2024
Childhood maltreatment is associated with lower exploration and disrupted prefrontal activity and connectivity during reward learning in volatile environments
Armbruster‐Genç D, Neil L, Valton V, Phillips H, Rankin G, Sharp M, Rapley J, Viding E, Roiser J, McCrory E. Childhood maltreatment is associated with lower exploration and disrupted prefrontal activity and connectivity during reward learning in volatile environments. Journal Of Child Psychology And Psychiatry 2024, 66: 846-856. PMID: 39665511, PMCID: PMC12062857, DOI: 10.1111/jcpp.14095.Peer-Reviewed Original ResearchFunctional magnetic resonance imagingReward learningOrbitofrontal cortexChildhood maltreatmentProbabilistic reinforcement learning taskDocumented history of maltreatmentAtypical reward processingOrbitofrontal cortex connectivityNon-maltreated individualsLower exploratory behaviorMid-cingulate cortexDisrupt neural processingHistory of maltreatmentImpact of maltreatmentReinforcement learning taskPrefrontal activationReward processingReward contingenciesNeural indicesOutcome deliveryNeural signalsLatent vulnerabilityBehavioral measuresInternalising symptomsOutcome processing
2019
Prefrontal activation related to spontaneous creativity with rock music improvisation: A functional near-infrared spectroscopy study
Tachibana A, Noah J, Ono Y, Taguchi D, Ueda S. Prefrontal activation related to spontaneous creativity with rock music improvisation: A functional near-infrared spectroscopy study. Scientific Reports 2019, 9: 16044. PMID: 31690744, PMCID: PMC6831592, DOI: 10.1038/s41598-019-52348-6.Peer-Reviewed Original ResearchConceptsDorsolateral prefrontal cortexLeft dorsolateral prefrontal cortexPrefrontal cortexNeural activitySubjective feelingsExecutive control networkMedial frontal lobePrefrontal activationExpert musiciansNeural responsesRange of skillsSpontaneous creativityBrain activityDefault modeMusic improvisationDetermine similarityFormulaic sequencesNeural modulationControl networkFrontal lobeSimilar modulationImprovisational performanceImprovisationFeelingsSkills
2015
Reduced Prefrontal Activation in Pediatric Patients With Obsessive-Compulsive Disorder During Verbal Episodic Memory Encoding
Batistuzzo M, Balardin J, da Graça Morais Martin M, Hoexter M, Bernardes E, Borcato S, de Marco e Souza M, Querido C, Morais R, de Alvarenga P, Lopes A, Shavitt R, Savage C, Amaro E, Miguel E, Polanczyk G, Miotto E. Reduced Prefrontal Activation in Pediatric Patients With Obsessive-Compulsive Disorder During Verbal Episodic Memory Encoding. Journal Of The American Academy Of Child & Adolescent Psychiatry 2015, 54: 849-858. PMID: 26407495, DOI: 10.1016/j.jaac.2015.06.020.Peer-Reviewed Original ResearchConceptsVerbal episodic memoryObsessive-compulsive disorderEpisodic memoryOrbitofrontal cortexPrefrontal cortexSemantic clusteringFunctional magnetic resonance imagingDorsomedial prefrontal cortexAltered brain activationDifferent neural mechanismsPathophysiology of OCDUnrelated wordsPrefrontal activationBrain activationWord listsExecutive dysfunctionNeural mechanismsTotal wordsCompulsive Scale scoresYale-Brown Obsessive Compulsive Scale scoresStrategy scoresStrategy applicationMemoryCortexKey regions
2012
Guanfacine effects on stress, drug craving and prefrontal activation in cocaine dependent individuals: preliminary findings
Fox HC, Seo D, Tuit K, Hansen J, Kimmerling A, Morgan PT, Sinha R. Guanfacine effects on stress, drug craving and prefrontal activation in cocaine dependent individuals: preliminary findings. Journal Of Psychopharmacology 2012, 26: 958-972. PMID: 22234929, PMCID: PMC3694403, DOI: 10.1177/0269881111430746.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic alpha-2 Receptor AgonistsAdultCocaine-Related DisordersCombined Modality TherapyConnecticutDiagnostic and Statistical Manual of Mental DisordersDose-Response Relationship, DrugDouble-Blind MethodFemaleGuanfacineHumansImagery, PsychotherapyMagnetic Resonance ImagingMaleMiddle AgedNeuronsPilot ProjectsPrefrontal CortexStress, PsychologicalSubstance Withdrawal SyndromeConceptsCocaine-dependent individualsPrefrontal activityDrug cravingFunctional magnetic resonance imaging sessionDrug cue-induced cravingTreatment-seeking cocaine dependent individualsCue-induced drug cravingDependent individualsMagnetic resonance imaging sessionLateral prefrontal activityCue-induced cravingDrug cue exposureGuanfacine's effectsDrug cuesSubjective cravingImagery conditionPrefrontal activationCue exposurePhysiological arousalCognitive challengesBrain responsesAgonist guanfacineNicotine cravingGuanfacine groupCraving
2009
A neural measure of behavioral engagement: Task-residual low-frequency blood oxygenation level-dependent activity in the precuneus
Zhang S, Li CS. A neural measure of behavioral engagement: Task-residual low-frequency blood oxygenation level-dependent activity in the precuneus. NeuroImage 2009, 49: 1911-1918. PMID: 19761851, PMCID: PMC2791356, DOI: 10.1016/j.neuroimage.2009.09.004.Peer-Reviewed Original ResearchConceptsBlood oxygenation level-dependent activityRegional brain activationLevel-dependent activityTask engagementNeural measuresNeural processesBrain activationPosterior cingulate cortexAttentional monitoringResponse inhibitionHuman cognitionPrefrontal activationSignal taskGreater activationBOLD activityBehavioral engagementCingulate cortexPrecuneusBrain regionsLow-frequency fluctuationsFractional amplitudeBrain imagingSeed regionIndependent component analysisEngagement
1998
Assessment of prefrontal activation by infrequent visual targets and non-target novel stimuli in schizophrenia: A functional MRI study
Belger A, Kirino E, McCarthy G, Gore J, Krystal J. Assessment of prefrontal activation by infrequent visual targets and non-target novel stimuli in schizophrenia: A functional MRI study. Schizophrenia Research 1998, 29: 106. DOI: 10.1016/s0920-9964(97)88567-2.Peer-Reviewed Original Research
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