2012
Quantitative histological‐hemodynamic correlations in cirrhosis
Sethasine S, Jain D, Groszmann RJ, Garcia‐Tsao G. Quantitative histological‐hemodynamic correlations in cirrhosis. Hepatology 2012, 55: 1146-1153. PMID: 22109744, PMCID: PMC3721182, DOI: 10.1002/hep.24805.Peer-Reviewed Original ResearchConceptsSignificant portal hypertensionPortal hypertensionFibrosis areaLiver biopsyCirrhotic nodulesNodule sizeHVPG measurementPortal pressureIndependent predictorsSeptal thicknessFibrous septaBiopsyPathophysiological implicationsCirrhosisHVPGPatientsSemiquantitative analysisNodulesOnly parameterHypertensionNumber of nodules
2011
Chapter 39 Vitamin D Relevance in Reproductive Biology and Pathophysiological Implications in Reproductive Dysfunction
Pal L, Taylor H. Chapter 39 Vitamin D Relevance in Reproductive Biology and Pathophysiological Implications in Reproductive Dysfunction. 2011, 695-705. DOI: 10.1016/b978-0-12-381978-9.10039-3.BooksVitamin D deficiencyVitamin DD deficiencyInsulin resistancePrevention of endometriosisVitamin D inadequacyAutoimmune disordersPathophysiological mechanismsCardiovascular diseaseReproductive dysfunctionReproductive compromiseDisease processPathophysiological implicationsExperimental modelRepletion strategiesKey moleculesFemale fertilityReproductive physiologyAccessible optionDeficiencyCurrent understandingEndometriosisObesityPregnancyDysfunction
2000
Brain regional development of the activity of α-ketoglutarate dehydrogenase complex in the rat
Buerstatte C, Behar K, Novotny E, Lai J. Brain regional development of the activity of α-ketoglutarate dehydrogenase complex in the rat. Brain Research 2000, 125: 139-145. PMID: 11154769, DOI: 10.1016/s0165-3806(00)00134-6.Peer-Reviewed Original ResearchConceptsAdult levelsKGDHC activityCerebral cortexOlfactory bulbPostnatal day 2Age-dependent increaseGlucose oxidative metabolismAlpha-ketoglutarate dehydrogenase complex activityRat brainDay 2Pathophysiological implicationsPostnatal developmentDistinct region-specific patternsNeurotransmitter synthesisRegion-specific patternsOxidative metabolismDehydrogenase complex activityHippocampusStriatumEnergy metabolismCerebellumP30TCA cycle fluxP17P10
1993
Molecular dissection of the myelinated axon
Waxman S, Ritchie J. Molecular dissection of the myelinated axon. Annals Of Neurology 1993, 33: 121-136. PMID: 7679565, DOI: 10.1002/ana.410330202.Peer-Reviewed Original ResearchConceptsMyelinated axonsInternodal axon membraneDemyelinated axonsCentral nervous system white matterNervous system white matterRestoration of conductionImportant therapeutic approachSchwann cell processesWhite matter axonsInflux of Ca2Important pathophysiological implicationsGlial cell processesAction potential conductionAxonal excitabilityGlial cellsAnoxic injuryMyelinated fibersTherapeutic approachesAstrocyte processesCell processesPathophysiological implicationsRepetitive firingWhite matterNeurological disordersAction potentials
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