Two mechanisms drive pronuclear migration in mouse zygotes
Scheffler K, Uraji J, Jentoft I, Cavazza T, Mönnich E, Mogessie B, Schuh M. Two mechanisms drive pronuclear migration in mouse zygotes. Nature Communications 2021, 12: 841. PMID: 33547291, PMCID: PMC7864974, DOI: 10.1038/s41467-021-21020-x.Peer-Reviewed Original ResearchMeSH KeywordsActinsAnimalsCell NucleusFemaleFertilizationForminsGene Expression Regulation, DevelopmentalGenes, ReporterGreen Fluorescent ProteinsLuminescent ProteinsMaleMiceMice, Inbred C57BLMice, Inbred CBAMicrofilament ProteinsMicrotubulesMovementNerve Tissue ProteinsOocytesrab GTP-Binding ProteinsRed Fluorescent ProteinSpermatozoaZygoteConceptsFertilization coneDynein-dependent mannerNetwork of microtubulesFormin 2Fertilized mouse eggsParental genomesPaternal chromosomesParental chromosomesPronuclear migrationParental pronucleiMouse eggsMale pronucleusMouse zygotesFemale pronucleusChromosomePronucleusActinFertilized eggsPronucleiCell centreZygotes
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