2024
Efficient deep learning-based automated diagnosis from echocardiography with contrastive self-supervised learning
Holste G, Oikonomou E, Mortazavi B, Wang Z, Khera R. Efficient deep learning-based automated diagnosis from echocardiography with contrastive self-supervised learning. Communications Medicine 2024, 4: 133. PMID: 38971887, PMCID: PMC11227494, DOI: 10.1038/s43856-024-00538-3.Peer-Reviewed Original ResearchSelf-supervised learningTransfer learningTraining dataEchocardiogram videosPortion of labelled dataStandard transfer learning approachContrastive self-supervised learningSelf-supervised learning approachLearning approachImage recognition tasksState-of-the-artContrastive learning approachFine-tuningTransfer learning approachMedical image diagnosisCardiac disease diagnosisContrastive learningVideo framesLabeled datasetLabeled dataExpert labelsClassification performanceMedical imagesRecognition taskVideoDopamine D1 Receptor Agonists Rescue Age-related Decline in Temporal Order Memory
Bransom L, Bassett A, Zhou M, Cimino J, Mailman R, Yang Y. Dopamine D1 Receptor Agonists Rescue Age-related Decline in Temporal Order Memory. Neuroscience 2024, 551: 177-184. PMID: 38823551, PMCID: PMC11246218, DOI: 10.1016/j.neuroscience.2024.05.033.Peer-Reviewed Original ResearchTemporal order memoryOrder memoryAge-related declineDopamine D1 receptor agonistTreating age-related cognitive declineAge-related cognitive declineReceptor agonistsSpatial working memoryD1 receptor agonistPoorer memory performanceWorking memoryMemory performanceCognitive declineEffects of ageRecognition taskEffect sizeIndividual ratsMemoryOld ratsOptimal effective doseDopamineImproved therapeutic indexAgonistsTherapeutic indexFunctional selectivity
2023
Investigating the Face Inversion Effect in Autism Across Behavioral and Neural Measures of Face Processing
Griffin J, Azu M, Cramer-Benjamin S, Franke C, Herman N, Iqbal R, Keifer C, Rosenthal L, McPartland J. Investigating the Face Inversion Effect in Autism Across Behavioral and Neural Measures of Face Processing. JAMA Psychiatry 2023, 80: 1026-1036. PMID: 37405787, PMCID: PMC10323765, DOI: 10.1001/jamapsychiatry.2023.2105.Peer-Reviewed Original ResearchFace processing systemFace inversion effectAutism spectrum disorderInversion effectFace processingNeurotypical sampleAutistic individualsEffect sizeHuman social cognitionPerformance differencesFace recognition taskPerformance-based measuresSocial cognitionNeural measuresNeurotypical individualsPsychological constructsNeural responsesSpectrum disorderElectrophysiological measuresRecognition taskBrain functioningBehavioral paradigmsRecognition demandsIdentity recognitionNeural systemsExamining the association between exposome score for schizophrenia and cognition in schizophrenia, siblings, and healthy controls: Results from the EUGEI study
Fusar-Poli L, Prachason T, Erzin G, Pries L, Brondino N, Politi P, Delespaul P, Kenis G, Luykx J, Lin B, Richards A, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran E, Kaymak S, Mihaljevic M, Andric-Petrovic S, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz P, García-Portilla M, Sanjuan J, Escarti M, Santos J, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric N, Atbaşoğlu C, Üçok A, Alptekin K, Saka M, Arango C, O'Donovan M, van Os J, Rutten B, Guloksuz S, investigators G. Examining the association between exposome score for schizophrenia and cognition in schizophrenia, siblings, and healthy controls: Results from the EUGEI study. Psychiatry Research 2023, 323: 115184. PMID: 37015164, DOI: 10.1016/j.psychres.2023.115184.Peer-Reviewed Original ResearchConceptsBenton Facial Recognition TestDegraded Facial Affect Recognition TaskWechsler Adult Intelligence Scale-Third EditionSchizophrenia spectrum disordersSocial cognitionCognitive domainsFacial affect recognition taskAffect recognition taskFacial Recognition TestCognitive impairmentRecognition testSpectrum disorderRecognition taskCross-sectional sampleHealthy controlsCognitionPsychosis spectrumShort versionUnaffected siblingsNeurocognitionEUGEI studySchizophreniaPerceptionImpairmentSiblingsExamining the association between exposome score for schizophrenia and cognition in schizophrenia, siblings, and healthy controls: Findings from the EUGEI study
