2011
Negative and Nonemotional Interference with Visual Working Memory in Schizophrenia
Anticevic A, Repovs G, Corlett PR, Barch DM. Negative and Nonemotional Interference with Visual Working Memory in Schizophrenia. Biological Psychiatry 2011, 70: 1159-1168. PMID: 21861986, DOI: 10.1016/j.biopsych.2011.07.010.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmygdalaAnalysis of VarianceArousalAttentionCase-Control StudiesCerebral CortexDiscrimination, PsychologicalEmotionsFemaleField Dependence-IndependenceHumansLinear ModelsMagnetic Resonance ImagingMaleMatched-Pair AnalysisMemory, Short-TermMiddle AgedReference ValuesSchizophreniaSchizophrenic PsychologyVisual PerceptionConceptsControl subjectsSCZ subjectsDSM-IV-diagnosed schizophreniaAberrant salience processingLevel-dependent imagingAbility of patientsFunctional magnetic resonance imagingMagnetic resonance imagingPosterior cortical regionsFunctional magnetic resonanceLevel-dependent activityPathophysiological mechanismsPatientsResonance imagingCortical regionsAberrant responsesSalience processingSchizophreniaPrefrontal regionsEffects of distractionSubjectsSpecific deficitsDeficitsMagnetic resonanceSimilar responsesEmotion Effects on Attention, Amygdala Activation, and Functional Connectivity in Schizophrenia
Anticevic A, Repovs G, Barch DM. Emotion Effects on Attention, Amygdala Activation, and Functional Connectivity in Schizophrenia. Schizophrenia Bulletin 2011, 38: 967-980. PMID: 21415225, PMCID: PMC3446234, DOI: 10.1093/schbul/sbq168.Peer-Reviewed Original ResearchConceptsAmygdala activationAmygdala recruitmentEmotional processingSimple perceptual decision tasksHigh-level cognitive processesFunctional connectivityRapid event-related fMRIPerceptual decision taskTask-based functional connectivityProcessing of affectEvent-related fMRIMinimal cognitive loadSCZ subjectsLevel of behaviorSignificant group differencesEmotion effectsNeutral distractionAffective cuesMoment perceptionsAffective stimuliNegative stimuliCognitive processesDecision taskNegative distractionCognitive load
2010
Amygdala Recruitment in Schizophrenia in Response to Aversive Emotional Material: A Meta-analysis of Neuroimaging Studies
Anticevic A, Van Snellenberg JX, Cohen RE, Repovs G, Dowd EC, Barch DM. Amygdala Recruitment in Schizophrenia in Response to Aversive Emotional Material: A Meta-analysis of Neuroimaging Studies. Schizophrenia Bulletin 2010, 38: 608-621. PMID: 21123853, PMCID: PMC3329999, DOI: 10.1093/schbul/sbq131.Peer-Reviewed Original ResearchConceptsAmygdala activationCritical clinical featuresGroup differencesAbnormal amygdala activationClinical featuresSchizophrenia showPatientsBilateral amygdalaMeta-AnalysisIntact recruitmentNeuroimaging studiesSchizophreniaMeta-analytic approachEmotional dysfunctionAmygdala recruitmentDysfunctionPresent findingsAmygdalaEmotional stimuliNumber of studiesActivationFormal meta-analytic approachRecruitmentResponseStimuliResisting emotional interference: Brain regions facilitating working memory performance during negative distraction
Anticevic A, Barch D, Repovs G. Resisting emotional interference: Brain regions facilitating working memory performance during negative distraction. Cognitive, Affective, & Behavioral Neuroscience 2010, 10: 159-173. PMID: 20498341, PMCID: PMC3856369, DOI: 10.3758/cabn.10.2.159.Peer-Reviewed Original ResearchConceptsPrefrontal cortical regionsNegative distractionPrefrontal regionsEmotional interferenceNeutral distractionIncorrect trialsCortical regionsPrefrontal cortexNegative emotional distractionActive cognitive engagementLateral prefrontal regionsVentrolateral prefrontal regionsFrontopolar prefrontal cortexSurvival-relevant informationParietal cortical regionsEmotional distractionWM performanceCognitive operationsAmygdala signalMemory performanceCognitive engagementIndividual differencesAmygdala activityActivation differencesMore deactivation