2025
Disparities in the association of ambient air pollution with childhood asthma incidence in the ECHO consortium: A US-wide multi-cohort study
Wang V, Habre R, Ryan P, Coull B, Datta S, Luttmann-Gibson H, Blossom J, Just A, Schwartz J, Yanosky J, Aris I, Chandran A, Kress A, Breton C, Farzan S, Camargo C, Liang D, Ferrera A, Peterson A, Kerver J, Karr C, Leve L, Dabelea D, Karagas M, Bennett D, Nkoy F, Aschner J, O’Shea T, Lothrop N, McEvoy C, Knapp E, Schuh H, Miller R, Gold D, Zanobetti A, Smith P, Newby L, Adair L, Jacobson L, Catellier D, McGrath M, Douglas C, Duggal P, Knapp E, Kress A, Blackwell C, Mansolf M, Lai J, Ho E, Cella D, Gershon R, Macy M, Das S, Freedman J, Mallal S, McLean J, Shah R, Shilts M, Alshawabkeh A, Cordero J, Meeker J, Trasande L, Camargo C, Hasegawa K, Zhu Z, Sullivan A, Dabelea D, Perng W, Bekelman T, Wilkening G, Magzamen S, Moore B, Starling A, Rinehart D, Mitchell D, D’Sa V, Deoni S, Mueller H, Duarte C, Monk C, Canino G, Posner J, Murray T, Lugo-Candelas C, Dunlop A, Brennan P, Hockett C, Elliott A, Ferrara A, Croen L, Hedderson M, Ainsworth J, Bacharier L, Bendixsen C, Gern J, Gold D, Hartert T, Jackson D, Johnson C, Joseph C, Kattan M, Hershey G, Lemanske R, Lynch S, Miller R, O’Connor G, Ober C, Ownby D, Rivera-Spoljaric K, Ryan P, Seroogy C, Singh A, Wood R, Zoratti E, Habre R, Farzan S, Gilliland F, Hertz-Picciotto I, Bennett D, Schweitzer J, Schmidt R, LaSalle J, Hipwell A, Keenan K, Karr C, Bush N, LeWinn K, Sathyanarayana S, Zhao Q, Tylavsky F, Carroll K, Loftus C, Leve L, Ganiban J, Neiderhiser J, Weiss S, Litonjua A, McEvoy C, Spindel E, Tepper R, Newschaffer C, Lyall K, Volk H, Landa R, Ozonoff S, Piven J, Hazlett H, Pandey J, Schultz R, Dager S, Botteron K, Messinger D, Stone W, Ames J, O’Connor T, Miller R, Oken E, Hacker M, James-Todd T, O’Shea T, Fry R, Frazier J, Singh R, Rollins C, Montgomery A, Vaidya R, Joseph R, Washburn L, Gogcu S, Bear K, Rollins J, Hooper S, Taylor G, Jackson W, Thompson A, Daniels J, Hernandez M, Lu K, Msall M, Lenski M, Obeid R, Pastyrnak S, Jensen E, Sakai C, Santos H, Kerver J, Paneth N, Barone C, Elliott M, Ruden D, Fussman C, Herbstman J, Margolis A, Schantz S, Geiger S, Aguiar A, Tabb K, Strakovsky R, Woodruff T, Morello-Frosch R, Padula A, Stanford J, Porucznik C, Giardino A, Wright R, Wright R, Collett B, Baumann-Blackmore N, Gangnon R, Jackson D, McKennan C, Wilson J, Altman M, Aschner J, Stroustrup A, Merhar S, Moore P, Pryhuber G, Hudak M, Lyndaker A, Lampland A, Rochelson B, Jan S, Blitz M, Katzow M, Brown Z, Chiuzan C, Rafael T, Lewis D, Meirowitz N, Poindexter B, Gebretsadik T, Osmundson S, Straughen J, Eapen A, Cassidy-Bushrow A, Wegienka G, Sitarik A, Woodcroft K, Urquhart A, Levin A, Johnson-Hooper T, Davidson