2025
Migraines as a Risk Factor for Many 90-Day Postoperative Complications Following Single-Level Anterior Cervical Diskectomy and Fusion
Katsnelson B, Jonnalagadda A, Rancu A, Winter A, Grauer J. Migraines as a Risk Factor for Many 90-Day Postoperative Complications Following Single-Level Anterior Cervical Diskectomy and Fusion. JAAOS Global Research And Reviews 2025, 9: e25.00060. PMID: 40828986, PMCID: PMC12367040, DOI: 10.5435/jaaosglobal-d-25-00060.Peer-Reviewed Original ResearchConceptsHistory of migraineCervical spine surgeryAnterior cervical diskectomyPostoperative adverse outcomesAdverse outcomesACDF patientsACDF surgerySpine surgeryCervical diskectomyAdverse eventsSingle-level anterior cervical diskectomyEmergency department visitsPotential predisposing risk factorsRisk factorsKaplan-Meier survival curvesAssociated with adverse outcomesMultivariate logistic regression analysisSingle-level ACDFLog-rank testPostoperative adverse eventsLogistic regression analysisDepartment visitsSpine infectionACDF proceduresPostoperative complicationsNoninstrumented Posterolateral Lumbar Fusions Continue to Fade Relative to Instrumented Posterolateral Approaches for Lumbar Degenerative Spondylolisthesis Over the Past Decade
Lee A, Day W, Lavu S, Pappajohn A, Gouzoulis M, Grauer J. Noninstrumented Posterolateral Lumbar Fusions Continue to Fade Relative to Instrumented Posterolateral Approaches for Lumbar Degenerative Spondylolisthesis Over the Past Decade. JAAOS Global Research And Reviews 2025, 9: e25.00192. PMID: 40828985, PMCID: PMC12366972, DOI: 10.5435/jaaosglobal-d-25-00192.Peer-Reviewed Original ResearchConceptsRevision surgery ratesPosterolateral lumbar fusionLumbar degenerative spondylolisthesisSurgery ratesDegenerative spondylolisthesis patientsAdverse eventsLumbar fusionPatient characteristicsDegenerative spondylolisthesisSpondylolisthesis patientsSingle-level posterolateral lumbar fusionNonclinical patient characteristicsKaplan-Meier survival analysisLog-rank testPostoperative adverse outcomesPostoperative adverse eventsMultivariate logistic regressionElixhauser Comorbidity IndexPatient ageAggregate adverse eventsNoninstrumented fusionsOsteoporotic patientsNinety-dayUnivariate analysisAdverse outcomesCefazolin Alone Versus Cefazolin With Tobramycin or Gentamicin as Intraoperative Antibiotic Prophylaxis for Total Joint Arthroplasty
Dhodapkar M, Halperin S, Radford Z, Rubin L, Grauer J, Li M. Cefazolin Alone Versus Cefazolin With Tobramycin or Gentamicin as Intraoperative Antibiotic Prophylaxis for Total Joint Arthroplasty. Arthroplasty Today 2025, 31: 101613. PMID: 39911247, PMCID: PMC11794179, DOI: 10.1016/j.artd.2024.101613.Peer-Reviewed Original ResearchFive-year implant survivalTotal knee arthroplastyElixhauser Comorbidity IndexProphylactic cefazolinImplant survivalAdverse outcomesComorbidity indexTotal hip arthroplastyAntibiotic prophylaxis regimensIntraoperative antibiotic prophylaxisStandard prophylactic antibioticsKaplan-Meier analysisLog-rank testPerioperative adverse outcomesPostoperative adverse outcomesProsthetic joint infectionMultivariate logistic regressionAntibiotic prophylaxisProphylaxis regimensTotal knee arthroplasty patientsProphylactic antibioticsSSI ratesComplication of total knee arthroplastyJoint infectionCefazolin
2024
The prognostic utility of galectin-3 in patients undergoing cardiac surgery: a scoping review
Shah A, Ding Y, Walji D, Rabinovich G, Pelletier M, El-Diasty M. The prognostic utility of galectin-3 in patients undergoing cardiac surgery: a scoping review. Biomarkers 2024, 29: 485-493. PMID: 39422445, DOI: 10.1080/1354750x.2024.2415073.Peer-Reviewed Original ResearchConceptsAssociated with acute kidney injuryPostoperative atrial fibrillationGal-3 levelsLeft ventricular reverse remodelingCardiac surgeryAdverse outcomesGal-3Clinical risk prediction scorePreoperative plasma levelsVentricular reverse remodelingEuroSCORE II modelPlasma Gal-3 levelsPostoperative adverse outcomesAcute kidney injuryGalectin-3Group of patientsPredicting Adverse OutcomesRisk prediction scorePostoperative morbidityReverse remodelingPostoperative mortalityElectronic database searchPrognostic utilityAdult patientsKidney injuryCefazolin Alone Versus Cefazolin with Tobramycin or Gentamicin as Intraoperative Antibiotic Prophylaxis for Single-Level Posterior Lumbar Fusion
Dhodapkar M, Jeong S, Halperin S, Rubio D, Li M, Grauer J. Cefazolin Alone Versus Cefazolin with Tobramycin or Gentamicin as Intraoperative Antibiotic Prophylaxis for Single-Level Posterior Lumbar Fusion. JAAOS Global Research And Reviews 2024, 8: e24.00082. PMCID: PMC11068128, DOI: 10.5435/jaaosglobal-d-24-00082.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSurgical site infectionElixhauser Comorbidity IndexLumbar fusionAntibiotic prophylaxisAdverse outcomesAntibiotic prophylaxis regimenAntibiotic prophylaxis regimensIntraoperative antibiotic prophylaxisRevision ratePerioperative antibiotic prophylaxisPostoperative adverse outcomesPosterior lumbar fusion patientsMultivariate logistic regressionProphylaxis regimensProphylaxis regimenPatient ageSite infectionUnivariate analysisCefazolinComorbidity indexMultivariate analysisAntibiotic subgroupsTraumatic diagnoses
