerial lesionsSerial stenosesFunctional assessmentStenosis severityLesionsStenosisHyperemic conditionsStatistical differenceWhole cardiac cycleReference standardCardiac cyclePredominancePer-Vessel Level Analysis of Fractional Flow Reserve and Instantaneous Wave-Free Ratio Discordance ― Insights From the AJIP Registry ―
Warisawa T, Cook CM, Seligman H, Howard JP, Ahmad Y, Rajkumar C, Doi S, Nakayama M, Tanigaki T, Omori H, Nakajima A, Yamanaka F, Goto S, Yakuta Y, Karube K, Uetani T, Kikuta Y, Shiono Y, Kawase Y, Nishina H, Nakamura S, Escaned J, Akashi YJ, Matsuo H, Davies JE. Per-Vessel Level Analysis of Fractional Flow Reserve and Instantaneous Wave-Free Ratio Discordance ― Insights From the AJIP Registry ―. Circulation Journal 2020, 84: 1034-1038. PMID: 32321880, DOI: 10.1253/circj.cj-19-0785.Peer-Reviewed Original ResearchHow Do Fractional Flow Reserve, Whole-Cycle PdPa, and Instantaneous Wave-Free Ratio Correlate With Exercise Coronary Flow Velocity During Exercise-Induced Angina?
Cook CM, Howard JP, Ahmad Y, Shun-Shin MJ, Sethi A, Clesham GJ, Tang KH, Nijjer SS, Kelly PA, Davies JR, Malik IS, Kaprielian R, Mikhail G, Petraco R, Warisawa T, Al-Janabi F, Karamasis GV, Mohdnazri S, Gamma R, de Waard GA, Al-Lamee R, Keeble TR, Mayet J, Sen S, Francis DP, Davies JE. How Do Fractional Flow Reserve, Whole-Cycle PdPa, and Instantaneous Wave-Free Ratio Correlate With Exercise Coronary Flow Velocity During Exercise-Induced Angina? Circulation Cardiovascular Interventions 2020, 13: e008460. PMID: 32200646, DOI: 10.1161/circinterventions.119.008460.Peer-Reviewed Original Research
2019
Determining the Predominant Lesion in Patients With Severe Aortic Stenosis and Coronary Stenoses
Ahmad Y, Vendrik J, Eftekhari A, Howard JP, Cook C, Rajkumar C, Malik I, Mikhail G, Ruparelia N, Hadjiloizou N, Nijjer S, Al-Lamee R, Petraco R, Warisawa T, Wijntjens GWM, Koch KT, van de Hoef T, de Waard G, Echavarria-Pinto M, Frame A, Sutaria N, Kanaganayagam G, Ariff B, Anderson J, Chukwuemeka A, Fertleman M, Koul S, Iglesias JF, Francis D, Mayet J, Serruys P, Davies J, Escaned J, van Royen N, Götberg M, Terkelsen C, Christiansen E, Piek JJ, Baan J, Sen S. Determining the Predominant Lesion in Patients With Severe Aortic Stenosis and Coronary Stenoses. Circulation Cardiovascular Interventions 2019, 12: e008263-e008263. PMID: 31752515, PMCID: PMC6924937, DOI: 10.1161/circinterventions.119.008263.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisBlood Flow VelocityCardiac CatheterizationCoronary Artery DiseaseCoronary CirculationCoronary StenosisCoronary VesselsEuropeFemaleHemodynamicsHumansMaleMicrocirculationPercutaneous Coronary InterventionPredictive Value of TestsRecovery of FunctionSeverity of Illness IndexTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsTranscatheter aortic valve implantationSevere aortic stenosisPercutaneous coronary interventionAortic stenosisCoronary artery diseaseCoronary stenosisIntermediate coronary stenosisCoronary diseaseCoronary interventionArtery diseaseCoronary microcirculationWave-free periodInstantaneous wave-free ratio valueConcomitant coronary artery diseaseConcomitant coronary diseaseAortic valve implantationInstantaneous wave-free ratioPhysiology-guided revascularizationExertional symptomsPost-TAVIHemodynamic improvementHemodynamic benefitsValve implantationCoronary lesionsMicrovascular resistancePhysiological Pattern of Disease Assessed by Pressure-Wire Pullback Has an Influence on Fractional Flow Reserve/Instantaneous Wave-Free Ratio Discordance
