2003
Hypothalamic hamartomas: seven cases and review of the literature
Nguyen D, Singh S, Zaatreh M, Novotny E, Levy S, Testa F, Spencer SS. Hypothalamic hamartomas: seven cases and review of the literature. Epilepsy & Behavior 2003, 4: 246-258. PMID: 12791326, DOI: 10.1016/s1525-5050(03)00086-6.Peer-Reviewed Original ResearchConceptsSessile lesionsPrecocious pubertyDifferent surgical optionsGamma Knife surgeryRare developmental lesionIntrinsic epileptogenicityGelastic seizuresGelastic epilepsySeizure typesPartial resectionSurgical optionsHypothalamic hamartomaOpen surgeryTranscallosal approachClinical aspectsSubtemporal approachIntraventricular componentDevelopmental lesionsCognitive declineLesionsAvailable evidenceResectionSurgerySeizuresSubsequent development
2001
Two‐Year Remission and Subsequent Relapse in Children with Newly Diagnosed Epilepsy
Berg A, Shinnar S, Levy S, Testa F, Smith‐Rapaport S, Beckerman B, Ebrahimi N. Two‐Year Remission and Subsequent Relapse in Children with Newly Diagnosed Epilepsy. Epilepsia 2001, 42: 1553-1562. PMID: 11879366, DOI: 10.1046/j.1528-1157.2001.21101.x.Peer-Reviewed Original ResearchConceptsEpilepsy syndromesSymptomatic etiologySeizure frequencyMultivariable analysisInitial EEGFamily historyCox proportional hazards modelInitial seizure frequencyRemote symptomatic etiologyTwo-year remissionRecurrence of seizuresPredictors of remissionIdiopathic generalized epilepsyYounger onset ageProportional hazards modelJuvenile myoclonic epilepsyBenign rolandic epilepsySeizure outcomeRemission rateSeizure controlSeizure typesFocal slowingGeneralized epilepsySubsequent relapseEEG slowing
1999
Treatment of Newly Diagnosed Pediatric Epilepsy: A Community-Based Study
Berg A, Levy S, Testa F, Shinnar S. Treatment of Newly Diagnosed Pediatric Epilepsy: A Community-Based Study. JAMA Pediatrics 1999, 153: 1267-1271. PMID: 10591304, DOI: 10.1001/archpedi.153.12.1267.Peer-Reviewed Original ResearchConceptsAntiepileptic drugsPediatric epilepsyInitial diagnosisIdiopathic localization-related epilepsyFirst antiepileptic drugTime of diagnosisTreatment of NewlyInitiation of treatmentLocalization-related epilepsySpecific seizure typesCommunity-based studyForms of epilepsyFrequency of treatmentDiagnosis of epilepsyFirst seizureSeizure typesUnprovoked seizuresSodium valproateSpecific medicationsCurrent guidelinesFirst drugInvestigational drugsEpilepsyMonths 90Specific drugs