2015
CD44 Influences Fibroblast Behaviors Via Modulation of Cell–Cell and Cell–Matrix Interactions, Affecting Survivin and Hippo Pathways
Tsuneki M, Madri JA. CD44 Influences Fibroblast Behaviors Via Modulation of Cell–Cell and Cell–Matrix Interactions, Affecting Survivin and Hippo Pathways. Journal Of Cellular Physiology 2015, 231: 731-743. PMID: 26248063, DOI: 10.1002/jcp.25123.Peer-Reviewed Original ResearchConceptsHippo pathwayN-cadherinCaspase-3Cell-matrix interactionsSiRNA knock-downCollagen type IPivotal roleNon-coated dishesKnock-downExtracellular matrix expressionHigh cell densitySiRNA knockdownCell adhesionCell behaviorCell typesDiverse arrayPhospho-YAPNuclear fractionRole of CD44Fibroblast migrationFibroblast behaviorType IMesenchymal tissuePathwayCells cells
1998
Immunofluorescence Characterization of Key Extracellular Matrix Proteins in Murine Bone Marrow In Situ
Nilsson S, Debatis M, Dooner M, Madri J, Quesenberry P, Becker P. Immunofluorescence Characterization of Key Extracellular Matrix Proteins in Murine Bone Marrow In Situ. Journal Of Histochemistry & Cytochemistry 1998, 46: 371-377. PMID: 9487119, DOI: 10.1177/002215549804600311.Peer-Reviewed Original ResearchConceptsExtracellular matrix proteinsMatrix proteinsKey extracellular matrix proteinsParticular extracellular matrix proteinsExtracellular matrix protein fibronectinStem cellsCentral marrow regionsMatrix protein fibronectinStem cell proliferationCollagen type IMurine bone marrowHemopoietic stem cellsProtein fibronectinBone marrow vesselsExtracellular matrixBone marrowMechanistic roleCell proliferationProteinMarrow microenvironmentImportant mechanistic roleMolecular interactionsImmunofluorescence labelingCollagen type IVType I
1996
Laminin promotes differentiation of NB4 promyelocytic leukemia cells with all-trans retinoic acid.
Becker P, Li Z, Potselueva T, Madri J, Newburger P, Berliner N. Laminin promotes differentiation of NB4 promyelocytic leukemia cells with all-trans retinoic acid. Blood 1996, 88: 261-7. PMID: 8704182, DOI: 10.1182/blood.v88.1.261.bloodjournal881261.Peer-Reviewed Original ResearchMeSH KeywordsAntigens, CDBase SequenceCalciumCell Culture TechniquesCell DifferentiationCell DivisionCollagenDrug SynergismFibronectinsGene Expression Regulation, LeukemicHumansIntegrin alpha6Integrin beta1IonomycinIonophoresLamininLeukemia, Promyelocytic, AcuteMolecular Sequence DataNeoplasm ProteinsNeoplastic Stem CellsOxidation-ReductionPolymerase Chain ReactionReceptors, LamininTretinoinTumor Cells, CulturedConceptsAlpha 6 integrinTrans retinoic acidNB4 promyelocytic leukemia cellsPromyelocytic leukemia cellsMorphologic maturationLeukemia cellsRetinoic acidReverse transcription-polymerase chain reactionTranscription-polymerase chain reactionSecondary granule proteinsPresence of ionomycinPromyelocytic leukemia cell lineHistologic appearanceHours of exposureLeukemia cell linesMinimal maturationFlow cytometryHigh-level surface expressionDifferentiation agentsCollagen type INB4 cellsLaminin receptorATRAExtracellular matrix componentsCell proliferationLaminin promotes differentiation of NB4 promyelocytic leukemia cells with all-trans retinoic acid
Becker P, Li Z, Potselueva T, Madri J, Newburger P, Berliner N. Laminin promotes differentiation of NB4 promyelocytic leukemia cells with all-trans retinoic acid. Blood 1996, 88: 261-267. DOI: 10.1182/blood.v88.1.261.261.Peer-Reviewed Original ResearchAlpha 6 integrinTrans retinoic acidNB4 promyelocytic leukemia cellsPromyelocytic leukemia cellsMorphologic maturationLeukemia cellsRetinoic acidReverse transcription-polymerase chain reactionTranscription-polymerase chain reactionSecondary granule proteinsPresence of ionomycinPromyelocytic leukemia cell lineHistologic appearanceHours of exposureLeukemia cell linesMinimal maturationFlow cytometryHigh-level surface expressionDifferentiation agentsCollagen type INB4 cellsLaminin receptorATRAExtracellular matrix componentsCell proliferation
1992
Human enterocyte (Caco-2) migration is modulated in vitro by extracellular matrix composition and epidermal growth factor.
