2018
Clinical Outcomes of Plavix and Generic Clopidogrel for Patients Hospitalized With an Acute Coronary Syndrome
Ko DT, Krumholz HM, Tu JV, Austin PC, Stukel TA, Koh M, Chong A, de Melo JF, Jackevicius CA. Clinical Outcomes of Plavix and Generic Clopidogrel for Patients Hospitalized With an Acute Coronary Syndrome. Circulation Cardiovascular Quality And Outcomes 2018, 11: e004194. PMID: 29535091, DOI: 10.1161/circoutcomes.117.004194.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAged, 80 and overClopidogrelCost SavingsCost-Benefit AnalysisDatabases, FactualDrug CostsDrug SubstitutionDrugs, GenericFemaleHemorrhageHumansMaleOntarioPatient AdmissionPatient ReadmissionPlatelet Aggregation InhibitorsPurinergic P2Y Receptor AntagonistsRecurrenceRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeConceptsAcute coronary syndromeGeneric clopidogrelClinical outcomesCoronary syndromePrimary outcomeRecurrent acute coronary syndromeSubstantial healthcare cost savingsPopulation-based observational studyPropensity-weighted cohortsComposite of deathTransient ischemic attackComposite end pointEffect of clopidogrelElevation myocardial infarctionHealthcare cost savingsCox proportional hazardsRate of deathIschemic attackACS hospitalizationCause readmissionBaseline characteristicsHospital dischargeRecurrent hospitalizationsMean ageMyocardial infarction
2014
Patterns of chemotherapy, toxicity, and short-term outcomes for older women receiving adjuvant trastuzumab-based therapy
Freedman RA, Vaz-Luis I, Barry WT, Lii H, Lin NU, Winer EP, Keating NL. Patterns of chemotherapy, toxicity, and short-term outcomes for older women receiving adjuvant trastuzumab-based therapy. Breast Cancer Research And Treatment 2014, 145: 491-501. PMID: 24756187, DOI: 10.1007/s10549-014-2968-9.Peer-Reviewed Original ResearchConceptsNon-standard chemotherapyTrastuzumab-based therapyAdjuvant trastuzumab-based therapyOlder womenChemotherapy receiptHazard ratioBreast cancerHER2-positive breast cancerPattern of chemotherapyPropensity-weighted cohortsToxicity-related hospitalizationAdjusted hazard ratioTreatment-related toxicityMonths of chemotherapyShort-term outcomesMultivariable logistic regressionPopulation-based cohortPropensity score adjustmentAssociation of ageShort-term survivalComorbidity scoreOlder patientsTreatment toxicityWorse survivalHospital events
2012
Effect of Massachusetts health insurance reform on mammography use and breast cancer stage at diagnosis
Keating NL, Kouri EM, He Y, West DW, Winer EP. Effect of Massachusetts health insurance reform on mammography use and breast cancer stage at diagnosis. Cancer 2012, 119: 250-258. PMID: 22833148, DOI: 10.1002/cncr.27757.Peer-Reviewed Original ResearchConceptsPropensity-weighted cohortsMammography ratesStage I breast cancerBehavioral Risk Factor Surveillance System surveyInsurance expansionStage I cancerI breast cancerBreast cancer stageCancer registry dataUse of mammographyRate of diagnosisRates of mammographyPropensity score analysisRates of uninsuranceHigher uninsurance ratesBreast cancer diagnosisHealth insurance expansionsI cancerCancer stageBreast cancerMammography useRegistry dataCalifornia womenMassachusetts womenDiagnosis
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