B, Ma T, Barrett E, Blaser M, Dominguez-Bello M, Horton D, Jimenez M, Rosen T, Palomares K, Avalos L, Zhu Y, Hunt K, Newman R, Bloom M, Alkis M, Roberts J, Mumford S, Burris H, DeMauro S, Yee L, Hamvas A, Olidipo A, Haddad A, Eiland L, Spillane N, Suri K, Fisher S, Goldstein J, Mithal L, DeRegnier R, Maitre N, Nguyen R, JaKa M, Sidebottom A, Paidas M, Potter J, Ruby N, Duthely L, Jayakumar A, Young K, Maldonado I, Miller M, Slaughter J, Keim S, Lynch C, Venkatesh K, Whitworth K, Symanski E, Northrup T, Mendez-Figueroa H, Mosquera R, Karagas M, Madan J, MacKenzie D, Lewis J, Rennie B, Leventhal B, Kim Y, Bishop S, Nozadi S, Luo L, Lester B, Marsit C, Everson T, Loncar C, McGowan E, Sheinkopf S, Carter B, Check J, Helderman J, Neal C, Smith L. Disparities in the association of ambient air pollution with childhood asthma incidence in the ECHO consortium: A US-wide multi-cohort study. Environmental Epidemiology 2025, 9: e398. PMID: 40520482, PMCID: PMC12160752, DOI: 10.1097/ee9.0000000000000398.Peer-Reviewed Original ResearchExposure to fine particulate matterIncident asthmaAsthma riskRisk of incident asthmaAssociation of ambient air pollutionProportion of Black residentsChild health outcomesChildhood asthma incidenceChildhood asthma riskInterquartile range increaseFine particulate matterAmbient air pollutionNitrogen dioxideHealth outcomesSociodemographic disparitiesAsthma incidenceAsthma diagnosisLack of participant diversityMulti-cohort studyResidential historyRange increaseParticipant diversitySociodemographic featuresBlack residentsTime trendsShort-term exposure to ambient nitrogen dioxide and fine particulate matter and cause-specific mortality: A causal modeling approach in four regions
Marb A, Ma Y, Nobile F, Dubrow R, Kinney P, Stafoggia M, Chen K, Peters A, Breitner S. Short-term exposure to ambient nitrogen dioxide and fine particulate matter and cause-specific mortality: A causal modeling approach in four regions. Environmental Pollution 2025, 372: 126059. PMID: 40089139, DOI: 10.1016/j.envpol.2025.126059.Peer-Reviewed Original ResearchParticulate matterAir pollutionDaily NO<sub>2</sub> anShort-term air pollution exposureNitrogen dioxideDaily air pollution dataExposure to NO<sub>2</sub>Effects of air pollutionShort-term exposure to NO<sub>2</sub> anFine particulate matterTwo-pollutant modelsExposure to ambient nitrogen dioxideAmbient air pollutionAmbient particulate matterAir pollution dataAir pollution exposureCause-specific mortality ratesAmbient nitrogen dioxideRural populationCause-specific mortalityRespiratory mortality ratesMortality rateCause-specific deathCardiovascular mortality ratesPollution exposureEffect of Air Pollution Reductions on Mortality During the COVID-19 Lockdowns in Early 2020.
