Resolving the paradox of randomised controlled trials and observational studies comparing multi-vessel angioplasty and culprit only angioplasty at the time of STEMI
Ahmad Y, Cook C, Shun-Shin M, Balu A, Keene D, Nijjer S, Petraco R, Baker CS, Malik IS, Bellamy MF, Sethi A, Mikhail GW, Al-Bustami M, Khan M, Kaprielian R, Foale RA, Mayet J, Davies JE, Francis DP, Sen S. Resolving the paradox of randomised controlled trials and observational studies comparing multi-vessel angioplasty and culprit only angioplasty at the time of STEMI. International Journal Of Cardiology 2016, 222: 1-8. PMID: 27448698, DOI: 10.1016/j.ijcard.2016.06.106.Peer-Reviewed Original ResearchConceptsHigh-risk patientsLarge observational studiesObservational studyResidual diseaseMulti-vessel coronary artery diseaseHigh mortalityPrimary percutaneous coronary interventionST-elevation myocardial infarctionPercutaneous coronary interventionCoronary artery diseaseReal-world patientsOptimal treatment strategyAllocation biasCoronary interventionCulprit arteryRisk patientsArtery diseaseMyocardial infarctionSmall RCTsWorld patientsTreatment strategiesPatientsEquivalent mortalitySTEMIMortality