Fusar-Poli L, Investigators E, Investigators G, van Os J, Rutten B, Guloksuz S. Examining the association between exposome score for schizophrenia and cognition in schizophrenia, siblings, and healthy controls: Findings from the EUGEI study. European Psychiatry 2023, 66: s445-s445. PMCID: PMC10434418, DOI: 10.1192/j.eurpsy.2023.957.Peer-Reviewed Original ResearchWechsler Adult Intelligence ScaleSchizophrenia spectrum disordersSocial cognitionFacial emotion recognition taskUnaffected siblingsEmotion recognition taskAdult Intelligence ScaleDisclosure of interestCognitive domainsIntelligence ScaleSpectrum disorderRecognition taskCognitionHealthy controlsNeurocognitionLongitudinal studyPresent cross-sectional studyEUGEI studyMolecular genetic riskSchizophrenia
2022
“Master” of None: Institutional Language Change Linked to Reduced Gender Bias
Bailey A, Dovidio J, LaFrance M. “Master” of None: Institutional Language Change Linked to Reduced Gender Bias. Journal Of Experimental Psychology Applied 2022, 28: 237-248. PMID: 34014722, DOI: 10.1037/xap0000326.Peer-Reviewed Original ResearchConceptsLanguage policy changeGeneric languageLanguage policesIncidence of menLanguage changeFace recognition taskActual menMale exemplarsLanguageGender biasGender inequityRecognition taskMore exemplarsLeadership rolesYale UniversityApplied contextExemplarsGeneric termMemoryPrevious experimental researchMindStudentsRange of processesReal-world policiesMen
2021
Examining facial emotion recognition as an intermediate phenotype for psychosis: Findings from the EUGEI study
Fusar-Poli L, Pries LK, van Os J, Erzin G, Delespaul P, Kenis G, Luykx JJ, Lin BD, Richards AL, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran EŞ, Kaymak SU, Mihaljevic MM, Andric-Petrovic S, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Üçok A, Alptekin K, Saka MC, investigators G, Aguglia E, Arango C, O'Donovan M, Rutten B, Guloksuz S. Examining facial emotion recognition as an intermediate phenotype for psychosis: Findings from the EUGEI study. Progress In Neuro-Psychopharmacology And Biological Psychiatry 2021, 113: 110440. PMID: 34536513, DOI: 10.1016/j.pnpbp.2021.110440.Peer-Reviewed Original ResearchConceptsDegraded Facial Affect Recognition TaskFacial emotion recognitionEmotion recognitionFacial affect recognition taskAffect recognition taskSocial cognition impairmentsFER deficitsIndividual emotionsPRS-SCZFER accuracyRecognition taskHealthy controlsSchizotypy-RevisedCognition impairmentIntermediate phenotypesPsychosis riskStructured interviewsEUGEI studySchizophreniaTotal scoreSiblingsGenetic riskDifferent patternsPsychosisEmotionsNeurobehavioral correlates of impaired emotion recognition in pediatric PTSD
Heyn SA, Schmit C, Keding TJ, Wolf R, Herringa RJ. Neurobehavioral correlates of impaired emotion recognition in pediatric PTSD. Development And Psychopathology 2021, 34: 946-956. PMID: 33487187, PMCID: PMC9717496, DOI: 10.1017/s0954579420001704.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderPediatric posttraumatic stress disorderTD youthFunctional connectivityImplicit emotion processing taskEmotion recognition taskImpaired emotion recognitionFunctional magnetic resonance imagingEmotion processing taskSample of youthNeutral facesAngry expressionsVisual attentionFMRI taskEmotion recognitionNeurobehavioral correlatesStress disorderNeurological substrateRecognition taskProcessing tasksYouth experienceMultimethod approachYouthImpaired abilityThreat recognition
2019
Acute Stress Throughout the Memory Cycle: Diverging Effects on Associative and Item Memory
Goldfarb EV, Tompary A, Davachi L, Phelps EA. Acute Stress Throughout the Memory Cycle: Diverging Effects on Associative and Item Memory. Journal Of Experimental Psychology General 2019, 148: 13-29. PMID: 30221962, PMCID: PMC6312485, DOI: 10.1037/xge0000472.Peer-Reviewed Original ResearchConceptsItem memoryAssociative memoryAssociative recognition taskAcute stressForms of memoryStress-induced cortisolAcute stress effectsNeutral objectsNegative wordsRecognition taskSubjective arousalSubjects designMemoryItemsDifferent patternsArousalAssociativeWordsTaskParticipantsStress effectsRelationshipCortisolQuadratic relationshipKey differences
2018
Clinical text annotation - what factors are associated with the cost of time?
