2024
Efficient standardization of clinical T2‐weighted images: Phase‐conjugacy e‐CAMP with projected gradient descent
Zhang H, Elsaid N, Sun H, Tagare H, Galiana G. Efficient standardization of clinical T2‐weighted images: Phase‐conjugacy e‐CAMP with projected gradient descent. Magnetic Resonance In Medicine 2024 PMID: 38988054, DOI: 10.1002/mrm.30214.Peer-Reviewed Original ResearchData fidelity termSignal evolution modelFidelity termGradient descentProjected GradientEfficient algorithmVirtual conjugate coilAlgorithmObjective functionMapping errorsTunable parametersLinear constraintsSampling schemeTSE dataLong echo train lengthMapsTrain lengthVirtualTurbo spin echoEcho train lengthHigh-resolutionSchemeDataBackground phaseError rangeConstrained alternating minimization for parameter mapping (CAMP)
Elsaid N, Dispenza N, Hu C, Peters D, Constable R, Tagare H, Galiana G. Constrained alternating minimization for parameter mapping (CAMP). Magnetic Resonance Imaging 2024, 110: 176-183. PMID: 38657714, PMCID: PMC11193090, DOI: 10.1016/j.mri.2024.04.029.Peer-Reviewed Original ResearchConceptsAlternating minimizationAccelerated parameter mappingImage qualityReconstructed image qualityEfficient reconstruction algorithmSacrificing model accuracyParameter mapsPhantom studyK-space samplingAcceleration datasetsK-spaceUndersampling artifactsCartesian acquisitionConsecutive imagesReconstruction algorithmIndividual imagesModel cost functionExponential decayEcho timeReconstruction methodCost functionReduce artifactsPhantomScan timeObjective functionClinical physiology: the crucial role of MRI in evaluation of peripheral artery disease
Elsaid N, Peters D, Galiana G, Sinusas A. Clinical physiology: the crucial role of MRI in evaluation of peripheral artery disease. AJP Heart And Circulatory Physiology 2024, 326: h1304-h1323. PMID: 38517227, DOI: 10.1152/ajpheart.00533.2023.Peer-Reviewed Original ResearchPeripheral arterial diseaseMagnetic resonance imagingArtery diseaseClinical applicationEvaluation of peripheral arterial diseaseTranslation to clinical researchPre-clinical modelsMedial vascular calcificationDiagnosis of peripheral arterial diseaseExcellent soft tissue contrastPathophysiology of peripheral arterial diseaseAssessment of peripheral arterial diseaseNoninvasive imaging toolMR imaging technologyMR imaging techniquesSoft tissue contrastMultiplanar imaging capabilityAutonomic dysfunctionMicrovascular dysfunctionRisk stratificationPeripheral neuropathyComprehensive physiological assessmentTreatment outcomesVascular calcificationTherapy planning
2023
3D FRONSAC with PSF reconstruction
Rodriguez Y, Elsaid N, Keil B, Galiana G. 3D FRONSAC with PSF reconstruction. Journal Of Magnetic Resonance 2023, 355: 107544. PMID: 37672990, PMCID: PMC10592039, DOI: 10.1016/j.jmr.2023.107544.Peer-Reviewed Original ResearchA Physics-Based Algorithm to Universally Standardize Routinely Obtained Clinical T2-Weighted Images
Elsaid N, Tagare H, Galiana G. A Physics-Based Algorithm to Universally Standardize Routinely Obtained Clinical T2-Weighted Images. Academic Radiology 2023, 31: 582-595. PMID: 37407374, PMCID: PMC10761595, DOI: 10.1016/j.acra.2023.05.036.Peer-Reviewed Original ResearchSingle image dataMachine learningPhysics-based constraintsImage dataClassical optimization methodsRaw datasetBrain imagesStandardized datasetClinical imagesReconstruction methodSlow adoptionImagesParameter mappingOptimization methodDatasetLarge-scale analysisW imagesMR imagesW scansHardwareAcquisition parametersConstraintsAlgorithmInitializationProtocol
2022
Validation of Muscle Fiber Architecture of the Human Tongue Revealed by Diffusion Magnetic Resonance Imaging With Histology Verification.
Liang X, Elsaid NMH, Jiang L, Roys S, Puche AC, Gullapalli RP, Stone M, Prince JL, Zhuo J. Validation of Muscle Fiber Architecture of the Human Tongue Revealed by Diffusion Magnetic Resonance Imaging With Histology Verification. Journal Of Speech Language And Hearing Research 2022, 65: 3661-3673. PMID: 36054846, PMCID: PMC9927595, DOI: 10.1044/2022_jslhr-22-00040.Peer-Reviewed Original ResearchConceptsDiffusion-weighted magnetic resonance imagingMuscle architectureMagnetic resonance imagingComplex muscle architectureHuman tongueOral surgeryHealthy volunteersEosin stainingDiffusion magnetic resonanceResonance imagingMuscle fibersEntire tongueMuscle fiber architectureHistologyMuscle fiber orientationTongueMagnetic resonanceTensor imagesSurgeryTractogramsSwallowingHeadHematoxylinStructural connectivity mapping in human hippocampal-subfields using super-resolution hybrid diffusion imaging: a feasibility study
Elsaid NMH, Coupé P, Saykin AJ, Wu YC. Structural connectivity mapping in human hippocampal-subfields using super-resolution hybrid diffusion imaging: a feasibility study. Neuroradiology 2022, 64: 1989-2000. PMID: 35556149, PMCID: PMC9474597, DOI: 10.1007/s00234-022-02968-z.Peer-Reviewed Original ResearchConceptsDisease Research CenterHippocampal subfieldsAlzheimer's Disease Research CenterHippocampal subfield analysisStructural connectivityYoung healthy participantsCerebral cortexHippocampal areaWhole hippocampusConclusionThe findingsSubfield analysisHealthy participantsYoung adultsPurposeThe goalConnectivity mappingFuture studiesCurrent studyTractography streamlinesDiffusion imagesHippocampusDementiaFeasibility studyCortexStudyMRIg-CAMP reconstructs multiple b-value diffusion weighted images from a single RESOLVE k-space
Elsaid N, Tagare H, Galiana G. g-CAMP reconstructs multiple b-value diffusion weighted images from a single RESOLVE k-space. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2022 DOI: 10.58530/2022/2344.Peer-Reviewed Original Research
2021
Prospective motion detection and re‐acquisition in diffusion MRI using a phase image–based method—Application to brain and tongue imaging
Liang X, Su P, Patil SG, Elsaid NMH, Roys S, Stone M, Gullapalli RP, Prince JL, Zhuo J. Prospective motion detection and re‐acquisition in diffusion MRI using a phase image–based method—Application to brain and tongue imaging. Magnetic Resonance In Medicine 2021, 86: 725-737. PMID: 33665929, PMCID: PMC9169515, DOI: 10.1002/mrm.28729.Peer-Reviewed Original ResearchConceptsMotion detectionProspective motion correction techniqueMotion-corrupted imagesMotion detection methodMotion-corrupted dataAcquisition frameworkMotion correction techniqueVisual inspectionDMRI acquisitionsDiffusion estimationNonrigid motionTongue imagingImage qualityAcquisition techniquesTractography resultsDMRIDiffusion MRIInspectionMotion artifactsTechniqueDetectionImagesFrameworkArtifacts
2020
Resting state functional MRI in infants with prenatal opioid exposure—a pilot study
Radhakrishnan R, Elsaid NMH, Sadhasivam S, Reher TA, Hines AC, Yoder KK, Saykin AJ, Wu YC. Resting state functional MRI in infants with prenatal opioid exposure—a pilot study. Neuroradiology 2020, 63: 585-591. PMID: 32978671, PMCID: PMC9162800, DOI: 10.1007/s00234-020-02552-3.Peer-Reviewed Original ResearchConceptsPrenatal opioid exposureOpioid exposureState functional MRIFunctional connectivityFunctional MRISeed-based functional connectivity analysisPilot studyAmygdalar functional connectivityMaternal opioid exposureUtero opioid exposureAmygdala functional connectivityFuture larger studiesPrenatal drug exposureAmygdala seed regionMedial prefrontal cortexFunctional connectivity analysisPrenatal opioidsGestational agePrenatal exposureDrug exposureInfant sexMaternal depressionProspective IRBConclusionThis findingNaïve infantsLongitudinal white-matter abnormalities in sports-related concussion: A diffusion MRI study
Wu YC, Harezlak J, Elsaid NMH, Lin Z, Wen Q, Mustafi SM, Riggen LD, Koch KM, Nencka AS, Meier TB, Mayer AR, Wang Y, Giza CC, DiFiori JP, Guskiewicz KM, Mihalik JP, LaConte SM, Duma SM, Broglio SP, Saykin AJ, McCrea MA, McAllister TW. Longitudinal white-matter abnormalities in sports-related concussion: A diffusion MRI study. Neurology 2020, 95: 10.1212/wnl.0000000000009930. PMID: 32641518, PMCID: PMC7605507, DOI: 10.1212/wnl.0000000000009930.Peer-Reviewed Original ResearchConceptsSport-related concussionWhite matter abnormalitiesDiffusion tensor imagingWhite matterDTI metricsOutcome measuresCollegiate athletesMean diffusivityContact sport exposureTime pointsClinical outcome measuresGroup differencesProportional hazards modelWhite matter areasAffected white matterAcute concussionAsymptomatic stateClinical outcomesPersistent abnormalitiesClinical assessmentCorpus callosumConcussion assessmentDiffusion MRI studyHazards modelRecovery time
2019
Phase Image Texture Analysis for Motion Detection in Diffusion MRI (PITA-MDD)
Elsaid NMH, Prince JL, Roys S, Gullapalli RP, Zhuo J. Phase Image Texture Analysis for Motion Detection in Diffusion MRI (PITA-MDD). Magnetic Resonance Imaging 2019, 62: 228-241. PMID: 31319127, PMCID: PMC6697150, DOI: 10.1016/j.mri.2019.07.009.Peer-Reviewed Original ResearchConceptsImage texture analysisMotion detectionAutomatic motion detectionTexture analysisSubject motionReal-time feedbackData corruptionMotion correction methodData quality controlEfficient mannerMotion corruptionMultiple applicationsMotion metricsProspective motion correctionPhase imagesMotion correctionImagesMagnitude imagesPhase artifactsMetricsFast alternativeNovel methodDMRI methodsDiffusion MRICorrection methodSuper-Resolution Diffusion Tensor Imaging using SRCNN: A Feasibility Study*
Elsaid NMH, Wu YC. Super-Resolution Diffusion Tensor Imaging using SRCNN: A Feasibility Study*. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2019, 00: 2830-2834. PMID: 31946482, PMCID: PMC7219542, DOI: 10.1109/embc.2019.8857125.Peer-Reviewed Original Research
2018
Laplace-based modeling of fiber orientation in the tongue
Gomez AD, Elsaid N, Stone ML, Zhuo J, Prince JL. Laplace-based modeling of fiber orientation in the tongue. Biomechanics And Modeling In Mechanobiology 2018, 17: 1119-1130. PMID: 29675685, PMCID: PMC6050131, DOI: 10.1007/s10237-018-1018-7.Peer-Reviewed Original ResearchConceptsFiber distributionFiber orientationFiber distribution modelDisplacement trackingInternal jointsSurface displacementsMechanical modelingTissue motionBiomechanical simulationSimulation purposesModel-based reconstructionMechanical simulationsFiber modelKinematic responseFiber directionalityExperimental observationsSimulationsLaplace equationResidual magnitudeGreat influenceDiffusion resultsGood overall agreementModelingAverage discrepancyFibers
2016
The Impact of Anisotropy on the Accuracy of Conductivity Imaging: A Quantitative Validation Study
Elsaid NM, Nachman AI, Ma W, DeMonte TP, Joy ML. The Impact of Anisotropy on the Accuracy of Conductivity Imaging: A Quantitative Validation Study. IEEE Transactions On Medical Imaging 2016, 36: 507-517. PMID: 28113393, DOI: 10.1109/tmi.2016.2617873.Peer-Reviewed Original ResearchConceptsCurrent density imagingConductivity imaging methodFinite element modelConductivity reconstruction methodAnisotropic brain tissueElement modelConductivity methodConductivity imagingImpact of anisotropyTissue anisotropyIsotropic conductivityValidation resultsImaging methodQuantitative validation studyReconstruction methodDensity imagingSuperior accuracyAnisotropy yieldsAccuracyConductivityAnisotropyMethodSimulations
2013
Experimental Implementation of a New Method of Imaging Anisotropic Electric Conductivities
Ma W, DeMonte TP, Nachman AI, Elsaid NM, Joy ML. Experimental Implementation of a New Method of Imaging Anisotropic Electric Conductivities. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2013, 2013: 6437-6440. PMID: 24111215, DOI: 10.1109/embc.2013.6611028.Peer-Reviewed Original ResearchConceptsCurrent Density Impedance ImagingExperimental implementationAnisotropic electric conductivityImpedance imagingElectric conductivityTissue phantomsAnisotropic conductivityConductivity tensorNew methodExperimental dataTissue propertiesConductivityNovel imaging approachAnisotropic impedanceNovel techniqueImaging approachEffective wayBiological media