2021
DnaJ and ClpX Are Required for HitRS and HssRS Two-Component System Signaling in Bacillus anthracis
Laut C, Leasure C, Pi H, Carlin S, Chu M, Hillebrand G, Lin H, Yi X, Stauff D, Skaar E. DnaJ and ClpX Are Required for HitRS and HssRS Two-Component System Signaling in Bacillus anthracis. Infection And Immunity 2021, 90: e00560-21. PMID: 34748369, PMCID: PMC8788696, DOI: 10.1128/iai.00560-21.Peer-Reviewed Original ResearchConceptsTwo-component systemGene expressionSubstrate-binding subunitSignal transduction activityTarget gene expressionB. anthracisBacillus anthracisGram-positive bacteriumHost-induced stressesClpXP proteaseProtein chaperonesSignal transductionClpXGene productsTransduction activityDnaJVertebrate hostsHeme levelsHomeostasis regulatorGenetic selectionHigh heme levelsCell envelope disruptionBioterror weaponHssRSAnthracis
2019
The global distribution of Bacillus anthracis and associated anthrax risk to humans, livestock and wildlife
Carlson C, Kracalik I, Ross N, Alexander K, Hugh-Jones M, Fegan M, Elkin B, Epp T, Shury T, Zhang W, Bagirova M, Getz W, Blackburn J. The global distribution of Bacillus anthracis and associated anthrax risk to humans, livestock and wildlife. Nature Microbiology 2019, 4: 1337-1343. PMID: 31086311, DOI: 10.1038/s41564-019-0435-4.Peer-Reviewed Original ResearchConceptsAnthrax riskWild ungulatesDistribution of B. anthracisInadequate surveillance systemsGlobal distributionOccurrence datasetConservation effortsLivestock vulnerabilityTemperate landsGrazing livestockHuman healthGeographic extentGlobal totalRegression treesWildlifeUngulatesVulnerable regionsLivestockAnthrax outbreaksNorth AmericaRainfed systemsBillion peopleLandscapeLandTemperate
2018
Spores and soil from six sides: interdisciplinarity and the environmental biology of anthrax (Bacillus anthracis)
Carlson C, Getz W, Kausrud K, Cizauskas C, Blackburn J, Carrillo F, Colwell R, Easterday W, Ganz H, Kamath P, Økstad O, Turner W, Kolstø A, Stenseth N. Spores and soil from six sides: interdisciplinarity and the environmental biology of anthrax (Bacillus anthracis). Biological Reviews 2018, 93: 1813-1831. PMID: 29732670, DOI: 10.1111/brv.12420.Peer-Reviewed Original ResearchConceptsEnvironmental persistenceLong Term Ecological Research siteBiology of Bacillus anthracisBacillus cereus biovar anthracisPatterns of vegetationEtosha National ParkEcological Research siteEnvironmentally transmitted diseasesLong-term persistenceAnthrax riskAnthrax seasonalityHerbivorous hostsDecades of surveillanceHerbivore communitiesAnthrax dynamicsEcosystem structureConservation effortsCarcass depositionNational ParkEcological roleSpore banksDisease ecologyGreen-upHerbivoresSoil
2003
Emergency response to an anthrax attack
Wein LM, Craft DL, Kaplan EH. Emergency response to an anthrax attack. Proceedings Of The National Academy Of Sciences Of The United States Of America 2003, 100: 4346-4351. PMID: 12651951, PMCID: PMC153095, DOI: 10.1073/pnas.0636861100.Peer-Reviewed Original Research
2002
Fatal Inhalational Anthrax in a 94-Year-Old Connecticut Woman
Barakat LA, Quentzel HL, Jernigan JA, Kirschke DL, Griffith K, Spear SM, Kelley K, Barden D, Mayo D, Stephens DS, Popovic T, Marston C, Zaki SR, Guarner J, Shieh WJ, Carver HW, Meyer RF, Swerdlow DL, Mast EE, Hadler JL, Team F. Fatal Inhalational Anthrax in a 94-Year-Old Connecticut Woman. JAMA 2002, 287: 863-868. PMID: 11851578, DOI: 10.1001/jama.287.7.863.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnthraxAutopsyBacillus anthracisBioterrorismConnecticutDNA, BacterialEnvironmental ExposureFatal OutcomeFemaleHemorrhageHumansLymph NodesMediastinal DiseasesMediastinumNecrosisPleural EffusionPulmonary EdemaRadiographyRespiratory InsufficiencyRespiratory Tract InfectionsSpores, BacterialConceptsClinical courseInhalational anthraxBioterrorism-related inhalational anthraxMediastinal lymph nodesPatient's clinical courseAdministration of antibioticsSources of exposureRespiratory insufficiencyAntibiotic therapyIll patientsLymph nodesClinical featuresPleural effusionPulmonary edemaBlood culturesConnecticut womenDiagnostic testsPatientsB anthracisWomenExposureBacteremiaEdemaAnthraxEffusion
2001
Cutaneous Bacillus anthracis Infection
Gallagher T, Strober B. Cutaneous Bacillus anthracis Infection. New England Journal Of Medicine 2001, 345: 1646-1647. PMID: 11704683, DOI: 10.1056/nejmc012978.Peer-Reviewed Original Research
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