Wei Q, Franklin A, Cohen T, Xu H. Clinical text annotation - what factors are associated with the cost of time? AMIA Annual Symposium Proceedings 2018, 2018: 1552-1560. PMID: 30815201, PMCID: PMC6371268.Peer-Reviewed Original ResearchConceptsAnnotation timeClinical textNatural language processing modelsClinical corpusIndividual user behaviorEntity recognition taskLanguage processing modelsPractice of annotationCharacteristics of sentencesClinical Text AnnotationText annotationsUser behaviorIndividual usersCost of timeActive learning researchRecognition taskLearning researchProcessing modelCost modelAnnotationUsersLimited workCorpusTextTaskExtracting psychiatric stressors for suicide from social media using deep learning
Du J, Zhang Y, Luo J, Jia Y, Wei Q, Tao C, Xu H. Extracting psychiatric stressors for suicide from social media using deep learning. BMC Medical Informatics And Decision Making 2018, 18: 43. PMID: 30066665, PMCID: PMC6069295, DOI: 10.1186/s12911-018-0632-8.Peer-Reviewed Original ResearchConceptsConvolutional neural networkRecurrent neural networkDeep learningConditional Random FieldsSupport vector machineSuicide-related tweetsClinical textNeural networkPsychiatric stressorsExtra TreesBinary classifierTransfer learning strategiesEntity recognition taskSocial mediaExact matchTraditional machineAnnotation costLearning strategiesRecognition problemSharing flowInexact matchVector machineTwitter dataRecognition taskTwitterRelationship between fMRI response during a nonverbal memory task and marijuana use in college students
Dager AD, Tice MR, Book GA, Tennen H, Raskin SA, Austad CS, Wood RM, Fallahi CR, Hawkins KA, Pearlson GD. Relationship between fMRI response during a nonverbal memory task and marijuana use in college students. Drug And Alcohol Dependence 2018, 188: 71-78. PMID: 29754029, PMCID: PMC6756147, DOI: 10.1016/j.drugalcdep.2018.03.025.Peer-Reviewed Original ResearchConceptsInferior frontal gyrusMJ usersFMRI responsesCollege studentsMemory taskMJ useFunctional magnetic resonance imaging (fMRI) responsesNonverbal memory tasksLower fMRI responseRecognition memoryNeural correlatesMagnetic resonance imaging responseFrontal gyrusVisual encodingRecognition taskOccupational functioningAge 18Memory dysfunctionMarijuana useAcademic performanceLeft hippocampusHippocampal dysfunctionGroup differencesRight hippocampusTask
2017
Alterations in visual cortical activation and connectivity with prefrontal cortex during working memory updating in major depressive disorder
Le TM, Borghi JA, Kujawa AJ, Klein DN, Leung HC. Alterations in visual cortical activation and connectivity with prefrontal cortex during working memory updating in major depressive disorder. NeuroImage Clinical 2017, 14: 43-53. PMID: 28138426, PMCID: PMC5257188, DOI: 10.1016/j.nicl.2017.01.004.Peer-Reviewed Original ResearchConceptsVisual association areasMemory updatingPrefrontal cortexAssociation areasIrrelevant negative informationMajor depressive disorderPrefrontal cortical activityFunctional magnetic resonanceVisual cortical activationMDD groupCognitive controlNeutral facesEmotion processingTask stimuliGreater ruminationRecognition testCore clinical featuresPerformance deficitsRecognition taskNegative informationMore persistent activationAbnormal affectTask informationUnmedicated participantsCortical activation
2016
Cannabinoids reverse the effects of early stress on neurocognitive performance in adulthood
Alteba S, Korem N, Akirav I. Cannabinoids reverse the effects of early stress on neurocognitive performance in adulthood. Learning & Memory 2016, 23: 349-358. PMID: 27317195, PMCID: PMC4918780, DOI: 10.1101/lm.041608.116.Peer-Reviewed Original ResearchConceptsEarly life stressLate adolescenceRecognition taskLife stressCannabinoid CB1/2 receptor agonistNovel object recognition taskEffects of ELSSocial recognition taskShort-term memoryCB1/2 receptor agonistObject recognition taskAnxiety-related disordersStress-induced impairmentRecognition memoryFear circuitImpaired performanceNeurocognitive performanceTreatment of stressCognitive deficitsNeurocognitive functionAnxiety levelsCB1 receptorsEarly stressPFC GRSpatial location
2014
Evaluating Word Representation Features in Biomedical Named Entity Recognition Tasks
Tang B, Cao H, Wang X, Chen Q, Xu H. Evaluating Word Representation Features in Biomedical Named Entity Recognition Tasks. BioMed Research International 2014, 2014: 240403. PMID: 24729964, PMCID: PMC3963372, DOI: 10.1155/2014/240403.Peer-Reviewed Original ResearchConceptsBiomedical Named Entity RecognitionWord representationsNamed Entity Recognition (NER) taskMachine learning-based approachWord representation featuresNatural language processingLearning-based approachEntity recognition taskNamed Entity RecognitionCluster-based representationJNLPBA corpusEntity recognitionBiomedical domainF-measureLanguage processingRepresentation featuresWord embeddingsRecognition taskWR algorithmDistributional representationsTaskBetter performanceAlgorithmRepresentationDifferent types
2013
Facial and Prosodic Emotion Recognition Deficits Associate with Specific Clusters of Psychotic Symptoms in Schizophrenia
Tseng H, Chen S, Liu C, Howes O, Huang Y, Hsieh M, Liu C, Shan J, Lin Y, Hwu H. Facial and Prosodic Emotion Recognition Deficits Associate with Specific Clusters of Psychotic Symptoms in Schizophrenia. PLOS ONE 2013, 8: e66571. PMID: 23818944, PMCID: PMC3688591, DOI: 10.1371/journal.pone.0066571.Peer-Reviewed Original ResearchConceptsEmotion recognition abilityCluster of psychotic symptomsPsychotic symptomsEmotion recognition taskHappy emotionHealthy participantsDysfunction of brain systemsSeverity of psychotic symptomsDeficits of emotion recognitionPresentation of psychotic symptomsDSM-IV diagnostic criteriaRecognition taskPANSS total scoreSensory modalitiesEmotion recognitionRecognition abilityEvaluation of symptomatologySeverity of clinical symptomsHappy prosodyNegative symptomsPerseveration errorsWAIS-IIIDSM-IVEmotional processingBrain systems
2010
Recognizing Medication related Entities in Hospital Discharge Summaries using Support Vector Machine.
