2024
Lower slow wave sleep and rapid eye‐movement sleep are associated with brain atrophy of AD‐vulnerable regions
Cho G, Mecca A, Buxton O, Liu X, Miner B. Lower slow wave sleep and rapid eye‐movement sleep are associated with brain atrophy of AD‐vulnerable regions. Alzheimer's & Dementia 2024, 20: e093827. PMCID: PMC11713325, DOI: 10.1002/alz.093827.Peer-Reviewed Original ResearchInferior parietal regionsSlow wave sleepAD-vulnerable regionsAssociated with smaller volumesParietal regionsPresence of cerebral microbleedsSleep architectureAlzheimer's diseaseCerebral microbleedsIncreased risk of Alzheimer's diseaseProportion of timeRisk of Alzheimer's diseaseBaseline cognitive functionLobar cerebral microbleedsModifiable risk factorsAssociated with lower volumesAssociated with brain atrophyBaseline sleep architectureSleep architecture variablesSleep deficiencyAssociated with ADFalse discovery rateAtherosclerosis RiskAD pathogenesisEye-movement sleepLower slow wave sleep and rapid eye‐movement sleep are associated with brain atrophy of AD‐vulnerable regions
Cho G, Mecca A, Buxton O, Liu X, Miner B. Lower slow wave sleep and rapid eye‐movement sleep are associated with brain atrophy of AD‐vulnerable regions. Alzheimer's & Dementia 2024, 20: e089369. PMCID: PMC11716384, DOI: 10.1002/alz.089369.Peer-Reviewed Original ResearchInferior parietal regionsSlow wave sleepAD-vulnerable regionsAssociated with smaller volumesParietal regionsPresence of cerebral microbleedsSleep architectureAlzheimer's diseaseCerebral microbleedsIncreased risk of Alzheimer's diseaseProportion of timeRisk of Alzheimer's diseaseBaseline cognitive functionLobar cerebral microbleedsModifiable risk factorsAssociated with lower volumesAssociated with brain atrophyBaseline sleep architectureSleep architecture variablesSleep deficiencyAssociated with ADFalse discovery rateAtherosclerosis RiskAD pathogenesisEye-movement sleep
2023
Effects of epileptiform activity on discharge outcome in critically ill patients in the USA: a retrospective cross-sectional study
Parikh H, Hoffman K, Sun H, Zafar S, Ge W, Jing J, Liu L, Sun J, Struck A, Volfovsky A, Rudin C, Westover M. Effects of epileptiform activity on discharge outcome in critically ill patients in the USA: a retrospective cross-sectional study. The Lancet Digital Health 2023, 5: e495-e502. PMID: 37295971, PMCID: PMC10528143, DOI: 10.1016/s2589-7500(23)00088-2.Peer-Reviewed Original ResearchConceptsCross-sectional studyEffects of epileptiform activityGeneral hospital intensive care unitIncreased risk of disabilityIntensive care unitCross-sectional study of patientsRisk of disabilityActivity burdenCare unitEpileptiform activityAssociated with worse patient outcomesRetrospective cross-sectional studyHospital intensive care unitDischarge outcomesPoor outcomeGeneral HospitalMassachusetts General HospitalEffect sizePatient outcomesMedical feedbackProportion of timeStudy of patientsIncreased riskHypoxic-ischaemic encephalopathyCritically ill patients
2021
A comparison of two hybrid closed-loop systems in adolescents and young adults with type 1 diabetes (FLAIR): a multicentre, randomised, crossover trial
Bergenstal RM, Nimri R, Beck RW, Criego A, Laffel L, Schatz D, Battelino T, Danne T, Weinzimer SA, Sibayan J, Johnson ML, Bailey RJ, Calhoun P, Carlson A, Isganaitis E, Bello R, Albanese-O'Neill A, Dovc K, Biester T, Weyman K, Hood K, Phillip M, Group F. A comparison of two hybrid closed-loop systems in adolescents and young adults with type 1 diabetes (FLAIR): a multicentre, randomised, crossover trial. The Lancet 2021, 397: 208-219. PMID: 33453783, PMCID: PMC9194961, DOI: 10.1016/s0140-6736(20)32514-9.Peer-Reviewed Original ResearchConceptsAdvanced hybrid closed-loop systemType 1 diabetesHybrid closed-loop systemMiniMed 670G systemGlucose levelsCrossover trialYoung adultsMultiple daily insulin injectionsSevere hypoglycaemic eventsDaily insulin injectionsComputer-generated sequencePermuted block designContinuous glucose monitoringBaseline HbACoprimary outcomesEndocrinology practiceHypoglycaemic eventsWashout periodHemoglobin levelsKidney diseaseMean ageInsulin injectionsProportion of timeContinuous glucose monitorImpaired awareness
2013
Time-motion analysis of emergency radiologists and emergency physicians at an urban academic medical center
Perry WM, Lee CI, Steers WN, Post LA, Forman HP. Time-motion analysis of emergency radiologists and emergency physicians at an urban academic medical center. Emergency Radiology 2013, 20: 409-416. PMID: 23636334, DOI: 10.1007/s10140-013-1129-5.Peer-Reviewed Original ResearchConceptsEmergency physiciansPhysical findingsEmergency radiologistsPatient historyMedical CenterUrban academic Level IUrban academic medical centerAcademic Level IPatients' physical findingsAcademic medical centerAcute patientsPatient evaluationProportion of timeDiagnostic evaluationPhysician counterpartsLevel IMultivariate analysisPhysiciansCombined proportionRadiologistsTime-motion analysisLarge proportionProportionFindingsSpecialties
1991
Fetal movement during labor
Reddy U, Paine L, Gegor C, Johnson M, Johnson T. Fetal movement during labor. American Journal Of Obstetrics And Gynecology 1991, 165: 1073-1076. PMID: 1951516, DOI: 10.1016/0002-9378(91)90473-5.Peer-Reviewed Original Research
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