Basson M, Modlin I, Madri J. Human enterocyte (Caco-2) migration is modulated in vitro by extracellular matrix composition and epidermal growth factor. Journal Of Clinical Investigation 1992, 90: 15-23. PMID: 1634605, PMCID: PMC443057, DOI: 10.1172/jci115828.Peer-Reviewed Original ResearchConceptsEpidermal growth factorCaco-2 cellsGrowth factorEGF treatmentEnterocyte migrationHuman colonic cell lineColonic cell lineAlpha 2 subunitIntegrin surface expressionEGF-treated cellsAlpha integrin subunitsCollagen I.Functional antibodiesCell surface receptorsCollagen type IIntegrin expressionAlpha 2Basal migrationCell proliferationSurface expressionCollagen IExtracellular matrix compositionCell linesIntegrin subunitsSurface receptors
1987
The Basement Membrane Underlying the Vascular Endothelium Is Not Thrombogenic: In Vivo and In Vitro Studies with Rabbit and Human Tissue
Buchanan M, Richardson M, Haas T, Hirsh J, Madri J. The Basement Membrane Underlying the Vascular Endothelium Is Not Thrombogenic: In Vivo and In Vitro Studies with Rabbit and Human Tissue. Thrombosis And Haemostasis 1987, 58: 698-704. PMID: 3672420, DOI: 10.1055/s-0038-1645958.Peer-Reviewed Original ResearchConceptsEndothelial cellsPlatelet accumulationAir perfusionBalloon catheter injuryBasement membraneRabbit carotid arteryCatheter strippingCatheter injuryPerfusion injuryHuman endothelial cellsPlatelet reactivityInteraction of plateletsCarotid arteryElectron microscopic examinationVascular endotheliumTransmission electron microscopic examinationPlatelet adhesionCollagen type IInjuryOne hourConflicting resultsMicroscopic examinationSubendotheliumBasement membrane componentsVivo
1986
Collagen types I, III, and V in human embryonic and fetal skin
Smith L, Holbrook K, Madri J. Collagen types I, III, and V in human embryonic and fetal skin. Developmental Dynamics 1986, 175: 507-521. PMID: 3521252, DOI: 10.1002/aja.1001750409.Peer-Reviewed Original ResearchConceptsDermal-epidermal junctionReticular regionsType IIIFetal skinType IType VCollagen type IWeeks of gestationSubdermal connective tissueAdult-like patternLarge diameter fibrilsGestational ageFirst trimesterImmunoperoxidase dataPapillary regionImmunoperoxidase stainingType III collagenFetal ageFibrillar collagenLight microscope levelBlood vesselsConnective tissueDermal collagen fibrilsCollagen fibrilsType V collagen
1985
Immunolocalization of type IV collagen and laminin in nonbasement membrane structures of murine corneal stroma. A light and electron microscopic study.
Pratt B, Madri J. Immunolocalization of type IV collagen and laminin in nonbasement membrane structures of murine corneal stroma. A light and electron microscopic study. Laboratory Investigation 1985, 52: 650-6. PMID: 3892156.Peer-Reviewed Original ResearchConceptsElectron microscopic immunolocalizationMicrofibril bundlesInterstitial collagen types IType IV collagenPossible functionsExtracellular matrixImmunofluorescent localizationMembrane structureIV collagenCollagen type IType IType V collagenOxytalan microfibrilsImmunolocalizationCellular sourceMicrofibrilsLaminin
1981
The immune response to human type III and type V (AB2) collagen: antigenic determinants and genetic control in mice
Kemp J, Madri J. The immune response to human type III and type V (AB2) collagen: antigenic determinants and genetic control in mice. European Journal Of Immunology 1981, 11: 90-94. PMID: 6163643, DOI: 10.1002/eji.1830110205.Peer-Reviewed Original ResearchConceptsAntibody responseSpecific IgG antibody responseAntigenic determinantsIgG antibody responseHigher antibody responseT cell recognitionType IIIType IHuman type IIIHigh-affinity monoclonal antibodiesAntigen presentationImmune responseBovine collagen type IMonoclonal antibodiesCollagen type IIr genesType V collagenCell recognitionHuman collagenFurther studiesConnective tissue biologyTissue biologyMicePresent studyCollagen