2024
249. Interactive Effects of Motivation and Cognition in Adolescents With Depression and Neurotypical Peers
Pham P, Frazier A, Agrawal S, Anticevic A, Cho Y. 249. Interactive Effects of Motivation and Cognition in Adolescents With Depression and Neurotypical Peers. Biological Psychiatry 2024, 95: s201. DOI: 10.1016/j.biopsych.2024.02.484.Peer-Reviewed Original Research
2012
The role of default network deactivation in cognition and disease
Anticevic A, Cole MW, Murray JD, Corlett PR, Wang XJ, Krystal JH. The role of default network deactivation in cognition and disease. Trends In Cognitive Sciences 2012, 16: 584-592. PMID: 23142417, PMCID: PMC3501603, DOI: 10.1016/j.tics.2012.10.008.Peer-Reviewed Original ResearchConceptsDMN suppressionDefault network deactivationGoal-directed cognitionSpecific behavioral tasksDefault mode networkCognitive neurosciencePharmacological neuroimagingSuppression deficitsBehavioral tasksFocused attentionClinical neuroscienceTheoretical neuroscienceBrain regionsNeuroscienceCognitionSevere mental illnessMental illnessConsiderable bodyNeuroimagingTaskDeficitsDMNExternal environmentMindDiseaseNMDA receptor function in large-scale anticorrelated neural systems with implications for cognition and schizophrenia
Anticevic A, Gancsos M, Murray JD, Repovs G, Driesen NR, Ennis DJ, Niciu MJ, Morgan PT, Surti TS, Bloch MH, Ramani R, Smith MA, Wang XJ, Krystal JH, Corlett PR. NMDA receptor function in large-scale anticorrelated neural systems with implications for cognition and schizophrenia. Proceedings Of The National Academy Of Sciences Of The United States Of America 2012, 109: 16720-16725. PMID: 23012427, PMCID: PMC3478611, DOI: 10.1073/pnas.1208494109.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlgorithmsBrainCognitionDouble-Blind MethodExcitatory Amino Acid AntagonistsFemaleHumansInfusions, IntravenousKetamineMagnetic Resonance ImagingMaleMemoryModels, NeurologicalPattern Recognition, VisualPsychomotor PerformanceReceptors, N-Methyl-D-AspartateSchizophreniaSynaptic TransmissionYoung AdultConceptsNeural systemsLarge-scale brain systemsTask-dependent activationN-methyl-D-aspartate receptorsRealistic computational modelingSevere neuropsychiatric illnessNMDA glutamate receptor antagonistGlutamate receptor antagonistsBrain systemsNMDA receptor functionTask performanceMultiple interacting regionsCognitionCortical disinhibitionGlutamatergic neurotransmissionReceptor antagonistCortical computationGlutamate's roleReciprocal relationshipNeuropsychiatric illnessLocal circuitsReceptor functionSchizophreniaPresent findingsComputational modeling