Warisawa T, Cook CM, Howard JP, Ahmad Y, Doi S, Nakayama M, Goto S, Yakuta Y, Karube K, Shun-Shin MJ, Petraco R, Sen S, Nijjer S, Lamee R, Ishibashi Y, Matsuda H, Escaned J, di Mario C, Francis DP, Akashi YJ, Davies JE. Physiological Pattern of Disease Assessed by Pressure-Wire Pullback Has an Influence on Fractional Flow Reserve/Instantaneous Wave-Free Ratio Discordance. Circulation Cardiovascular Interventions 2019, 12: e007494-e007494. PMID: 31084237, PMCID: PMC6553990, DOI: 10.1161/circinterventions.118.007494.Peer-Reviewed Original ResearchConceptsInstantaneous wave-free ratioFractional flow reservePressure-wire pullbackCoronary artery diseaseArtery diseaseCoronary lesionsHemodynamic significancePhysiological patternsInternational multicenter registryIntermediate coronary lesionsMedian fractional flow reserveMulticenter registryFlow reserveDiseaseLesionsCut pointsIFR measurementDiscordanceRegistryFactors
2018
Coronary Hemodynamics in Patients With Severe Aortic Stenosis and Coronary Artery Disease Undergoing Transcatheter Aortic Valve Replacement Implications for Clinical Indices of Coronary Stenosis Severity
Ahmad Y, Götberg M, Cook C, Howard JP, Malik I, Mikhail G, Frame A, Petraco R, Rajkumar C, Demir O, Iglesias JF, Bhindi R, Koul S, Hadjiloizou N, Gerber R, Ramrakha P, Ruparelia N, Sutaria N, Kanaganayagam G, Ariff B, Fertleman M, Anderson J, Chukwuemeka A, Francis D, Mayet J, Serruys P, Davies J, Sen S. Coronary Hemodynamics in Patients With Severe Aortic Stenosis and Coronary Artery Disease Undergoing Transcatheter Aortic Valve Replacement Implications for Clinical Indices of Coronary Stenosis Severity. JACC Cardiovascular Interventions 2018, 11: 2019-2031. PMID: 30154062, PMCID: PMC6197079, DOI: 10.1016/j.jcin.2018.07.019.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic Valve StenosisBlood Flow VelocityCardiac CatheterizationCoronary Artery DiseaseCoronary StenosisFemaleFractional Flow Reserve, MyocardialHemodynamicsHumansHyperemiaLondonMalePredictive Value of TestsReproducibility of ResultsSeverity of Illness IndexSwedenTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsSevere aortic stenosisTranscatheter aortic valve replacementCoronary artery diseaseCoronary stenosis severityAortic stenosisHyperemic coronary flowFractional flow reserveArtery diseaseCoronary flowStenosis severityWave-free periodClinical indicesHyperemic flowFlow reserveInstantaneous wave-free ratio valueIntracoronary pressureConcomitant coronary artery diseaseAortic valve replacementStenotic aortic valvesInstantaneous wave-free ratioPhasic coronary flowValve replacementHyperemic indexAortic valveCoronary pressureFractional Flow Reserve and Instantaneous Wave-Free Ratio as Predictors of the Placebo-Controlled Response to Percutaneous Coronary Intervention in Stable Single-Vessel Coronary Artery Disease: Physiology-Stratified Analysis of ORBITA