Doan S, Xu H. Recognizing Medication related Entities in Hospital Discharge Summaries using Support Vector Machine. Proceedings - International Conference On Computational Linguistics 2010, 2010: 259-266. PMID: 26848286, PMCID: PMC4736747.Peer-Reviewed Original ResearchSupport vector machineHospital discharge summariesConditional Random FieldsDischarge summariesMedication namesRelated entitiesClinical textVector machineType of medicationNamed Entity Recognition (NER) taskEntity recognition taskRule-based systemBest F-scoreI2b2 NLP challengeTypes of featuresF-scoreI2b2 challengeNLP challengeNER systemSemantic featuresRecognition taskMachineData setsRandom fieldsBetter performance
2009
Behavioral and neural correlates of memory selection and interference resolution during a digit working memory task
Yi Y, Driesen N, Leung HC. Behavioral and neural correlates of memory selection and interference resolution during a digit working memory task. Cognitive, Affective, & Behavioral Neuroscience 2009, 9: 249-259. PMID: 19679761, PMCID: PMC2741611, DOI: 10.3758/cabn.9.3.249.Peer-Reviewed Original ResearchConceptsProactive interferenceMemory selectionNeural correlatesEffects of PILeft inferior parietal lobePrefrontal-parietal networkStrong proactive interferenceTask-relevant informationInferior parietal lobeResponse time differencesMiddle frontal gyrusPosterior parietal cortexInterference resolutionMemory taskFrontal gyrusRecognition taskRelevant digitsSelection cuesDelay intervalPrecue intervalsParietal cortexInformation processingParietal lobeTaskCorrelates
2004
Event‐related brain potentials reveal anomalies in temporal processing of faces in autism spectrum disorder
McPartland J, Dawson G, Webb SJ, Panagiotides H, Carver LJ. Event‐related brain potentials reveal anomalies in temporal processing of faces in autism spectrum disorder. Journal Of Child Psychology And Psychiatry 2004, 45: 1235-1245. PMID: 15335344, DOI: 10.1111/j.1469-7610.2004.00318.x.Peer-Reviewed Original ResearchConceptsEvent-related brain potentialsLonger N170 latenciesFace processingN170 latencyAutism spectrum disorderTypical individualsBrain potentialsNeural speedSpectrum disorderHigh-density event-related brain potentialsFace-sensitive ERP componentsImages of facesFace recognition taskRole of speedUpright facesERP componentsTemporal processingRecognition taskExhibit impairmentsBrain activityAutismFace recognitionCurrent studyProcessingFace
2003
Acute SSRI Administration Affects the Processing of Social Cues in Healthy Volunteers
Harmer C, Bhagwagar Z, Perrett D, Völlm B, Cowen P, Goodwin G. Acute SSRI Administration Affects the Processing of Social Cues in Healthy Volunteers. Neuropsychopharmacology 2003, 28: 148-152. PMID: 12496951, DOI: 10.1038/sj.npp.1300004.Peer-Reviewed Original ResearchConceptsEmotional processingFacial expressionsFacial expression recognition taskExpression recognition taskAcute SSRI administrationBasic emotionsSocial cuesEmotional intensityNeural processesSocial informationRecognition taskEarly acute effectsReduced response timeEmotional standardsSubjective experienceSocial behaviorTesting sessionsSSRI administrationAcute administrationMoodSelective serotonin reuptake inhibitorsProcessingSerotonin reuptake inhibitorsRole of serotoninHealthy female volunteers
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