Chen K, Ma Y, Marb A, Nobile F, Dubrow R, Stafoggia M, Breitner S, Kinney P. Effect of Air Pollution Reductions on Mortality During the COVID-19 Lockdowns in Early 2020. Research Report 2025, 2025: 1-47. PMID: 40551404, PMCID: PMC12185919.Peer-Reviewed Original ResearchConceptsAir pollution changesAir pollutionPollution changesShort-term exposure to PM<sub>2.5</sub>Air qualityExposure to PM<sub>2.5</sub>Natural-causeMeteorological normalization techniqueFine particulate matterDaily air pollutionImprove air qualityAir pollutant emissionsAir pollution reductionEmission control strategiesSouthern ItalyQuantify changesAir pollution-mortality relationshipPollution-mortality relationshipCOVID-19 lockdownShort-term exposureNOParticulate matterMeteorological impactsNitrogen dioxidePollution reduction
2024
The effects of genetic and modifiable risk factors on brain regions vulnerable to ageing and disease
Manuello J, Min J, McCarthy P, Alfaro-Almagro F, Lee S, Smith S, Elliott L, Winkler A, Douaud G. The effects of genetic and modifiable risk factors on brain regions vulnerable to ageing and disease. Nature Communications 2024, 15: 2576. PMID: 38538590, PMCID: PMC10973379, DOI: 10.1038/s41467-024-46344-2.Peer-Reviewed Original ResearchConceptsModifiable risk factorsRisk factorsBrain networksUK Biobank participantsTraffic-related air pollutionAlcohol intake frequencyBrain regionsGenome-wide associationBiobank participantsHigher-order brain regionsIntake frequencyXg blood groupEffects of ageCardiovascular deathGenetic influencesUnique contributionsNitrogen dioxideSchizophreniaBrainAgeAir pollutionAlzheimer's diseaseParkinson's diseaseSexAssociationShort-Term Exposure to Fine Particulate Matter and Nitrogen Dioxide and Mortality in 4 Countries
Ma Y, Nobile F, Marb A, Dubrow R, Stafoggia M, Breitner S, Kinney P, Chen K. Short-Term Exposure to Fine Particulate Matter and Nitrogen Dioxide and Mortality in 4 Countries. JAMA Network Open 2024, 7: e2354607. PMID: 38427355, PMCID: PMC10907920, DOI: 10.1001/jamanetworkopen.2023.54607.Peer-Reviewed Original ResearchConceptsShort-term exposure to air pollutionExposure to air pollutionFine particulate matterCross-sectional studyAir pollutionFixed-effects modelParticulate matterShort-term exposure to PM2.5Short-term exposure to fine particulate matterNO2 concentrationsExposure to fine particulate matterMortality rateNitrogen dioxideSignificant effect modificationDaily PM2.5 concentrationsTime-varying confoundersExposure to PM2.5Health outcomesEstimate associationsMortality dataEffect modificationPM2.5 concentrationsMain OutcomesDay-to-dayCentral-southern Italy
2023
Joint effect of heat and air pollution on mortality in 620 cities of 36 countries
Stafoggia M, Michelozzi P, Schneider A, Armstrong B, Scortichini M, Rai M, Achilleos S, Alahmad B, Analitis A, Åström C, Bell M, Calleja N, Carlsen H, Carrasco G, Cauchi J, Coelho M, Correa P, Diaz M, Entezari A, Forsberg B, Garland R, Guo Y, Guo Y, Hashizume M, Holobaca I, Íñiguez C, Jaakkola J, Kan H, Katsouyanni K, Kim H, Kyselý J, Lavigne E, Lee W, Li S, Maasikmets M, Madureira J, Mayvaneh F, Ng C, Nunes B, Orru H, Ortega N, Osorio S, Palomares A, Pan S, Pascal M, Ragettli M, Rao S, Raz R, Roye D, Ryti N, Saldiva P, Samoli E, Schwartz J, Scovronick N, Sera F, Tobias A, Tong S, Valencia C, Vicedo-Cabrera A, Urban A, Gasparrini A, Breitner S, Donato F. Joint effect of heat and air pollution on mortality in 620 cities of 36 countries. Environment International 2023, 181: 108258. PMID: 37837748, PMCID: PMC10702017, DOI: 10.1016/j.envint.2023.108258.Peer-Reviewed Original ResearchConceptsAmbient air pollutionAir pollutionDaily O<sub>3</sub> concentrations, dDaily PM<sub>10</sub>Over-dispersed Poisson regression modelCity-specific dataNOParticulate matterAir temperaturePollutionNitrogen dioxideDaily mortalityMortality incrementWarmer monthsEvidence of effect modificationGlobal datasetEffect modification resultsMortality estimatesMultilevel random-effects meta-analysisRandom-effects meta-analysisPoisson regression modelsMean temperatureJoint associationsDaily air temperatureEffect modification