Al-Lamee R, Howard JP, Shun-Shin MJ, Thompson D, Dehbi HM, Sen S, Nijjer S, Petraco R, Davies J, Keeble T, Tang K, Malik IS, Cook C, Ahmad Y, Sharp ASP, Gerber R, Baker C, Kaprielian R, Talwar S, Assomull R, Cole G, Keenan NG, Kanaganayagam G, Sehmi J, Wensel R, Harrell FE, Mayet J, Thom SA, Davies JE, Francis DP. Fractional Flow Reserve and Instantaneous Wave-Free Ratio as Predictors of the Placebo-Controlled Response to Percutaneous Coronary Intervention in Stable Single-Vessel Coronary Artery Disease: Physiology-Stratified Analysis of ORBITA. Circulation 2018, 138: circulationaha.118.033801. PMID: 29789302, DOI: 10.1161/circulationaha.118.033801.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-1 Receptor AgonistsAgedAngina, StableCardiac CatheterizationCoronary AngiographyCoronary Artery DiseaseCoronary StenosisDobutamineEchocardiography, StressExercise TestExercise ToleranceFemaleFractional Flow Reserve, MyocardialHealth StatusHumansMaleMiddle AgedPercutaneous Coronary InterventionPredictive Value of TestsProgression-Free SurvivalQuality of LifeRecovery of FunctionSeverity of Illness IndexTime FactorsUnited KingdomConceptsPercutaneous coronary interventionInstantaneous wave-free ratioFractional flow reserveSingle-vessel coronary artery diseaseTreadmill exercise timeCoronary artery diseaseExercise timeEchocardiography scoreStable anginaCoronary interventionArtery diseaseFlow reserveCanadian Cardiovascular Society class IIEffect of PCISevere single-vessel diseaseSingle-vessel coronary diseaseMean fractional flow reserveAngina frequency scorePlacebo-controlled effectsPlacebo-controlled efficacyPlacebo-controlled trialTotal exercise timeSingle-vessel diseaseAngina severityEchocardiographic improvement
2017
Fractional Flow Reserve/Instantaneous Wave-Free Ratio Discordance in Angiographically Intermediate Coronary Stenoses An Analysis Using Doppler-Derived Coronary Flow Measurements
Cook CM, Jeremias A, Petraco R, Sen S, Nijjer S, Shun-Shin MJ, Ahmad Y, de Waard G, van de Hoef T, Echavarria-Pinto M, van Lavieren M, Lamee R, Kikuta Y, Shiono Y, Buch A, Meuwissen M, Danad I, Knaapen P, Maehara A, Koo BK, Mintz GS, Escaned J, Stone GW, Francis DP, Mayet J, Piek JJ, van Royen N, Davies JE. Fractional Flow Reserve/Instantaneous Wave-Free Ratio Discordance in Angiographically Intermediate Coronary Stenoses An Analysis Using Doppler-Derived Coronary Flow Measurements. JACC Cardiovascular Interventions 2017, 10: 2514-2524. PMID: 29268881, PMCID: PMC5743106, DOI: 10.1016/j.jcin.2017.09.021.Peer-Reviewed Original ResearchAgedBlood Flow VelocityCardiac CatheterizationCoronary AngiographyCoronary StenosisCoronary VesselsDatabases, FactualEchocardiography, DopplerFemaleFractional Flow Reserve, MyocardialHumansHyperemiaMaleMiddle AgedPredictive Value of TestsPrognosisReproducibility of ResultsRetrospective StudiesSeverity of Illness Index
2016
Quantification of the Effect of Pressure Wire Drift on the Diagnostic Performance of Fractional Flow Reserve, Instantaneous Wave-Free Ratio, and Whole-Cycle Pd/Pa
Cook CM, Ahmad Y, Shun-Shin MJ, Nijjer S, Petraco R, Al-Lamee R, Mayet J, Francis DP, Sen S, Davies JE. Quantification of the Effect of Pressure Wire Drift on the Diagnostic Performance of Fractional Flow Reserve, Instantaneous Wave-Free Ratio, and Whole-Cycle Pd/Pa. Circulation Cardiovascular Interventions 2016, 9: e002988. PMID: 27076571, PMCID: PMC4836560, DOI: 10.1161/circinterventions.115.002988.Peer-Reviewed Original Research