2021
Predictors and Sequelae of Postoperative Delirium in a Geriatric Patient Population With Hip Fracture
Haynes MS, Alder KD, Toombs C, Amakiri IC, Rubin LE, Grauer JN. Predictors and Sequelae of Postoperative Delirium in a Geriatric Patient Population With Hip Fracture. JAAOS Global Research And Reviews 2021, 5: e20.00221. PMID: 33989253, PMCID: PMC8133215, DOI: 10.5435/jaaosglobal-d-20-00221.Peer-Reviewed Original ResearchConceptsHip fracture populationPostoperative deliriumPreoperative dementiaHip fractureGeriatric hip fracture populationDependent functional statusFracture populationAdverse postoperative outcomesHigher American SocietyIndependent risk factorPostoperative adverse outcomesGeriatric patient populationNongeneral anesthesiaPreoperative diabetesPostoperative outcomesIndependent predictorsMale sexAdverse outcomesPatient populationFunctional statusRevision surgeryRisk factorsDeliriumHigher oddsRisk subpopulations
2020
Perioperative Outcomes of Hemiarthroplasty Versus Total Hip Arthroplasty for Geriatric Hip Fracture: The Importance of Studying Matched Populations
Haynes MS, Ondeck NT, Ottesen TD, Malpani R, Rubin LE, Grauer JN. Perioperative Outcomes of Hemiarthroplasty Versus Total Hip Arthroplasty for Geriatric Hip Fracture: The Importance of Studying Matched Populations. The Journal Of Arthroplasty 2020, 35: 3188-3194. PMID: 32654940, DOI: 10.1016/j.arth.2020.06.015.Peer-Reviewed Original ResearchConceptsTotal hip arthroplastyHip fractureAdverse eventsPropensity matchingBlood transfusionHip arthroplastyNational Surgical Quality Improvement databaseGeriatric femoral neck fracturesGreater readmission ratesGeriatric hip fracturesLower transfusion rateMajor adverse eventsMinor adverse eventsPostoperative adverse outcomesFemoral neck fracturesQuality improvement databaseRetrospective comparative studyMultivariate logistic regressionTransfusion ratePerioperative outcomesReadmission ratesSelect patientsTHA groupGeriatric patientsNeck fracturesVenous thromboembolism in children undergoing surgery: incidence, risk factors and related adverse events
Mets E, McLynn R, Grauer J. Venous thromboembolism in children undergoing surgery: incidence, risk factors and related adverse events. World Journal Of Pediatric Surgery 2020, 3: e000084. PMID: 36474866, PMCID: PMC9716836, DOI: 10.1136/wjps-2019-000084.Peer-Reviewed Original ResearchPostoperative venous thromboembolismVenous thromboembolismAdverse eventsSurgical factorsRisk factorsNational Surgical Quality Improvement Project Pediatric databaseSubsequent venous thromboembolismPerioperative adverse eventsPostoperative adverse outcomesRelated adverse eventsRetrospective cohort analysisLonger operative timePediatric surgical patientsPediatric surgical populationPreventable adverse eventsNon-elective surgeryAnesthesiologists classSurgical populationVTE eventsSurgical patientsPediatric patientsTrauma patientsOperative timeAdverse outcomesCardiothoracic surgery
2019
Abnormally High, as Well as Low, Preoperative Platelet Counts Correlate With Adverse Outcomes and Readmissions After Elective Total Knee Arthroplasty
Malpani R, Haynes MS, Clark MG, Galivanche AR, Bovonratwet P, Grauer JN. Abnormally High, as Well as Low, Preoperative Platelet Counts Correlate With Adverse Outcomes and Readmissions After Elective Total Knee Arthroplasty. The Journal Of Arthroplasty 2019, 34: 1670-1676. PMID: 31072745, DOI: 10.1016/j.arth.2019.04.012.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAnemiaArthroplasty, Replacement, KneeDatabases, FactualDiabetes ComplicationsElective Surgical ProceduresFemaleHumansLength of StayMaleMiddle AgedPatient ReadmissionPlatelet CountPostoperative ComplicationsPostoperative PeriodPreoperative PeriodRetrospective StudiesThrombocytopeniaThrombocytosisTreatment OutcomeUnited StatesYoung AdultConceptsTotal knee arthroplastyElective total knee arthroplastyMinor adverse eventsPreoperative platelet countAbnormal platelet countLow platelet countPlatelet countHigher platelet countsAdverse eventsPostoperative complicationsTKA patientsAdverse outcomesKnee arthroplastyNational Surgical Quality Improvement Program databaseElective primary total knee arthroplastyMultivariate analysisQuality Improvement Program databasePrimary total knee arthroplastyMulticenter patient populationImprovement Program databasePostoperative adverse outcomesPlatelet count thresholdRetrospective comparative studyNormal platelet countLarger patient sample size
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