2024
Functional magnetic resonance imaging in schizophrenia: current evidence, methodological advances, limitations and future directions
Voineskos A, Hawco C, Neufeld N, Turner J, Ameis S, Anticevic A, Buchanan R, Cadenhead K, Dazzan P, Dickie E, Gallucci J, Lahti A, Malhotra A, Öngür D, Lencz T, Sarpal D, Oliver L. Functional magnetic resonance imaging in schizophrenia: current evidence, methodological advances, limitations and future directions. World Psychiatry 2024, 23: 26-51. PMID: 38214624, PMCID: PMC10786022, DOI: 10.1002/wps.21159.Peer-Reviewed Original ResearchFunctional magnetic resonance imagingFunctional neuroimagingFunctional magnetic resonance imaging studyStudy of negative symptomsClinical high-risk phaseFMRI biomarkersSocial cognitive deficitsNeurobiology of schizophreniaHeterogeneity of schizophreniaRegional brain activityMagnetic resonance imagingPersistent functional impairmentTreatment response studiesAntipsychotic medicationNegative symptomsSchizophrenia treatmentCognitive deficitsSchizophreniaBrain activityPsychosocial interventionsNeural markersResonance imagingHigh-risk phaseReview researchCase-control comparison
2012
A broken filter: Prefrontal functional connectivity abnormalities in schizophrenia during working memory interference
Anticevic A, Repovs G, Krystal JH, Barch DM. A broken filter: Prefrontal functional connectivity abnormalities in schizophrenia during working memory interference. Schizophrenia Research 2012, 141: 8-14. PMID: 22863548, PMCID: PMC3879404, DOI: 10.1016/j.schres.2012.07.007.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalysis of VarianceBrain MappingFemaleFunctional LateralityHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMemory DisordersMemory, Short-TermMiddle AgedNerve NetNeural PathwaysNeuropsychological TestsOxygenPrefrontal CortexSchizophreniaSchizophrenic PsychologyConceptsFunctional connectivity abnormalitiesConnectivity abnormalitiesMedio-dorsal thalamusTask-based functional connectivityFinal common pathwayMaintenance phasePrefrontal cortical regionsDorsolateral prefrontal cortex activationPrefrontal cortex activationFunctional deficitsHealthy controlsSub-cortical regionsExtended amygdalaPatientsCortex activationCognitive deficitsCortical regionsFunctional connectivityLife outcomesAbnormalitiesDLPFC networkCommon pathwaySchizophrenia researchSchizophreniaMemory abnormalities
2011
Variable Global Dysconnectivity and Individual Differences in Schizophrenia
Cole MW, Anticevic A, Repovs G, Barch D. Variable Global Dysconnectivity and Individual Differences in Schizophrenia. Biological Psychiatry 2011, 70: 43-50. PMID: 21496789, PMCID: PMC3204885, DOI: 10.1016/j.biopsych.2011.02.010.Peer-Reviewed Original ResearchConceptsIndividual differencesWechsler Adult Intelligence Scale-Third EditionDorsolateral prefrontal cortex regionsState functional connectivity magnetic resonanceFunctional connectivity magnetic resonanceFocal brain regionsPrefrontal cortex regionsSternberg taskCognitive functioningPFC involvementCognitive deficitsDSM-IV schizophreniaSymptom domainsConnectivity methodsBrain regionsNegative symptomsSymptom severitySymptom presentationCortex regionsDysconnectivityHub regionsNeuropathology of schizophreniaSchizophreniaSuch findingsSymptom expression