2022
Hourly Air Pollutants and Acute Coronary Syndrome Onset in 1.29 Million Patients
Chen R, Jiang Y, Hu J, Chen H, Li H, Meng X, Ji J, Gao Y, Wang W, Liu C, Fang W, Yan H, Chen J, Wang W, Xiang D, Su X, Yu B, Wang Y, Xu Y, Wang L, Li C, Chen Y, Bell M, Cohen A, Ge J, Huo Y, Kan H. Hourly Air Pollutants and Acute Coronary Syndrome Onset in 1.29 Million Patients. Circulation 2022, 145: 1749-1760. PMID: 35450432, DOI: 10.1161/circulationaha.121.057179.Peer-Reviewed Original ResearchConceptsAir pollutionParticulate matterAir pollutants PM<sub>2.5</sub>, PConcentrations of PM<sub>2.5</sub>Short-term exposure to ambient air pollutionWorld Health Organization air quality guidelinesHourly concentrations of fine particulate matterConcentrations of fine particulate matterExposure to ambient air pollutionAir quality guidelinesCoarse particulate matterFine particulate matterCriteria air pollutantsAmbient air pollutionHourly air pollutionInterquartile range increaseQuality guidelinesHourly concentrationsAcute coronary syndromeCase-crossover studySORange increaseNitrogen dioxidePollutionSulfur dioxide
2021
The influence of dietary intake of omega-3 polyunsaturated fatty acids on the association between short-term exposure to ambient nitrogen dioxide and respiratory and cardiovascular outcomes among healthy adults
Chen H, Zhang S, Shen W, Salazar C, Schneider A, Wyatt L, Rappold A, Diaz-Sanchez D, Devlin R, Samet J, Tong H. The influence of dietary intake of omega-3 polyunsaturated fatty acids on the association between short-term exposure to ambient nitrogen dioxide and respiratory and cardiovascular outcomes among healthy adults. Environmental Health 2021, 20: 123. PMID: 34872587, PMCID: PMC8650256, DOI: 10.1186/s12940-021-00809-9.Peer-Reviewed Original ResearchConceptsNational Ambient Air Quality StandardsExposure to ambient nitrogen dioxideOmega-3 groupAmbient nitrogen dioxideOmega-3 PUFA intakeOmega-3 Polyunsaturated Fatty AcidsHeart rate variabilityBlood lipidsAmbient NO2NO2 concentrationsVascular functionLung functionExposure to fine particulate matterAir quality monitoring stationsConcentrations of ambient NO2Interquartile rangeAmbient Air Quality StandardsNitrogen dioxideShort-term exposure to NO2PUFA intakeCardiovascular outcomesFine particulate matterAir quality standardsQuality monitoring stationsResearch Triangle area of North Carolina
2018
Long-term effects of air pollution on ankle-brachial index
Zhang S, Wolf K, Breitner S, Kronenberg F, Stafoggia M, Peters A, Schneider A. Long-term effects of air pollution on ankle-brachial index. Environment International 2018, 118: 17-25. PMID: 29787898, DOI: 10.1016/j.envint.2018.05.025.Peer-Reviewed Original ResearchConceptsEffects of air pollutionLong-term exposure to PMExposure to PMAir pollutionParticulate matterLong-term exposure to air pollutionAdverse effects of air pollutionLand-use regression modelsLong-term effects of air pollutionExposure to air pollutionAnnual mean concentrationsHigh ankle-brachial indexAnkle-brachial indexAbnormal ankle-brachial indexLand-useMean concentrationsAerodynamic diameterPollutionNitrogen dioxideGeographic information systemPercentile incrementOdds ratioPrevalence of low ankle-brachial indexRegression modelsRegion of Augsburg
2017
Influence of air pollution on airway inflammation and disease activity in childhood-systemic lupus erythematosus
