2022
Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis.
Kelshiker MA, Seligman H, Howard JP, Rahman H, Foley M, Nowbar AN, Rajkumar CA, Shun-Shin MJ, Ahmad Y, Sen S, Al-Lamee R, Petraco R. Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis. European Heart Journal 2022, 43: 1582-1593. PMID: 36282780, DOI: 10.1093/eurheartj/ehab775.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsAbnormal coronary flow reserveCoronary flow reserveCause mortalityCoronary flowHigh incidenceHazard ratioFlow reserveAdverse cardiovascular eventsCoronary microvascular dysfunctionAcute coronary syndromeRandom-effects modelEstimate of effectCardiovascular eventsCardiovascular outcomesCoronary syndromeMicrovascular dysfunctionHeart failureHeart transplantClinical outcomesPatient groupRisk modificationHigh riskClinical practiceSystematic review
2021
Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis
Kelshiker MA, Seligman H, Howard JP, Rahman H, Foley M, Nowbar AN, Rajkumar CA, Shun-Shin MJ, Ahmad Y, Sen S, Al-Lamee R, Petraco R, Cole G, Hoole S, Paul D, Rigo F, Francis D, Mayet J. Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis. European Heart Journal 2021, 43: 1582-1593. PMID: 34849697, PMCID: PMC9020988, DOI: 10.1093/eurheartj/ehab775.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsAbnormal coronary flow reserveCoronary flow reserveCause mortalityCoronary flowHigh incidenceHazard ratioFlow reserveAdverse cardiovascular eventsCoronary microvascular dysfunctionAcute coronary syndromeRandom-effects modelEstimate of effectCardiovascular eventsCardiovascular outcomesCoronary syndromeMicrovascular dysfunctionHeart failureHeart transplantClinical outcomesPatient groupRisk modificationHigh riskClinical practiceSystematic review
2020
Long‐Term Effects of Transcatheter Aortic Valve Implantation on Coronary Hemodynamics in Patients With Concomitant Coronary Artery Disease and Severe Aortic Stenosis
Vendrik J, Ahmad Y, Eftekhari A, Howard JP, Wijntjens GWM, Stegehuis VE, Cook C, Terkelsen CJ, Christiansen EH, Koch KT, Piek JJ, Sen S, Baan J. Long‐Term Effects of Transcatheter Aortic Valve Implantation on Coronary Hemodynamics in Patients With Concomitant Coronary Artery Disease and Severe Aortic Stenosis. Journal Of The American Heart Association 2020, 9: e015133. PMID: 32102615, PMCID: PMC7335578, DOI: 10.1161/jaha.119.015133.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationSevere aortic stenosisConcomitant coronary artery diseaseAortic stenosisAortic valve implantationCoronary artery diseasePost-TAVICoronary flowArtery diseaseValve implantationCoronary hemodynamicsLarge-scale prospective randomized trialsFractional flow reserve assessmentProspective randomized trialsLow-risk patientsHyperemic coronary flowInstantaneous wave-free ratioFractional flow reserveCoronary stenosis severityYounger patientsCoronary lesionsRandomized trialsDiastolic flowPatient populationWave-free period
2018
Coronary Hemodynamics in Patients With Severe Aortic Stenosis and Coronary Artery Disease Undergoing Transcatheter Aortic Valve Replacement Implications for Clinical Indices of Coronary Stenosis Severity
Ahmad Y, Götberg M, Cook C, Howard JP, Malik I, Mikhail G, Frame A, Petraco R, Rajkumar C, Demir O, Iglesias JF, Bhindi R, Koul S, Hadjiloizou N, Gerber R, Ramrakha P, Ruparelia N, Sutaria N, Kanaganayagam G, Ariff B, Fertleman M, Anderson J, Chukwuemeka A, Francis D, Mayet J, Serruys P, Davies J, Sen S. Coronary Hemodynamics in Patients With Severe Aortic Stenosis and Coronary Artery Disease Undergoing Transcatheter Aortic Valve Replacement Implications for Clinical Indices of Coronary Stenosis Severity. JACC Cardiovascular Interventions 2018, 11: 2019-2031. PMID: 30154062, PMCID: PMC6197079, DOI: 10.1016/j.jcin.2018.07.019.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic Valve StenosisBlood Flow VelocityCardiac CatheterizationCoronary Artery DiseaseCoronary StenosisFemaleFractional Flow Reserve, MyocardialHemodynamicsHumansHyperemiaLondonMalePredictive Value of TestsReproducibility of ResultsSeverity of Illness IndexSwedenTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsSevere aortic stenosisTranscatheter aortic valve replacementCoronary artery diseaseCoronary stenosis severityAortic stenosisHyperemic coronary flowFractional flow reserveArtery diseaseCoronary flowStenosis severityWave-free periodClinical indicesHyperemic flowFlow reserveInstantaneous wave-free ratio valueIntracoronary pressureConcomitant coronary artery diseaseAortic valve replacementStenotic aortic valvesInstantaneous wave-free ratioPhasic coronary flowValve replacementHyperemic indexAortic valveCoronary pressure