Renal Denervation for Hypertension A Systematic Review and Meta-Analysis of Randomized, Blinded, Placebo-Controlled Trials
Ahmad Y, Francis D, Bhatt D, Howard J. Renal Denervation for Hypertension A Systematic Review and Meta-Analysis of Randomized, Blinded, Placebo-Controlled Trials. JACC Cardiovascular Interventions 2021, 14: 2614-2624. PMID: 34743900, DOI: 10.1016/j.jcin.2021.09.020.Peer-Reviewed Original ResearchConceptsPlacebo-controlled trialRenal denervationAntihypertensive medicationsBlood pressureMeta-analysisCatheter-based renal sympathetic denervationEffect of renal denervationRandomized placebo-controlled trialDrug-resistant hypertensionConcomitant antihypertensive medicationOffice blood pressureRenal sympathetic denervationAmbulatory systolic blood pressureRandom-effects meta-analysisSystolic blood pressureEffects of denervationAntihypertensive medication useMagnitude of benefitOffice systolicPlacebo-controlledEfficacy outcomesSympathetic denervationAntihypertensive agentsAmbulatory systolicEligible trials