p204, a p200 family protein, as a multifunctional regulator of cell proliferation and differentiation
Luan Y, Lengyel P, Liu CJ. p204, a p200 family protein, as a multifunctional regulator of cell proliferation and differentiation. Cytokine & Growth Factor Reviews 2008, 19: 357-369. PMID: 19027346, PMCID: PMC4442486, DOI: 10.1016/j.cytogfr.2008.11.002.Peer-Reviewed Original ResearchConceptsP200-family proteinsFamily proteinsAmino acid-long C-terminal domainLong C-terminal domainTissue-specific transcription factorsCell proliferationInterferon-inducible p200 familyTissue differentiationC-terminal domainMurine memberRas proteinsSubcellular compartmentsTranscription factorsHuman proteinsMultifunctional regulatorHomologous mouseTarget proteinsProteinTarget activityDifferentiationP204ProliferationTumor growthImportant roleFamilyMediation of Chondrogenic and Osteogenic Differentiation by an Interferon-Inducible p202 Protein
Kong L, Liu C. Mediation of Chondrogenic and Osteogenic Differentiation by an Interferon-Inducible p202 Protein. Cellular And Molecular Life Sciences 2008, 65: 3494-3506. PMID: 18791844, PMCID: PMC11131663, DOI: 10.1007/s00018-008-8342-5.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell DifferentiationCell LineChondrocytesChondrogenesisFeedback, PhysiologicalGene Expression Regulation, DevelopmentalGene Knockdown TechniquesGenes, ReporterGrowth PlateIntracellular Signaling Peptides and ProteinsMiceMice, Inbred C3HMice, KnockoutMice, TransgenicOsteoblastsOsteogenesisParathyroid Hormone-Related ProteinPluripotent Stem CellsRNA, Small InterferingSmad ProteinsConceptsParathyroid hormone-related peptideExpression of PTHrPHormone-related peptideCourse of osteogenesisGrowth plate chondrocytesInterferon-inducible proteinMolecular mechanism studiesInterferon-inducible p200 familyImportant mediatorP202 proteinOsteogenic differentiationSiRNA approachMouse embryosP202 expressionChondrocyte differentiationPositive feedback loopSmad transcription factorsTransgenic mouse embryosOsteoblast differentiationDifferential expressionExpressionC3H10T1/2 cellsC2C12 cellsDifferentiationCells