Recent advances in understanding inherited disorders of keratinization
Zaki T, Choate K. Recent advances in understanding inherited disorders of keratinization. F1000Research 2018, 7: f1000 faculty rev-919. PMID: 30002814, PMCID: PMC6024232, DOI: 10.12688/f1000research.14514.1.Peer-Reviewed Original ResearchCorneocyte lipid envelopeNovel genesNext-generation sequencingEpidermal lipid barrierHuman geneticsCeramide pathwayIntercellular lipid layersLipid envelopeLipid synthesisBarrier functionSeries of discoveriesCompensatory hyperproliferationMutationsNovel mutationsLipid componentsLipid barrierWater lossRecent advancesPalmoplantar keratodermaAbnormal barrier functionGenesGeneticsNew findingsSequencingCeramide