2022
Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis.
Kelshiker MA, Seligman H, Howard JP, Rahman H, Foley M, Nowbar AN, Rajkumar CA, Shun-Shin MJ, Ahmad Y, Sen S, Al-Lamee R, Petraco R. Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis. European Heart Journal 2022, 43: 1582-1593. PMID: 36282780, DOI: 10.1093/eurheartj/ehab775.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeCardiovascular SystemCoronary Artery DiseaseFractional Flow Reserve, MyocardialHumansMyocardial IschemiaPrognosisProportional Hazards ModelsConceptsMajor adverse cardiovascular eventsAbnormal coronary flow reserveCoronary flow reserveCause mortalityCoronary flowHigh incidenceHazard ratioFlow reserveAdverse cardiovascular eventsCoronary microvascular dysfunctionAcute coronary syndromeRandom-effects modelEstimate of effectCardiovascular eventsCardiovascular outcomesCoronary syndromeMicrovascular dysfunctionHeart failureHeart transplantClinical outcomesPatient groupRisk modificationHigh riskClinical practiceSystematic review
2021
Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis
Kelshiker MA, Seligman H, Howard JP, Rahman H, Foley M, Nowbar AN, Rajkumar CA, Shun-Shin MJ, Ahmad Y, Sen S, Al-Lamee R, Petraco R, Cole G, Hoole S, Paul D, Rigo F, Francis D, Mayet J. Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis. European Heart Journal 2021, 43: 1582-1593. PMID: 34849697, PMCID: PMC9020988, DOI: 10.1093/eurheartj/ehab775.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeCardiovascular SystemCoronary Artery DiseaseFractional Flow Reserve, MyocardialHumansMyocardial IschemiaPrognosisProportional Hazards ModelsConceptsMajor adverse cardiovascular eventsAbnormal coronary flow reserveCoronary flow reserveCause mortalityCoronary flowHigh incidenceHazard ratioFlow reserveAdverse cardiovascular eventsCoronary microvascular dysfunctionAcute coronary syndromeRandom-effects modelEstimate of effectCardiovascular eventsCardiovascular outcomesCoronary syndromeMicrovascular dysfunctionHeart failureHeart transplantClinical outcomesPatient groupRisk modificationHigh riskClinical practiceSystematic review
2020
Effects of Percutaneous Coronary Intervention on Death and Myocardial Infarction Stratified by Stable and Unstable Coronary Artery Disease
Chacko L, Howard J, Rajkumar C, Nowbar AN, Kane C, Mahdi D, Foley M, Shun-Shin M, Cole G, Sen S, Al-Lamee R, Francis DP, Ahmad Y. Effects of Percutaneous Coronary Intervention on Death and Myocardial Infarction Stratified by Stable and Unstable Coronary Artery Disease. Circulation Cardiovascular Quality And Outcomes 2020, 13: e006363-e006363. PMID: 32063040, PMCID: PMC7034389, DOI: 10.1161/circoutcomes.119.006363.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAdultAgedAged, 80 and overCause of DeathClinical Decision-MakingCoronary Artery DiseaseFemaleHumansMaleMiddle AgedNon-ST Elevated Myocardial InfarctionPercutaneous Coronary InterventionRandomized Controlled Trials as TopicRisk AssessmentRisk FactorsST Elevation Myocardial InfarctionTime FactorsTreatment OutcomeYoung AdultConceptsST-segment elevation myocardial infarctionStable coronary artery diseaseUnstable coronary artery diseasePercutaneous coronary interventionCoronary artery diseaseSegment elevation acute coronary syndromesAcute coronary syndromeMyocardial infarctionCardiac deathMultivessel diseaseCoronary syndromeCoronary interventionArtery diseaseBenefits of PCITrials of PCITreatment of CADCulprit-only revascularization strategyEarly percutaneous coronary interventionPrimary percutaneous coronary interventionPatients post-myocardial infarctionResidual coronary lesionsPrimary end pointComparative Health EffectivenessPost-myocardial infarctionImmediate revascularization