Pengfei Guo, MBBS, PhD
Postdoctoral AssociateAbout
Research
Publications
2024
Potentially inappropriate prescribing among older adults with hypertension in China: prevalence and related comorbidities across different outpatient settings
Chen J, Wang S, Lu L, Yang Y, Wang K, Zheng J, Zhou Z, Guo P, Cai Y, Zhang Q. Potentially inappropriate prescribing among older adults with hypertension in China: prevalence and related comorbidities across different outpatient settings. Frontiers In Pharmacology 2024, 15: 1439230. DOI: 10.3389/fphar.2024.1439230.Peer-Reviewed Original ResearchCommunity health centersPrevalence of PIPOlder adult outpatientsOlder adultsModified Poisson regression analysisOccurrence of PIPAssociated with chronic gastrointestinal diseasesAdult outpatientsProton pump inhibitorsAssociated with PIPPoisson regression analysisElectronic medical recordsCross-sectional studyPrimary medical institutionsChronic gastrointestinal diseasesPharmacy integrationHealth centersHealthcare settingsBeers CriteriaSample sizeHospital settingBehavioral disordersOutpatient prescriptionsOutpatient settingVulnerable populationsAssociation Between Particulate Matter Exposure and Preterm Birth in Women With Abnormal Preconception Thyrotropin Levels: Large Cohort Study
Xu T, Ni H, Cai X, Dai T, Wang L, Xiao L, Zeng Q, Yu X, Han L, Guo P. Association Between Particulate Matter Exposure and Preterm Birth in Women With Abnormal Preconception Thyrotropin Levels: Large Cohort Study. JMIR Public Health And Surveillance 2024, 10: e53879. PMID: 39114947, PMCID: PMC11310741, DOI: 10.2196/53879.Peer-Reviewed Original ResearchConceptsPreconception TSH levelsSusceptible exposure windowsRisk of preterm birthPM2.5 exposureCox proportional hazards modelsProportional hazards modelNational Free Pre-Pregnancy Checkups ProjectPreterm birthExposure windowsCohort studyHighest PTB riskHazards modelElevated risk of preterm birthEarly PTBExposure to particulate matterImpact of PM2.5 exposureParticulate matter exposurePTB riskGestational weeksLate preterm birthElevated riskPreconception thyroid-stimulating hormonePregnant womenWomenTSH levelsImpact of Ambient Temperature on Mortality Burden and Spatial Heterogeneity in 16 Prefecture-Level Cities of a Low-Latitude Plateau Area in Yunnan Province: Time-Series Study
Chen Y, Zhou L, Zha Y, Wang Y, Wang K, Lu L, Guo P, Zhang Q. Impact of Ambient Temperature on Mortality Burden and Spatial Heterogeneity in 16 Prefecture-Level Cities of a Low-Latitude Plateau Area in Yunnan Province: Time-Series Study. JMIR Public Health And Surveillance 2024, 10: e51883. PMID: 39045874, PMCID: PMC11287102, DOI: 10.2196/51883.Peer-Reviewed Original ResearchConceptsPrefecture-level citiesYunnan ProvinceSpatial heterogeneityMean temperatureMortality burdenNonaccidental deathsLow latitudesMeteorological dataHealth policy formulationPeople aged <Health-resource factorsPlateau areaCardiovascular diseaseYears of lifePublic health issueTime-series studyEstimates of effectClimate changeTime seriesYunnanNonaccidental mortalityProportion of heterogeneityPlateau regionYLLMultivariate meta-analysisAssociation between Personal Abiotic Airborne Exposures and Body Composition Changes among Healthy Adults (60–69 Years Old): A Combined Exposome-Wide and Lipidome Mediation Approach from the China BAPE Study
Sun P, Guo X, Ding E, Li C, Ren H, Xu Y, Qian J, Deng F, Shi W, Dong H, Lin E, Guo P, Fang J, Zhang Q, Zhao W, Tong S, Lu X, Pollitt K, Shi X, Tang S. Association between Personal Abiotic Airborne Exposures and Body Composition Changes among Healthy Adults (60–69 Years Old): A Combined Exposome-Wide and Lipidome Mediation Approach from the China BAPE Study. Environmental Health Perspectives 2024, 132: 077005. PMID: 39028628, PMCID: PMC11259245, DOI: 10.1289/ehp13865.Peer-Reviewed Original ResearchConceptsFat mass indicatorsHealthy older adultsBayesian kernel machine regressionVisceral fat areaOlder adultsPercent body fatBody compositionBody fat massExposome-wide association studyPrevention of chronic diseasesAir pollution exposureBody composition indicatorsMediation analysisInBody 770 deviceHealthy adultsAssociated with increased body fat massBody composition changesKernel machine regressionBayesian kernel machine regression modelsChronic diseasesPollution exposureBody fatAssociation studiesAdverse health effectsFat areaPersonal exposure to airborne organic pollutants and lung function changes among healthy older adults
Guo X, Ren H, Sun P, Ding E, Fang J, Fang K, Ma X, Li C, Li C, Xu Y, Cao K, Lin E, Guo P, Pollitt K, Tong S, Tang S, Shi X. Personal exposure to airborne organic pollutants and lung function changes among healthy older adults. Environmental Research 2024, 258: 119411. PMID: 38876423, DOI: 10.1016/j.envres.2024.119411.Peer-Reviewed Original Research
2023
Per- and polyfluoroalkyl substances and sleep health in U.S. adults, NHANES 2005–2014
Guo P, Jin Z, Bellia G, Luo J, Inoue K, Pollitt K, Deziel N, Liew Z. Per- and polyfluoroalkyl substances and sleep health in U.S. adults, NHANES 2005–2014. Environmental Research 2023, 237: 117092. PMID: 37683785, DOI: 10.1016/j.envres.2023.117092.Peer-Reviewed Original ResearchSleep disordersSleep outcomesU.S. adultsNHANES 2005Inverse associationSleep durationSerum polyfluoroalkyl substancesCentral nervous systemSerum concentration dataDaily sleep durationExposure tertilesOxidative inflammatory responseQuartile increaseBias analysisInflammatory responseExcessive sleepUncontrolled confoundingNervous systemSleep healthPFAS exposureHealth measuresQuantitative bias analysisLogistic regressionConsistent associationDisordersPersistence of severe global inequalities in the burden of blindness and vision loss from 1990 to 2019: findings from the Global Burden of Disease Study 2019
Li Y, Wang H, Guan Z, Guo C, Guo P, Du Y, Yin S, Chen B, Jiang J, Ma Y, Jing L, Huang Y, Zheng K, Ma Q, Zhou R, Chen M, Congdon N, Qiu K, Zhang M. Persistence of severe global inequalities in the burden of blindness and vision loss from 1990 to 2019: findings from the Global Burden of Disease Study 2019. British Journal Of Ophthalmology 2023, 108: 301-309. PMID: 37423644, DOI: 10.1136/bjo-2022-321801.Peer-Reviewed Original ResearchConceptsSlope index of inequalitySocio-demographic indexDisability-adjusted life yearsBurden of blindnessGlobal burdenHealth inequalitiesAge-standardised DALY ratesGlobal Burden of Disease StudyLow-middle Socio-demographic IndexBurden of Disease StudyGlobal Burden of DiseaseElimination of avoidable blindnessIndex of inequalityLow socio-demographic indexRisk Factors StudyConcentration indexMiddle-income countriesBurden of diseaseDALY ratesVision lossDecreased burdenSlope indexAvoidable blindnessLow-incomeSecondary analysis
2022
Human health effects of chemical mixtures
Liew Z, Guo P. Human health effects of chemical mixtures. Science 2022, 375: 720-721. PMID: 35175805, PMCID: PMC9805352, DOI: 10.1126/science.abn9080.Commentaries, Editorials and Letters
2021
Adherence to Traditional Chinese Postpartum Practices and Postpartum Depression: A Cross-Sectional Study in Hunan, China
Guo P, Xu D, Liew Z, He H, Brocklehurst P, Taylor B, Zhang C, Jin X, Gong W. Adherence to Traditional Chinese Postpartum Practices and Postpartum Depression: A Cross-Sectional Study in Hunan, China. Frontiers In Psychiatry 2021, 12: 649972. PMID: 34385937, PMCID: PMC8353075, DOI: 10.3389/fpsyt.2021.649972.Peer-Reviewed Original ResearchExploring personal chemical exposures in China with wearable air pollutant monitors: A repeated-measure study in healthy older adults in Jinan, China
Guo P, Lin EZ, Koelmel JP, Ding E, Gao Y, Deng F, Dong H, Liu Y, Cha Y, Fang J, Shi X, Tang S, Godri Pollitt KJ. Exploring personal chemical exposures in China with wearable air pollutant monitors: A repeated-measure study in healthy older adults in Jinan, China. Environment International 2021, 156: 106709. PMID: 34153889, DOI: 10.1016/j.envint.2021.106709.Peer-Reviewed Original ResearchConceptsVolatile organic compoundsPolycyclic aromatic hydrocarbonsAirborne chemical contaminantsPersonal exposure profilesPassive air samplersOrganic compoundsPassive samplersChemical classesChemical contaminantsChemical analysisPersonal chemical exposureCertain polycyclic aromatic hydrocarbonsChemical exposureAirborne compoundsAirborne contaminantsCompoundsAromatic hydrocarbonsContaminantsAir monitoring sitesComprehensive characterizationPhthalateNitroaromaticsRepeated-measures studyAir samplerNitrobenzene