2021
Two mechanisms drive pronuclear migration in mouse zygotes
Scheffler K, Uraji J, Jentoft I, Cavazza T, Mönnich E, Mogessie B, Schuh M. Two mechanisms drive pronuclear migration in mouse zygotes. Nature Communications 2021, 12: 841. PMID: 33547291, PMCID: PMC7864974, DOI: 10.1038/s41467-021-21020-x.Peer-Reviewed Original ResearchMeSH KeywordsActinsAnimalsCell NucleusFemaleFertilizationForminsGene Expression Regulation, DevelopmentalGenes, ReporterGreen Fluorescent ProteinsLuminescent ProteinsMaleMiceMice, Inbred C57BLMice, Inbred CBAMicrofilament ProteinsMicrotubulesMovementNerve Tissue ProteinsOocytesrab GTP-Binding ProteinsRed Fluorescent ProteinSpermatozoaZygoteConceptsFertilization coneDynein-dependent mannerNetwork of microtubulesFormin 2Fertilized mouse eggsParental genomesPaternal chromosomesParental chromosomesPronuclear migrationParental pronucleiMouse eggsMale pronucleusMouse zygotesFemale pronucleusChromosomePronucleusActinFertilized eggsPronucleiCell centreZygotes
2014
Spire and Formin 2 Synergize and Antagonize in Regulating Actin Assembly in Meiosis by a Ping-Pong Mechanism
Montaville P, Jégou A, Pernier J, Compper C, Guichard B, Mogessie B, Schuh M, Romet-Lemonne G, Carlier M. Spire and Formin 2 Synergize and Antagonize in Regulating Actin Assembly in Meiosis by a Ping-Pong Mechanism. PLOS Biology 2014, 12: e1001795. PMID: 24586110, PMCID: PMC3934834, DOI: 10.1371/journal.pbio.1001795.Peer-Reviewed Original ResearchConceptsBarbed endsCaps filament barbed endsFilament barbed endsRegulate actin assemblyActin assembly dynamicsActin-binding proteinsRab11a-positive vesiclesPresence of actinPing-pong mechanismMechanisms of regulationActin assemblyActin meshworkFormin 2Fmn2ForminBinding proteinAssembly dynamicsArrested growthMolecular mechanismsActinMeiotic spindleProfilinMammalian oocytesProcess assemblyMouse oocytes
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply