Michael Hines, PhD

My interest is in the area of conceptual control of neural modeling. NEURON, a program we have developed and provide freely for Mac OS X, MS Windows, and UNIX, simplifies the creation and analysis of neural model for nonspecialists in numerical methods and programming. It is used by neuroscientists around the world to investigate cellular and network mechanisms that are involved in inborn and acquired disorders such as epilepsy, multiple sclerosis, and disorders of learning and memory, and how they are affected by therapeutic interventions such as medications and deep brain stimulation. With NEURON, investigators can simulate individual cells and networks of neurons on workstations, clusters, and massively parallel supercomputers. Model properties may include, but are not limited to, complex branching morphology, multiple channel types, inhomogeneous channel distribution, ionic diffusion, extracellular fields, electronic instrumentation, and artificial spiking neurons.