2006
Antenatal risk factors, cytokines and the development of atopic disease in early childhood
Chung E, Miller R, Wilson M, McGeady S, Culhane J. Antenatal risk factors, cytokines and the development of atopic disease in early childhood. Archives Of Disease In Childhood - Fetal And Neonatal Edition 2006, 92: f68. PMID: 17185433, PMCID: PMC2675311, DOI: 10.1136/adc.2006.106492.Peer-Reviewed Original ResearchConceptsAtopic diseasesRisk factorsAntenatal exposureT helper cell type 1T helper cell type 2 cytokinesPediatric atopic diseaseNeonatal immune responsesAntenatal risk factorsType 2 cytokinesCell type 1Early childhoodTh2 pathwayCytokine responsesEnvironmental allergensCord bloodIntrauterine environmentImmune responseGenetic predispositionPsychosocial factorsType 1DiseaseCytokinesChildhoodExposureCurrent understanding
2004
Stillbirth: a review
Goldenberg R, Kirby R, Culhane J. Stillbirth: a review. The Journal Of Maternal-Fetal & Neonatal Medicine 2004, 16: 79-94. DOI: 10.1080/jmf.16.2.79.94.Peer-Reviewed Original ResearchConceptsRisk factorsAdverse pregnancy outcomesCauses of stillbirthRate of stillbirthCause of deathEarly fetal deathIntrapartum fetal monitoringAntepartum monitoringCesarean sectionPlacental examinationPregnancy outcomesFetal deathPatient counselingFuture pregnanciesCongenital anomaliesEarly deliveryFetal monitoringStillbirthEarly detectionDeathRiskCausePregnancyFetusesFactorsStillbirth: a review.
Goldenberg R, Kirby R, Culhane J. Stillbirth: a review. The Journal Of Maternal-Fetal & Neonatal Medicine 2004, 16: 79-94. PMID: 15512717, DOI: 10.1080/14767050400003801.Peer-Reviewed Original ResearchConceptsRisk factorsAdverse pregnancy outcomesCauses of stillbirthRate of stillbirthCause of deathEarly fetal deathIntrapartum fetal monitoringAntepartum monitoringCesarean sectionPlacental examinationPregnancy outcomesFetal deathPatient counselingFuture pregnanciesCongenital anomaliesEarly deliveryFetal monitoringStillbirthEarly detectionDeathRiskCausePregnancyFetusesFactors
2003
Role of Psychosocial and Nutritional Stress on Poor Pregnancy Outcome
Hobel C, Culhane J. Role of Psychosocial and Nutritional Stress on Poor Pregnancy Outcome. Journal Of Nutrition 2003, 133: 1709s-1717s. PMID: 12730488, DOI: 10.1093/jn/133.5.1709s.Peer-Reviewed Original ResearchConceptsCorticotropin-releasing hormoneLow birth weightPreterm birthBirth weightAge-matched control subjectsRole of PsychosocialIndependent risk factorMaternal psychosocial stressPoor pregnancy outcomesStrenuous physical activityInitiation of laborElevated corticotropin-releasing hormonePlausible biological pathwaysPreterm laborPregnancy outcomesImmunomodulatory effectsControl subjectsEpidemiological evidenceRisk factorsClinical studiesPhysical activityEpidemiological dataMaternal stressPsychosocial stressClinical programs
2001
Stress, infection and preterm birth: a biobehavioural perspective
Wadhwa P, Culhane J, Rauh V, Barve S, Hogan V, Sandman C, Hobel C, Chicz‐DeMet A, Dunkel‐Schetter C, Garite T, Glynn L. Stress, infection and preterm birth: a biobehavioural perspective. Paediatric And Perinatal Epidemiology 2001, 15: 17-29. PMID: 11520397, DOI: 10.1046/j.1365-3016.2001.00005.x.Peer-Reviewed Original ResearchConceptsPreterm birthMaternal stressImmune processesPlacental corticotropin-releasing hormoneFetal endocrine systemObstetric risk assessmentIndependent risk factorSpontaneous preterm birthSpontaneous preterm deliveryPro-inflammatory mechanismsCorticotropin-releasing hormoneInfectious-inflammatory processMaternal-child healthUrogenital tract infectionsChronic maternal stressPreterm parturitionPreterm deliveryTract infectionsLocal immunityPregnant womenInflammatory pathwaysRisk factorsPhysiology of parturitionEpidemiological studiesPathophysiological eventsMaternal Stress is Associated With Bacterial Vaginosis in Human Pregnancy
Culhane J, Rauh V, McCollum K, Hogan V, Agnew K, Wadhwa P. Maternal Stress is Associated With Bacterial Vaginosis in Human Pregnancy. Maternal And Child Health Journal 2001, 5: 127-134. PMID: 11573838, DOI: 10.1023/a:1011305300690.Peer-Reviewed Original ResearchConceptsChronic maternal stressBacterial vaginosisMaternal stressRisk factorsMaternal infectionBV statusPresence of BVChronic stressMultivariable logistic regression modelHigher chronic stress levelsIntermediate vaginal floraAdverse perinatal outcomesBehavioral risk factorsMaternal sociodemographic variablesCohen's Perceived Stress ScaleModerate stress groupLogistic regression modelsRace/ethnicityLow stress groupPerinatal outcomesIndependent predictorsWeeks' gestationHigh stress groupHuman pregnancyPregnant womenStress and Preterm Birth: Neuroendocrine, Immune/Inflammatory, and Vascular Mechanisms
Wadhwa P, Culhane J, Rauh V, Barve S. Stress and Preterm Birth: Neuroendocrine, Immune/Inflammatory, and Vascular Mechanisms. Maternal And Child Health Journal 2001, 5: 119-125. PMID: 11573837, DOI: 10.1023/a:1011353216619.Peer-Reviewed Original Research