Alves A, de Azevedo Giacomin M, Braga A, Sallum A, Pereira L, Farhat L, Strufaldi F, de Faria Coimbra Lichtenfels A, de Santana Carvalho T, Nakagawa N, Silva C, Farhat S. Influence of air pollution on airway inflammation and disease activity in childhood-systemic lupus erythematosus. Clinical Rheumatology 2017, 37: 683-690. PMID: 29098476, DOI: 10.1007/s10067-017-3893-1.Peer-Reviewed Original ResearchConceptsChildhood-onset systemic lupus erythematosusAir pollutionIndividual exposure to air pollutionExposure to air pollutionFine particlesExposure to fine particlesChildhood-onset systemic lupus erythematosus patientsInfluence of air pollutionFine particulate matterInhaled fine particlesMeasurements of nitrogen dioxideIQR increaseParticulate matterAirway inflammationDisease activityLupus erythematosusPM2.5Nitrogen dioxideChildhood systemic lupus erythematosusPollutionSLEDAI-2KDisease activity parametersShort-term effectsSystemic lupus erythematosusFractional exhaled NO
2010
Seasonal Pattern of the Acute Mortality Effects of Air Pollution
Qian Z, Lin H, Stewart W, Kong L, Xu F, Zhou D, Zhu Z, Liang S, Chen W, Shah N, Stetter C, He Q. Seasonal Pattern of the Acute Mortality Effects of Air Pollution. Journal Of The Air & Waste Management Association 2010, 60: 481-488. PMID: 20437783, DOI: 10.3155/1047-3289.60.4.481.Peer-Reviewed Original ResearchConceptsAcute mortality effectsAir pollutionMortality effectsSeasonal patternConcentrations of particulate matterEffects of air pollutionPM10 daily concentrationsAir pollution levelsAmbient air pollutionGeneralized additive modelCity core areaPollution levelsDaily concentrationsPollution rangeParticulate matterAerodynamic diameterRespiratory mortalityPollutionNitrogen dioxideCause-specific mortalityDaily mortalitySulfur dioxideAdditive modelCore areaPM10
2009
Interaction of Ambient Air Pollution With Asthma Medication on Exhaled Nitric Oxide Among Asthmatics
Qian Z, Lin H, Chinchilli V, Lehman E, Duan Y, Craig T, Wilson W, Liao D, Lazarus S, Bascom R. Interaction of Ambient Air Pollution With Asthma Medication on Exhaled Nitric Oxide Among Asthmatics. Archives Of Environmental & Occupational Health 2009, 64: 168-176. PMID: 19864219, PMCID: PMC3713465, DOI: 10.1080/19338240903240616.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, InhalationAdolescentAdrenergic beta-AgonistsAdultAir PollutantsAir PollutionAlbuterolAnti-Inflammatory AgentsAsthmaBreath TestsChildDrug InteractionsFemaleHumansMaleMiddle AgedNitric OxideNitrogen DioxideOzoneParticulate MatterSalmeterol XinafoateSulfur DioxideUrban PopulationYoung Adult
2007
Short-Term Effects of Gaseous Pollutants on Cause-Specific Mortality in Wuhan, China
Qian Z, He Q, Lin H, Kong L, Liao D, Yang N, Bentley C, Xu S. Short-Term Effects of Gaseous Pollutants on Cause-Specific Mortality in Wuhan, China. Journal Of The Air & Waste Management Association 2007, 57: 785-793. PMID: 17687993, DOI: 10.3155/1047-3289.57.7.785.Peer-Reviewed Original ResearchConceptsGaseous pollutantsDaily mortalityAssociated with daily mortalityAcute mortality effectsCause-specific mortalityEvidence of acute effectsMortality effectsCity core areaAir pollution levelsEffects of gaseous pollutantsNO2 concentrationsDaily concentrationsPollution rangeAir pollution effectsExposure-response curvesGeneralized additive modelCardiopulmonary mortalityO3Exposure-response relationshipCause-specificNitrogen dioxideNO2Pollution levelsSulfur dioxideAir pollution
1989
Lower respiratory symptoms in children exposed to nitrogen dioxide from unvented combustion sources
Berwick M, Leaderer B, Stolwijk J, Zagraniski R. Lower respiratory symptoms in children exposed to nitrogen dioxide from unvented combustion sources. Environment International 1989, 15: 369-373. DOI: 10.1016/0160-4120(89)90050-0.Peer-Reviewed Original ResearchProspective epidemiologic studiesRespiratory symptomsRespiratory illnessIndoor air contaminant levelsRespiratory healthEpidemiologic studiesSubjects' homesExposure classificationStudy designSocioeconomic statusTwo-week periodYoung childrenNitrogen dioxide levelsChildrenAgeUnvented combustion sourcesNitrogen dioxideSymptomsIllnessWeeks
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply