2022
Imaging, Treatment Options, Patient Selection, and Outcome Considerations for Patients With Bicuspid Aortic Valve Disease
Ahmad Y, Agarwal V, Williams M, Wang D, Reardon M, Cavalcante J, Makkar R, Forrest J. Imaging, Treatment Options, Patient Selection, and Outcome Considerations for Patients With Bicuspid Aortic Valve Disease. Journal Of The Society For Cardiovascular Angiography & Interventions 2022, 1: 100506. DOI: 10.1016/j.jscai.2022.100506.Peer-Reviewed Original ResearchAortic valve replacementTranscatheter aortic valve replacementBicuspid aortic valve diseaseAortic valve diseaseValve replacementValve diseaseBAV diseaseSevere symptomatic aortic stenosisSurgical aortic valve replacementPivotal randomized trialsAortic valve surgerySymptomatic aortic stenosisRandomized clinical trialsValve surgeryHeart teamAortic stenosisSurgical riskPatient selectionRandomized trialsBicuspid valveSurgical approachTreatment optionsClinical trialsPatientsDiseaseClinical Research on Transcatheter Aortic Valve Replacement for Bicuspid Aortic Valve Disease: Principles, Challenges, and an Agenda for the Future
Ahmad Y, Madhavan M, Baron S, Forrest J, Borger M, Leipsic J, Cavalcante J, Wang D, McCarthy P, Szerlip M, Kapadia S, Makkar R, Mack M, Leon M, Cohen D. Clinical Research on Transcatheter Aortic Valve Replacement for Bicuspid Aortic Valve Disease: Principles, Challenges, and an Agenda for the Future. Structural Heart 2022, 7: 100102. PMID: 37275317, PMCID: PMC10236801, DOI: 10.1016/j.shj.2022.100102.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementBicuspid aortic valve diseaseSurgical aortic valve replacementAortic valve replacementAortic valve diseaseValve replacementClinical researchValve diseaseValvular heart diseaseDesign of RCTsProcedural therapiesProspective registryHeart diseaseExclusion criteriaRisk scorePatientsRCTsDiseaseCardiovascular communityMultidisciplinary workshopSelection biasTrialsInternational expertsPotential studiesRegistryCurrent Landscape and Future Directions of Coronary Revascularization in Patients With Heart Failure
Ahmad Y, Lansky AJ, Velazquez EJ. Current Landscape and Future Directions of Coronary Revascularization in Patients With Heart Failure. JAMA Cardiology 2022, 7: 577-578. PMID: 35476046, DOI: 10.1001/jamacardio.2022.0659.Peer-Reviewed Original ResearchMEDICAL THERAPY VS. REVASCULARIZATION IN LEFT MAIN CORONARY ARTERY DISEASE WITH PROVEN ISCHEMIA: INSIGHTS FROM THE DEFINE-LM REGISTRY
Warisawa T, Cook C, Kawase Y, Howard J, Nakayama M, Ahmad Y, Seligman H, Rajkumar C, Doi S, Nakajima A, Goto S, Vera-Urquiza R, Kikuta Y, Lerman A, Akashi Y, Escaned J, Matsuo H, Davies J. MEDICAL THERAPY VS. REVASCULARIZATION IN LEFT MAIN CORONARY ARTERY DISEASE WITH PROVEN ISCHEMIA: INSIGHTS FROM THE DEFINE-LM REGISTRY. Journal Of The American College Of Cardiology 2022, 79: 586. DOI: 10.1016/s0735-1097(22)01577-7.Peer-Reviewed Original Research
2020
Drug-Eluting Stents Versus Bypass Surgery for Left Main Disease: An Updated Meta-Analysis of Randomized Controlled Trials With Long-Term Follow-Up
Ahmad Y, Howard JP, Arnold AD, Ali ZA, Francis D, Moses JW, Leon MB, Kirtane AJ, Karmpaliotis D, Stone GW. Drug-Eluting Stents Versus Bypass Surgery for Left Main Disease: An Updated Meta-Analysis of Randomized Controlled Trials With Long-Term Follow-Up. The American Journal Of Cardiology 2020, 132: 168-172. PMID: 32718553, DOI: 10.1016/j.amjcard.2020.06.059.Peer-Reviewed Original ResearchResponse by Ahmad et al to Letter Regarding Article “Effects of Percutaneous Coronary Intervention on Death and Myocardial Infarction Stratified by Stable and Unstable Coronary Artery Disease: A Meta-Analysis of Randomized Controlled Trials”
Ahmad Y, Howard JP, Francis DP. Response by Ahmad et al to Letter Regarding Article “Effects of Percutaneous Coronary Intervention on Death and Myocardial Infarction Stratified by Stable and Unstable Coronary Artery Disease: A Meta-Analysis of Randomized Controlled Trials”. Circulation Cardiovascular Quality And Outcomes 2020, 13: e006862. PMID: 32482084, DOI: 10.1161/circoutcomes.120.006862.Peer-Reviewed Original ResearchClinical Pathway for Management of Suspected or Positive Novel Coronavirus-19 Patients With ST-Segment Elevation Myocardial Infarction.
Ranard LS, Ahmad Y, Masoumi A, Chuich T, Romney MS, Gavin N, Sayan OR, Kirtane AJ, Rabbani LE. Clinical Pathway for Management of Suspected or Positive Novel Coronavirus-19 Patients With ST-Segment Elevation Myocardial Infarction. Critical Pathways In Cardiology A Journal Of Evidence-Based Medicine 2020, 19: 49-54. PMID: 32356955, DOI: 10.1097/hpc.0000000000000223.Peer-Reviewed Original ResearchConceptsST-elevation myocardial infarctionMyocardial infarctionNewYork-Presbyterian/Columbia University Irving Medical CenterST-segment elevation myocardial infarctionManagement of STEMIColumbia University Irving Medical CenterStandard cardiac careElevation myocardial infarctionCOVID-19 patientsCoronavirus-19 patientsCoronavirus-19 diseaseOverwhelming healthcare systemsCOVID-19 diseaseFibrinolytic therapyCardiac careMultidisciplinary panelClinical pathwayMedical CenterSTEMI mimicsHealthcare systemInfarctionPatientsDiseaseGlobal pandemicMyopericarditisInter-observer differences in interpretation of coronary pressure-wire pullback data by non-expert interventional cardiologists
Warisawa T, Howard JP, Cook CM, Ahmad Y, Doi S, Nakayama M, Goto S, Yakuta Y, Karube K, Seike F, Uetani T, Murai T, Kikuta Y, Shiono Y, Kawase Y, Shun-Shin MJ, Kaihara T, Higuma T, Ishibashi Y, Matsuda H, Nishina H, Matsuo H, Escaned J, Akashi YJ, Davies JE. Inter-observer differences in interpretation of coronary pressure-wire pullback data by non-expert interventional cardiologists. Cardiovascular Intervention And Therapeutics 2020, 36: 289-297. PMID: 32430763, DOI: 10.1007/s12928-020-00673-3.Peer-Reviewed Original ResearchConceptsInterventional cardiologistsInter-observer differencesCoronary artery diseaseLow-volume centersHigh-volume centersExpert interventional cardiologistsExpertise of physiciansPhysiological patternsArtery diseaseRisk stratificationCenter volumeNon-expert doctorsPooled accuracyDisease patternsCardiologistsYears of experienceReference standardDiseaseDoctorsRevascularizationPatientsYearsPhysiciansPer-Vessel Level Analysis of Fractional Flow Reserve and Instantaneous Wave-Free Ratio Discordance ― Insights From the AJIP Registry ―
Warisawa T, Cook CM, Seligman H, Howard JP, Ahmad Y, Rajkumar C, Doi S, Nakayama M, Tanigaki T, Omori H, Nakajima A, Yamanaka F, Goto S, Yakuta Y, Karube K, Uetani T, Kikuta Y, Shiono Y, Kawase Y, Nishina H, Nakamura S, Escaned J, Akashi YJ, Matsuo H, Davies JE. Per-Vessel Level Analysis of Fractional Flow Reserve and Instantaneous Wave-Free Ratio Discordance ― Insights From the AJIP Registry ―. Circulation Journal 2020, 84: 1034-1038. PMID: 32321880, DOI: 10.1253/circj.cj-19-0785.Peer-Reviewed Original ResearchResponse by Ahmad et al to Letter Regarding Article, “Effects of Percutaneous Coronary Intervention on Death and Myocardial Infarction Stratified by Stable and Unstable Coronary Artery Disease: A Meta-Analysis of Randomized Controlled Trials”
Ahmad Y, Howard JP, Francis DP. Response by Ahmad et al to Letter Regarding Article, “Effects of Percutaneous Coronary Intervention on Death and Myocardial Infarction Stratified by Stable and Unstable Coronary Artery Disease: A Meta-Analysis of Randomized Controlled Trials”. Circulation Cardiovascular Quality And Outcomes 2020, 13: e006642. PMID: 32283970, DOI: 10.1161/circoutcomes.120.006642.Peer-Reviewed Original Research
2019
Physiological Pattern of Disease Assessed by Pressure-Wire Pullback Has an Influence on Fractional Flow Reserve/Instantaneous Wave-Free Ratio Discordance
Warisawa T, Cook CM, Howard JP, Ahmad Y, Doi S, Nakayama M, Goto S, Yakuta Y, Karube K, Shun-Shin MJ, Petraco R, Sen S, Nijjer S, Lamee R, Ishibashi Y, Matsuda H, Escaned J, di Mario C, Francis DP, Akashi YJ, Davies JE. Physiological Pattern of Disease Assessed by Pressure-Wire Pullback Has an Influence on Fractional Flow Reserve/Instantaneous Wave-Free Ratio Discordance. Circulation Cardiovascular Interventions 2019, 12: e007494-e007494. PMID: 31084237, PMCID: PMC6553990, DOI: 10.1161/circinterventions.118.007494.Peer-Reviewed Original ResearchConceptsInstantaneous wave-free ratioFractional flow reservePressure-wire pullbackCoronary artery diseaseArtery diseaseCoronary lesionsHemodynamic significancePhysiological patternsInternational multicenter registryIntermediate coronary lesionsMedian fractional flow reserveMulticenter registryFlow reserveDiseaseLesionsCut pointsIFR measurementDiscordanceRegistryFactors
2018
TCT-9 Coronary pressure and flow in patients with severe aortic stenosis and coronary artery disease undergoing TAVI: implications for clinical indices of coronary stenosis severity
Ahmad Y, Gotberg M, Cook C, Howard J, Malik I, Mikhail G, Francis D, Mayet J, Davies J, Sen S. TCT-9 Coronary pressure and flow in patients with severe aortic stenosis and coronary artery disease undergoing TAVI: implications for clinical indices of coronary stenosis severity. Journal Of The American College Of Cardiology 2018, 72: b4. DOI: 10.1016/j.jacc.2018.08.1085.Peer-Reviewed Original Research229Coronary haemodynamics in patients with severe aortic stenosis and coronary artery disease undergoing TAVI: implications for clinical indices of coronary stenosis severity
Ahmad Y, Gotberg M, Malik I, Mikhail G, Howard J, Demir O, Petraco R, Iglesias J, Francis D, Mayet J, Davies J, Sen S. 229Coronary haemodynamics in patients with severe aortic stenosis and coronary artery disease undergoing TAVI: implications for clinical indices of coronary stenosis severity. European Heart Journal 2018, 39: ehy564.229. DOI: 10.1093/eurheartj/ehy564.229.Peer-Reviewed Original ResearchAssessing coronary disease in patients with severe aortic stenosis: the need for a 'valid' gold standard for validation studies?
Sen S, Ahmad Y, Davies J. Assessing coronary disease in patients with severe aortic stenosis: the need for a 'valid' gold standard for validation studies? EuroIntervention 2018, 13: 1499-1502. PMID: 29345238, DOI: 10.4244/eijv13i13a240.Peer-Reviewed Original Research
2016
97 Multi-vessel Angioplasty at the Time of STEMI has Equivalent Mortality to a Culprit Only Strategy: Resolving The Paradox of Randomised Controlled Trials and Observational Studies in Multivessel Disease and STEMI
Ahmad Y, Cook C, Petraco R, Nijjer S, Al-Lamee R, Shun-Shin M, Keene D, Balu A, Malik I, Baker C, Mikhail G, Sethi A, Foale R, Davies J, Mayet J, Francis D, Sen S. 97 Multi-vessel Angioplasty at the Time of STEMI has Equivalent Mortality to a Culprit Only Strategy: Resolving The Paradox of Randomised Controlled Trials and Observational Studies in Multivessel Disease and STEMI. Heart 2016, 102: a68. DOI: 10.1136/heartjnl-2016-309890.97.Peer-Reviewed Original ResearchHigh-risk patientsLarge observational studiesObservational studyResidual diseaseEquivalent mortalityPrimary percutaneous coronary interventionST-elevation myocardial infarctionMulti-vessel diseasePercutaneous coronary interventionRandomised Controlled TrialsAllocation biasMultivessel diseaseCoronary interventionRisk patientsControlled TrialsMyocardial infarctionSmall RCTsPatientsHigh mortalitySTEMIMortalityDiseaseConflicting resultsRCTsPPCI