2023
Cerebral Embolic Protection in Transcatheter Aortic Valve Replacement
Iskander M, Jamil Y, Forrest J, Madhavan M, Makkar R, Leon M, Lansky A, Ahmad Y. Cerebral Embolic Protection in Transcatheter Aortic Valve Replacement. Structural Heart 2023, 7: 100169. PMID: 37520138, PMCID: PMC10382985, DOI: 10.1016/j.shj.2023.100169.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementCerebral embolic protection devicesCerebral embolic protectionAortic valve replacementEmbolic protection devicesValve replacementEmbolic protectionSymptomatic severe aortic stenosisSevere aortic stenosisLow-risk patientsPredictors of strokeOccurrence of complicationsRisk of strokeRecent trial dataRelevant clinical studiesOverall evidence baseExpansion of TAVRFeared complicationAortic stenosisSurgical riskTreatment optionsWorse outcomesClinical studiesPatientsTrial dataCerebral Embolic Protection Devices During Transcatheter Aortic Valve Replacement: A Meta-analysis of Randomized Controlled Trials
Reddy R, Ahmad Y, Arnold A, Howard J. Cerebral Embolic Protection Devices During Transcatheter Aortic Valve Replacement: A Meta-analysis of Randomized Controlled Trials. Journal Of The Society For Cardiovascular Angiography & Interventions 2023, 2: 101031. PMID: 37780935, PMCID: PMC10533415, DOI: 10.1016/j.jscai.2023.101031.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementEmbolic protection devicesAortic valve replacementCause mortalityEnd pointValve replacementCerebral embolic protection devicesAcute kidney injuryPrimary end pointSafety end pointRandomized Controlled TrialsTotal lesion volumeSignificant differencesKidney injuryVascular complicationsFeared complicationControlled TrialsNew lesionsOngoing RCTsLesion volumeMeta-AnalysisStudy registrationSystematic reviewStrokeMeaningful reduction
2021
Meta-Analysis of Usefulness of Cerebral Embolic Protection During Transcatheter Aortic Valve Implantation
Ahmad Y, Howard JP. Meta-Analysis of Usefulness of Cerebral Embolic Protection During Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2021, 146: 69-73. PMID: 33556360, PMCID: PMC8082278, DOI: 10.1016/j.amjcard.2021.01.023.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationCerebral embolic protectionRisk of strokeAortic valve implantationEmbolic protectionValve implantationClinical outcomesNon-disabling strokePrimary end pointNew ischemic lesionsRandomized clinical trialsTotal lesion volumeSignificant differencesFeared complicationIschemic lesionsClinical trialsLesion volumeStroke rateNeuroimaging outcomesMeta-AnalysisSystematic reviewTrial dataStrokeEnd pointSignificant heterogeneity