2024
Physiological Assessment with iFR prior to FFR Measurement in Left Main Disease
Warisawa T, Cook C, Ahmad Y, Howard J, Seligman H, Rajkumar C, Toya T, Doi S, Nakajima A, Nakayama M, Vera-Urquiza R, Yuasa S, Sato T, Kikuta Y, Kawase Y, Nishina H, Al-Lamee R, Sen S, Lerman A, Matsuo H, Akashi Y, Escaned J, Davies J. Physiological Assessment with iFR prior to FFR Measurement in Left Main Disease. Cardiovascular Intervention And Therapeutics 2024, 39: 241-251. PMID: 38642290, PMCID: PMC11164744, DOI: 10.1007/s12928-024-00989-4.Peer-Reviewed Original ResearchMajor adverse cardiovascular eventsArea under the curveFractional flow reserveLeft main diseaseOptimal cut-off valueInstantaneous wave-free ratioAdverse cardiovascular eventsClinical outcomesCardiovascular eventsRevascularization decision-makingFlow reserveMain diseaseClinical outcomes of patientsPhysiological assessmentPrediction of MACEPrediction of adverse cardiovascular eventsFractional flow reserve measurementsInternational multicenter registryReceiver-operating characteristic analysisOutcomes of patientsLeft main coronary artery diseasePrediction of cardiovascular eventsComposite of deathNon-fatal myocardial infarctionIschemia-driven target lesion revascularization
2022
Meta-Analysis of Provisional Versus Systematic Double-Stenting Strategy for Left Main Bifurcation Lesions
Abdelfattah OM, Radwan A, Sayed A, Elbadawi A, Derbas LA, Saleh Y, Ahmad Y, ElJack A, Masoumi A, Karmpaliotis D, Elgendy IY, Alfonso F. Meta-Analysis of Provisional Versus Systematic Double-Stenting Strategy for Left Main Bifurcation Lesions. Cardiovascular Revascularization Medicine 2022, 45: 53-62. PMID: 35934644, DOI: 10.1016/j.carrev.2022.07.017.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsTarget lesion revascularizationPercutaneous coronary interventionBifurcation percutaneous coronary interventionSecond generation drug eluting stentsDrug eluting stentsDouble-stent strategyMyocardial infarctionObservational studyLesion revascularizationCause mortalityCardiovascular mortalityDouble stentingStent thrombosisProvisional stentingLower major adverse cardiovascular eventsInternational Clinical Trials Registry PlatformClinical Trials Registry PlatformMain bifurcation lesionsAdverse cardiovascular eventsCochrane Central RegisterTrials Registry PlatformSignificant lower rateProvisional stenting strategyCardiovascular eventsCoronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis.
Kelshiker MA, Seligman H, Howard JP, Rahman H, Foley M, Nowbar AN, Rajkumar CA, Shun-Shin MJ, Ahmad Y, Sen S, Al-Lamee R, Petraco R. Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis. European Heart Journal 2022, 43: 1582-1593. PMID: 36282780, DOI: 10.1093/eurheartj/ehab775.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsAbnormal coronary flow reserveCoronary flow reserveCause mortalityCoronary flowHigh incidenceHazard ratioFlow reserveAdverse cardiovascular eventsCoronary microvascular dysfunctionAcute coronary syndromeRandom-effects modelEstimate of effectCardiovascular eventsCardiovascular outcomesCoronary syndromeMicrovascular dysfunctionHeart failureHeart transplantClinical outcomesPatient groupRisk modificationHigh riskClinical practiceSystematic review
2021
Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis
Kelshiker MA, Seligman H, Howard JP, Rahman H, Foley M, Nowbar AN, Rajkumar CA, Shun-Shin MJ, Ahmad Y, Sen S, Al-Lamee R, Petraco R, Cole G, Hoole S, Paul D, Rigo F, Francis D, Mayet J. Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis. European Heart Journal 2021, 43: 1582-1593. PMID: 34849697, PMCID: PMC9020988, DOI: 10.1093/eurheartj/ehab775.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsAbnormal coronary flow reserveCoronary flow reserveCause mortalityCoronary flowHigh incidenceHazard ratioFlow reserveAdverse cardiovascular eventsCoronary microvascular dysfunctionAcute coronary syndromeRandom-effects modelEstimate of effectCardiovascular eventsCardiovascular outcomesCoronary syndromeMicrovascular dysfunctionHeart failureHeart transplantClinical outcomesPatient groupRisk modificationHigh riskClinical practiceSystematic review
2014
Antiplatelet Therapy for Patients with Peripheral Arterial Disease
Myat A, Ahmad Y, Redwood S. Antiplatelet Therapy for Patients with Peripheral Arterial Disease. 2014, 245-252. DOI: 10.1002/9781118493984.ch29.Peer-Reviewed Original ResearchLower extremity artery diseasePeripheral artery diseaseAntiplatelet therapyArtery diseaseMyocardial infarctionSymptomatic lower extremity artery diseasePrevalence of PADClass IA recommendationAdverse cardiovascular eventsNonfatal myocardial infarctionPeripheral arterial diseaseNonfatal strokePharmacotherapeutic armamentariumVascular deathCardiovascular eventsAntiplatelet agentsRevascularization proceduresAntiplatelet managementArterial diseaseCerebrovascular diseaseCoronary arteryCoronary circulationVessel patencyVascular bedIA recommendation